Welcome to chemicalbook!
China English Japan Germany
010-86108875
18162-48-6872-50-4Methylene ChloridenaphthaleneTHFTitanium Dioxide
Structure Search
RFQ
Try our best to find the right business for you.
Messages
Do not miss inquiry messages Please log in to view all inquiry messages.
My chemicalbook Sign in

Welcome back!

RFQ
skype
MY Account
Top
ChemicalBook >> CAS DataBase List >> (2R,3R,4S,5R)-2-(4-aminopyrrolo[2,3-d]pyrimidin-7-yl)-5[(R)-hydroxy(phenyl)methyl]tetrahydrofuran-3,4-diol

(2R,3R,4S,5R)-2-(4-aminopyrrolo[2,3-d]pyrimidin-7-yl)-5[(R)-hydroxy(phenyl)methyl]tetrahydrofuran-3,4-diol

(2R,3R,4S,5R)-2-(4-aminopyrrolo[2,3-d]pyrimidin-7-yl)-5[(R)-hydroxy(phenyl)methyl]tetrahydrofuran-3,4-diol price.
  • $36 - $3074
  • Product name: (2R,3R,4S,5R)-2-(4-aminopyrrolo[2,3-d]pyrimidin-7-yl)-5[(R)-hydroxy(phenyl)methyl]tetrahydrofuran-3,4-diol
  • CAS: 2040291-27-6
  • MF: C17H18N4O4
  • MW: 342.35
  • EINECS:
  • MDL Number:MFCD31657362
  • Synonyms:(2R,3R,4S,5R)-2-(4-aminopyrrolo[2,3-d]pyrimidin-7-yl)-5[(R)-hydroxy(phenyl)methyl]tetrahydrofuran-3,4-diol;LM-5179;LLY-283 (LLY283);7H-Pyrrolo[2,3-d]pyrimidin-4-amine, 7-[(5R)-5-C-phenyl-β-D-ribofuranosyl]-;LLY-283 >=98% (HPLC);7-[(5R)-5-CPhenyl-β-D-ribofuranosyl]-7H-pyrrolo[2,3-d]pyrimidin-4-amine;(2R,3R,4S,5R)-2-(4-Amino-7H-pyrrolo[2,3-d]pyrimidin-7-yl)-5-((R)-hydroxy(phenyl)methyl)tetrahydrofuran-3,4-diol;LLY-283, 10 mM in DMSO
Price27 Properties Safety Information Description
27 prices
Selected condition：
Brand
  • aablocks
  • ACHEMBLOCK
  • AK Scientific
  • Arctom
  • Biosynth
  • Cayman Chemical
  • ChemScene
  • DC Chemicals
  • Sigma-Aldrich
Package
  • 10mM(1mLinDMSO)
  • 1mg
  • 5mg
  • 10mg
  • 25mg
  • 50mg
  • 100mg
  • 250mg
  • 1g
  • 5 mg
  • 25 mg
  • Manufactureraablocks
  • Product numberAA01FTQ4
  • Product description(2R,3R,4S,5R)-2-(4-Amino-7H-pyrrolo[2,3-d]pyrimidin-7-yl)-5-((R)-hydroxy(phenyl)methyl)tetrahydrofuran-3,4-diol ≥98%
  • Packaging1mg
  • Price$36
  • Updated2026-05-30
  • Buy
  • Manufactureraablocks
  • Product numberAA01FTQ4
  • Product description(2R,3R,4S,5R)-2-(4-Amino-7H-pyrrolo[2,3-d]pyrimidin-7-yl)-5-((R)-hydroxy(phenyl)methyl)tetrahydrofuran-3,4-diol 99%
  • Packaging5mg
  • Price$53
  • Updated2026-05-30
  • Buy
  • Manufactureraablocks
  • Product numberAA01FTQ4
  • Product description(2R,3R,4S,5R)-2-(4-Amino-7H-pyrrolo[2,3-d]pyrimidin-7-yl)-5-((R)-hydroxy(phenyl)methyl)tetrahydrofuran-3,4-diol 99%
  • Packaging10mg
  • Price$87
  • Updated2026-05-30
  • Buy
  • Manufactureraablocks
  • Product numberAA01FTQ4
  • Product description(2R,3R,4S,5R)-2-(4-Amino-7H-pyrrolo[2,3-d]pyrimidin-7-yl)-5-((R)-hydroxy(phenyl)methyl)tetrahydrofuran-3,4-diol 99%
  • Packaging25mg
  • Price$176
  • Updated2026-05-30
  • Buy
  • Manufactureraablocks
  • Product numberAA01FTQ4
  • Product description(2R,3R,4S,5R)-2-(4-Amino-7H-pyrrolo[2,3-d]pyrimidin-7-yl)-5-((R)-hydroxy(phenyl)methyl)tetrahydrofuran-3,4-diol 99%
  • Packaging50mg
  • Price$298
  • Updated2026-05-30
  • Buy
  • Manufactureraablocks
  • Product numberAA01FTQ4
  • Product description(2R,3R,4S,5R)-2-(4-Amino-7H-pyrrolo[2,3-d]pyrimidin-7-yl)-5-((R)-hydroxy(phenyl)methyl)tetrahydrofuran-3,4-diol 99%
  • Packaging100mg
  • Price$505
  • Updated2026-05-30
  • Buy
  • ManufacturerACHEMBLOCK
  • Product numberZ238315
  • Product descriptionLLY-283 98%
  • Packaging100MG
  • Price$645
  • Updated2026-05-27
  • Buy
  • ManufacturerACHEMBLOCK
  • Product numberZ238315
  • Product descriptionLLY-283 98%
  • Packaging25MG
  • Price$225
  • Updated2026-05-27
  • Buy
  • ManufacturerAK Scientific
  • Product number3430EH
  • Product descriptionCID122669401
  • Packaging25mg
  • Price$606
  • Updated2021-12-16
  • Buy
  • ManufacturerArctom
  • Product numberSLK-S8883
  • Product descriptionLLY-283 99.12%
  • Packaging10mM(1mLinDMSO)
  • Price$188
  • Updated2026-05-26
  • Buy
  • ManufacturerArctom
  • Product numberSLK-S8883
  • Product descriptionLLY-283 99.12%
  • Packaging25mg
  • Price$323
  • Updated2026-05-26
  • Buy
  • ManufacturerArctom
  • Product numberSLK-S8883
  • Product descriptionLLY-283 99.12%
  • Packaging5mg
  • Price$140
  • Updated2026-05-26
  • Buy
  • ManufacturerBiosynth
  • Product numberBL166665
  • Product descriptionLLY 283
  • Packaging100mg
  • Price$3074
  • Updated2026-06-04
  • Buy
  • ManufacturerCayman Chemical
  • Product number21596
  • Product descriptionLLY-283 ≥98%
  • Packaging5mg
  • Price$153
  • Updated2026-04-30
  • Buy
  • ManufacturerCayman Chemical
  • Product number21596
  • Product descriptionLLY-283 ≥98%
  • Packaging10mg
  • Price$268
  • Updated2026-04-30
  • Buy
  • ManufacturerCayman Chemical
  • Product number21596
  • Product descriptionLLY-283 ≥98%
  • Packaging25mg
  • Price$502
  • Updated2026-04-30
  • Buy
Manufacturer Product number Product description Packaging Price Updated Buy
aablocks AA01FTQ4 (2R,3R,4S,5R)-2-(4-Amino-7H-pyrrolo[2,3-d]pyrimidin-7-yl)-5-((R)-hydroxy(phenyl)methyl)tetrahydrofuran-3,4-diol ≥98% 1mg $36 2026-05-30 Buy
aablocks AA01FTQ4 (2R,3R,4S,5R)-2-(4-Amino-7H-pyrrolo[2,3-d]pyrimidin-7-yl)-5-((R)-hydroxy(phenyl)methyl)tetrahydrofuran-3,4-diol 99% 5mg $53 2026-05-30 Buy
aablocks AA01FTQ4 (2R,3R,4S,5R)-2-(4-Amino-7H-pyrrolo[2,3-d]pyrimidin-7-yl)-5-((R)-hydroxy(phenyl)methyl)tetrahydrofuran-3,4-diol 99% 10mg $87 2026-05-30 Buy
aablocks AA01FTQ4 (2R,3R,4S,5R)-2-(4-Amino-7H-pyrrolo[2,3-d]pyrimidin-7-yl)-5-((R)-hydroxy(phenyl)methyl)tetrahydrofuran-3,4-diol 99% 25mg $176 2026-05-30 Buy
aablocks AA01FTQ4 (2R,3R,4S,5R)-2-(4-Amino-7H-pyrrolo[2,3-d]pyrimidin-7-yl)-5-((R)-hydroxy(phenyl)methyl)tetrahydrofuran-3,4-diol 99% 50mg $298 2026-05-30 Buy
aablocks AA01FTQ4 (2R,3R,4S,5R)-2-(4-Amino-7H-pyrrolo[2,3-d]pyrimidin-7-yl)-5-((R)-hydroxy(phenyl)methyl)tetrahydrofuran-3,4-diol 99% 100mg $505 2026-05-30 Buy
ACHEMBLOCK Z238315 LLY-283 98% 100MG $645 2026-05-27 Buy
ACHEMBLOCK Z238315 LLY-283 98% 25MG $225 2026-05-27 Buy
AK Scientific 3430EH CID122669401 25mg $606 2021-12-16 Buy
Arctom SLK-S8883 LLY-283 99.12% 10mM(1mLinDMSO) $188 2026-05-26 Buy
Arctom SLK-S8883 LLY-283 99.12% 25mg $323 2026-05-26 Buy
Arctom SLK-S8883 LLY-283 99.12% 5mg $140 2026-05-26 Buy
Biosynth BL166665 LLY 283 100mg $3074 2026-06-04 Buy
Cayman Chemical 21596 LLY-283 ≥98% 5mg $153 2026-04-30 Buy
Cayman Chemical 21596 LLY-283 ≥98% 10mg $268 2026-04-30 Buy
Cayman Chemical 21596 LLY-283 ≥98% 25mg $502 2026-04-30 Buy
Next Last

Properties

Boiling point :688.9±55.0 °C(Predicted)
Density :1+-.0.1 g/cm3(Predicted)
storage temp. :Store at -20°C
solubility :DMSO: 60 mg/ml; Ethanol: 60 mg/ml
form :A crystalline solid
pka :12.46±0.70(Predicted)
color :White to off-white
InChIKey :WWOOWAHTEXIWBO-QFRSUPTLSA-N
SMILES :O[C@@H]1[C@@H]([C@H](O)C2=CC=CC=C2)O[C@@H](N3C(N=CN=C4N)=C4C=C3)[C@@H]1O

Safety Information

Symbol(GHS):
Signal word:
Hazard statements:
Code Hazard statements Hazard class Category Signal word Pictogram P-Codes
Precautionary statements:

Description

LLY-283 is an inhibitor of protein arginine methyltransferase 5 (PRMT5; IC50 = 22 nM). It is selective for PRMT5 over a panel of methyltransferases, including PRMT4, -6, and -7 at 1 μM. It reduces symmetric demethylation of SmBB'' in MCF-7 cells (IC50 = 25 nM) and inhibits proliferation of various breast, gastric, hematological, lung, skin, and ovarian cancer cell lines (IC50s = 3-30 nM). LLY-283 (20 mg/kg) inhibits tumor growth in an A375 mouse xenograft model. It also disrupts alternative splicing events in, and inhibits proliferation and self-renewal of, patient-derived glioblastoma stem cells and increases survival in an orthotopic patient-derived xenograft (PDX) mouse model. See the Structural Genomics Consortium (SGC) website for more information.

More related product prices

606-58-6 TUBERCIDIN

Related product price

Suppliers and manufacturers

BOC Sciences ShangHai Caerulum Pharma Discovery Co., Ltd. Shanghaizehan biopharma technology co., Ltd. Shanghai EFE Biological Technology Co., Ltd. Shanghai YuanYe Biotechnology Co., Ltd. ShangHai Biochempartner Co.,Ltd Shanghai SuperLan Chemcial Technique Centre Beijing Solarbio Science & Tecnology Co., Ltd. Amadis Chemical Company Limited Chuzhou KeMail Chemical Technology Co., Ltd