4-O-[2-(2,5-dioxopyrrolidin-1-yl)ethyl] 1-O-methyl (E)-but-2-enedioate
![4-O-[2-(2,5-dioxopyrrolidin-1-yl)ethyl] 1-O-methyl (E)-but-2-enedioate price.](/CAS/20180713/GIF/1577222-14-0.gif)
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- $81 - $1620
- Product name: 4-O-[2-(2,5-dioxopyrrolidin-1-yl)ethyl] 1-O-methyl (E)-but-2-enedioate
- CAS: 1577222-14-0
- MF: C11H13NO6
- MW: 255.22
- EINECS:-0
- MDL Number:MFCD28502263
- Synonyms:(2E)-2-Butenedioic acid 1-[2-(2,5-dioxo-1-pyrrolidinyl)ethyl] 4-methyl ester;2-(2,5-Dioxopyrrolidin-1-yl)ethyl methyl fumarate;Diroximel Fumarete;2-(2,5-Dioxopyrrolidin-1-Yl)Ethyl Methyl Fumarate(WXC04774);4-O-[2-(2,5-dioxopyrrolidin-1-yl)ethyl] 1-O-methyl (E)-but-2-enedioate;ALKS-8700;diroximel fumarate;(E)-but-2-enedioic acid 2-(2,5-dioxo-pyrrolidin-1-yl)ethyl ester methyl ester
8 prices
Selected condition：
Brand
- AK Scientific
- Cayman Chemical
- DC Chemicals
Package
- 5mg
- 10mg
- 25mg
- 50mg
- 100mg
- 250mg
- 1g
- ManufacturerAK Scientific
- Product number6016DW
- Product descriptionDiroximelfumarate
- Packaging50mg
- Price$714
- Updated2021-12-16
- Buy
- ManufacturerCayman Chemical
- Product number29111
- Product descriptionDiroximel Fumarate
- Packaging5mg
- Price$81
- Updated2024-03-01
- Buy
- ManufacturerCayman Chemical
- Product number29111
- Product descriptionDiroximel Fumarate
- Packaging10mg
- Price$143
- Updated2024-03-01
- Buy
- ManufacturerCayman Chemical
- Product number29111
- Product descriptionDiroximel Fumarate
- Packaging25mg
- Price$336
- Updated2024-03-01
- Buy
- ManufacturerCayman Chemical
- Product number29111
- Product descriptionDiroximel Fumarate
- Packaging50mg
- Price$553
- Updated2024-03-01
- Buy
- ManufacturerDC Chemicals
- Product numberDC10582
- Product descriptionDiroximelFumarete(ALKS-8700) >98%
- Packaging100mg
- Price$450
- Updated2021-12-16
- Buy
- ManufacturerDC Chemicals
- Product numberDC10582
- Product descriptionDiroximelFumarete(ALKS-8700) >98%
- Packaging250mg
- Price$810
- Updated2021-12-16
- Buy
- ManufacturerDC Chemicals
- Product numberDC10582
- Product descriptionDiroximelFumarete(ALKS-8700) >98%
- Packaging1g
- Price$1620
- Updated2021-12-16
- Buy
| Manufacturer | Product number | Product description | Packaging | Price | Updated | Buy |
|---|---|---|---|---|---|---|
| AK Scientific | 6016DW | Diroximelfumarate | 50mg | $714 | 2021-12-16 | Buy |
| Cayman Chemical | 29111 | Diroximel Fumarate | 5mg | $81 | 2024-03-01 | Buy |
| Cayman Chemical | 29111 | Diroximel Fumarate | 10mg | $143 | 2024-03-01 | Buy |
| Cayman Chemical | 29111 | Diroximel Fumarate | 25mg | $336 | 2024-03-01 | Buy |
| Cayman Chemical | 29111 | Diroximel Fumarate | 50mg | $553 | 2024-03-01 | Buy |
| DC Chemicals | DC10582 | DiroximelFumarete(ALKS-8700) >98% | 100mg | $450 | 2021-12-16 | Buy |
| DC Chemicals | DC10582 | DiroximelFumarete(ALKS-8700) >98% | 250mg | $810 | 2021-12-16 | Buy |
| DC Chemicals | DC10582 | DiroximelFumarete(ALKS-8700) >98% | 1g | $1620 | 2021-12-16 | Buy |
Properties
Melting point :96 - 99°C
Boiling point :441.0±25.0 °C(Predicted)
Density :1.319±0.06 g/cm3(Predicted)
storage temp. :-20°C Freezer, Under inert atmosphere
solubility :DMSO (Slightly), Ethyl Acetate (Slightly)
form :Solid
pka :-1.60±0.20(Predicted)
color :White to Off-White
InChI :InChI=1S/C11H13NO6/c1-17-10(15)4-5-11(16)18-7-6-12-8(13)2-3-9(12)14/h4-5H,2-3,6-7H2,1H3/b5-4+
InChIKey :YIMYDTCOUQIDMT-SNAWJCMRSA-N
SMILES :C(OCCN1C(=O)CCC1=O)(=O)/C=C/C(OC)=O
Boiling point :441.0±25.0 °C(Predicted)
Density :1.319±0.06 g/cm3(Predicted)
storage temp. :-20°C Freezer, Under inert atmosphere
solubility :DMSO (Slightly), Ethyl Acetate (Slightly)
form :Solid
pka :-1.60±0.20(Predicted)
color :White to Off-White
InChI :InChI=1S/C11H13NO6/c1-17-10(15)4-5-11(16)18-7-6-12-8(13)2-3-9(12)14/h4-5H,2-3,6-7H2,1H3/b5-4+
InChIKey :YIMYDTCOUQIDMT-SNAWJCMRSA-N
SMILES :C(OCCN1C(=O)CCC1=O)(=O)/C=C/C(OC)=O
Safety Information
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Description
Diroximel fumarate is a prodrug form of monomethyl fumarate . It undergoes esterase cleavage in the gut to release monomethyl fumarate. Formulations containing diroximel fumarate have been used in the treatment of relapsing-remitting multiple sclerosis.More related product prices
1-MethylpyrrolidineRelated product price
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$8-1225
![4-O-[2-(2,5-dioxopyrrolidin-1-yl)ethyl] 1-O-methyl (E)-but-2-enedioate](https://img.chemicalbook.com/ProductImageEN/2020-10/small/592b448a-abae-4688-9744-3dd819d91270.png){kind=small}