Zileuton manufacturers and suppliers

Zileuton suppliers

Properties

Melting point:: 157-158°C

Boiling point:: 449.4±47.0 °C(Predicted)

Density: 1.401±0.06 g/cm3(Predicted)

storage temp.: room temp

solubility: DMSO: ≥20mg/mL at ~60°C (warm up to 60 C for 5min)

form: powder

pka: pKa 10.3(H2O t undefined I undefined) (Uncertain)

color: white to off-white

Stability:: Stable for 1 year from date of purchase as supplied. Solutions in DMSO may be stored at -20°C for up to 1 month.

InChI: 1S/C11H12N2O2S/c1-7(13(15)11(12)14)10-6-8-4-2-3-5-9(8)16-10/h2-7,15H,1H3,(H2,12,14)

InChIKey: MWLSOWXNZPKENC-UHFFFAOYSA-N

SMILES: CC(N(O)C(N)=O)c1cc2ccccc2s1

CAS DataBase Reference: 111406-87-2(CAS DataBase Reference)

Safety Information

Symbol(GHS): GHS07,GHS08

Signal word: Warning

Hazard statements: H302-H361d

Precautionary statements: P202-P264-P270-P280-P301+P312-P308+P313

Hazard Codes: Xn

Risk Statements: 22-36

Safety Statements: 26

WGK Germany: 1

HS Code: 2934990002

Storage Class: 11 - Combustible Solids

Hazard Classifications: Acute Tox. 4 Oral
Repr. 2

Use

Zileuton, a benzothiophene N-hydroxyurea, is the only approved inhibitor of 5-lipoxygenase. It is believed to intervene with allergic and inflammatory diseases by suppression of leukotriene (LT) biosynthesis. The compound belongs to the class of iron ligand-type inhibitors of 5-lipoxygenase that not only chelates the active site iron of the enzyme but also possesses weak-reducing properties. Zileuton is used as a type of drug for the prophylaxis and chronic treatment of asthma.

You can find Zileuton suppliers, manufacturers, and distributors from countries such as China, United States and the India here. Browse to the tetrahydrofuran product information displayed by the supplier, as well as the supplier's contact and capability information.