(Z,E)-5-(4-Ethylbenzylidine)-2-thioxothiazolidin-4-one
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- $19 - $1654.1
- Product name: (Z,E)-5-(4-Ethylbenzylidine)-2-thioxothiazolidin-4-one
- CAS: 403811-55-2
- MF: C12H11NOS2
- MW: 249.35
- EINECS:
- MDL Number:MFCD00758517
- Synonyms:(5E)-5-[(4-ethylphenyl)methylidene]-2-sulfanylidene-1,3-thiazolidin-4-one;c-Myc Inhibitor;ZINC01085340;CS-1512;5-[(4-Ethylphenyl)methylene]-2-thioxo-4-thiazolidinone;(5E)-5-(4-ethylbenzylidene)-2-mercapto-1,3-thiazol-4(5H)-one;Albb-009118;(5E)-5-(4-ethylbenzylidene)-2-mercapto-1,3-thiazol-4(5H)-one(SALTDATA: FREE)
83 prices
Selected condition：
Brand
- aablocks
- Adipogen Life Sciences
- AK Scientific
- American Custom Chemicals Corporation
- ApexBio Technology
- Apolloscientific
- Arctom
- Atlantic Research Chemicals
- AvaChem
- Axon Medchem
- Biorbyt Ltd
- Cayman Chemical
- ChemBridge Corporation
- ChemScene
- Crysdot
- DC Chemicals
- Matrix Scientific
- Medical Isotopes, Inc.
- Sigma-Aldrich
- TCI Chemical
- Thermo Scientific Chemicals
- TRC
- Usbiological
Package
- 10mM(in 1mL DMSO)
- 1mg
- 10mM(in1mLDMSO)
- 5mg
- 10mg
- 10.00mg
- 20mg
- 25mg
- 50mg
- 50.00mg
- 100mg
- 100.00mg
- 250mg
- 0.5G
- 500mg
- 1000mg
- 1g
- 5g
- 10g
- Manufactureraablocks
- Product numberAA00732T
- Product description10058-F4 98+%
- Packaging1mg
- Price$19
- Updated2026-05-28
- Buy
- Manufactureraablocks
- Product numberAA00732T
- Product description10058-F4 99%
- Packaging5mg
- Price$32
- Updated2026-05-28
- Buy
- Manufactureraablocks
- Product numberAA00732T
- Product description10058-F4 99%
- Packaging10mg
- Price$43
- Updated2026-05-28
- Buy
- Manufactureraablocks
- Product numberAA00732T
- Product description10058-F4 99%
- Packaging50mg
- Price$52
- Updated2026-05-28
- Buy
- Manufactureraablocks
- Product numberAA00732T
- Product description10058-F4 99%
- Packaging100mg
- Price$62
- Updated2026-05-28
- Buy
- Manufactureraablocks
- Product numberAA00732T
- Product description10058-F4 95%
- Packaging250mg
- Price$63
- Updated2026-05-28
- Buy
- Manufactureraablocks
- Product numberAA00732T
- Product description10058-F4 95%
- Packaging1g
- Price$86
- Updated2026-05-28
- Buy
- Manufactureraablocks
- Product numberAA00732T
- Product description10058-F4 95%
- Packaging5g
- Price$343
- Updated2026-05-28
- Buy
- Manufactureraablocks
- Product numberAA00732T
- Product description10058-F4 95%
- Packaging10g
- Price$629
- Updated2026-05-28
- Buy
- ManufacturerAdipogen Life Sciences
- Product numberCDX-E0533-M025
- Product description5-[(4-Ethylphenyl)methylene]-2-thioxo-4-thiazolidinone ≥95%(NMR)
- Packaging25mg
- Price$158
- Updated2026-05-06
- Buy
- ManufacturerAdipogen Life Sciences
- Product numberCDX-E0533-M005
- Product description5-[(4-Ethylphenyl)methylene]-2-thioxo-4-thiazolidinone ≥95%(NMR)
- Packaging5mg
- Price$53
- Updated2026-05-06
- Buy
- ManufacturerAK Scientific
- Product numberZ6200
- Product description(E)-5-(4-Ethylbenzylidene)-2-thioxothiazolidin-4-one
- Packaging500mg
- Price$152
- Updated2021-12-16
- Buy
- ManufacturerAK Scientific
- Product numberZ6200
- Product description(E)-5-(4-Ethylbenzylidene)-2-thioxothiazolidin-4-one
- Packaging1g
- Price$207
- Updated2021-12-16
- Buy
- ManufacturerAmerican Custom Chemicals Corporation
- Product numberINB0004449
- Product description10058-F4 95.00%
- Packaging0.5G
- Price$605
- Updated2021-12-16
- Buy
- ManufacturerApexBio Technology
- Product numberA1169
- Product description10058-F4
- Packaging50mg
- Price$220
- Updated2026-05-06
- Buy
- ManufacturerApexBio Technology
- Product numberA1169
- Product description10058-F4
- Packaging10mM(in1mLDMSO)
- Price$61
- Updated2026-05-06
- Buy
| Manufacturer | Product number | Product description | Packaging | Price | Updated | Buy |
|---|---|---|---|---|---|---|
| aablocks | AA00732T | 10058-F4 98+% | 1mg | $19 | 2026-05-28 | Buy |
| aablocks | AA00732T | 10058-F4 99% | 5mg | $32 | 2026-05-28 | Buy |
| aablocks | AA00732T | 10058-F4 99% | 10mg | $43 | 2026-05-28 | Buy |
| aablocks | AA00732T | 10058-F4 99% | 50mg | $52 | 2026-05-28 | Buy |
| aablocks | AA00732T | 10058-F4 99% | 100mg | $62 | 2026-05-28 | Buy |
| aablocks | AA00732T | 10058-F4 95% | 250mg | $63 | 2026-05-28 | Buy |
| aablocks | AA00732T | 10058-F4 95% | 1g | $86 | 2026-05-28 | Buy |
| aablocks | AA00732T | 10058-F4 95% | 5g | $343 | 2026-05-28 | Buy |
| aablocks | AA00732T | 10058-F4 95% | 10g | $629 | 2026-05-28 | Buy |
| Adipogen Life Sciences | CDX-E0533-M025 | 5-[(4-Ethylphenyl)methylene]-2-thioxo-4-thiazolidinone ≥95%(NMR) | 25mg | $158 | 2026-05-06 | Buy |
| Adipogen Life Sciences | CDX-E0533-M005 | 5-[(4-Ethylphenyl)methylene]-2-thioxo-4-thiazolidinone ≥95%(NMR) | 5mg | $53 | 2026-05-06 | Buy |
| AK Scientific | Z6200 | (E)-5-(4-Ethylbenzylidene)-2-thioxothiazolidin-4-one | 500mg | $152 | 2021-12-16 | Buy |
| AK Scientific | Z6200 | (E)-5-(4-Ethylbenzylidene)-2-thioxothiazolidin-4-one | 1g | $207 | 2021-12-16 | Buy |
| American Custom Chemicals Corporation | INB0004449 | 10058-F4 95.00% | 0.5G | $605 | 2021-12-16 | Buy |
| ApexBio Technology | A1169 | 10058-F4 | 50mg | $220 | 2026-05-06 | Buy |
| ApexBio Technology | A1169 | 10058-F4 | 10mM(in1mLDMSO) | $61 | 2026-05-06 | Buy |
Properties
Density :1.33±0.1 g/cm3(Predicted)
storage temp. :2-8°C
solubility :DMSO: >10mg/mL
pka :7.72±0.30(Predicted)
form :Yellow solid
color :yellow
Water Solubility :Soluble in DMSO. Soluble in water at concentrations less than 2mg/ml
Stability :Stable for 1 year from date of purchase as supplied. Solutions in DMSO or ethanol may be stored at -20° for up to 1 month.
InChI :1S/C12H11NOS2/c1-2-8-3-5-9(6-4-8)7-10-11(14)13-12(15)16-10/h3-7H,2H2,1H3,(H,13,14,15)/b10-7+
InChIKey :SVXDHPADAXBMFB-JXMROGBWSA-N
SMILES :CCc1ccc(cc1)\C=C2\SC(=S)NC2=O
storage temp. :2-8°C
solubility :DMSO: >10mg/mL
pka :7.72±0.30(Predicted)
form :Yellow solid
color :yellow
Water Solubility :Soluble in DMSO. Soluble in water at concentrations less than 2mg/ml
Stability :Stable for 1 year from date of purchase as supplied. Solutions in DMSO or ethanol may be stored at -20° for up to 1 month.
InChI :1S/C12H11NOS2/c1-2-8-3-5-9(6-4-8)7-10-11(14)13-12(15)16-10/h3-7H,2H2,1H3,(H,13,14,15)/b10-7+
InChIKey :SVXDHPADAXBMFB-JXMROGBWSA-N
SMILES :CCc1ccc(cc1)\C=C2\SC(=S)NC2=O
Safety Information
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| Signal word: | Warning | |||||||||||||||||||||
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Description
The Myc proto-oncogenes interact with Max to form a dimer that regulates gene transcription. The protein c-Myc, in particular, promotes gene expression relevant to cell growth and thus drives cancer. 10058-F4 is a cell-permeable thiazolidinone that inhibits the dimerization of c-Myc and Max at 64 μM, preventing c-Myc-dependent gene expression and cell proliferation. It induces cell cycle arrest, apoptosis, and myeloid differentiation at 100 μM in human acute myeloid leukemia cells. 10058-F4 is rapidly metabolized in mice when given intravenously, limiting its effects on tumors in vivo. In addition to c-Myc, 10058-F4 inhibits the nuclear Myc protein, N-Myc, at 50 μM, inducing arrest, apoptosis, and differentiation in neuroblastoma cells overexpressing the gene for N-Myc. This compound can be used to delineate novel actions of Myc proteins, especially those related to lipid and glucose metabolism.More related product prices
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Suppliers and manufacturers
Shanghai Boyle Chemical Co., Ltd.
J & K SCIENTIFIC LTD.
Chembest Research Laboratories Limited
TCI (Shanghai) Development Co., Ltd.
Wuhan Chemwish Technology Co., Ltd
Jinan Trio PharmaTech Co., Ltd.
Dalian Meilun Biotech Co., Ltd.
Haoyuan Chemexpress Co., Ltd.
TOKYO CHEMICAL INDUSTRY CO., LTD.
TCI Europe