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ChemicalBook >> CAS DataBase List >> 5-Chloro-N-(cyclopropylmethyl)-2-methyl-N-propyl-N'-(2,4,6-trichlorophenyl)-4,6-pyrimidinediamine hydrochloride

5-Chloro-N-(cyclopropylmethyl)-2-methyl-N-propyl-N'-(2,4,6-trichlorophenyl)-4,6-pyrimidinediamine hydrochloride

5-Chloro-N-(cyclopropylmethyl)-2-methyl-N-propyl-N'-(2,4,6-trichlorophenyl)-4,6-pyrimidinediamine hydrochloride price.
  • $105 - $1258
  • Product name: 5-Chloro-N-(cyclopropylmethyl)-2-methyl-N-propyl-N'-(2,4,6-trichlorophenyl)-4,6-pyrimidinediamine hydrochloride
  • CAS: 184241-44-9
  • MF: C18H20Cl4N4
  • MW: 434.19
  • EINECS:
  • MDL Number:MFCD05662281
  • Synonyms:NBI 27914 HYDROCHLORIDE;5-Chloro-N-(cyclopropylmethyl)-2-methyl-N-propyl-N'-(2,4,6-trichlorophenyl)-4,6-pyrimidinediaminehydrochloride;NBI27914HCl;NBI 27914 >=98% (HPLC);NBI 27914 hydrochlor;4,6-Pyrimidinediamine, 5-chloro-N4-(cyclopropylmethyl)-2-methyl-N4-propyl-N6-(2,4,6-trichlorophenyl)-;NBI 27914[N3911];5-Chloro-N-(cyclopropylmethyl)-2-methyl-N-propyl-N'-(2,4,6-trichlorophenyl)-4,6-pyrimidinediamine hydrochloride
24 prices
Selected condition:
Brand
  • aablocks
  • American Custom Chemicals Corporation
  • Arctom
  • ChemScene
  • Sigma-Aldrich
  • Tocris
  • Usbiological
Package
  • 50
  • 5mg
  • 10
  • 10mg
  • 25mg
  • 50mg
  • 10mM*1mLinDMSO(Solution)
  • 100mg
  • 10mM*1mLinDMSO(Solid+Solvent)
  • Manufactureraablocks
  • Product numberAA0075N3
  • Product description5-Chloro-N4-(cyclopropylmethyl)-2-methyl-N4-propyl-N6-(2,4,6-trichlorophenyl)-4,6-pyrimidinediamine >98%
  • Packaging5mg
  • Price$158
  • Updated2026-05-28
  • Buy
  • Manufactureraablocks
  • Product numberAA0075N3
  • Product description5-Chloro-N4-(cyclopropylmethyl)-2-methyl-N4-propyl-N6-(2,4,6-trichlorophenyl)-4,6-pyrimidinediamine >98%
  • Packaging10mg
  • Price$235
  • Updated2026-05-28
  • Buy
  • Manufactureraablocks
  • Product numberAA0075N3
  • Product description5-Chloro-N4-(cyclopropylmethyl)-2-methyl-N4-propyl-N6-(2,4,6-trichlorophenyl)-4,6-pyrimidinediamine >98%
  • Packaging25mg
  • Price$458
  • Updated2026-05-28
  • Buy
  • Manufactureraablocks
  • Product numberAA0075N3
  • Product description5-Chloro-N4-(cyclopropylmethyl)-2-methyl-N4-propyl-N6-(2,4,6-trichlorophenyl)-4,6-pyrimidinediamine >98%
  • Packaging50mg
  • Price$758
  • Updated2026-05-28
  • Buy
  • Manufactureraablocks
  • Product numberAA0075N3
  • Product description5-Chloro-N4-(cyclopropylmethyl)-2-methyl-N4-propyl-N6-(2,4,6-trichlorophenyl)-4,6-pyrimidinediamine >98%
  • Packaging100mg
  • Price$1258
  • Updated2026-05-28
  • Buy
  • ManufacturerAmerican Custom Chemicals Corporation
  • Product numberAPI0008466
  • Product descriptionNBI 27914 95.00%
  • Packaging50MG
  • Price$1170.31
  • Updated2021-12-16
  • Buy
  • ManufacturerAmerican Custom Chemicals Corporation
  • Product numberAPI0008466
  • Product descriptionNBI 27914 95.00%
  • Packaging10MG
  • Price$697.34
  • Updated2021-12-16
  • Buy
  • ManufacturerArctom
  • Product numberHY-135542
  • Product descriptionNBI-27914 99.94%
  • Packaging50mg
  • Price$618
  • Updated2026-05-26
  • Buy
  • ManufacturerArctom
  • Product numberHY-135542
  • Product descriptionNBI-27914 99.94%
  • Packaging25mg
  • Price$361
  • Updated2026-05-26
  • Buy
  • ManufacturerArctom
  • Product numberHY-135542
  • Product descriptionNBI-27914 99.94%
  • Packaging10mg
  • Price$171
  • Updated2026-05-26
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  • ManufacturerArctom
  • Product numberHY-135542
  • Product descriptionNBI-27914 99.94%
  • Packaging5mg
  • Price$105
  • Updated2026-05-26
  • Buy
  • ManufacturerArctom
  • Product numberHY-135542
  • Product descriptionNBI-27914 99.94%
  • Packaging10mM*1mLinDMSO(Solid+Solvent)
  • Price$110
  • Updated2026-05-26
  • Buy
  • ManufacturerArctom
  • Product numberHY-135542
  • Product descriptionNBI-27914 99.94%
  • Packaging10mM*1mLinDMSO(Solution)
  • Price$115
  • Updated2026-05-26
  • Buy
  • ManufacturerArctom
  • Product numberHY-135542
  • Product descriptionNBI-27914 99.94%
  • Packaging100mg
  • Price$1045
  • Updated2026-05-26
  • Buy
  • ManufacturerChemScene
  • Product numberCS-0113422
  • Product descriptionNBI-27914 99.94%
  • Packaging100mg
  • Price$1192
  • Updated2026-06-04
  • Buy
  • ManufacturerChemScene
  • Product numberCS-0113422
  • Product descriptionNBI-27914 99.94%
  • Packaging5mg
  • Price$119
  • Updated2026-06-04
  • Buy
Manufacturer Product number Product description Packaging Price Updated Buy
aablocks AA0075N3 5-Chloro-N4-(cyclopropylmethyl)-2-methyl-N4-propyl-N6-(2,4,6-trichlorophenyl)-4,6-pyrimidinediamine >98% 5mg $158 2026-05-28 Buy
aablocks AA0075N3 5-Chloro-N4-(cyclopropylmethyl)-2-methyl-N4-propyl-N6-(2,4,6-trichlorophenyl)-4,6-pyrimidinediamine >98% 10mg $235 2026-05-28 Buy
aablocks AA0075N3 5-Chloro-N4-(cyclopropylmethyl)-2-methyl-N4-propyl-N6-(2,4,6-trichlorophenyl)-4,6-pyrimidinediamine >98% 25mg $458 2026-05-28 Buy
aablocks AA0075N3 5-Chloro-N4-(cyclopropylmethyl)-2-methyl-N4-propyl-N6-(2,4,6-trichlorophenyl)-4,6-pyrimidinediamine >98% 50mg $758 2026-05-28 Buy
aablocks AA0075N3 5-Chloro-N4-(cyclopropylmethyl)-2-methyl-N4-propyl-N6-(2,4,6-trichlorophenyl)-4,6-pyrimidinediamine >98% 100mg $1258 2026-05-28 Buy
American Custom Chemicals Corporation API0008466 NBI 27914 95.00% 50MG $1170.31 2021-12-16 Buy
American Custom Chemicals Corporation API0008466 NBI 27914 95.00% 10MG $697.34 2021-12-16 Buy
Arctom HY-135542 NBI-27914 99.94% 50mg $618 2026-05-26 Buy
Arctom HY-135542 NBI-27914 99.94% 25mg $361 2026-05-26 Buy
Arctom HY-135542 NBI-27914 99.94% 10mg $171 2026-05-26 Buy
Arctom HY-135542 NBI-27914 99.94% 5mg $105 2026-05-26 Buy
Arctom HY-135542 NBI-27914 99.94% 10mM*1mLinDMSO(Solid+Solvent) $110 2026-05-26 Buy
Arctom HY-135542 NBI-27914 99.94% 10mM*1mLinDMSO(Solution) $115 2026-05-26 Buy
Arctom HY-135542 NBI-27914 99.94% 100mg $1045 2026-05-26 Buy
ChemScene CS-0113422 NBI-27914 99.94% 100mg $1192 2026-06-04 Buy
ChemScene CS-0113422 NBI-27914 99.94% 5mg $119 2026-06-04 Buy

Properties

Boiling point :483.7±45.0 °C(Predicted)
Density :1.417±0.06 g/cm3(Predicted)
storage temp. :2-8°C
solubility :DMSO: 16 mg/mL at 60 °C, soluble
form :solid
pka :3.58±0.50(Predicted)
color :white
InChI :1S/C18H20Cl4N4/c1-3-6-26(9-11-4-5-11)18-15(22)17(23-10(2)24-18)25-16-13(20)7-12(19)8-14(16)21/h7-8,11H,3-6,9H2,1-2H3,(H,23,24,25)
InChIKey :KNADXBVKFAUMCR-UHFFFAOYSA-N
SMILES :CCCN(CC1CC1)c2nc(C)nc(Nc3c(Cl)cc(Cl)cc3Cl)c2Cl

Safety Information

Symbol(GHS): Exclamation Mark (GHS07)
Signal word: Warning
Hazard statements:
Code Hazard statements Hazard class Category Signal word Pictogram P-Codes
H315 Causes skin irritation Skin corrosion/irritation Category 2 Warning P264, P280, P302+P352, P321,P332+P313, P362
H319 Causes serious eye irritation Serious eye damage/eye irritation Category 2A Warning P264, P280, P305+P351+P338,P337+P313P
H335 May cause respiratory irritation Specific target organ toxicity, single exposure;Respiratory tract irritation Category 3 Warning
Precautionary statements:
P261 Avoid breathing dust/fume/gas/mist/vapours/spray.
P305+P351+P338 IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continuerinsing.

Description

NBI 27914 hydrochloride is a selective CRF-RI (type 1 corticotropin-releasing factor; CR1) inhibitor. CRF-RI belongs to the family of CRF receptors, which are involved in modifying the autonomic, behavioral, and endocrine immune response to stress. Anterior pituitary studies indicate that NBI 27914 inhibits CRF-stimulation of cAMP and ACTH release. We supply the NBI 27914 hydrochloride form.

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