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ChemicalBook >> CAS DataBase List >> 2-[N,N-Bis(trifluoromethanesulfonyl)amino]-5-chloropyridine

2-[N,N-Bis(trifluoromethanesulfonyl)amino]-5-chloropyridine

2-[N,N-Bis(trifluoromethanesulfonyl)amino]-5-chloropyridine price.
  • $5 - $1396.05
  • Product name: 2-[N,N-Bis(trifluoromethanesulfonyl)amino]-5-chloropyridine
  • CAS: 145100-51-2
  • MF: C7H3ClF6N2O4S2
  • MW: 392.68
  • EINECS:629-110-2
  • MDL Number:MFCD00191833
  • Synonyms:Comins Reagent, N,N-Bis(trifluoromethylsulfonyl)-5-chloro-2-pyridylamine, 2-[N,N-Bis(trifluoromethylsulfonyl)amino]-5-chloropyridine;N-(5-CHLORO-2-PYRIDYL)BIS(TRILFUOROMETHANESULFONIMIDE);N-(5-Chloropyridin-2-yl)-1,1,1-trifluoro-N-(trifluoromethylsulfonyl)methanesulfonamide;2-[N,N-Bis(trifluoromethanesulfonyl)amino]-5-chloropyridine ,98%;Comins Triflating Reagent;N-(5-Chloro-2-pyridyl)triflimide N-(5-Chloro-2-pyridyl)bis(trifluoromethanesulfonyl)imide Comins Triflating Reagent;N-(5-chloropyridin-2-yl)-1,1,1-trifluoro-N-(trifluoroMethane)sulfonylMethanesulfonaMide;2-{Bis[(trifluoromethyl)sulphonyl]amino}-5-chloropyridine
Price94 Properties Safety Information Description
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  • Manufactureraablocks
  • Product numberAA001KH7
  • Product description2-[N,N-Bis(trifluoromethanesulfonyl)amino]-5-chloropyridine 98%
  • Packaging1g
  • Price$5
  • Updated2026-05-28
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  • Manufactureraablocks
  • Product numberAA001KH7
  • Product description2-[N,N-Bis(trifluoromethanesulfonyl)amino]-5-chloropyridine 98%
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  • Updated2026-05-28
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  • Manufactureraablocks
  • Product numberAA001KH7
  • Product description2-[N,N-Bis(trifluoromethanesulfonyl)amino]-5-chloropyridine 98%
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  • Updated2026-05-28
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  • Manufactureraablocks
  • Product numberAA001KH7
  • Product description2-[N,N-Bis(trifluoromethanesulfonyl)amino]-5-chloropyridine 98%
  • Packaging25g
  • Price$22
  • Updated2026-05-28
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  • Manufactureraablocks
  • Product numberAA001KH7
  • Product description2-[N,N-Bis(trifluoromethanesulfonyl)amino]-5-chloropyridine 98%
  • Packaging50g
  • Price$43
  • Updated2026-05-28
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  • Manufactureraablocks
  • Product numberAA001KH7
  • Product description2-[N,N-Bis(trifluoromethanesulfonyl)amino]-5-chloropyridine 98%
  • Packaging100g
  • Price$85
  • Updated2026-05-28
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  • ManufacturerAHH
  • Product numberMT-19440
  • Product description2-[N,N-Bis(trifluoromethylsulphonyl)amino]-5chloropyridine 97%
  • Packaging50g
  • Price$325
  • Updated2026-05-26
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  • ManufacturerAK Scientific
  • Product numberW3168
  • Product description2-[N,N-Bis(Trifluoromethylsulphonyl)amino]-5-chloropyridine 99%
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  • Price$233
  • Updated2026-06-04
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  • ManufacturerAK Scientific
  • Product numberJ98921
  • Product description2-[N,N-Bis(Trifluoromethylsulphonyl)amino]-5-chloropyridine 95%
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  • Price$167
  • Updated2026-06-04
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  • ManufacturerAK Scientific
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  • Product description2-[N,N-Bis(Trifluoromethylsulphonyl)amino]-5-chloropyridine 95%
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  • Price$43
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  • ManufacturerAK Scientific
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  • Product description2-[N,N-Bis(Trifluoromethylsulphonyl)amino]-5-chloropyridine 99%
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  • ManufacturerAK Scientific
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  • Price$23
  • Updated2026-06-04
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  • ManufacturerAK Scientific
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  • Product description2-[N,N-Bis(Trifluoromethylsulphonyl)amino]-5-chloropyridine 99%
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  • Price$16
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  • ManufacturerAK Scientific
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  • Product description2-[N,N-Bis(Trifluoromethylsulphonyl)amino]-5-chloropyridine 95%
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  • Price$17
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  • ManufacturerAK Scientific
  • Product numberJ98921
  • Product description2-[N,N-Bis(Trifluoromethylsulphonyl)amino]-5-chloropyridine 95%
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  • Price$12
  • Updated2026-06-04
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  • ManufacturerAK Scientific
  • Product numberJ98921
  • Product description2-[N,N-Bis(Trifluoromethylsulphonyl)amino]-5-chloropyridine
  • Packaging500g
  • Price$1090
  • Updated2021-12-16
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Manufacturer Product number Product description Packaging Price Updated Buy
aablocks AA001KH7 2-[N,N-Bis(trifluoromethanesulfonyl)amino]-5-chloropyridine 98% 1g $5 2026-05-28 Buy
aablocks AA001KH7 2-[N,N-Bis(trifluoromethanesulfonyl)amino]-5-chloropyridine 98% 5g $10 2026-05-28 Buy
aablocks AA001KH7 2-[N,N-Bis(trifluoromethanesulfonyl)amino]-5-chloropyridine 98% 10g $14 2026-05-28 Buy
aablocks AA001KH7 2-[N,N-Bis(trifluoromethanesulfonyl)amino]-5-chloropyridine 98% 25g $22 2026-05-28 Buy
aablocks AA001KH7 2-[N,N-Bis(trifluoromethanesulfonyl)amino]-5-chloropyridine 98% 50g $43 2026-05-28 Buy
aablocks AA001KH7 2-[N,N-Bis(trifluoromethanesulfonyl)amino]-5-chloropyridine 98% 100g $85 2026-05-28 Buy
AHH MT-19440 2-[N,N-Bis(trifluoromethylsulphonyl)amino]-5chloropyridine 97% 50g $325 2026-05-26 Buy
AK Scientific W3168 2-[N,N-Bis(Trifluoromethylsulphonyl)amino]-5-chloropyridine 99% 100g $233 2026-06-04 Buy
AK Scientific J98921 2-[N,N-Bis(Trifluoromethylsulphonyl)amino]-5-chloropyridine 95% 100g $167 2026-06-04 Buy
AK Scientific J98921 2-[N,N-Bis(Trifluoromethylsulphonyl)amino]-5-chloropyridine 95% 25g $43 2026-06-04 Buy
AK Scientific W3168 2-[N,N-Bis(Trifluoromethylsulphonyl)amino]-5-chloropyridine 99% 25g $60 2026-06-04 Buy
AK Scientific W3168 2-[N,N-Bis(Trifluoromethylsulphonyl)amino]-5-chloropyridine 99% 5g $23 2026-06-04 Buy
AK Scientific W3168 2-[N,N-Bis(Trifluoromethylsulphonyl)amino]-5-chloropyridine 99% 1g $16 2026-06-04 Buy
AK Scientific J98921 2-[N,N-Bis(Trifluoromethylsulphonyl)amino]-5-chloropyridine 95% 5g $17 2026-06-04 Buy
AK Scientific J98921 2-[N,N-Bis(Trifluoromethylsulphonyl)amino]-5-chloropyridine 95% 1g $12 2026-06-04 Buy
AK Scientific J98921 2-[N,N-Bis(Trifluoromethylsulphonyl)amino]-5-chloropyridine 500g $1090 2021-12-16 Buy
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Properties

Melting point :45-47 °C(lit.)
Boiling point :77-90°C/0.2mmHg
Density :1.892±0.06 g/cm3(Predicted)
storage temp. :2-8°C
solubility :Benzene (Slightly)
form :Solid
pka :-7.71±0.10(Predicted)
color :yellow
Water Solubility :Reacts with water.
Sensitive :Moisture Sensitive
BRN :5833971
Stability :Moisture Sensitive, Unstable in DMSO Solution
InChI :InChI=1S/C7H3ClF6N2O4S2/c8-4-1-2-5(15-3-4)16(21(17,18)6(9,10)11)22(19,20)7(12,13)14/h1-3H
InChIKey :TUFGVZMNGTYAQD-UHFFFAOYSA-N
SMILES :C(F)(F)(F)S(N(C1=NC=C(Cl)C=C1)S(C(F)(F)F)(=O)=O)(=O)=O
CAS DataBase Reference :145100-51-2(CAS DataBase Reference)

Safety Information

Symbol(GHS): Exclamation Mark (GHS07)
Signal word: Warning
Hazard statements:
Code Hazard statements Hazard class Category Signal word Pictogram P-Codes
H315 Causes skin irritation Skin corrosion/irritation Category 2 Warning P264, P280, P302+P352, P321,P332+P313, P362
H319 Causes serious eye irritation Serious eye damage/eye irritation Category 2A Warning P264, P280, P305+P351+P338,P337+P313P
H335 May cause respiratory irritation Specific target organ toxicity, single exposure;Respiratory tract irritation Category 3 Warning
Precautionary statements:
P261 Avoid breathing dust/fume/gas/mist/vapours/spray.
P264 Wash hands thoroughly after handling.
P264 Wash skin thouroughly after handling.
P271 Use only outdoors or in a well-ventilated area.
P280 Wear protective gloves/protective clothing/eye protection/face protection.
P302+P352 IF ON SKIN: wash with plenty of soap and water.
P305+P351+P338 IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continuerinsing.

Description

2-[N,N-Bis(trifluoromethylsulfonyl)amino]-5-chloropyridine provides good yields of vinyl triflates from the corresponding ketone enolates or dienolates. It is used in the total synthesis of (-)-porantheridine and the trans decahydroquinoline alkaloid (+)-219A. It is also used as a reactant for Suzuki-Miyaura cross coupling, synthesis of nicotinic acetylcholine receptor-selective ligands, enantioselective desymmetrizing palladium catalyzed carbonylation reactions, synthesis of high affinity niacin receptor GPR109A agonists and in preparation of heteroaromatics.

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773-64-8 TRIFLUOROMETHANESULFONIMIDE TRIFLUOROMETHANESULFONAMIDE 2-Amino-5-chloropyridine 145100-51-2 145100-50-1

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Suppliers and manufacturers

Beijing Ouhe Technology Co., Ltd Ningbo Zeyu Chemical Technology Co., Ltd J & K SCIENTIFIC LTD. Meryer (Shanghai) Chemical Technology Co., Ltd. Alfa Aesar TCI (Shanghai) Development Co., Ltd. Energy Chemical Wuhan Chemwish Technology Co., Ltd Capot Chemical Co., Ltd Jia Xing Isenchem Co.,Ltd