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ChemicalBook >> CAS DataBase List >> 3-(5-fluoro-indol-3-yl)-pyrrolidine-2,5-dione

3-(5-fluoro-indol-3-yl)-pyrrolidine-2,5-dione

3-(5-fluoro-indol-3-yl)-pyrrolidine-2,5-dione price.
  • $24 - $1450
  • Product name: 3-(5-fluoro-indol-3-yl)-pyrrolidine-2,5-dione
  • CAS: 198474-05-4
  • MF: C12H9FN2O2
  • MW: 232.21
  • EINECS:
  • MDL Number:MFCD25121820
  • Synonyms:3-(5-fluoro-indol-3-yl)-pyrrolidine-2,5-dione;3-(5-fluoro-1H-indol-3-yl)pyrrolidine-2,5-dione;2,5-Pyrrolidinedione, 3-(5-fluoro-1H-indol-3-yl)-;3-(5-Fluoro-1H-indol-3-yl)-2,5-pyrrolidinedione;PF-06840003 (racemate);EOS200271;PF 06840003;PF-06840003;EOS200271 PF-06840003
Price51 Properties Safety Information Description
51 prices
Selected condition：
Brand
  • aablocks
  • Abosyn
  • ACHEMBLOCK
  • AK Scientific
  • Ambeed
  • American Custom Chemicals Corporation
  • Arctom
  • AvaChem
  • Axon Medchem
  • Biorbyt Ltd
  • Biosynth
  • Cayman Chemical
  • Chemenu
  • ChemScene
  • Crysdot
  • CSNpharm
  • DC Chemicals
  • TRC
Package
  • 10mM*1mLinDMSO(Solid+Solvent)
  • 1mg
  • 2mg
  • 5mg
  • 10mg
  • 25mg
  • 50mg
  • 10mM*1mLinDMSO(Solution)
  • 100mg
  • 250mg
  • 500mg
  • 1g
  • Manufactureraablocks
  • Product numberAA002BG4
  • Product descriptionPF-06840003 99%
  • Packaging1mg
  • Price$24
  • Updated2026-05-28
  • Buy
  • Manufactureraablocks
  • Product numberAA002BG4
  • Product descriptionPF-06840003 99%
  • Packaging5mg
  • Price$35
  • Updated2026-05-28
  • Buy
  • Manufactureraablocks
  • Product numberAA002BG4
  • Product descriptionPF-06840003 ≥98%
  • Packaging10mg
  • Price$49
  • Updated2026-05-28
  • Buy
  • Manufactureraablocks
  • Product numberAA002BG4
  • Product descriptionPF-06840003 99%
  • Packaging25mg
  • Price$78
  • Updated2026-05-28
  • Buy
  • Manufactureraablocks
  • Product numberAA002BG4
  • Product descriptionPF-06840003 99%
  • Packaging50mg
  • Price$94
  • Updated2026-05-28
  • Buy
  • Manufactureraablocks
  • Product numberAA002BG4
  • Product descriptionPF-06840003 99%
  • Packaging100mg
  • Price$145
  • Updated2026-05-28
  • Buy
  • ManufacturerAbosyn
  • Product number21-1093
  • Product description3-(5-fluoro-1H-indol-3-yl)pyrrolidine-2,5-dione 95%-98%
  • Packaging1g
  • Price$525
  • Updated2021-12-16
  • Buy
  • ManufacturerACHEMBLOCK
  • Product numberL18334
  • Product descriptionPF-06840003 98%
  • Packaging100MG
  • Price$63
  • Updated2026-05-27
  • Buy
  • ManufacturerACHEMBLOCK
  • Product numberL18334
  • Product descriptionPF-06840003 98%
  • Packaging1G
  • Price$324
  • Updated2026-05-27
  • Buy
  • ManufacturerAK Scientific
  • Product number7203DA
  • Product description3-(5-Fluoro-1H-indol-3-yl)pyrrolidine-2,5-dione
  • Packaging50mg
  • Price$173
  • Updated2021-12-16
  • Buy
  • ManufacturerAmbeed
  • Product numberA196131
  • Product descriptionPF-06840003 98%
  • Packaging10mg
  • Price$95
  • Updated2021-12-16
  • Buy
  • ManufacturerAmerican Custom Chemicals Corporation
  • Product numberHCH0621043
  • Product description3-(5-FLUORO-1H-INDOL-3-YL)PYRROLIDINE-2,5-DIONE 95.00%
  • Packaging5MG
  • Price$454.59
  • Updated2021-12-16
  • Buy
  • ManufacturerArctom
  • Product numberSLK-S8657
  • Product descriptionPF-06840003 99.97%
  • Packaging25mg
  • Price$425
  • Updated2026-05-26
  • Buy
  • ManufacturerArctom
  • Product numberHY-101111
  • Product descriptionPF-06840003 99.87%
  • Packaging10mM*1mLinDMSO(Solution)
  • Price$63
  • Updated2026-05-26
  • Buy
  • ManufacturerArctom
  • Product numberHY-101111
  • Product descriptionPF-06840003 99.87%
  • Packaging10mM*1mLinDMSO(Solid+Solvent)
  • Price$60
  • Updated2026-05-26
  • Buy
  • ManufacturerArctom
  • Product numberHY-101111
  • Product descriptionPF-06840003 99.87%
  • Packaging5mg
  • Price$57
  • Updated2026-05-26
  • Buy
Manufacturer Product number Product description Packaging Price Updated Buy
aablocks AA002BG4 PF-06840003 99% 1mg $24 2026-05-28 Buy
aablocks AA002BG4 PF-06840003 99% 5mg $35 2026-05-28 Buy
aablocks AA002BG4 PF-06840003 ≥98% 10mg $49 2026-05-28 Buy
aablocks AA002BG4 PF-06840003 99% 25mg $78 2026-05-28 Buy
aablocks AA002BG4 PF-06840003 99% 50mg $94 2026-05-28 Buy
aablocks AA002BG4 PF-06840003 99% 100mg $145 2026-05-28 Buy
Abosyn 21-1093 3-(5-fluoro-1H-indol-3-yl)pyrrolidine-2,5-dione 95%-98% 1g $525 2021-12-16 Buy
ACHEMBLOCK L18334 PF-06840003 98% 100MG $63 2026-05-27 Buy
ACHEMBLOCK L18334 PF-06840003 98% 1G $324 2026-05-27 Buy
AK Scientific 7203DA 3-(5-Fluoro-1H-indol-3-yl)pyrrolidine-2,5-dione 50mg $173 2021-12-16 Buy
Ambeed A196131 PF-06840003 98% 10mg $95 2021-12-16 Buy
American Custom Chemicals Corporation HCH0621043 3-(5-FLUORO-1H-INDOL-3-YL)PYRROLIDINE-2,5-DIONE 95.00% 5MG $454.59 2021-12-16 Buy
Arctom SLK-S8657 PF-06840003 99.97% 25mg $425 2026-05-26 Buy
Arctom HY-101111 PF-06840003 99.87% 10mM*1mLinDMSO(Solution) $63 2026-05-26 Buy
Arctom HY-101111 PF-06840003 99.87% 10mM*1mLinDMSO(Solid+Solvent) $60 2026-05-26 Buy
Arctom HY-101111 PF-06840003 99.87% 5mg $57 2026-05-26 Buy
Next Last

Properties

Melting point :190-195 °C
Boiling point :533.2±50.0 °C(Predicted)
Density :1.464±0.06 g/cm3(Predicted)
storage temp. :Inert atmosphere,Room Temperature
solubility :Soluble in DMSO (up to at least 25 mg/ml)
form :solid
pka :9.13±0.50(Predicted)
color :White
Stability :Stable for 1 year from date of purchase as supplied. Solutions in DMSO may be stored at -20°C for up to 3 months.

Safety Information

Symbol(GHS): Exclamation Mark (GHS07)
Signal word: Warning
Hazard statements:
Code Hazard statements Hazard class Category Signal word Pictogram P-Codes
H302 Harmful if swallowed Acute toxicity,oral Category 4 Warning P264, P270, P301+P312, P330, P501
H315 Causes skin irritation Skin corrosion/irritation Category 2 Warning P264, P280, P302+P352, P321,P332+P313, P362
H319 Causes serious eye irritation Serious eye damage/eye irritation Category 2A Warning P264, P280, P305+P351+P338,P337+P313P
H335 May cause respiratory irritation Specific target organ toxicity, single exposure;Respiratory tract irritation Category 3 Warning
Precautionary statements:
P261 Avoid breathing dust/fume/gas/mist/vapours/spray.
P264 Wash hands thoroughly after handling.
P264 Wash skin thouroughly after handling.
P270 Do not eat, drink or smoke when using this product.
P271 Use only outdoors or in a well-ventilated area.
P280 Wear protective gloves/protective clothing/eye protection/face protection.
P301+P312 IF SWALLOWED: call a POISON CENTER or doctor/physician IF you feel unwell.
P302+P352 IF ON SKIN: wash with plenty of soap and water.
P304+P340 IF INHALED: Remove victim to fresh air and Keep at rest in a position comfortable for breathing.
P305+P351+P338 IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continuerinsing.
P321 Specific treatment (see … on this label).
P330 Rinse mouth.
P332+P313 IF SKIN irritation occurs: Get medical advice/attention.
P337+P313 IF eye irritation persists: Get medical advice/attention.
P403+P233 Store in a well-ventilated place. Keep container tightly closed.
P405 Store locked up.
P501 Dispose of contents/container to..…

Description

PF-06840003 (198474-05-4) is a potent (IC50= 150 and 410 nM via two methods) and selective inhibitor of Indoleamine-2,3-dioxygenase (IDO1).1In mice with syngeneic tumor grafts, it reduced intratumoral kynurenine levels by over 80%, inhibited tumor growth as monotherapy, and increased the efficacy of anti-PD-L1 therapy.2PF-06840003 treatment combined with GM-CSF-secreting allogenic pancreatic tumor cell vaccine (GVAX) resulted in increased antitumor efficacy in a murine model of pancreatic ductal adenocarcinoma.3

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Suppliers and manufacturers

Shanghai Boyle Chemical Co., Ltd. Chembest Research Laboratories Limited Shanghai Hanhong Scientific Co.,Ltd. BOC Sciences Dalian Meilun Biotech Co., Ltd. Shanghai Topbiochem Technology Co., Ltd ShangHai Caerulum Pharma Discovery Co., Ltd. Bide Pharmatech Ltd. Shanghai Balmxy Pharmaceutical Co., Ltd Hangzhou J&H Chemical Co., Ltd.