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ChemicalBook >> CAS DataBase List >> tert-butyl 2-((1H-pyrrolo[2,3-b]pyridin-5-yl)oxy)-4-bromobenzoate

tert-butyl 2-((1H-pyrrolo[2,3-b]pyridin-5-yl)oxy)-4-bromobenzoate

tert-butyl 2-((1H-pyrrolo[2,3-b]pyridin-5-yl)oxy)-4-bromobenzoate price.
  • $53 - $708.75
  • Product name: tert-butyl 2-((1H-pyrrolo[2,3-b]pyridin-5-yl)oxy)-4-bromobenzoate
  • CAS: 1628047-84-6
  • MF: C18H17BrN2O3
  • MW: 389.24
  • EINECS:942-459-8
  • MDL Number:MFCD28334265
  • Synonyms:tert-butyl 2-((1H-pyrrolo[2,3-b]pyridin-5-yl)oxy)-4-bromobenzoate;tert-butyl 4-bromo-2-{1H-pyrrolo[2,3-b]pyridin-5-yloxy}benzoate;ABT199 intermediate 2;4-Bromo-2-(1H-pyrrolo[2,3-b]pyridin-5-yloxy)benzoic acid 1,1-dimethylethyl ester;2575SM2;Benzoic acid, 4-bromo-2-(1H-pyrrolo[2,3-b]pyridin-5-yloxy)-, 1,1-dimethylethyl ester;2-Methyl-2-propanyl 4-bromo-2-(1H-pyrrolo[2,3-b]pyridin-5-yloxy)benzoate;Tert-butyl 4-bromo-2-{1H-pyrrolo[2,3-b]pyridine -5- yloxy}benzoate
Price9 Properties Safety Information Description
9 prices
Selected condition：
Brand
  • Alichem
  • Chemenu
  • ChemScene
  • Crysdot
  • TRC
Package
  • 1g
  • 5g
  • 10g
  • 25g
  • ManufacturerAlichem
  • Product number1628047846
  • Product descriptiontert-Butyl2-((1H-pyrrolo[2,3-b]pyridin-5-yl)oxy)-4-bromobenzoate
  • Packaging25g
  • Price$708.75
  • Updated2021-12-16
  • Buy
  • ManufacturerChemenu
  • Product numberCM105014
  • Product descriptiontert-butyl4-bromo-2-{1H-pyrrolo[2,3-b]pyridin-5-yloxy}benzoate 95%+
  • Packaging1g
  • Price$53
  • Updated2021-12-16
  • Buy
  • ManufacturerChemenu
  • Product numberCM105014
  • Product descriptiontert-butyl4-bromo-2-{1H-pyrrolo[2,3-b]pyridin-5-yloxy}benzoate 95%+
  • Packaging5g
  • Price$141
  • Updated2021-12-16
  • Buy
  • ManufacturerChemenu
  • Product numberCM105014
  • Product descriptiontert-butyl4-bromo-2-{1H-pyrrolo[2,3-b]pyridin-5-yloxy}benzoate 95%+
  • Packaging10g
  • Price$268
  • Updated2021-12-16
  • Buy
  • ManufacturerChemScene
  • Product numberCS-B1514
  • Product descriptiontert-Butyl2-((1H-pyrrolo[2,3-b]pyridin-5-yl)oxy)-4-bromobenzoate
  • Packaging5g
  • Price$95
  • Updated2021-12-16
  • Buy
  • ManufacturerChemScene
  • Product numberCS-B1514
  • Product descriptiontert-Butyl2-((1H-pyrrolo[2,3-b]pyridin-5-yl)oxy)-4-bromobenzoate
  • Packaging10g
  • Price$178
  • Updated2021-12-16
  • Buy
  • ManufacturerCrysdot
  • Product numberCD11242995
  • Product descriptiontert-Butyl2-((1H-pyrrolo[2,3-b]pyridin-5-yl)oxy)-4-bromobenzoate 97%
  • Packaging5g
  • Price$150
  • Updated2021-12-16
  • Buy
  • ManufacturerCrysdot
  • Product numberCD11242995
  • Product descriptiontert-Butyl2-((1H-pyrrolo[2,3-b]pyridin-5-yl)oxy)-4-bromobenzoate 97%
  • Packaging10g
  • Price$295
  • Updated2021-12-16
  • Buy
  • ManufacturerTRC
  • Product numberB694160
  • Product descriptiontert-​Butyl4-​Bromo-​2-​(1H-​pyrrolo[2,​3-​b]​pyridin-​5-​yloxy)benzoate
  • Packaging5g
  • Price$495
  • Updated2021-12-16
  • Buy
Manufacturer Product number Product description Packaging Price Updated Buy
Alichem 1628047846 tert-Butyl2-((1H-pyrrolo[2,3-b]pyridin-5-yl)oxy)-4-bromobenzoate 25g $708.75 2021-12-16 Buy
Chemenu CM105014 tert-butyl4-bromo-2-{1H-pyrrolo[2,3-b]pyridin-5-yloxy}benzoate 95%+ 1g $53 2021-12-16 Buy
Chemenu CM105014 tert-butyl4-bromo-2-{1H-pyrrolo[2,3-b]pyridin-5-yloxy}benzoate 95%+ 5g $141 2021-12-16 Buy
Chemenu CM105014 tert-butyl4-bromo-2-{1H-pyrrolo[2,3-b]pyridin-5-yloxy}benzoate 95%+ 10g $268 2021-12-16 Buy
ChemScene CS-B1514 tert-Butyl2-((1H-pyrrolo[2,3-b]pyridin-5-yl)oxy)-4-bromobenzoate 5g $95 2021-12-16 Buy
ChemScene CS-B1514 tert-Butyl2-((1H-pyrrolo[2,3-b]pyridin-5-yl)oxy)-4-bromobenzoate 10g $178 2021-12-16 Buy
Crysdot CD11242995 tert-Butyl2-((1H-pyrrolo[2,3-b]pyridin-5-yl)oxy)-4-bromobenzoate 97% 5g $150 2021-12-16 Buy
Crysdot CD11242995 tert-Butyl2-((1H-pyrrolo[2,3-b]pyridin-5-yl)oxy)-4-bromobenzoate 97% 10g $295 2021-12-16 Buy
TRC B694160 tert-​Butyl4-​Bromo-​2-​(1H-​pyrrolo[2,​3-​b]​pyridin-​5-​yloxy)benzoate 5g $495 2021-12-16 Buy

Properties

Melting point :188 - 190°C
Density :1.445±0.06 g/cm3(Predicted)
storage temp. :-20°C Freezer, Under inert atmosphere
solubility :Chloroform (Slightly), DMSO (Slightly)
pka :13.26±0.40(Predicted)
form :Solid
color :White to Off-White
InChI :InChI=1S/C18H17BrN2O3/c1-18(2,3)24-17(22)14-5-4-12(19)9-15(14)23-13-8-11-6-7-20-16(11)21-10-13/h4-10H,1-3H3,(H,20,21)
InChIKey :QTUZSJSEZUZNAS-UHFFFAOYSA-N
SMILES :C(OC(C)(C)C)(=O)C1=CC=C(Br)C=C1OC1=CN=C2NC=CC2=C1

Safety Information

Symbol(GHS): GHS hazard pictograms
Signal word: Warning
Hazard statements:
Code Hazard statements Hazard class Category Signal word Pictogram P-Codes
H302 Harmful if swallowed Acute toxicity,oral Category 4 Warning GHS hazard pictograms P264, P270, P301+P312, P330, P501
H315 Causes skin irritation Skin corrosion/irritation Category 2 Warning GHS hazard pictograms P264, P280, P302+P352, P321,P332+P313, P362
H319 Causes serious eye irritation Serious eye damage/eye irritation Category 2A Warning GHS hazard pictograms P264, P280, P305+P351+P338,P337+P313P
H335 May cause respiratory irritation Specific target organ toxicity, single exposure;Respiratory tract irritation Category 3 Warning GHS hazard pictograms
Precautionary statements:
P261 Avoid breathing dust/fume/gas/mist/vapours/spray.
P264 Wash hands thoroughly after handling.
P264 Wash skin thouroughly after handling.
P270 Do not eat, drink or smoke when using this product.
P271 Use only outdoors or in a well-ventilated area.
P280 Wear protective gloves/protective clothing/eye protection/face protection.
P301+P312 IF SWALLOWED: call a POISON CENTER or doctor/physician IF you feel unwell.
P302+P352 IF ON SKIN: wash with plenty of soap and water.
P304+P340 IF INHALED: Remove victim to fresh air and Keep at rest in a position comfortable for breathing.
P305+P351+P338 IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continuerinsing.
P330 Rinse mouth.
P332+P313 IF SKIN irritation occurs: Get medical advice/attention.
P337+P313 IF eye irritation persists: Get medical advice/attention.
P362 Take off contaminated clothing and wash before reuse.
P403+P233 Store in a well-ventilated place. Keep container tightly closed.
P405 Store locked up.
P501 Dispose of contents/container to..…

Description

tert-?Butyl 4-?Bromo-?2-?(1H-?pyrrolo[2,?3-?b]?pyridin-?5-?yloxy)benzoate is used in the synthesis of apoptosis-inducing agents. Intermediate of Venetoclax (A112430), a potent and selective BCL-2 inhibitor that achieves potent antitumour activity while sparing platelets.

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Suppliers and manufacturers

ZHENGZHOU JIUYI TIME NEW MATERIALS CO,.LTD
2-Methyl-2-propanyl 4-bromo-2-(1H-pyrrolo[2,3-b]pyridin-5-yloxy)benzoate
$2.20 /100KG
2-Methyl-2-propanyl 4-bromo-2-(1H-pyrrolo[2,3-b]pyridin-5-yloxy)benzoate CAS:1628047-84-6
career henan chemical co
TERT-BUTYL 2-((1H-PYRROLO[2,3-B]PYRIDIN-5-YL)OXY)-4-BROMOBENZOATE
$3.00 /1KG
TERT-BUTYL 2-((1H-PYRROLO[2,3-B]PYRIDIN-5-YL)OXY)-4-BROMOBENZOATE CAS:1628047-84-6
Shanghai Daken Advanced Materials Co.,Ltd
ATK CHEMICAL COMPANY LIMITED
Nanjing Dolon Biotechnology Co.,Ltd.
Shanghai Yingrui Biopharma Co.,Ltd
Antai Fine Chemical Technology Co.,Limited
Shanghai UCHEM Inc.
Unipharm pharmaceutical industry Co., Ltd
AFINE CHEMICALS LIMITED