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ChemicalBook >> CAS DataBase List >> 4-oxo-27-TBDMS Withaferin A

4-oxo-27-TBDMS Withaferin A

4-oxo-27-TBDMS Withaferin A price.
  • $90 - $4050
  • Product name: 4-oxo-27-TBDMS Withaferin A
  • CAS: 1214886-31-3
  • MF: C34H50O6Si
  • MW: 582.85
  • EINECS:
  • MDL Number:
  • Synonyms:4-oxo-27-TBDMS Withaferin A;Ergosta-2,24-dien-26-oic acid, 27-[[(1,1-dimethylethyl)dimethylsilyl]oxy]-5,6-epoxy-22-hydroxy-1,4-dioxo-, δ-lactone, (5β,6β,22R)-;(5β,6β,22R)-27-[[(1,1-dimethylethyl)dimethylsilyl]oxy]-5,6-epoxy-22-hydroxy-1,4-dioxo-ergosta-2,24-dien-26-oic acid, δ-lactone
Price8 Properties Safety Information Description
8 prices
Selected condition：
Brand
  • Biosynth
  • Cayman Chemical
  • ChemScene
Package
  • 1mg
  • 5mg
  • 10mg
  • 25mg
  • 50mg
  • ManufacturerBiosynth
  • Product numberPYB88631
  • Product description4-Oxo-27-TBDMS withaferin A
  • Packaging5mg
  • Price$843.7
  • Updated2026-06-04
  • Buy
  • ManufacturerBiosynth
  • Product numberPYB88631
  • Product description4-Oxo-27-TBDMS withaferin A
  • Packaging10mg
  • Price$1349.9
  • Updated2026-06-04
  • Buy
  • ManufacturerBiosynth
  • Product numberPYB88631
  • Product description4-Oxo-27-TBDMS withaferin A
  • Packaging25mg
  • Price$2531
  • Updated2026-06-04
  • Buy
  • ManufacturerBiosynth
  • Product numberPYB88631
  • Product description4-Oxo-27-TBDMS withaferin A
  • Packaging50mg
  • Price$4050
  • Updated2026-06-04
  • Buy
  • ManufacturerCayman Chemical
  • Product number28323
  • Product description4-oxo-27-TBDMS Withaferin A ≥98%
  • Packaging1mg
  • Price$90
  • Updated2026-04-30
  • Buy
  • ManufacturerCayman Chemical
  • Product number28323
  • Product description4-oxo-27-TBDMS Withaferin A ≥98%
  • Packaging5mg
  • Price$262
  • Updated2026-04-30
  • Buy
  • ManufacturerCayman Chemical
  • Product number28323
  • Product description4-oxo-27-TBDMS Withaferin A ≥98%
  • Packaging10mg
  • Price$436
  • Updated2026-04-30
  • Buy
  • ManufacturerChemScene
  • Product numberCS-0433497
  • Product description27-TBDMS-4-Dehydrowithaferin A
  • Packaging1mg
  • Price$206
  • Updated2026-06-04
  • Buy
Manufacturer Product number Product description Packaging Price Updated Buy
Biosynth PYB88631 4-Oxo-27-TBDMS withaferin A 5mg $843.7 2026-06-04 Buy
Biosynth PYB88631 4-Oxo-27-TBDMS withaferin A 10mg $1349.9 2026-06-04 Buy
Biosynth PYB88631 4-Oxo-27-TBDMS withaferin A 25mg $2531 2026-06-04 Buy
Biosynth PYB88631 4-Oxo-27-TBDMS withaferin A 50mg $4050 2026-06-04 Buy
Cayman Chemical 28323 4-oxo-27-TBDMS Withaferin A ≥98% 1mg $90 2026-04-30 Buy
Cayman Chemical 28323 4-oxo-27-TBDMS Withaferin A ≥98% 5mg $262 2026-04-30 Buy
Cayman Chemical 28323 4-oxo-27-TBDMS Withaferin A ≥98% 10mg $436 2026-04-30 Buy
ChemScene CS-0433497 27-TBDMS-4-Dehydrowithaferin A 1mg $206 2026-06-04 Buy

Properties

Boiling point :651.3±55.0 °C(Predicted)
Density :1.14±0.1 g/cm3(Predicted)
storage temp. :Store at -20°C
solubility :DMF: 5mg/mL; DMSO: 5mg/mL; DMSO:PBS (pH 7.2) (1:1): 0.5mg/mL

Safety Information

Symbol(GHS): Flame (GHS02)Exclamation Mark (GHS07)
Signal word: Danger
Hazard statements:
Code Hazard statements Hazard class Category Signal word Pictogram P-Codes
H225 Highly Flammable liquid and vapour Flammable liquids Category 2 Danger P210,P233, P240, P241, P242, P243,P280, P303+ P361+P353, P370+P378,P403+P235, P501
H319 Causes serious eye irritation Serious eye damage/eye irritation Category 2A Warning P264, P280, P305+P351+P338,P337+P313P
Precautionary statements:
P210 Keep away from heat/sparks/open flames/hot surfaces. — No smoking.
P233 Keep container tightly closed.
P240 Ground/bond container and receiving equipment.
P241 Use explosion-proof electrical/ventilating/lighting/…/equipment.
P242 Use only non-sparking tools.
P243 Take precautionary measures against static discharge.
P264 Wash hands thoroughly after handling.
P264 Wash skin thouroughly after handling.
P280 Wear protective gloves/protective clothing/eye protection/face protection.
P303+P361+P353 IF ON SKIN (or hair): Remove/Take off Immediately all contaminated clothing. Rinse SKIN with water/shower.
P305+P351+P338 IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continuerinsing.
P337+P313 IF eye irritation persists: Get medical advice/attention.
P370+P378 In case of fire: Use … for extinction.
P403+P235 Store in a well-ventilated place. Keep cool.
P501 Dispose of contents/container to..…

Description

4-oxo-27-TBDMS Withaferin A is a derivative of the steroidal lactone withaferin A that has anticancer activity.1 It is cytotoxic to A2780 ovarian cancer cells (IC50 = 17 μM) but not to carboplatin-resistant A2780 (A2780/CP70) cells (IC50 = >100 μM). It is selective for A2780 cells over non-cancerous ARPE19 cells (IC50 = 1,660 μM). 4-oxo-27-TBDMS Withaferin A induces DNA fragmentation in A2780 cells.

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Suppliers and manufacturers

TargetMol Chemicals Inc.
4-oxo-27-TBDMS Withaferin A
$287.00
4-oxo-27-TBDMS Withaferin A CAS:1214886-31-3
Shanghai Hongye Biotechnology Co. Ltd ChemeGen(Shanghai) Biotechnology Co.,Ltd. Beijing Biocreative Technology Co., Ltd. Shanghai Yiyan Biotechnology Co. , Ltd. Shanghai Yifei Biotechnology Co. , Ltd. TargetMol Chemicals Inc.