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ChemicalBook >> CAS DataBase List >> 5-Chloro-N-[4-methoxy-3-(1-piperazinyl)phenyl]-3-methylbenzo[b]thiophene-2-sulfonamide hydrochloride

5-Chloro-N-[4-methoxy-3-(1-piperazinyl)phenyl]-3-methylbenzo[b]thiophene-2-sulfonamide hydrochloride

$56 - $1800
Product name: 5-Chloro-N-[4-methoxy-3-(1-piperazinyl)phenyl]-3-methylbenzo[b]thiophene-2-sulfonamide hydrochloride
CAS: 209481-24-3
MF: C20H23Cl2N3O3S2
MW: 488.44
EINECS:
MDL Number:MFCD10565914
Synonyms:5-Chloro-N-[4-methoxy-3-(1-piperazinyl)phenyl]-3-methylbenzo[b]thiophene-2-sulfonamide hydrochloride;SB 271046A;Benzo[b]thiophene-2-sulfonaMide, 5-chloro-N-[4-Methoxy-3-(1-piperazinyl)phenyl]-3-Methyl-, Monohydrochloride;5-Chloro-N-(4-methoxy-3-piperazin-1-yl-phenyl)-3-methyl-2-benzo-thiophenesulfonamide hydrochloride;4-[(3-chloro-1,4-dioxonaphthalen-2-yl)amino]benzenesulfonamide;SB 271046A; SB-271046A;SB-271046A >=98% (HPLC);SB 271046 HCl (SB-271046A)

Price29 Properties Safety Information Description

29 prices

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Brand

aablocks
AK Scientific
Axon Medchem
Biosynth
Cayman Chemical
Chemenu
ChemScene
Crysdot
DC Chemicals
Sigma-Aldrich
TRC
Usbiological

Package

5mg
10mg
25mg
50mg
100mg
250mg
1g

Manufactureraablocks
Product numberAA00BE88
Product description5-Chloro-N-(4-methoxy-3-(piperazin-1-yl)phenyl)-3-methylbenzo[b]thiophene-2-sulfonamide hydrochloride ≥99%
Packaging5mg
Price$56
Updated2026-05-28
Buy

Manufactureraablocks
Product numberAA00BE88
Product description5-Chloro-N-(4-methoxy-3-(piperazin-1-yl)phenyl)-3-methylbenzo[b]thiophene-2-sulfonamide hydrochloride ≥99%
Packaging10mg
Price$99
Updated2026-05-28
Buy

Manufactureraablocks
Product numberAA00BE88
Product description5-Chloro-N-(4-methoxy-3-(piperazin-1-yl)phenyl)-3-methylbenzo[b]thiophene-2-sulfonamide hydrochloride ≥99%
Packaging25mg
Price$217
Updated2026-05-28
Buy

Manufactureraablocks
Product numberAA00BE88
Product description5-Chloro-N-(4-methoxy-3-(piperazin-1-yl)phenyl)-3-methylbenzo[b]thiophene-2-sulfonamide hydrochloride ≥99%
Packaging50mg
Price$355
Updated2026-05-28
Buy

Manufactureraablocks
Product numberAA00BE88
Product description5-Chloro-N-(4-methoxy-3-(piperazin-1-yl)phenyl)-3-methylbenzo[b]thiophene-2-sulfonamide hydrochloride ≥99%
Packaging100mg
Price$640
Updated2026-05-28
Buy

ManufacturerAK Scientific
Product numberSYN5671
Product descriptionSB271046hydrochloride
Packaging50mg
Price$582
Updated2021-12-16
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ManufacturerAxon Medchem
Product numberAxon1099
Product descriptionSB 271046 hydrochloride
Packaging50mg
Price$368.5
Updated2026-05-19
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ManufacturerAxon Medchem
Product numberAxon1099
Product descriptionSB 271046 hydrochloride
Packaging10mg
Price$104.5
Updated2026-05-19
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ManufacturerBiosynth
Product numberFS65160
Product descriptionSB 271046 hydrochloride
Packaging50mg
Price$757
Updated2026-06-04
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ManufacturerBiosynth
Product numberFS65160
Product descriptionSB 271046 hydrochloride
Packaging10mg
Price$215.9
Updated2026-06-04
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ManufacturerCayman Chemical
Product number18513
Product descriptionSB-271046 (hydrochloride) ≥95%
Packaging50mg
Price$696
Updated2026-04-30
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ManufacturerCayman Chemical
Product number18513
Product descriptionSB-271046 (hydrochloride) ≥95%
Packaging10mg
Price$168
Updated2026-04-30
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ManufacturerCayman Chemical
Product number18513
Product descriptionSB-271046 (hydrochloride) ≥95%
Packaging5mg
Price$90
Updated2026-04-30
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ManufacturerCayman Chemical
Product number18513
Product descriptionSB-271046 (hydrochloride) ≥95%
Packaging25mg
Price$392
Updated2026-04-30
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ManufacturerChemenu
Product numberCM161542
Product description5-chloro-N-(4-methoxy-3-(piperazin-1-yl)phenyl)-3-methylbenzo[b]thiophene-2-sulfonamide hydrochloride 98%
Packaging50mg
Price$268
Updated2026-05-26
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ManufacturerChemScene
Product numberCS-0634
Product descriptionSB 271046 Hydrochloride 99.93%
Packaging5mg
Price$93
Updated2026-06-04
Buy

Manufacturer	Product number	Product description	Packaging	Price	Updated	Buy
aablocks	AA00BE88	5-Chloro-N-(4-methoxy-3-(piperazin-1-yl)phenyl)-3-methylbenzo[b]thiophene-2-sulfonamide hydrochloride ≥99%	5mg	$56	2026-05-28	Buy
aablocks	AA00BE88	5-Chloro-N-(4-methoxy-3-(piperazin-1-yl)phenyl)-3-methylbenzo[b]thiophene-2-sulfonamide hydrochloride ≥99%	10mg	$99	2026-05-28	Buy
aablocks	AA00BE88	5-Chloro-N-(4-methoxy-3-(piperazin-1-yl)phenyl)-3-methylbenzo[b]thiophene-2-sulfonamide hydrochloride ≥99%	25mg	$217	2026-05-28	Buy
aablocks	AA00BE88	5-Chloro-N-(4-methoxy-3-(piperazin-1-yl)phenyl)-3-methylbenzo[b]thiophene-2-sulfonamide hydrochloride ≥99%	50mg	$355	2026-05-28	Buy
aablocks	AA00BE88	5-Chloro-N-(4-methoxy-3-(piperazin-1-yl)phenyl)-3-methylbenzo[b]thiophene-2-sulfonamide hydrochloride ≥99%	100mg	$640	2026-05-28	Buy
AK Scientific	SYN5671	SB271046hydrochloride	50mg	$582	2021-12-16	Buy
Axon Medchem	Axon1099	SB 271046 hydrochloride	50mg	$368.5	2026-05-19	Buy
Axon Medchem	Axon1099	SB 271046 hydrochloride	10mg	$104.5	2026-05-19	Buy
Biosynth	FS65160	SB 271046 hydrochloride	50mg	$757	2026-06-04	Buy
Biosynth	FS65160	SB 271046 hydrochloride	10mg	$215.9	2026-06-04	Buy
Cayman Chemical	18513	SB-271046 (hydrochloride) ≥95%	50mg	$696	2026-04-30	Buy
Cayman Chemical	18513	SB-271046 (hydrochloride) ≥95%	10mg	$168	2026-04-30	Buy
Cayman Chemical	18513	SB-271046 (hydrochloride) ≥95%	5mg	$90	2026-04-30	Buy
Cayman Chemical	18513	SB-271046 (hydrochloride) ≥95%	25mg	$392	2026-04-30	Buy
Chemenu	CM161542	5-chloro-N-(4-methoxy-3-(piperazin-1-yl)phenyl)-3-methylbenzo[b]thiophene-2-sulfonamide hydrochloride 98%	50mg	$268	2026-05-26	Buy
ChemScene	CS-0634	SB 271046 Hydrochloride 99.93%	5mg	$93	2026-06-04	Buy

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Properties

storage temp. :2-8°C
solubility :DMSO: >20mg/mL
form :powder
color :White to light brown
InChI :1S/C20H22ClN3O3S2.ClH/c1-13-16-11-14(21)3-6-19(16)28-20(13)29(25,26)23-15-4-5-18(27-2)17(12-15)24-9-7-22-8-10-24;/h3-6,11-12,22-23H,7-10H2,1-2H3;1H
InChIKey :RMXZRJYGJMSDQK-UHFFFAOYSA-N
SMILES :Cl.COc1ccc(NS(=O)(=O)c2sc3ccc(Cl)cc3c2C)cc1N4CCNCC4

Safety Information

Symbol(GHS):

Signal word:

Warning

Hazard statements:

Code	Hazard statements	Hazard class	Category	Signal word	P-Codes
H302	Harmful if swallowed	Acute toxicity,oral	Category 4	Warning	P264, P270, P301+P312, P330, P501
H315	Causes skin irritation	Skin corrosion/irritation	Category 2	Warning	P264, P280, P302+P352, P321,P332+P313, P362
H319	Causes serious eye irritation	Serious eye damage/eye irritation	Category 2A	Warning	P264, P280, P305+P351+P338,P337+P313P
H335	May cause respiratory irritation	Specific target organ toxicity, single exposure;Respiratory tract irritation	Category 3	Warning

Precautionary statements:

P261	Avoid breathing dust/fume/gas/mist/vapours/spray.
P305+P351+P338	IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continuerinsing.

Description

SB-271046 is an orally-available antagonist of the serotonin (5-hydroxytryptamine, or 5-HT; ) receptor 5-HT6 (pKi = 9.02-8.92). It is at least 100-fold selective for 5-HT6 over other 5-HT receptors, as well as 55 other receptors, enzymes, and ion channels. While it does not alter basal levels of 5-HT, dopamine, or noradrenaline, SB-271046 produces a significant increase in extracellular levels of glutamate and aspartate within the frontal cortex. It has been used to evaluate the role of 5-HT6 in learning and memory.

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Suppliers and manufacturers

Chembest Research Laboratories Limited Hangzhou Sage Chemical Co., Ltd. Haoyuan Chemexpress Co., Ltd. LETOPHARM LIMITED SPIRO PHARMA Henan CoreyChem Co., Ltd Shanghai EFE Biological Technology Co., Ltd. Guangzhou QiYun Biotechnology Co., Ltd. Shanghai YuanYe Biotechnology Co., Ltd. Shanghai Rechem science Co., Ltd.

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5-Chloro-N-[4-methoxy-3-(1-piperazinyl)phenyl]-3-methylbenzo[b]thiophene-2-sulfonamide hydrochloride

Properties

Safety Information

Description

Related product price

Suppliers and manufacturers