Thiabendazole manufacturers and suppliers

Thiabendazole suppliers

Properties

Melting point:: 298-301°C

Boiling point:: 446.0±37.0 °C(Predicted)

Density: 1.2271 (rough estimate)

vapor pressure: Negligible at room temperature

refractive index: 1.5500 (estimate)

storage temp.: Sealed in dry,Room Temperature

solubility: Soluble in methanol and dimethyl sulfoxide.

pka: pKa 4.7 (Uncertain)

form: powder

color: light yellow

Water Solubility: 0.005 g/100 mL

Merck: 14,9289

BRN: 611403

Henry's Law Constant: 4.7×10⁵ mol/(m³Pa) at 25℃, Duchowicz et al. (2020)

Cosmetics Ingredients Functions: ANTIMICROBIAL

InChI: 1S/C10H7N3S/c1-2-4-8-7(3-1)12-10(13-8)9-5-14-6-11-9/h1-6H,(H,12,13)

InChIKey: WJCNZQLZVWNLKY-UHFFFAOYSA-N

SMILES: c1ccc2[nH]c(nc2c1)-c3cscn3

LogP: 2.470

CAS DataBase Reference: 148-79-8(CAS DataBase Reference)

NIST Chemistry Reference: Thiabendazole(148-79-8)

EPA Substance Registry System: Thiabendazole (148-79-8)

Safety Information

Symbol(GHS): GHS09

Signal word: Warning

Hazard statements: H410

Precautionary statements: P273-P501

PPE: Eyeshields, Gloves

Hazard Codes: N,Xi

Risk Statements: 50/53-36/37/38

Safety Statements: 60-61-36-26

RIDADR: UN 3077 9/PG 3

WGK Germany: 2

RTECS: DE0700000

TSCA: TSCA listed

HazardClass: 9

PackingGroup: III

HS Code: 29341000

Storage Class: 11 - Combustible Solids

Hazard Classifications: Aquatic Acute 1
Aquatic Chronic 1

Hazardous Substances Data: 148-79-8(Hazardous Substances Data)

Toxicity: LD50 in mice, rats, rabbits (g/kg): 3.6, 3.1, >3.8 orally (Robinson)

Use

2-(4-Thiazolyl)benzimidazole (Mintezol) occurs as a whitecrystalline substance that is only slightly soluble in waterbut is soluble in strong mineral acids. Thiabendazole is abasic compound with a pKa of 4.7 that forms complexeswith metal ions.Thiabendazole inhibits the helminth-specific enzymefumarate reductase. It is not known whether metal ionsare involved or if the inhibition of the enzyme is related tothiabendazole’s anthelmintic effect. Benzimidazole anthelminticdrugs such as thiabendazole and mebendazolealso arrest nematode cell division in metaphase by interferingwith microtubule assembly. They exhibit a highaffinity for tubulin, the precursor protein for microtubulesynthesis.Thiabendazole has broad-spectrum anthelmintic activity.It is used to treat enterobiasis, strongyloidiasis (threadworminfection), ascariasis, uncinariasis (hookworm infection), andtrichuriasis (whipworm infection). It has also been used torelieve symptoms associated with cutaneous larva migrans(creeping eruption) and the invasive phase of trichinosis. Inaddition to its use in human medicine, thiabendazole iswidely used in veterinary practice to control intestinalhelminths in livestock.

You can find Thiabendazole suppliers, manufacturers, and distributors from countries such as China, United States and the United Kingdom here. Browse to the tetrahydrofuran product information displayed by the supplier, as well as the supplier's contact and capability information.