PF-6274484
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- $34 - $2200
- Product name: PF-6274484
- CAS: 1035638-91-5
- MF: C18H14ClFN4O2
- MW: 372.78
- EINECS:
- MDL Number:MFCD30182370
- Synonyms:PF-6274484;N-[4-[(3-Chloro-4-fluorophenyl)amino]-7-methoxy-6-quinazolinyl]-2-propenamide;2-Propenamide, N-[4-[(3-chloro-4-fluorophenyl)amino]-7-methoxy-6-quinazolinyl]-;PF-6274484 >=98% (HPLC);oxidation,autophosphorylation,PF6274484,PF-6274484,EGFR,signaling,Epidermal growth factor receptor,HER1,protein,ErbB-1,inhibit,kinase,cysteine,Inhibitor;N-(4-((3-Chloro-4-fluorophenyl)amino)-7-methoxyquinazolin-6-yl)acrylamide;PF-6274484, 10 mM in DMSO
8 prices
Selected condition:
Brand
- AK Scientific
- Cayman Chemical
- DC Chemicals
- TRC
Package
- 1mg
- 5mg
- 10mg
- 50mg
- 250mg
- 1g
- ManufacturerAK Scientific
- Product number8711DW
- Product descriptionN-[4-(3-Chloro-4-fluoroanilino)-7-methoxyquinazolin-6-yl]prop-2-enamide
- Packaging5mg
- Price$209
- Updated2021-12-16
- Buy
- ManufacturerAK Scientific
- Product number8711DW
- Product descriptionN-[4-(3-Chloro-4-fluoroanilino)-7-methoxyquinazolin-6-yl]prop-2-enamide
- Packaging10mg
- Price$302
- Updated2021-12-16
- Buy
- ManufacturerCayman Chemical
- Product number22698
- Product descriptionPF-6274484 ≥98%
- Packaging1mg
- Price$34
- Updated2024-03-01
- Buy
- ManufacturerCayman Chemical
- Product number22698
- Product descriptionPF-6274484 ≥98%
- Packaging5mg
- Price$100
- Updated2024-03-01
- Buy
- ManufacturerCayman Chemical
- Product number22698
- Product descriptionPF-6274484 ≥98%
- Packaging10mg
- Price$166
- Updated2024-03-01
- Buy
- ManufacturerDC Chemicals
- Product numberDC11320
- Product descriptionPF-6274484 >98%
- Packaging250mg
- Price$1100
- Updated2021-12-16
- Buy
- ManufacturerDC Chemicals
- Product numberDC11320
- Product descriptionPF-6274484 >98%
- Packaging1g
- Price$2200
- Updated2021-12-16
- Buy
- ManufacturerTRC
- Product numberP294153
- Product descriptionPF6274484
- Packaging50mg
- Price$820
- Updated2021-12-16
- Buy
Manufacturer | Product number | Product description | Packaging | Price | Updated | Buy |
---|---|---|---|---|---|---|
AK Scientific | 8711DW | N-[4-(3-Chloro-4-fluoroanilino)-7-methoxyquinazolin-6-yl]prop-2-enamide | 5mg | $209 | 2021-12-16 | Buy |
AK Scientific | 8711DW | N-[4-(3-Chloro-4-fluoroanilino)-7-methoxyquinazolin-6-yl]prop-2-enamide | 10mg | $302 | 2021-12-16 | Buy |
Cayman Chemical | 22698 | PF-6274484 ≥98% | 1mg | $34 | 2024-03-01 | Buy |
Cayman Chemical | 22698 | PF-6274484 ≥98% | 5mg | $100 | 2024-03-01 | Buy |
Cayman Chemical | 22698 | PF-6274484 ≥98% | 10mg | $166 | 2024-03-01 | Buy |
DC Chemicals | DC11320 | PF-6274484 >98% | 250mg | $1100 | 2021-12-16 | Buy |
DC Chemicals | DC11320 | PF-6274484 >98% | 1g | $2200 | 2021-12-16 | Buy |
TRC | P294153 | PF6274484 | 50mg | $820 | 2021-12-16 | Buy |
Properties
storage temp. :Store at -20°C
solubility :DMF: 33 mg/ml; DMSO: 25 mg/ml
form :A crystalline solid
color :Light yellow to orange
solubility :DMF: 33 mg/ml; DMSO: 25 mg/ml
form :A crystalline solid
color :Light yellow to orange
Safety Information
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Description
PF-6274484 is an irreversible EGFR kinase inhibitor that covalently reacts with active-site cysteine residues in the ATP binding pocket. PF-6274484 inhibits autophosphorylation of both wild type and mutant EGFR in tumor cells with IC50 values of 5.8 nM and 6.6 nM, respectively.More related product prices
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