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ChemicalBook >> CAS DataBase List >>2,3-Bis(bromomethyl)quinoxaline 1,4-dioxide

2,3-Bis(bromomethyl)quinoxaline 1,4-dioxide

2,3-Bis(bromomethyl)quinoxaline 1,4-dioxide Structure
2,3-Bis(bromomethyl)quinoxaline 1,4-dioxide structure
CAS No.
18080-67-6
Chemical Name:
2,3-Bis(bromomethyl)quinoxaline 1,4-dioxide
Synonyms
Conoidin A;Conoidin A, 10 mM in DMSO;Peroxiredoxin Inhibitor, Conoidin A;1,4-Dioxo-2,3-dibromomethylquinoline;2,3-Bis(bromomethyl)quinoxaline 1,4-dioxide;Quinoxaline, 2,3-bis(bromomethyl)-, 1,4-dioxide;2,3-bis(broMoMethyl)-1-oxoquinoxalin-1-iuM-4(1H)-olate;antioxidative,antioxidant,heart disease,Parasite,Inhibitor,Peroxiredoxin II,hyperperoxidation,Conoidin A,ischaemic,inhibit,neuroprotective
CBNumber:
CB72455090
Molecular Formula:
C10H8Br2N2O2
Molecular Weight:
347.99
MDL Number:
MFCD00186742
MOL File:
18080-67-6.mol
MSDS File:
SDS
TDS File:
TDS
Last updated:2026-09-12 18:54:50
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2,3-Bis(bromomethyl)quinoxaline 1,4-dioxide Properties

Melting point 180-190 °C (decomp)
Boiling point 512.3±60.0 °C(Predicted)
Density 1.95±0.1 g/cm3(Predicted)
storage temp. -20°C
solubility DMF: 25 mg/ml; DMF:PBS(pH 7.2)(1:1): 0.5 mg/ml; DMSO: 20 mg/ml
form A crystalline solid
pka 1.91±0.30(Predicted)
color White to yellow
InChI 1S/C10H8Br2N2O2/c11-5-9-10(6-12)14(16)8-4-2-1-3-7(8)13(9)15/h1-4H,5-6H2
InChIKey DQKNFTLRMZOAMG-UHFFFAOYSA-N
SMILES BrCC1=C(N(c2c(cccc2)[N+]1=O)[O-])CBr
UNSPSC Code 12352200
NACRES NA.77

SAFETY

Risk and Safety Statements

Hazard statements  H413
Precautionary statements  P273-P501
WGK Germany  WGK 3
Storage Class 11 - Combustible Solids
Hazard Classifications Aquatic Chronic 4

2,3-Bis(bromomethyl)quinoxaline 1,4-dioxide price More Price(31)

Manufacturer Product number Product description CAS number Packaging Price Updated Buy
Sigma-Aldrich 5.30746 Peroxiredoxin Inhibitor, Conoidin A - CAS 18080-67-6 - Calbiochem 18080-67-6 25mg $291 2026-04-30 Buy
Cayman Chemical 15605 Conoidin A ≥95% 18080-67-6 25mg $63 2026-04-30 Buy
Cayman Chemical 15605 Conoidin A ≥95% 18080-67-6 50mg $94 2026-04-30 Buy
Cayman Chemical 15605 Conoidin A ≥95% 18080-67-6 100mg $123 2026-04-30 Buy
Cayman Chemical 15605 Conoidin A ≥95% 18080-67-6 250mg $274 2026-04-30 Buy
Product number Packaging Price Buy
5.30746 25mg $291 Buy
15605 25mg $63 Buy
15605 50mg $94 Buy
15605 100mg $123 Buy
15605 250mg $274 Buy

2,3-Bis(bromomethyl)quinoxaline 1,4-dioxide Chemical Properties, Uses, Production

Uses

Conoidin A is a peroxiredoxin inhibitor.

Biological Activity

Cell permeable: yes', 'Primary Target
Peroxiredoxin', 'Reversible: no', 'Target IC50: 23 μM for blocking TgPrxII hyperperoxidation activity

in vivo

Conoidin A (intraperitoneal injection; 5 mg/kg; for three successive days before MI/R injury) blocks the effect of Luteolin (HY-N0162) on the ST-segment elevation. Furthermore, an increase in the infarct size presented of the MI/R group can be reduced by Luteolin. But pre-treatment with conoidin A abolishs the effect of Luteolin. Pre-treatment with conoidin A also prevents Luteolin-reduced activities of CK-MB, AST and LDH in vivo[3].

Animal Model:Rat myocardial I/R model[3]
Dosage:5mg/kg
Administration:Intraperitoneal injection; 5mg/kg; for three successive days before MI/R injury
Result:Significantly reversed the antioxidative effect of Luteolin. Impaired the protective effects of luteolin.

IC 50

Toxoplasma

2,3-Bis(bromomethyl)quinoxaline 1,4-dioxide Preparation Products And Raw materials

Raw materials

Preparation Products

2,3-Bis(bromomethyl)quinoxaline 1,4-dioxide Suppliers

Global Suppliers ( 82)
Supplier Tel Email Country ProdList Advantage
Candia Thamtech Company Limited 0371-86615086 18203638366 0371-86159066 13526786601 China 2011 60
Shanghai YuLue Chemical Co., Ltd. 021-60345187 13671753212 lzz841106@aliyun.com China 10244 55
Nanjing Chalf-Pharm Technology Co., Ltd. 025-57018978 18251899859 sales@chalf-pharm.com China 5855 50
Shanghai Lollane Biological Technology Co.,Ltd. 021-52996696，15000506266 15000506266 China 4859 55
Shanghai YuanYe Biotechnology Co., Ltd. 15026964105 2881489226@qq.com China 89667 60
Jinan Kaixi Biotechnology Co., Ltd. 13370511208; 15853141736 461667177@qq.com China 764 55
ShangHai Biochempartner Co.,Ltd 177-54423994 17754423994 2853530910@QQ.com China 8000 62
Shanghai SuperLan Chemcial Technique Centre 0-2022843681 15618226720 chaolaichem@foxmail.com China 9996 58
Yantai ShengKailun Chemical Technology Co., Ltd. 13356901049 3119594100@qq.com China 7964 55
Aikon International Limited 025-58859352 19370895928 sales01@aikonchem.com China 15078 58
Supplier Advantage
Candia Thamtech Company Limited 60
Shanghai YuLue Chemical Co., Ltd. 55
Nanjing Chalf-Pharm Technology Co., Ltd. 50
Shanghai Lollane Biological Technology Co.,Ltd. 55
Shanghai YuanYe Biotechnology Co., Ltd. 60
Jinan Kaixi Biotechnology Co., Ltd. 55
ShangHai Biochempartner Co.,Ltd 62
Shanghai SuperLan Chemcial Technique Centre 58
Yantai ShengKailun Chemical Technology Co., Ltd. 55
Aikon International Limited 58

View Latest Price from 2,3-Bis(bromomethyl)quinoxaline 1,4-dioxide manufacturers

Image Update time Product Price Min. Order Purity Supply Ability Manufacturer
Conoidin A pictures 2026-07-14 Conoidin A
18080-67-6
 $43.00-61.00 98.77% 10g TargetMol Chemicals Inc.
  • Conoidin A pictures
  • Conoidin A
    18080-67-6
  • $43.00-61.00
  • 98.77%
  • TargetMol Chemicals Inc.

2,3-Bis(bromomethyl)quinoxaline 1,4-dioxide Spectrum

2,3-BIS(BROMOMETHYL)QUINOXALINE 1,4-DIOXIDE(18080-67-6)1HNMR

18080-67-6 (2,3-Bis(bromomethyl)quinoxaline 1,4-dioxide) Related Search:

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2,3-bis(broMoMethyl)-1-oxoquinoxalin-1-iuM-4(1H)-olate Conoidin A Quinoxaline, 2,3-bis(bromomethyl)-, 1,4-dioxide antioxidative,antioxidant,heart disease,Parasite,Inhibitor,Peroxiredoxin II,hyperperoxidation,Conoidin A,ischaemic,inhibit,neuroprotective Conoidin A, 10 mM in DMSO Peroxiredoxin Inhibitor, Conoidin A 1,4-Dioxo-2,3-dibromomethylquinoline 2,3-Bis(bromomethyl)quinoxaline 1,4-dioxide 18080-67-6 C10H8Br2N2O2