Sulfanilamide manufacturers and suppliers

Sulfanilamide suppliers

Properties

Melting point:: 164-166 °C(lit.)

Boiling point:: 400.5±47.0 °C(Predicted)

bulk density: 500kg/m3

Density: 1.08

vapor pressure: 0.00001 hPa (70 °C)

refractive index: 1.6490 (estimate)

storage temp.: 2-8°C

solubility: 5.37g/l

pka: pKa 10.65(H2O t = 25.0±0.5 I = 0.2) (Uncertain)

form: powder

color: white to faintly beige

Odor: Odorless

PH: 5.8-6.1 (5g/l, H2O, 20℃)

PH Range: 5.8 - 6.1 (0.5% aq.sol.)

Water Solubility: 7.5 g/L at 25 ºC

λmax: 257nm(H2O)(lit.)

Merck: 14,8925

BRN: 511852

InChIKey: FDDDEECHVMSUSB-UHFFFAOYSA-N

LogP: -0.620

CAS DataBase Reference: 63-74-1(CAS DataBase Reference)

NIST Chemistry Reference: Benzenesulfonamide, 4-amino-(63-74-1)

EPA Substance Registry System: Sulfanilamide (63-74-1)

Safety Information

Symbol(GHS): GHS07,GHS05

Signal word: Warning

Hazard statements: H303-H315-H314-H319-H335

Precautionary statements: P261-P280a-P304+P340-P305+P351+P338-P405-P501a-P260h-P301+P330+P331-P303+P361+P353

Hazard Codes: Xn

Risk Statements: 40

Safety Statements: 24/25-36-22

WGK Germany: 3

RTECS: WO8400000

F: 10

TSCA: Yes

HazardClass: 8

HS Code: 29350090

Hazardous Substances Data: 63-74-1(Hazardous Substances Data)

Toxicity: LD50 orally in mice: 3.8 g/kg (Marshall)

Use

Sulfanilamide is a sulfonamide antibiotic. Sulfonamide antibiotic that blocks the synthesis of dihydrofolic acid by inhibiting the enzyme dihydropteroate synthase.Formulations containing sulfanilamide have been used to treat T. vaginalis infections. It is bacteriostatic against Streptococci in vitro at a concentration of 20 g/ml and inhibits the growth of 106 clinically isolated strains of Gonococcus.Sulfanilamide reduces the concentration of Streptococcus in rabbit plasma ex vivo following four doses of 20 ml of a 2% sulfanilamide solution. Mode of Action: A competitive inhibitor of dihydropteroate synthestase to block the synthesis of folic acid. Anti-microbial Spectrum: Gram positive, Gram negative, Chlamydia Mode of Resistance: Alteration of dihydropteroate synthase or alternative pathway for folic acid synthesis.

You can find Sulfanilamide suppliers, manufacturers, and distributors from countries such as CHINA, United States and the India here. Browse to the tetrahydrofuran product information displayed by the supplier, as well as the supplier's contact and capability information.