Permethrin manufacturers and suppliers

Permethrin suppliers

Properties

Melting point:: 34-35°C

Boiling point:: bp0.05 220°

Density: 1.19

vapor pressure: 7×10^-5 Pa (20 °C)

refractive index: 1.6500 (estimate)

Flash point:: 10 °C

storage temp.: 0-6°C

solubility: DMF: 33 mg/ml; DMSO: 16 mg/ml; Ethanol: 14 mg/ml

form: Liquid

color: Light yellow to yellow

Water Solubility: insoluble

Merck: 13,7257

BRN: 5765325

Henry's Law Constant: 5.3×10⁰ mol/(m³Pa) at 25℃, Duchowicz et al. (2020)

Stability:: Stable. Incompatible with strong oxidising agents.

Major Application: agriculture
environmental

Cosmetics Ingredients Functions: ANTIMICROBIAL

InChI: 1S/C21H20Cl2O3/c1-21(2)17(12-18(22)23)19(21)20(24)25-13-14-7-6-10-16(11-14)26-15-8-4-3-5-9-15/h3-12,17,19H,13H2,1-2H3

InChIKey: RLLPVAHGXHCWKJ-UHFFFAOYSA-N

SMILES: CC1(C)C(\C=C(/Cl)Cl)C1C(=O)OCc2cccc(Oc3ccccc3)c2

LogP: 6.500

CAS DataBase Reference: 52645-53-1(CAS DataBase Reference)

IARC: 3 (Vol. 53) 1991

NIST Chemistry Reference: Permethrin(52645-53-1)

EPA Substance Registry System: Permethrin (52645-53-1)

Safety Information

Symbol(GHS): GHS07,GHS09

Signal word: Warning

Hazard statements: H302+H332-H317-H410

Precautionary statements: P261-P273-P280-P301+P312-P302+P352-P304+P340+P312

PPE: dust mask type N95 (US), Eyeshields, Faceshields, Gloves

Hazard Codes: Xn,N,T,F

Risk Statements: 20/22-43-50/53-39/23/24/25-23/24/25-11-51/53-36-20/21/22

Safety Statements: 13-24-36/37/39-60-61-45-36/37-16-7-26

RIDADR: UN1230 3/PG 2

WGK Germany: 3

RTECS: GZ1255000

HS Code: 29162090

Storage Class: 11 - Combustible Solids

Hazard Classifications: Acute Tox. 4 Inhalation
Acute Tox. 4 Oral
Aquatic Acute 1
Aquatic Chronic 1
Skin Sens. 1

Hazardous Substances Data: 52645-53-1(Hazardous Substances Data)

Toxicity: LD50 orally in female rats: 3801 mg/kg (Metker); LD50 in 8 day old rats, male adult rats (mg/kg): 340.5, 1500.0 orally (Cantalamessa)

Use

Permethrin is 3-(2,2-Dichloroethenyl)-2,2-dimethylcyclopropanecarboxylicacid (3-phenoxyphenyl)methylester or 3-(phenoxyphenyl)methyl (±)-cis, trans-3-(2,2-dichloroethenyl)-2,2-dimethylcyclopropanecarboxylate(Nix). This synthetic pyrethrinoid compound is more stablechemically than most natural pyrethrins and is at least as activeas an insecticide. Of the four isomers present, the1(R),trans and 1(R),cis-isomers are primarily responsiblefor the insecticidal activity. The commercial product is amixture consisting of 60% trans and 40% cis racemic isomers.It occurs as colorless to pale yellow low-melting crystalsor as a pale yellow liquid and is insoluble in water butsoluble in most organic solvents.Permethrin exerts a lethal action against lice, ticks, mites,and fleas. It acts on the nerve cell membranes of the parasitesto disrupt sodium channel conductance. It is used as apediculicide for the treatment of head lice. A single applicationof a 1% solution effects cures in more than 99% ofcases. The most frequent side effect is pruritus, which occurredin about 6% of the patients tested.

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