Probucol manufacturers and suppliers

Probucol suppliers

Properties

Melting point:: 126-128°C

Boiling point:: 571.58°C (rough estimate)

Density: 1.0008 (rough estimate)

refractive index: 1.5341 (estimate)

storage temp.: Keep in dark place,Sealed in dry,Room Temperature

solubility: Chloroform (Slightly), Ethyl Acetate (Slightly)

form: Solid

pka: 10.27±0.70(Predicted)

color: White to Off-White

Merck: 14,7755

Major Application: forensics and toxicology
pharmaceutical (small molecule)

InChI: InChI=1S/C31H48O2S2/c1-27(2,3)21-15-19(16-22(25(21)32)28(4,5)6)34-31(13,14)35-20-17-23(29(7,8)9)26(33)24(18-20)30(10,11)12/h15-18,32-33H,1-14H3

InChIKey: FYPMFJGVHOHGLL-UHFFFAOYSA-N

SMILES: C(SC1=CC(C(C)(C)C)=C(O)C(C(C)(C)C)=C1)(SC1=CC(C(C)(C)C)=C(O)C(C(C)(C)C)=C1)(C)C

CAS DataBase Reference: 23288-49-5(CAS DataBase Reference)

Safety Information

Symbol(GHS): GHS07

Signal word: Warning

Hazard statements: H302

Precautionary statements: P280-P305+P351+P338

PPE: Eyeshields, Gloves, type N95 (US)

WGK Germany: 2

RTECS: AL3705000

HS Code: 2930902000

Storage Class: 11 - Combustible Solids

Use

Probucol, 4,4＇ -[(1-methylethylidene)bis(thio)]bis[2,6-bis(1,1-dimethylethyl)phenol], DH-581(Lorelco), is a chemical agent that was developed for the plasticsand rubber industry in the 1960s. The probucol moleculehas two tertiary butylphenol groups linked by a dithiopropylidenebridge, giving it a high lipophilic character with strongantioxidant properties. In humans, it causes reduction of bothliver and serum cholesterol levels, but it does not alter plasmatriglycerides. It reduces LDL and (to a lesser extent) HDLlevels by a unique mechanism that is still not clearly delineated.The reduction of HDL may be caused by the ability ofprobucol to inhibit the synthesis of apoprotein A-1, a majorprotein component of HDL. It is effective at reducing levelsof LDL and is used in hyperlipoproteinemias characterized byelevated LDL levels.

You can find Probucol suppliers, manufacturers, and distributors from countries such as China, United States and the United Kingdom here. Browse to the tetrahydrofuran product information displayed by the supplier, as well as the supplier's contact and capability information.