5alpha-Cholestan-3beta,5alpha-diol-6-one
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- $36 - $432
- Product name: 5alpha-Cholestan-3beta,5alpha-diol-6-one
- CAS: 13027-33-3
- MF: C27H46O3
- MW: 418.65
- EINECS:
- MDL Number:MFCD00271438
- Synonyms:(3S,5R,8S,9S,10R,13R,14S,17R)-3,5-Dihydroxy-10,13-dimethyl-17-((R)-6-methylheptan-2-yl)tetradecahydro-1H-cyclopenta[a]phenanthren-6(10H)-one;5ALPHA-HYDROXY-6-KETO CHOLESTEROL;yakkasterone;3β,5-Dihydroxy-5α-cholestan-6-one;YS-64;5α-hydroxy-6-keto Cholesterol;CHOLESTANE-6-OXO-3,5-DIOL;CHOLESTANE-6-OXO-3BETA,5ALPHA-DIOL
12 prices
Selected condition:
Brand
- aablocks
- AK Scientific
- Cayman Chemical
- ChemScene
- TRC
- Usbiological
Package
- 1mg
- 2.5mg
- 5mg
- 10mg
- Manufactureraablocks
- Product numberAA000U4U
- Product description5α-hydroxy-6-keto Cholesterol ≥98%
- Packaging5mg
- Price$160
- Updated2026-05-25
- Buy
- Manufactureraablocks
- Product numberAA000U4U
- Product description5α-hydroxy-6-keto Cholesterol ≥98%
- Packaging10mg
- Price$303
- Updated2026-05-25
- Buy
- ManufacturerAK Scientific
- Product number1446AH
- Product description5alpha-Cholestan-3beta,5alpha-diol-6-one
- Packaging1mg
- Price$133
- Updated2021-12-16
- Buy
- ManufacturerAK Scientific
- Product number1446AH
- Product description5alpha-Cholestan-3beta,5alpha-diol-6-one
- Packaging10mg
- Price$403
- Updated2021-12-16
- Buy
- ManufacturerCayman Chemical
- Product number10007601
- Product description5α-hydroxy-6-keto Cholesterol ≥98%
- Packaging5mg
- Price$160
- Updated2026-04-30
- Buy
- ManufacturerCayman Chemical
- Product number10007601
- Product description5α-hydroxy-6-keto Cholesterol ≥98%
- Packaging1mg
- Price$36
- Updated2026-04-30
- Buy
- ManufacturerCayman Chemical
- Product number10007601
- Product description5α-hydroxy-6-keto Cholesterol ≥98%
- Packaging10mg
- Price$303
- Updated2026-04-30
- Buy
- ManufacturerChemScene
- Product numberCS-0082542
- Product description5α-Hydroxy-6-keto cholesterol 99.9%
- Packaging5mg
- Price$369
- Updated2026-06-04
- Buy
- ManufacturerTRC
- Product numberC432525
- Product description5α-hydroxy-6-ketoCholesterol
- Packaging1mg
- Price$45
- Updated2021-12-16
- Buy
- ManufacturerTRC
- Product numberC432525
- Product description5α-hydroxy-6-ketoCholesterol
- Packaging2.5mg
- Price$90
- Updated2021-12-16
- Buy
- ManufacturerUsbiological
- Product number437396
- Product description5alpha-hydroxy-6-keto Cholesterol
- Packaging1mg
- Price$305
- Updated2026-06-03
- Buy
- ManufacturerUsbiological
- Product number437396
- Product description5alpha-hydroxy-6-keto Cholesterol
- Packaging2.5mg
- Price$432
- Updated2026-06-03
- Buy
| Manufacturer | Product number | Product description | Packaging | Price | Updated | Buy |
|---|---|---|---|---|---|---|
| aablocks | AA000U4U | 5α-hydroxy-6-keto Cholesterol ≥98% | 5mg | $160 | 2026-05-25 | Buy |
| aablocks | AA000U4U | 5α-hydroxy-6-keto Cholesterol ≥98% | 10mg | $303 | 2026-05-25 | Buy |
| AK Scientific | 1446AH | 5alpha-Cholestan-3beta,5alpha-diol-6-one | 1mg | $133 | 2021-12-16 | Buy |
| AK Scientific | 1446AH | 5alpha-Cholestan-3beta,5alpha-diol-6-one | 10mg | $403 | 2021-12-16 | Buy |
| Cayman Chemical | 10007601 | 5α-hydroxy-6-keto Cholesterol ≥98% | 5mg | $160 | 2026-04-30 | Buy |
| Cayman Chemical | 10007601 | 5α-hydroxy-6-keto Cholesterol ≥98% | 1mg | $36 | 2026-04-30 | Buy |
| Cayman Chemical | 10007601 | 5α-hydroxy-6-keto Cholesterol ≥98% | 10mg | $303 | 2026-04-30 | Buy |
| ChemScene | CS-0082542 | 5α-Hydroxy-6-keto cholesterol 99.9% | 5mg | $369 | 2026-06-04 | Buy |
| TRC | C432525 | 5α-hydroxy-6-ketoCholesterol | 1mg | $45 | 2021-12-16 | Buy |
| TRC | C432525 | 5α-hydroxy-6-ketoCholesterol | 2.5mg | $90 | 2021-12-16 | Buy |
| Usbiological | 437396 | 5alpha-hydroxy-6-keto Cholesterol | 1mg | $305 | 2026-06-03 | Buy |
| Usbiological | 437396 | 5alpha-hydroxy-6-keto Cholesterol | 2.5mg | $432 | 2026-06-03 | Buy |
Properties
Melting point :234 °C
Boiling point :528.9±45.0 °C(Predicted)
Density :1.061±0.06 g/cm3(Predicted)
storage temp. :Store at -20°C
solubility :DMF: 20 mg/ml; DMSO: 0.5 mg/ml; Ethanol: 5 mg/ml
form :A crystalline solid
pka :12+-.0.70(Predicted)
color :White to off-white
InChIKey :SJZZRXMQSAXCFD-ZCBMJONGSA-N
SMILES :O[C@]21[C@@]([C@@H]3[C@H]([C@H]4[C@@]([C@H](CC4)[C@@H](CCCC(C)C)C)(CC3)C)CC2=O)(CC[C@@H](C1)O)C
Boiling point :528.9±45.0 °C(Predicted)
Density :1.061±0.06 g/cm3(Predicted)
storage temp. :Store at -20°C
solubility :DMF: 20 mg/ml; DMSO: 0.5 mg/ml; Ethanol: 5 mg/ml
form :A crystalline solid
pka :12+-.0.70(Predicted)
color :White to off-white
InChIKey :SJZZRXMQSAXCFD-ZCBMJONGSA-N
SMILES :O[C@]21[C@@]([C@@H]3[C@H]([C@H]4[C@@]([C@H](CC4)[C@@H](CCCC(C)C)C)(CC3)C)CC2=O)(CC[C@@H](C1)O)C
Safety Information
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Description
5α-hydroxy-6-keto Cholesterol (6-oxo-3,5,-diol) is a major metabolite of cholesterol formed during exposure of lung epithelial cells to ozone, with formation of 5β,6β-epoxycholesterol as a predominant precursor. Exposure of C57BL/6J mice to 0.5-3 ppm ozone produced a dose-dependent formation of 6-oxo-3,5,-diol which was detectable in the bronchalveolar lavage fluid, lavaged cells, and lung homogenates. 6-Oxo-3,5-diol is a potent inhibitor of cholesterol synthesis in human bronchial epithelial cells with an IC50 of 350 nM and exhibits significant cytotoxicity in the low μM range.More related product prices
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