3-Pyridinecarboxamide, 6-(3-fluorophenyl)-N-[1-(2,2,2-trifluoroethyl)-4-piperidinyl]-
![3-Pyridinecarboxamide, 6-(3-fluorophenyl)-N-[1-(2,2,2-trifluoroethyl)-4-piperidinyl]- price.](/CAS/GIF/1033836-12-2.gif)
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- $51 - $3811.5
- Product name: 3-Pyridinecarboxamide, 6-(3-fluorophenyl)-N-[1-(2,2,2-trifluoroethyl)-4-piperidinyl]-
- CAS: 1033836-12-2
- MF: C19H19F4N3O
- MW: 381.37
- EINECS:
- MDL Number:MFCD18206776
- Synonyms:HPGDS inhibitor 1;6-(3-Fluorophenyl)-N-[1-(2,2,2-trifluoroethyl)-4-piperidinyl]-3-pyridinecarboxamide;6-(3-fluorophenyl)-N-(1-(2,2,2-trifluoroethyl)piperidin-4-yl)nicotinaMide;HPGDS inhibitor 1, >=98%;Prostaglandin D Synthase (hematopoietic-type) Inhibitor I;CS-1438;MDK36122;HPGDS inhibitor 1, 10 mM in DMSO
41 prices
Selected condition：
Brand
- aablocks
- ACHEMBLOCK
- Ambeed
- American Custom Chemicals Corporation
- ApexBio Technology
- Arctom
- Biorbyt Ltd
- Cayman Chemical
- Chemenu
- ChemScene
- Crysdot
- DC Chemicals
- Matrix Scientific
Package
- 5mg
- 10mM*1mLinDMSO
- 1mg
- 10mM*1mLinDMSO(Solution)
- 10mg
- 25.00mg
- 25mg
- 50.00mg
- 50mg
- 100.00mg
- 100mg
- 250mg
- 1g
- 5G
- 10mM*1mLinDMSO(Solid+Solvent)
- 1000mg
- Manufactureraablocks
- Product numberAA008TE2
- Product descriptionHpgds Inhibitor 1 95%
- Packaging1g
- Price$907
- Updated2026-05-28
- Buy
- Manufactureraablocks
- Product numberAA008TE2
- Product descriptionHpgds Inhibitor 1 95%
- Packaging250mg
- Price$318
- Updated2026-05-28
- Buy
- Manufactureraablocks
- Product numberAA008TE2
- Product descriptionHpgds Inhibitor 1 98%
- Packaging100mg
- Price$132
- Updated2026-05-28
- Buy
- Manufactureraablocks
- Product numberAA008TE2
- Product descriptionHpgds Inhibitor 1 98%
- Packaging50mg
- Price$86
- Updated2026-05-28
- Buy
- Manufactureraablocks
- Product numberAA008TE2
- Product descriptionHpgds Inhibitor 1 98%
- Packaging25mg
- Price$51
- Updated2026-05-28
- Buy
- ManufacturerACHEMBLOCK
- Product numberO33818
- Product descriptionHPGDS-inhibitor-1 98%
- Packaging1G
- Price$1220
- Updated2026-05-27
- Buy
- ManufacturerACHEMBLOCK
- Product numberO33818
- Product descriptionHPGDS-inhibitor-1 98%
- Packaging100MG
- Price$205
- Updated2026-05-27
- Buy
- ManufacturerAmbeed
- Product numberA414719
- Product descriptionHPGDSinhibitor1 98+%
- Packaging100mg
- Price$1282
- Updated2021-12-16
- Buy
- ManufacturerAmerican Custom Chemicals Corporation
- Product numberHCH0316558
- Product description6-(3-FLUOROPHENYL)-N-[1-(2,2,2-TRIFLUOROETHYL)-4-PIPERIDINYL]-3-PYRIDINECARBOXAMIDE 95.00%
- Packaging5G
- Price$3811.5
- Updated2021-12-16
- Buy
- ManufacturerApexBio Technology
- Product numberB1046
- Product descriptionHPGDS inhibitor 1
- Packaging50mg
- Price$958
- Updated2026-05-06
- Buy
- ManufacturerApexBio Technology
- Product numberB1046
- Product descriptionHPGDS inhibitor 1
- Packaging100mg
- Price$1383
- Updated2026-05-06
- Buy
- ManufacturerApexBio Technology
- Product numberB1046
- Product descriptionHPGDS inhibitor 1
- Packaging5mg
- Price$258
- Updated2026-05-06
- Buy
- ManufacturerApexBio Technology
- Product numberB1046
- Product descriptionHPGDS inhibitor 1
- Packaging10mg
- Price$364
- Updated2026-05-06
- Buy
- ManufacturerArctom
- Product numberHY-10439
- Product descriptionHPGDS inhibitor 1 99.42%
- Packaging25mg
- Price$367
- Updated2026-05-26
- Buy
- ManufacturerArctom
- Product numberHY-10439
- Product descriptionHPGDS inhibitor 1 99.42%
- Packaging10mg
- Price$214
- Updated2026-05-26
- Buy
- ManufacturerArctom
- Product numberHY-10439
- Product descriptionHPGDS inhibitor 1 99.42%
- Packaging5mg
- Price$138
- Updated2026-05-26
- Buy
| Manufacturer | Product number | Product description | Packaging | Price | Updated | Buy |
|---|---|---|---|---|---|---|
| aablocks | AA008TE2 | Hpgds Inhibitor 1 95% | 1g | $907 | 2026-05-28 | Buy |
| aablocks | AA008TE2 | Hpgds Inhibitor 1 95% | 250mg | $318 | 2026-05-28 | Buy |
| aablocks | AA008TE2 | Hpgds Inhibitor 1 98% | 100mg | $132 | 2026-05-28 | Buy |
| aablocks | AA008TE2 | Hpgds Inhibitor 1 98% | 50mg | $86 | 2026-05-28 | Buy |
| aablocks | AA008TE2 | Hpgds Inhibitor 1 98% | 25mg | $51 | 2026-05-28 | Buy |
| ACHEMBLOCK | O33818 | HPGDS-inhibitor-1 98% | 1G | $1220 | 2026-05-27 | Buy |
| ACHEMBLOCK | O33818 | HPGDS-inhibitor-1 98% | 100MG | $205 | 2026-05-27 | Buy |
| Ambeed | A414719 | HPGDSinhibitor1 98+% | 100mg | $1282 | 2021-12-16 | Buy |
| American Custom Chemicals Corporation | HCH0316558 | 6-(3-FLUOROPHENYL)-N-[1-(2,2,2-TRIFLUOROETHYL)-4-PIPERIDINYL]-3-PYRIDINECARBOXAMIDE 95.00% | 5G | $3811.5 | 2021-12-16 | Buy |
| ApexBio Technology | B1046 | HPGDS inhibitor 1 | 50mg | $958 | 2026-05-06 | Buy |
| ApexBio Technology | B1046 | HPGDS inhibitor 1 | 100mg | $1383 | 2026-05-06 | Buy |
| ApexBio Technology | B1046 | HPGDS inhibitor 1 | 5mg | $258 | 2026-05-06 | Buy |
| ApexBio Technology | B1046 | HPGDS inhibitor 1 | 10mg | $364 | 2026-05-06 | Buy |
| Arctom | HY-10439 | HPGDS inhibitor 1 99.42% | 25mg | $367 | 2026-05-26 | Buy |
| Arctom | HY-10439 | HPGDS inhibitor 1 99.42% | 10mg | $214 | 2026-05-26 | Buy |
| Arctom | HY-10439 | HPGDS inhibitor 1 99.42% | 5mg | $138 | 2026-05-26 | Buy |
Properties
Boiling point :487.2±45.0 °C(Predicted)
Density :1.33±0.1 g/cm3(Predicted)
storage temp. :2-8°C
solubility :Soluble in DMSO
form :crystalline solid
pka :9.55±0.20(Predicted)
color :White to off-white
Density :1.33±0.1 g/cm3(Predicted)
storage temp. :2-8°C
solubility :Soluble in DMSO
form :crystalline solid
pka :9.55±0.20(Predicted)
color :White to off-white
Safety Information
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Description
Prostaglandin D2 is synthesized by PGD synthase (hematopoietic-type) (H-PGDS) in mast cells and is released in large quantities during allergic and asthmatic anaphylaxis. Thus, H-PGDS is an important target for the development of inhibitors for therapeutic use against these diseases. H-PGDS inhibitor I selectively blocks HPGDS (IC50s = 0.7 and 32 nM in enzyme and cellular assays, respectively) with little activity against the related human enzymes L-PGDS, mPGES, COX-1, COX-2, and 5-LOX. It is orally bioavailable and has been shown to dampen airway hyper-responsiveness in a model of antigen-induced airway response in allergic sheep.Related product price
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1033836-12-2
$51-3811.5