Rocuronium bromide manufacturers and suppliers

Rocuronium bromide suppliers

Properties

Melting point:: 162-1640C

alpha: D20 +18.7° (c = 1.03 in CHCl3)

storage temp.: Inert atmosphere,2-8°C

solubility: H2O: soluble100mg/mL, clear, light yellow

form: Powder to Crystal

color: White to Yellow

Water Solubility: H2O: 100mg/mL, clear, light yellow

Merck: 14,8246

Stability:: Hygroscopic

InChIKey: OYTJKRAYGYRUJK-FMCCZJBLSA-M

SMILES: [Br-].CC(=O)O[C@H]1[C@H](C[C@H]2[C@@H]3CC[C@H]4C[C@H](O)[C@H](C[C@]4(C)[C@H]3CC[C@]12C)N5CCOCC5)[N+]6(CCCC6)CC=C

CAS DataBase Reference: 119302-91-9(CAS DataBase Reference)

Safety Information

Symbol(GHS): GHS07,GHS06

Signal word: Danger

Hazard statements: H331-H312-H302-H330

Precautionary statements: P261-P271-P304+P340-P311-P321-P403+P233-P405-P501-P280-P302+P352-P312-P322-P363-P501-P260-P271-P284-P304+P340-P310-P320-P403+P233-P405-P501-P264-P270-P301+P312-P330-P501

target organs: Respiratory system

PPE: Eyeshields, Gloves, type N95 (US)

WGK Germany: 3

HS Code: 2934990002

Storage Class: 6.1C - Combustible acute toxic Cat.3
toxic compounds or compounds which causing chronic effects

Hazard Classifications: Acute Tox. 3 Oral
STOT SE 3

Use

Rocuronium bromide is a short-acting nondepolarizing steroidal neuromuscular blocker introduced in the U.S.A as Zemuron and in the United Kingdom as Esmeron. k is indicated for use as an adjunct to general anesthesia to facilitate endotracheal intubation and to provide skeletal muscle relaxation during surgery or mechanical ventilation. Rocuroniurn bromide has a significantly more rapid onset than other intermediate acting neuromuscular blockers, comparable to succinylcholine but with a very stable cardiovascular profile and has an improved side effect profile. It has been reported that good to excellent intubation conditions were achieved only one minute after a bolus dose of 600μg/kg of rocuronium bromide. It has a short duration of action, therefore, is useful for rapid sequence intubation without unacceptable delays in the spontaneous recovery of neuromuscular function.

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