2,3-Bis(bromomethyl)quinoxaline 1,4-dioxide
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- $30 - $1584
- Product name: 2,3-Bis(bromomethyl)quinoxaline 1,4-dioxide
- CAS: 18080-67-6
- MF: C10H8Br2N2O2
- MW: 347.99
- EINECS:
- MDL Number:MFCD00186742
- Synonyms:2,3-bis(broMoMethyl)-1-oxoquinoxalin-1-iuM-4(1H)-olate;Conoidin A;Quinoxaline, 2,3-bis(bromomethyl)-, 1,4-dioxide;antioxidative,antioxidant,heart disease,Parasite,Inhibitor,Peroxiredoxin II,hyperperoxidation,Conoidin A,ischaemic,inhibit,neuroprotective;Conoidin A, 10 mM in DMSO;Peroxiredoxin Inhibitor, Conoidin A;1,4-Dioxo-2,3-dibromomethylquinoline;2,3-Bis(bromomethyl)quinoxaline 1,4-dioxide
31 prices
Selected condition：
Brand
- aablocks
- ACHEMBLOCK
- AK Scientific
- Alichem
- American Custom Chemicals Corporation
- ApexBio Technology
- Axon Medchem
- Cayman Chemical
- Chemenu
- ChemScene
- DC Chemicals
- Sigma-Aldrich
- TRC
Package
- 2mg
- 5mg
- 10mg
- 25mg
- 50mg
- 100mg
- 250mg
- 1g
- 5g
- 25g
- Manufactureraablocks
- Product numberAA0022AT
- Product description2,3-Bis(Bromomethyl)Quinoxaline 1,4-Dioxide ≥96%
- Packaging2mg
- Price$30
- Updated2026-05-28
- Buy
- Manufactureraablocks
- Product numberAA0022AT
- Product description2,3-Bis(Bromomethyl)Quinoxaline 1,4-Dioxide ≥96%
- Packaging5mg
- Price$40
- Updated2026-05-28
- Buy
- Manufactureraablocks
- Product numberAA0022AT
- Product description2,3-Bis(Bromomethyl)Quinoxaline 1,4-Dioxide ≥96%
- Packaging10mg
- Price$54
- Updated2026-05-28
- Buy
- Manufactureraablocks
- Product numberAA0022AT
- Product description2,3-Bis(Bromomethyl)Quinoxaline 1,4-Dioxide ≥95%
- Packaging25mg
- Price$63
- Updated2026-05-28
- Buy
- Manufactureraablocks
- Product numberAA0022AT
- Product description2,3-Bis(Bromomethyl)Quinoxaline 1,4-Dioxide ≥95%
- Packaging50mg
- Price$94
- Updated2026-05-28
- Buy
- Manufactureraablocks
- Product numberAA0022AT
- Product description2,3-Bis(Bromomethyl)Quinoxaline 1,4-Dioxide ≥95%
- Packaging100mg
- Price$123
- Updated2026-05-28
- Buy
- Manufactureraablocks
- Product numberAA0022AT
- Product description2,3-Bis(Bromomethyl)Quinoxaline 1,4-Dioxide ≥95%
- Packaging250mg
- Price$274
- Updated2026-05-28
- Buy
- ManufacturerACHEMBLOCK
- Product numberZ238455
- Product descriptionConoidin A 98%
- Packaging250MG
- Price$200
- Updated2026-05-27
- Buy
- ManufacturerACHEMBLOCK
- Product numberZ238455
- Product descriptionConoidin A 98%
- Packaging100MG
- Price$100
- Updated2026-05-27
- Buy
- ManufacturerAK Scientific
- Product number9480AA
- Product description2,3-Bis(bromomethyl)quinoxaline1,4-dioxide
- Packaging25mg
- Price$160
- Updated2021-12-16
- Buy
- ManufacturerAlichem
- Product number18080676
- Product description2,3-Bis(Bromomethyl)-1-oxoquinoxalin-1-ium-4(1h)-olate
- Packaging5g
- Price$538.56
- Updated2021-12-16
- Buy
- ManufacturerAlichem
- Product number18080676
- Product description2,3-Bis(Bromomethyl)-1-oxoquinoxalin-1-ium-4(1h)-olate
- Packaging25g
- Price$1584
- Updated2021-12-16
- Buy
- ManufacturerAmerican Custom Chemicals Corporation
- Product numberHCH0362526
- Product description2,3-BIS(BROMOMETHYL)QUINOXALINE 1,4-DIOXIDE 95.00%
- Packaging5MG
- Price$496.98
- Updated2021-12-16
- Buy
- ManufacturerApexBio Technology
- Product numberC4293
- Product descriptionConoidin A
- Packaging250mg
- Price$420
- Updated2026-05-06
- Buy
- ManufacturerApexBio Technology
- Product numberC4293
- Product descriptionConoidin A
- Packaging100mg
- Price$216
- Updated2026-05-06
- Buy
- ManufacturerApexBio Technology
- Product numberC4293
- Product descriptionConoidin A
- Packaging50mg
- Price$168
- Updated2026-05-06
- Buy
| Manufacturer | Product number | Product description | Packaging | Price | Updated | Buy |
|---|---|---|---|---|---|---|
| aablocks | AA0022AT | 2,3-Bis(Bromomethyl)Quinoxaline 1,4-Dioxide ≥96% | 2mg | $30 | 2026-05-28 | Buy |
| aablocks | AA0022AT | 2,3-Bis(Bromomethyl)Quinoxaline 1,4-Dioxide ≥96% | 5mg | $40 | 2026-05-28 | Buy |
| aablocks | AA0022AT | 2,3-Bis(Bromomethyl)Quinoxaline 1,4-Dioxide ≥96% | 10mg | $54 | 2026-05-28 | Buy |
| aablocks | AA0022AT | 2,3-Bis(Bromomethyl)Quinoxaline 1,4-Dioxide ≥95% | 25mg | $63 | 2026-05-28 | Buy |
| aablocks | AA0022AT | 2,3-Bis(Bromomethyl)Quinoxaline 1,4-Dioxide ≥95% | 50mg | $94 | 2026-05-28 | Buy |
| aablocks | AA0022AT | 2,3-Bis(Bromomethyl)Quinoxaline 1,4-Dioxide ≥95% | 100mg | $123 | 2026-05-28 | Buy |
| aablocks | AA0022AT | 2,3-Bis(Bromomethyl)Quinoxaline 1,4-Dioxide ≥95% | 250mg | $274 | 2026-05-28 | Buy |
| ACHEMBLOCK | Z238455 | Conoidin A 98% | 250MG | $200 | 2026-05-27 | Buy |
| ACHEMBLOCK | Z238455 | Conoidin A 98% | 100MG | $100 | 2026-05-27 | Buy |
| AK Scientific | 9480AA | 2,3-Bis(bromomethyl)quinoxaline1,4-dioxide | 25mg | $160 | 2021-12-16 | Buy |
| Alichem | 18080676 | 2,3-Bis(Bromomethyl)-1-oxoquinoxalin-1-ium-4(1h)-olate | 5g | $538.56 | 2021-12-16 | Buy |
| Alichem | 18080676 | 2,3-Bis(Bromomethyl)-1-oxoquinoxalin-1-ium-4(1h)-olate | 25g | $1584 | 2021-12-16 | Buy |
| American Custom Chemicals Corporation | HCH0362526 | 2,3-BIS(BROMOMETHYL)QUINOXALINE 1,4-DIOXIDE 95.00% | 5MG | $496.98 | 2021-12-16 | Buy |
| ApexBio Technology | C4293 | Conoidin A | 250mg | $420 | 2026-05-06 | Buy |
| ApexBio Technology | C4293 | Conoidin A | 100mg | $216 | 2026-05-06 | Buy |
| ApexBio Technology | C4293 | Conoidin A | 50mg | $168 | 2026-05-06 | Buy |
Properties
Melting point :180-190 °C (decomp)
Boiling point :512.3±60.0 °C(Predicted)
Density :1.95±0.1 g/cm3(Predicted)
storage temp. :-20°C
solubility :DMF: 25 mg/ml; DMF:PBS(pH 7.2)(1:1): 0.5 mg/ml; DMSO: 20 mg/ml
form :A crystalline solid
pka :1.91±0.30(Predicted)
color :White to yellow
InChI :1S/C10H8Br2N2O2/c11-5-9-10(6-12)14(16)8-4-2-1-3-7(8)13(9)15/h1-4H,5-6H2
InChIKey :DQKNFTLRMZOAMG-UHFFFAOYSA-N
SMILES :BrCC1=C(N(c2c(cccc2)[N+]1=O)[O-])CBr
Boiling point :512.3±60.0 °C(Predicted)
Density :1.95±0.1 g/cm3(Predicted)
storage temp. :-20°C
solubility :DMF: 25 mg/ml; DMF:PBS(pH 7.2)(1:1): 0.5 mg/ml; DMSO: 20 mg/ml
form :A crystalline solid
pka :1.91±0.30(Predicted)
color :White to yellow
InChI :1S/C10H8Br2N2O2/c11-5-9-10(6-12)14(16)8-4-2-1-3-7(8)13(9)15/h1-4H,5-6H2
InChIKey :DQKNFTLRMZOAMG-UHFFFAOYSA-N
SMILES :BrCC1=C(N(c2c(cccc2)[N+]1=O)[O-])CBr
Safety Information
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Description
Peroxiredoxins are a widely conserved family of enzymes that function in antioxidant defense and act in redox signaling pathways. Increased expression of human peroxiredoxin is associated with cancer, cardiovascular dysfunction, and neurodegeneration. Conoidin A inactivates peroxiredoxins by covalently binding to the catalytic cysteine on the enzyme. It has been shown to inhibit peroxiredoxin II (IC50 = 23 μM) in the parasite T. gondii and peroxiredoxin I in the hookworm A. ceylanicum. At 5 μM, conoidin A can also inhibit the glucose oxidase-mediated hyperoxidation of mammalian peroxiredoxin I and II, but not peroxiredoxin III.Related product price
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