Propylthiouracil manufacturers and suppliers

Propylthiouracil suppliers

Properties

Melting point:: 218-220 °C (lit.)

Density: 1.1880 (rough estimate)

bulk density: 159kg/m3

refractive index: 1.5960 (estimate)

Flash point:: 300 °C

storage temp.: 2-8°C

solubility: 1.1g/l

pka: pKa 7.8; 8.3 (Uncertain)

form: Solid

color: White

PH: 6-7.5 (5g/l, H2O, 20℃)(slurry)

Water Solubility: 1.1 g/L

Merck: 14,7869

BRN: 130039

Henry's Law Constant: 9.0×10³ mol/(m³Pa) at 25℃, HSDB (2015)

BCS Class: 3

Stability:: Stable. Combustible. Incompatible with strong oxidizing agents, strong acids, strong bases. Light sensitive.

InChI: 1S/C7H10N2OS/c1-2-3-5-4-6(10)9-7(11)8-5/h4H,2-3H2,1H3,(H2,8,9,10,11)

InChIKey: KNAHARQHSZJURB-UHFFFAOYSA-N

SMILES: CCCC1=CC(=O)NC(=S)N1

CAS DataBase Reference: 51-52-5(CAS DataBase Reference)

NIST Chemistry Reference: Tegretol(51-52-5)

IARC: 2B (Vol. Sup 7, 79) 2001

EPA Substance Registry System: Propylthiouracil (51-52-5)

Safety Information

Symbol(GHS): GHS07,GHS08

Signal word: Warning

Hazard statements: H302-H351

Precautionary statements: P280-P301+P312+P330

PPE: Eyeshields, Gloves, type P3 (EN 143) respirator cartridges

Hazard Codes: Xn,Xi

Risk Statements: 22-40

Safety Statements: 36/37-45

WGK Germany: 3

RTECS: YR1400000

Hazard Note: Harmful/Irritant

TSCA: TSCA listed

HS Code: 29335995

Storage Class: 11 - Combustible Solids

Hazard Classifications: Acute Tox. 4 Oral
Carc. 2

Hazardous Substances Data: 51-52-5(Hazardous Substances Data)

Toxicity: LD50 orally in Rabbit: 1250 mg/kg

Use

Propylthiouracil is useful in the treatment of hyperthyroidism.There is a delay in appearance of its effects because propylthiouracildoes not interfere with the activity of thyroid hormonesalready formed and stored in the thyroid gland. Thislag period may vary from several days to weeks, dependingon the condition of the patient. The need for three equallyspaced doses during a 24-hour period is often stressed, butevidence now indicates that a single daily dose is as effectiveas multiple daily doses in the treatment of most hyperthyroidpatients.

You can find Propylthiouracil suppliers, manufacturers, and distributors from countries such as China, United States and the United Kingdom here. Browse to the tetrahydrofuran product information displayed by the supplier, as well as the supplier's contact and capability information.