1H-INDOLE-5-CARBOXAMIDE, 97%
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- $37 - $2148.3
- Product name: 1H-INDOLE-5-CARBOXAMIDE, 97%
- CAS: 1670-87-7
- MF: C9H8N2O
- MW: 160.17
- EINECS:
- MDL Number:MFCD07779486
- Synonyms:1H-INDOLE-5-CARBOXAMIDE, 97%;SD-169;1H-Indole-5-carboxamide(9CI);5-(AMinocarbonyl)-1H-indole;5-CarbaMoylindole;p38 MAP Kinase Inhibitor VII, SD-169 ;5-(Aminocarbonyl)-1H-indole, 5-Carbamoylindole, 5-Carboxamidoindole;p38 MAP Kinase Inhibitor VII, SD-169 - CAS 1670-87-7 - Calbiochem
43 prices
Selected condition:
Brand
- Adipogen Life Sciences
- AK Scientific
- Ambeed
- American Custom Chemicals Corporation
- ApexBio Technology
- AstaTech
- Axon Medchem
- Cayman Chemical
- Chem-Impex
- ChemScene
- CSNpharm
- Matrix Scientific
- Medical Isotopes, Inc.
- Sigma-Aldrich
- TRC
Package
- 1mg
- 5mg
- 10mg
- 25mg
- 50mg
- 0.1G
- 100mg
- 100.00mg
- 250mg
- 0.25G
- 250.00mg
- 500mg
- 1.00g
- 1g
- 5G
- 10G
- ManufacturerAdipogen Life Sciences
- Product numberSYN-1079-M001
- Product descriptionSD-169 ≥95%
- Packaging1mg
- Price$54
- Updated2026-05-06
- Buy
- ManufacturerAdipogen Life Sciences
- Product numberSYN-1079-M005
- Product descriptionSD-169 ≥95%
- Packaging5mg
- Price$70
- Updated2026-05-06
- Buy
- ManufacturerAdipogen Life Sciences
- Product numberSYN-1079-M010
- Product descriptionSD-169 ≥95%
- Packaging10mg
- Price$81
- Updated2021-12-16
- Buy
- ManufacturerAdipogen Life Sciences
- Product numberSYN-1079-M010
- Product descriptionSD-169 ≥95%
- Packaging10mg
- Price$81
- Updated2026-05-06
- Buy
- ManufacturerAdipogen Life Sciences
- Product numberSYN-1079-M100
- Product descriptionSD-169 ≥95%
- Packaging100mg
- Price$378
- Updated2026-05-06
- Buy
- ManufacturerAdipogen Life Sciences
- Product numberSYN-1079-M050
- Product descriptionSD-169 ≥95%
- Packaging50mg
- Price$259
- Updated2026-05-06
- Buy
- ManufacturerAK Scientific
- Product numberSYN1079
- Product descriptionSD169
- Packaging50mg
- Price$260
- Updated2021-12-16
- Buy
- ManufacturerAmbeed
- Product numberA538658
- Product description1H-indole-5-carboxamide 97%
- Packaging1g
- Price$194
- Updated2021-12-16
- Buy
- ManufacturerAmbeed
- Product numberA538658
- Product description1H-indole-5-carboxamide 97%
- Packaging250mg
- Price$71
- Updated2021-12-16
- Buy
- ManufacturerAmbeed
- Product numberA538658
- Product description1H-indole-5-carboxamide 97%
- Packaging100mg
- Price$46
- Updated2021-12-16
- Buy
- ManufacturerAmerican Custom Chemicals Corporation
- Product numberKIN0000301
- Product description1H-INDOLE-5-CARBOXAMIDE 95.00%
- Packaging1G
- Price$716.1
- Updated2021-12-16
- Buy
- ManufacturerAmerican Custom Chemicals Corporation
- Product numberKIN0000301
- Product description1H-INDOLE-5-CARBOXAMIDE 95.00%
- Packaging1MG
- Price$166.95
- Updated2021-12-16
- Buy
- ManufacturerAmerican Custom Chemicals Corporation
- Product numberKIN0000301
- Product description1H-INDOLE-5-CARBOXAMIDE 95.00%
- Packaging10G
- Price$2148.3
- Updated2021-12-16
- Buy
- ManufacturerApexBio Technology
- Product numberC5850
- Product descriptionSD 169
- Packaging10mg
- Price$50
- Updated2026-05-06
- Buy
- ManufacturerApexBio Technology
- Product numberC5850
- Product descriptionSD169
- Packaging10mg
- Price$68
- Updated2021-12-16
- Buy
- ManufacturerApexBio Technology
- Product numberC5850
- Product descriptionSD 169
- Packaging25mg
- Price$120
- Updated2026-05-06
- Buy
| Manufacturer | Product number | Product description | Packaging | Price | Updated | Buy |
|---|---|---|---|---|---|---|
| Adipogen Life Sciences | SYN-1079-M001 | SD-169 ≥95% | 1mg | $54 | 2026-05-06 | Buy |
| Adipogen Life Sciences | SYN-1079-M005 | SD-169 ≥95% | 5mg | $70 | 2026-05-06 | Buy |
| Adipogen Life Sciences | SYN-1079-M010 | SD-169 ≥95% | 10mg | $81 | 2021-12-16 | Buy |
| Adipogen Life Sciences | SYN-1079-M010 | SD-169 ≥95% | 10mg | $81 | 2026-05-06 | Buy |
| Adipogen Life Sciences | SYN-1079-M100 | SD-169 ≥95% | 100mg | $378 | 2026-05-06 | Buy |
| Adipogen Life Sciences | SYN-1079-M050 | SD-169 ≥95% | 50mg | $259 | 2026-05-06 | Buy |
| AK Scientific | SYN1079 | SD169 | 50mg | $260 | 2021-12-16 | Buy |
| Ambeed | A538658 | 1H-indole-5-carboxamide 97% | 1g | $194 | 2021-12-16 | Buy |
| Ambeed | A538658 | 1H-indole-5-carboxamide 97% | 250mg | $71 | 2021-12-16 | Buy |
| Ambeed | A538658 | 1H-indole-5-carboxamide 97% | 100mg | $46 | 2021-12-16 | Buy |
| American Custom Chemicals Corporation | KIN0000301 | 1H-INDOLE-5-CARBOXAMIDE 95.00% | 1G | $716.1 | 2021-12-16 | Buy |
| American Custom Chemicals Corporation | KIN0000301 | 1H-INDOLE-5-CARBOXAMIDE 95.00% | 1MG | $166.95 | 2021-12-16 | Buy |
| American Custom Chemicals Corporation | KIN0000301 | 1H-INDOLE-5-CARBOXAMIDE 95.00% | 10G | $2148.3 | 2021-12-16 | Buy |
| ApexBio Technology | C5850 | SD 169 | 10mg | $50 | 2026-05-06 | Buy |
| ApexBio Technology | C5850 | SD169 | 10mg | $68 | 2021-12-16 | Buy |
| ApexBio Technology | C5850 | SD 169 | 25mg | $120 | 2026-05-06 | Buy |
Properties
Melting point :159-163 °C
Boiling point :457.6±18.0 °C(Predicted)
Density :1.328±0.06 g/cm3(Predicted)
storage temp. :Sealed in dry,2-8°C
solubility :DMSO (Slightly), Methanol (Slightly)
form :Off-white solid
pka :16.25±0.30(Predicted)
color :Off-White to Light Purple
Water Solubility :water: 1mg/mL
DMSO: 10mg/mL InChI :1S/C9H8N2O/c10-9(12)7-1-2-8-6(5-7)3-4-11-8/h1-5,11H,(H2,10,12)
InChIKey :GQMYQEAXTITUAE-UHFFFAOYSA-N
SMILES :[nH]1c2c(cc1)cc(cc2)C(=O)N
Boiling point :457.6±18.0 °C(Predicted)
Density :1.328±0.06 g/cm3(Predicted)
storage temp. :Sealed in dry,2-8°C
solubility :DMSO (Slightly), Methanol (Slightly)
form :Off-white solid
pka :16.25±0.30(Predicted)
color :Off-White to Light Purple
Water Solubility :water: 1mg/mL
DMSO: 10mg/mL InChI :1S/C9H8N2O/c10-9(12)7-1-2-8-6(5-7)3-4-11-8/h1-5,11H,(H2,10,12)
InChIKey :GQMYQEAXTITUAE-UHFFFAOYSA-N
SMILES :[nH]1c2c(cc1)cc(cc2)C(=O)N
Safety Information
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Description
SD 169 is a selective ATP competitive inhibitor of the MAP kinases p38α (IC50 = 3.2 nM) and p38β (IC50 = 122 nM). It has no inhibitory effect against a panel of other kinases, including p38γ MAP kinase, ERK2, JNK-1, and MAPKAPK-2, when tested in vitro at 50 μM. SD 169 is orally active, significantly reducing p38 MAP kinase expression in T cells of nonobese diabetic mice when delivered in chow at 600 mg/kg. In this model, SD 169 also reduced the incidence of diabetes, lowered blood glucose, and improved glucose homeostasis. SD 169 also enhances axonal regeneration after sciatic nerve crush injury in rats, when given by gavage (30 mg/kg) before and after nerve damage.More related product prices
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