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ChemicalBook >> CAS DataBase List >> Bortezomib

Bortezomib

Bortezomib price.
  • $10 - $2516.45
  • Product name: Bortezomib
  • CAS: 179324-69-7
  • MF: C19H25BN4O4
  • MW: 384.24
  • EINECS:605-854-3
  • MDL Number:MFCD09056737
  • Synonyms:Boronic acid, B-[(1R)-3-Methyl-1-[[(2S)-1-oxo-3-phenyl-2-[(2-pyrazinylcarbonyl)aMino]propyl]aMino]bu;MG-341 PS-341;BortezoMib Base;bortezoMib(other);MLM341;BortezoMib R;VELCADE(BORTEZOMIB);Boronic acid, B-[(1R)-3-methyl-1-[[(2S)-1-oxo-3-phenyl-2-[(2-pyrazinylcarbonyl)amino]propyl]amino]butyl]-
129 prices
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Brand
  • aablocks
  • ACHEMBLOCK
  • Adipogen Life Sciences
  • AK Scientific
  • Alichem
  • Ambeed
  • American Custom Chemicals Corporation
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  • JR MediChem
  • Matrix Scientific
  • Medical Isotopes, Inc.
  • Sigma-Aldrich
  • TCI Chemical
  • Thermo Scientific Chemicals
  • Tocris
  • TRC
  • Usbiological
Package
  • 1mg
  • 1unit
  • 10mM*1mLinDMSO
  • 20mg
  • 0.25g
  • 200mg
  • 5
  • 0.5g
  • 2g
  • 10g
  • 25g
  • 100??g
  • 5mg
  • 10mg
  • 25mg
  • 50mg
  • 100mg
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  • 500mg
  • EvaluationSample
  • 5G
  • 10mM(in1mLDMSO)
  • 1g
  • 10mM(in 1mL DMSO)
  • Manufactureraablocks
  • Product numberAA0026UO
  • Product description[(1R)-3-Methyl-1-[[(2S)-1-oxo-3-phenyl-2-[(pyrazinylcarbonyl)amino]propyl]amino]butyl]boronic acid 98%
  • Packaging1g
  • Price$87
  • Updated2026-05-28
  • Buy
  • Manufactureraablocks
  • Product numberAA0026UO
  • Product description[(1R)-3-Methyl-1-[[(2S)-1-oxo-3-phenyl-2-[(pyrazinylcarbonyl)amino]propyl]amino]butyl]boronic acid 98%
  • Packaging250mg
  • Price$31
  • Updated2026-05-28
  • Buy
  • Manufactureraablocks
  • Product numberAA0026UO
  • Product description[(1R)-3-Methyl-1-[[(2S)-1-oxo-3-phenyl-2-[(pyrazinylcarbonyl)amino]propyl]amino]butyl]boronic acid 98%
  • Packaging100mg
  • Price$23
  • Updated2026-05-28
  • Buy
  • Manufactureraablocks
  • Product numberAA0026UO
  • Product description[(1R)-3-Methyl-1-[[(2S)-1-oxo-3-phenyl-2-[(pyrazinylcarbonyl)amino]propyl]amino]butyl]boronic acid 98%
  • Packaging50mg
  • Price$19
  • Updated2026-05-28
  • Buy
  • Manufactureraablocks
  • Product numberAA0026UO
  • Product description[(1R)-3-Methyl-1-[[(2S)-1-oxo-3-phenyl-2-[(pyrazinylcarbonyl)amino]propyl]amino]butyl]boronic acid ≥98%
  • Packaging25mg
  • Price$18
  • Updated2026-05-28
  • Buy
  • Manufactureraablocks
  • Product numberAA0026UO
  • Product description[(1R)-3-Methyl-1-[[(2S)-1-oxo-3-phenyl-2-[(pyrazinylcarbonyl)amino]propyl]amino]butyl]boronic acid ≥98%
  • Packaging5mg
  • Price$10
  • Updated2026-05-28
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  • ManufacturerACHEMBLOCK
  • Product numberG-7278
  • Product descriptionBortezomib 98%
  • Packaging100MG
  • Price$40
  • Updated2026-05-27
  • Buy
  • ManufacturerACHEMBLOCK
  • Product numberG-7278
  • Product descriptionBortezomib 98%
  • Packaging5G
  • Price$545
  • Updated2026-05-27
  • Buy
  • ManufacturerACHEMBLOCK
  • Product numberG-7278
  • Product descriptionBortezomib 98%
  • Packaging1G
  • Price$180
  • Updated2026-05-27
  • Buy
  • ManufacturerAdipogen Life Sciences
  • Product numberAG-CR1-3602-M025
  • Product descriptionBortezomib ≥97%(NMR)
  • Packaging25mg
  • Price$70
  • Updated2026-05-06
  • Buy
  • ManufacturerAdipogen Life Sciences
  • Product numberAG-CR1-3602-M005
  • Product descriptionBortezomib ≥97%(NMR)
  • Packaging5mg
  • Price$55
  • Updated2026-05-06
  • Buy
  • ManufacturerAdipogen Life Sciences
  • Product numberAG-CR1-3602-M005
  • Product descriptionBortezomib ≥97%(NMR)
  • Packaging5mg
  • Price$50
  • Updated2021-12-16
  • Buy
  • ManufacturerAK Scientific
  • Product numberQ425
  • Product descriptionBortezomib 98%,powder
  • Packaging10mg
  • Price$28
  • Updated2026-06-04
  • Buy
  • ManufacturerAK Scientific
  • Product numberQ425
  • Product descriptionBortezomib 98%,powder
  • Packaging100mg
  • Price$150
  • Updated2026-06-04
  • Buy
  • ManufacturerAK Scientific
  • Product numberQ425
  • Product descriptionBortezomib
  • Packaging5mg
  • Price$60
  • Updated2021-12-16
  • Buy
  • ManufacturerAlichem
  • Product number179324697
  • Product description((R)-3-Nethyl-1-((S)-3-phenyl-2-(pyrazine-2-carboxamido)propanamido)butyl)boronicacid
  • Packaging1g
  • Price$468.3
  • Updated2021-12-16
  • Buy
Manufacturer Product number Product description Packaging Price Updated Buy
aablocks AA0026UO [(1R)-3-Methyl-1-[[(2S)-1-oxo-3-phenyl-2-[(pyrazinylcarbonyl)amino]propyl]amino]butyl]boronic acid 98% 1g $87 2026-05-28 Buy
aablocks AA0026UO [(1R)-3-Methyl-1-[[(2S)-1-oxo-3-phenyl-2-[(pyrazinylcarbonyl)amino]propyl]amino]butyl]boronic acid 98% 250mg $31 2026-05-28 Buy
aablocks AA0026UO [(1R)-3-Methyl-1-[[(2S)-1-oxo-3-phenyl-2-[(pyrazinylcarbonyl)amino]propyl]amino]butyl]boronic acid 98% 100mg $23 2026-05-28 Buy
aablocks AA0026UO [(1R)-3-Methyl-1-[[(2S)-1-oxo-3-phenyl-2-[(pyrazinylcarbonyl)amino]propyl]amino]butyl]boronic acid 98% 50mg $19 2026-05-28 Buy
aablocks AA0026UO [(1R)-3-Methyl-1-[[(2S)-1-oxo-3-phenyl-2-[(pyrazinylcarbonyl)amino]propyl]amino]butyl]boronic acid ≥98% 25mg $18 2026-05-28 Buy
aablocks AA0026UO [(1R)-3-Methyl-1-[[(2S)-1-oxo-3-phenyl-2-[(pyrazinylcarbonyl)amino]propyl]amino]butyl]boronic acid ≥98% 5mg $10 2026-05-28 Buy
ACHEMBLOCK G-7278 Bortezomib 98% 100MG $40 2026-05-27 Buy
ACHEMBLOCK G-7278 Bortezomib 98% 5G $545 2026-05-27 Buy
ACHEMBLOCK G-7278 Bortezomib 98% 1G $180 2026-05-27 Buy
Adipogen Life Sciences AG-CR1-3602-M025 Bortezomib ≥97%(NMR) 25mg $70 2026-05-06 Buy
Adipogen Life Sciences AG-CR1-3602-M005 Bortezomib ≥97%(NMR) 5mg $55 2026-05-06 Buy
Adipogen Life Sciences AG-CR1-3602-M005 Bortezomib ≥97%(NMR) 5mg $50 2021-12-16 Buy
AK Scientific Q425 Bortezomib 98%,powder 10mg $28 2026-06-04 Buy
AK Scientific Q425 Bortezomib 98%,powder 100mg $150 2026-06-04 Buy
AK Scientific Q425 Bortezomib 5mg $60 2021-12-16 Buy
Alichem 179324697 ((R)-3-Nethyl-1-((S)-3-phenyl-2-(pyrazine-2-carboxamido)propanamido)butyl)boronicacid 1g $468.3 2021-12-16 Buy

Properties

Melting point :122-124°C
Density :1.214
RTECS :ED7771666
storage temp. :Inert atmosphere,Store in freezer, under -20°C
solubility :Soluble in chloroform, dimethyl sulfoxide, ethanol and methanol.
pka :9.66±0.43(Predicted)
form :solid
color :White
optical activity :Consistent with structure
Stability :Hygroscopic and Moisture Sensitive
InChIKey :GXJABQQUPOEUTA-RDJZCZTQSA-N
SMILES :B([C@@H](NC(=O)[C@@H](NC(C1=NC=CN=C1)=O)CC1=CC=CC=C1)CC(C)C)(O)O
CAS DataBase Reference :179324-69-7(CAS DataBase Reference)

Safety Information

Symbol(GHS): Skull and Crossbones (GHS06)Health Hazard (GHS08)
Signal word: Danger
Hazard statements:
Code Hazard statements Hazard class Category Signal word Pictogram P-Codes
H300 Fatal if swallowed Acute toxicity,oral Category 1, 2 Danger P264, P270, P301+P310, P321, P330,P405, P501
H310 Fatal in contact with skin Acute toxicity,dermal Category 1, 2 Danger P262, P264, P270, P280, P302+P350,P310, P322, P361, P363, P405, P501
H330 Fatal if inhaled Acute toxicity,inhalation Category 1, 2 Danger P260, P271, P284, P304+P340, P310,P320, P403+P233, P405, P501
H372 Causes damage to organs through prolonged or repeated exposure Specific target organ toxicity, repeated exposure Category 1 Danger P260, P264, P270, P314, P501
Precautionary statements:
P304+P340 IF INHALED: Remove victim to fresh air and Keep at rest in a position comfortable for breathing.
P320 Specific treatment is urgent (see … on this label).
P330 Rinse mouth.
P405 Store locked up.

Description

Bortezomib, a modified dipeptidyl boronic acid, is a therapeutic proteasome inhibitors used for the treatment of cancers. It is indicated for the treatment of relapsed multiple myeloma and mantle cell lymphoma. It is capable of inhibiting the mammalian 26S proteasome, which is important in regulating the intracellular concentration of specific proteins to maintain homeostasis within cells. The disruption of 26S proteasome function disrupts normal cellular homeostasis, leading to cytotoxic effect on various kinds of cancer cells. 

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