1-Oxazolo[4,5-b]pyridin-2-yl-6-phenylhexan-1-one
![1-Oxazolo[4,5-b]pyridin-2-yl-6-phenylhexan-1-one price.](/CAS/GIF/288862-83-9.gif)
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- $54 - $1887
- Product name: 1-Oxazolo[4,5-b]pyridin-2-yl-6-phenylhexan-1-one
- CAS: 288862-83-9
- MF: C18H18N2O2
- MW: 294.35
- EINECS:
- MDL Number:MFCD28963803
- Synonyms:PHENYL HEXANOYL OXAZOLOPYRIDINE;PHOP;CAY10402;1-([1,3]oxazolo[4,5-b]pyridin-2-yl)-6-phenylhexan-1-one;1-Hexanone, 1-oxazolo[4,5-b]pyridin-2-yl-6-phenyl-;1-Oxazolo[4,5-b]pyridin-2-yl-6-phenylhexan-1-one
5 prices
Selected condition：
Brand
- AK Scientific
- Cayman Chemical
Package
- 100μg
- 500μg
- 1mg
- 5mg
- ManufacturerAK Scientific
- Product number5499CR
- Product description1-Oxazolo[4,5-b]pyridin-2-yl-6-phenyl-hexan-1-one
- Packaging1mg
- Price$402
- Updated2021-12-16
- Buy
- ManufacturerCayman Chemical
- Product number71655
- Product descriptionPHOP ≥98%
- Packaging1mg
- Price$432
- Updated2026-04-30
- Buy
- ManufacturerCayman Chemical
- Product number71655
- Product descriptionPHOP ≥98%
- Packaging5mg
- Price$1887
- Updated2026-04-30
- Buy
- ManufacturerCayman Chemical
- Product number71655
- Product descriptionPHOP ≥98%
- Packaging100μg
- Price$54
- Updated2026-04-30
- Buy
- ManufacturerCayman Chemical
- Product number71655
- Product descriptionPHOP ≥98%
- Packaging500μg
- Price$244
- Updated2026-04-30
- Buy
| Manufacturer | Product number | Product description | Packaging | Price | Updated | Buy |
|---|---|---|---|---|---|---|
| AK Scientific | 5499CR | 1-Oxazolo[4,5-b]pyridin-2-yl-6-phenyl-hexan-1-one | 1mg | $402 | 2021-12-16 | Buy |
| Cayman Chemical | 71655 | PHOP ≥98% | 1mg | $432 | 2026-04-30 | Buy |
| Cayman Chemical | 71655 | PHOP ≥98% | 5mg | $1887 | 2026-04-30 | Buy |
| Cayman Chemical | 71655 | PHOP ≥98% | 100μg | $54 | 2026-04-30 | Buy |
| Cayman Chemical | 71655 | PHOP ≥98% | 500μg | $244 | 2026-04-30 | Buy |
Properties
Boiling point :460.8±47.0 °C(Predicted)
Density :1.172±0.06 g/cm3(Predicted)
storage temp. :-20°C
solubility :DMF: 30 mg/ml; DMSO: 30 mg/ml; DMSO:PBS (pH 7.2)(1:2): .25 mg/ml; Ethanol: 10 mg/ml
form :solid
pka :-1.77±0.50(Predicted)
InChI :1S/2C18H18N2O2/c2*21-15(18-20-17-16(22-18)12-7-13-19-17)11-6-2-5-10-14-8-3-1-4-9-14/h2*1,3-4,7-9,12-13H,2,5-6,10-11H2
InChIKey :LFAKEBRRAYWLPI-UHFFFAOYSA-N
SMILES :O=C(C1=NC2=C(C=CC=N2)O1)CCCCCC3=CC=CC=C3
Density :1.172±0.06 g/cm3(Predicted)
storage temp. :-20°C
solubility :DMF: 30 mg/ml; DMSO: 30 mg/ml; DMSO:PBS (pH 7.2)(1:2): .25 mg/ml; Ethanol: 10 mg/ml
form :solid
pka :-1.77±0.50(Predicted)
InChI :1S/2C18H18N2O2/c2*21-15(18-20-17-16(22-18)12-7-13-19-17)11-6-2-5-10-14-8-3-1-4-9-14/h2*1,3-4,7-9,12-13H,2,5-6,10-11H2
InChIKey :LFAKEBRRAYWLPI-UHFFFAOYSA-N
SMILES :O=C(C1=NC2=C(C=CC=N2)O1)CCCCCC3=CC=CC=C3
Safety Information
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| Signal word: | Warning | ||||||||||||||
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Description
Fatty acid amide hydrolase (FAAH) is the enzyme responsible for hydrolysis and inactivation of fatty acid amides including anandamide and oleamide. PHOP is a potent FAAH inhibitor, exhibiting Ki values of 0.094 nM and 0.2 nM for the human and rat enzymes, respectively. Using a proteomics approach, PHOP was screened against the serine hydrolase family of enzymes, of which FAAH is a member. In this assay, PHOP exhibited IC50 values of 1.1 nM, 1.4 nM, and >100 μM for FAAH, triacylglycerol hydrolase (TGH), and an uncharacterized hydrolase (KIAA1363), respectively. Knowledge of the specificity of PHOP obtained from this experiment should allow for more accurate interpretation of results using this inhibitor in complex environments such as whole cells or animals.Related product price
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