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ChemicalBook >> CAS DataBase List >> (S)-(+)-alpha-Methoxy-alpha-trifluoromethylphenylacetyl chloride

(S)-(+)-alpha-Methoxy-alpha-trifluoromethylphenylacetyl chloride

(S)-(+)-alpha-Methoxy-alpha-trifluoromethylphenylacetyl chloride price.
  • $38 - $2480
  • Product name: (S)-(+)-alpha-Methoxy-alpha-trifluoromethylphenylacetyl chloride
  • CAS: 39637-99-5
  • MF: C10H8ClF3O2
  • MW: 252.62
  • EINECS:621-758-4
  • MDL Number:MFCD00044400
  • Synonyms:(R)-(fi)-alpha-methoxy-alpha-trifluoromethylphenylacetylchloride ;(R)-(-)-alpha-Methoxy-alpha-(trifluoromethyl)phenylacetyl chloride, 98+%;(R)-(-)-MTPA-Cl, Moshers acid chloride;(S)-2-Methoxy-2-phenyl-3,3,3-trifluoropropionic acid chloride;(S)-2-Methoxy-3,3,3-trifluoro-2-phenylpropionic acid chloride;(S)-2-Phenyl-2-methoxy-3,3,3-trifluoropropionic acid chloride;[S,(+)]-α-Methoxy-α-(trifluoromethyl)benzeneacetic acid chloride;(R)-(-)-^a-Methoxy-^a-(trifluoromethyl)phenylacetyl chloride, 98+%
Price42 Properties Safety Information Description
42 prices
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Brand
  • aablocks
  • Alichem
  • American Custom Chemicals Corporation
  • Apolloscientific
  • Biosynth
  • Chem-Impex
  • Crysdot
  • Matrix Scientific
  • Sigma-Aldrich
  • SynQuest Laboratories
  • TCI Chemical
  • Thermo Scientific Chemicals
  • TRC
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  • 250MG
  • 0.25g
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  • 1g
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  • 5g
  • Manufactureraablocks
  • Product numberAA003CEV
  • Product description(R)-(-)-α-Methoxy-α-(trifluoromethyl)phenylacetyl chloride 97%
  • Packaging50mg
  • Price$38
  • Updated2026-05-28
  • Buy
  • Manufactureraablocks
  • Product numberAA003CEV
  • Product description(R)-(-)-α-Methoxy-α-(trifluoromethyl)phenylacetyl chloride >98.0%(GC)(T)
  • Packaging100mg
  • Price$44
  • Updated2026-05-28
  • Buy
  • Manufactureraablocks
  • Product numberAA003CEV
  • Product description(R)-(-)-α-Methoxy-α-(trifluoromethyl)phenylacetyl chloride
  • Packaging5g
  • Price$258
  • Updated2026-05-28
  • Buy
  • ManufacturerAlichem
  • Product number39637995
  • Product description(-)-alpha-Methoxy-alpha-(trifluoromethyl)phenylacetylchloride
  • Packaging1g
  • Price$1768.8
  • Updated2021-12-16
  • Buy
  • ManufacturerAmerican Custom Chemicals Corporation
  • Product numberCCH0040435
  • Product description(R)-(-)-ALPHA-METHOXY-ALPHA-(TRIFLUOROMETHYL)PHENYLACETYL CHLORIDE 95.00%
  • Packaging5G
  • Price$1449.29
  • Updated2021-12-16
  • Buy
  • ManufacturerAmerican Custom Chemicals Corporation
  • Product numberCCH0040435
  • Product description(R)-(-)-ALPHA-METHOXY-ALPHA-(TRIFLUOROMETHYL)PHENYLACETYL CHLORIDE 95.00%
  • Packaging250MG
  • Price$708.48
  • Updated2021-12-16
  • Buy
  • ManufacturerAmerican Custom Chemicals Corporation
  • Product numberCCH0040435
  • Product description(R)-(-)-ALPHA-METHOXY-ALPHA-(TRIFLUOROMETHYL)PHENYLACETYL CHLORIDE 95.00%
  • Packaging1G
  • Price$810.35
  • Updated2021-12-16
  • Buy
  • ManufacturerApolloscientific
  • Product numberPC5063L
  • Product description(2R)-(-)-2-Methoxy-2-phenyl-3,3,3-trifluoropropanoyl chloride 99%
  • Packaging5g
  • Price$857
  • Updated2026-06-04
  • Buy
  • ManufacturerApolloscientific
  • Product numberPC57487
  • Product description(R)-(-)-a-Methoxy-a-trifluoromethylphenylacetyl chloride, ca. 18% solution in Dichloromethane (ca. 1.0mol/L) 97%
  • Packaging250mg
  • Price$196
  • Updated2026-06-04
  • Buy
  • ManufacturerApolloscientific
  • Product numberPC57487
  • Product description(R)-(-)-a-Methoxy-a-trifluoromethylphenylacetyl chloride, ca. 18% solution in Dichloromethane (ca. 1.0mol/L) 97%
  • Packaging1g
  • Price$527
  • Updated2026-06-04
  • Buy
  • ManufacturerApolloscientific
  • Product numberPC57487
  • Product description(R)-(-)-a-Methoxy-a-trifluoromethylphenylacetyl chloride, ca. 18% solution in Dichloromethane (ca. 1.0mol/L) 97%
  • Packaging50mg
  • Price$59
  • Updated2026-06-04
  • Buy
  • ManufacturerApolloscientific
  • Product numberPC5063L
  • Product description(2R)-(-)-2-Methoxy-2-phenyl-3,3,3-trifluoropropanoyl chloride 99%
  • Packaging250mg
  • Price$79
  • Updated2026-06-04
  • Buy
  • ManufacturerApolloscientific
  • Product numberPC57487
  • Product description(R)-(-)-a-Methoxy-a-trifluoromethylphenylacetyl chloride, ca. 18% solution in Dichloromethane (ca. 1.0mol/L) 97%
  • Packaging100mg
  • Price$98
  • Updated2026-06-04
  • Buy
  • ManufacturerApolloscientific
  • Product numberPC5063L
  • Product description(2R)-(-)-2-Methoxy-2-phenyl-3,3,3-trifluoropropanoyl chloride 99%
  • Packaging1g
  • Price$177
  • Updated2026-06-04
  • Buy
  • ManufacturerApolloscientific
  • Product numberPC57487
  • Product description(R)-(-)-a-Methoxy-a-trifluoromethylphenylacetyl chloride, ca. 18% solution in Dichloromethane (ca. 1.0mol/L) 97%
  • Packaging5g
  • Price$2480
  • Updated2026-06-04
  • Buy
  • ManufacturerBiosynth
  • Product numberFT105924
  • Product description(R)-(-)-α-Methoxy-α-(trifluoromethyl)phenylacetyl chloride
  • Packaging0.1g
  • Price$900
  • Updated2026-06-04
  • Buy
Manufacturer Product number Product description Packaging Price Updated Buy
aablocks AA003CEV (R)-(-)-α-Methoxy-α-(trifluoromethyl)phenylacetyl chloride 97% 50mg $38 2026-05-28 Buy
aablocks AA003CEV (R)-(-)-α-Methoxy-α-(trifluoromethyl)phenylacetyl chloride >98.0%(GC)(T) 100mg $44 2026-05-28 Buy
aablocks AA003CEV (R)-(-)-α-Methoxy-α-(trifluoromethyl)phenylacetyl chloride 5g $258 2026-05-28 Buy
Alichem 39637995 (-)-alpha-Methoxy-alpha-(trifluoromethyl)phenylacetylchloride 1g $1768.8 2021-12-16 Buy
American Custom Chemicals Corporation CCH0040435 (R)-(-)-ALPHA-METHOXY-ALPHA-(TRIFLUOROMETHYL)PHENYLACETYL CHLORIDE 95.00% 5G $1449.29 2021-12-16 Buy
American Custom Chemicals Corporation CCH0040435 (R)-(-)-ALPHA-METHOXY-ALPHA-(TRIFLUOROMETHYL)PHENYLACETYL CHLORIDE 95.00% 250MG $708.48 2021-12-16 Buy
American Custom Chemicals Corporation CCH0040435 (R)-(-)-ALPHA-METHOXY-ALPHA-(TRIFLUOROMETHYL)PHENYLACETYL CHLORIDE 95.00% 1G $810.35 2021-12-16 Buy
Apolloscientific PC5063L (2R)-(-)-2-Methoxy-2-phenyl-3,3,3-trifluoropropanoyl chloride 99% 5g $857 2026-06-04 Buy
Apolloscientific PC57487 (R)-(-)-a-Methoxy-a-trifluoromethylphenylacetyl chloride, ca. 18% solution in Dichloromethane (ca. 1.0mol/L) 97% 250mg $196 2026-06-04 Buy
Apolloscientific PC57487 (R)-(-)-a-Methoxy-a-trifluoromethylphenylacetyl chloride, ca. 18% solution in Dichloromethane (ca. 1.0mol/L) 97% 1g $527 2026-06-04 Buy
Apolloscientific PC57487 (R)-(-)-a-Methoxy-a-trifluoromethylphenylacetyl chloride, ca. 18% solution in Dichloromethane (ca. 1.0mol/L) 97% 50mg $59 2026-06-04 Buy
Apolloscientific PC5063L (2R)-(-)-2-Methoxy-2-phenyl-3,3,3-trifluoropropanoyl chloride 99% 250mg $79 2026-06-04 Buy
Apolloscientific PC57487 (R)-(-)-a-Methoxy-a-trifluoromethylphenylacetyl chloride, ca. 18% solution in Dichloromethane (ca. 1.0mol/L) 97% 100mg $98 2026-06-04 Buy
Apolloscientific PC5063L (2R)-(-)-2-Methoxy-2-phenyl-3,3,3-trifluoropropanoyl chloride 99% 1g $177 2026-06-04 Buy
Apolloscientific PC57487 (R)-(-)-a-Methoxy-a-trifluoromethylphenylacetyl chloride, ca. 18% solution in Dichloromethane (ca. 1.0mol/L) 97% 5g $2480 2026-06-04 Buy
Biosynth FT105924 (R)-(-)-α-Methoxy-α-(trifluoromethyl)phenylacetyl chloride 0.1g $900 2026-06-04 Buy
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Properties

Boiling point :213-214 °C(lit.)
alpha :D25 -10.0± 0.1° (neat, l = 1)
Density :1.35 g/mL at 25 °C(lit.)
refractive index :n20/D 1.469(lit.)
Flash point :194 °F
storage temp. :Inert atmosphere,Store in freezer, under -20°C
form :Liquid
color :Clear colorless to light yellow
Specific Gravity :1.353
optical activity :[α]20/D 137±2°, c = 6.4% in carbon tetrachloride
Water Solubility :Sparingly miscible with water.
Sensitive :Moisture Sensitive
Merck :14,6280
BRN :3591565
InChI :1S/C10H8ClF3O2/c1-16-9(8(11)15,10(12,13)14)7-5-3-2-4-6-7/h2-6H,1H3/t9-/m0/s1
InChIKey :PAORVUMOXXAMPL-VIFPVBQESA-N
SMILES :CO[C@](C(Cl)=O)(c1ccccc1)C(F)(F)F
CAS DataBase Reference :39637-99-5(CAS DataBase Reference)

Safety Information

Symbol(GHS): Corrosion (GHS05)
Signal word: Danger
Hazard statements:
Code Hazard statements Hazard class Category Signal word Pictogram P-Codes
H314 Causes severe skin burns and eye damage Skin corrosion/irritation Category 1A, B, C Danger P260,P264, P280, P301+P330+ P331,P303+P361+P353, P363, P304+P340,P310, P321, P305+ P351+P338, P405,P501
Precautionary statements:
P280 Wear protective gloves/protective clothing/eye protection/face protection.
P301+P330+P331 IF SWALLOWED: Rinse mouth. Do NOT induce vomiting.
P303+P361+P353 IF ON SKIN (or hair): Remove/Take off Immediately all contaminated clothing. Rinse SKIN with water/shower.
P305+P351+P338 IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continuerinsing.
P363 Wash contaminated clothing before reuse.

Description

(R)-(-)-α-Methoxy-α-(trifluoromethyl)phenylacetyl chloride is used as a chiral acylating reagent, which is used in the resolution of amino acid enantiomers like 2,5-dimethoxy-4-methylamphetamine. It is also suitable for the determination of the optical composition of compounds extracted from biological fluids.

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Suppliers and manufacturers

J & K SCIENTIFIC LTD. Meryer (Shanghai) Chemical Technology Co., Ltd. Alfa Aesar TCI (Shanghai) Development Co., Ltd. Energy Chemical Shanghai Longsheng chemical Co.,Ltd. Shandong Xiya Chemical Co., Ltd Sinopharm Chemical Reagent Co,Ltd. Tianjin Derchemist Science & Technology Co., Ltd. Chengdu Ai Keda Chemical Technology Co., Ltd.