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ChemicalBook >> CAS DataBase List >> N-methyl-N-((3R,4R)-4-methylpiperidin-3-yl)-7H-pyrrolo[2,3-d]pyrimidin-4-amine

N-methyl-N-((3R,4R)-4-methylpiperidin-3-yl)-7H-pyrrolo[2,3-d]pyrimidin-4-amine

$19 - $2918
Product name: N-methyl-N-((3R,4R)-4-methylpiperidin-3-yl)-7H-pyrrolo[2,3-d]pyrimidin-4-amine
CAS: 477600-74-1
MF: C13H19N5
MW: 245.32
EINECS:
MDL Number:MFCD09878608
Synonyms:N-methyl-N-((3R,4R)-4-methylpiperidin-3-yl)-7H-pyrrolo[2,3-d]pyrimidin-4-amine;N-Methyl-N-((3R,4R)-4-Methylpiperidin-3-yl)-7HMethylpiperidin-3-yl)-7Hpyrrolo[ 2,3-d]pyriMidin-4-aMine;(3R,4R)-N,4-diMethyl-N-{7H-pyrrolo[2,3-d]pyriMidin-4-yl}piperidin-3-aMine;7H-Pyrrolo[2,3-d]pyriMidin-4-aMine, N-Methyl-N-[(3R,4R)-4-Methyl-3-piperidinyl]-;N-Methyl-N-((3R,4R)-4-Methyl-piperidin-3-yl)-N-Methyl-7H-pyrrolo[2,3-d]pyriMidin-4-aMine;Tofacitinib-11;Tofacitinib N-Descyanoacetyl;Tofacitinib impurity 7/N-methyl-N-((3R,4R)-4-methylpiperidin-3-yl)-7H-pyrrolo[2,3-d]pyrimidin-4-amine

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AK Scientific
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ManufacturerA2B
Product numberAI50880
Product descriptionN-Methyl-N-((3R,4R)-4-methylpiperidin-3-yl)-7H-pyrrolo[2,3-d]pyrimidin-4-amine 95%
Packaging100mg
Price$19
Updated2026-05-25
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ManufacturerA2B
Product numberAI50880
Product descriptionN-Methyl-N-((3R,4R)-4-methylpiperidin-3-yl)-7H-pyrrolo[2,3-d]pyrimidin-4-amine 95%
Packaging250mg
Price$32
Updated2026-05-25
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ManufacturerA2B
Product numberAI50880
Product descriptionN-Methyl-N-((3R,4R)-4-methylpiperidin-3-yl)-7H-pyrrolo[2,3-d]pyrimidin-4-amine 95%
Packaging1g
Price$57
Updated2026-05-25
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ManufacturerA2B
Product numberAI50880
Product descriptionN-Methyl-N-((3R,4R)-4-methylpiperidin-3-yl)-7H-pyrrolo[2,3-d]pyrimidin-4-amine 95%
Packaging5g
Price$208
Updated2026-05-25
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Manufactureraablocks
Product numberAA00I8MC
Product descriptionN-Methyl-N-((3R,4R)-4-methylpiperidin-3-yl)-7H-pyrrolo[2,3-d]pyrimidin-4-amine 95%
Packaging1g
Price$64
Updated2026-05-29
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Manufactureraablocks
Product numberAA00I8MC
Product descriptionN-Methyl-N-((3R,4R)-4-methylpiperidin-3-yl)-7H-pyrrolo[2,3-d]pyrimidin-4-amine 95%
Packaging250mg
Price$35
Updated2026-05-29
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Manufactureraablocks
Product numberAA00I8MC
Product descriptionN-Methyl-N-((3R,4R)-4-methylpiperidin-3-yl)-7H-pyrrolo[2,3-d]pyrimidin-4-amine ≥95%
Packaging100mg
Price$22
Updated2026-05-29
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Manufactureraablocks
Product numberAA00I8MC
Product descriptionN-Methyl-N-((3R,4R)-4-methylpiperidin-3-yl)-7H-pyrrolo[2,3-d]pyrimidin-4-amine 95%
Packaging5g
Price$231
Updated2026-05-29
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ManufacturerACHEMBLOCK
Product numberA-524
Product descriptionN-Methyl-N-((3R,4R)-4-methylpiperidin-3-yl)-7H-pyrrolo[2,3-d]pyrimidin-4-amine 95%
Packaging5G
Price$210
Updated2026-05-27
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ManufacturerACHEMBLOCK
Product numberA-524
Product descriptionN-Methyl-N-((3R,4R)-4-methylpiperidin-3-yl)-7H-pyrrolo[2,3-d]pyrimidin-4-amine 95%
Packaging25G
Price$520
Updated2026-05-27
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ManufacturerAcrotein
Product numberas02432
Product descriptionN-Methyl-N-[(3R,4R)-4-methylpiperidin-3-yl]-7H-pyrrolo[2,3-d]pyrimidin-4-amine 97%
Packaging10g
Price$779.16
Updated2026-05-25
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ManufacturerAcrotein
Product numberas02432
Product descriptionN-Methyl-N-[(3R,4R)-4-methylpiperidin-3-yl]-7H-pyrrolo[2,3-d]pyrimidin-4-amine 97%
Packaging1g
Price$125.04
Updated2026-05-25
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ManufacturerAcrotein
Product numberas02432
Product descriptionN-Methyl-N-[(3R,4R)-4-methylpiperidin-3-yl]-7H-pyrrolo[2,3-d]pyrimidin-4-amine 97%
Packaging5g
Price$463.84
Updated2026-05-25
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ManufacturerAK Scientific
Product numberX6723
Product descriptionN-Methyl-N-((3R,4R)-4-methylpiperidin-3-yl)-7H-pyrrolo[2,3-d]pyrimidin-4-amine
Packaging100mg
Price$311
Updated2021-12-16
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ManufacturerAmbeed
Product numberA480878
Product descriptionN-Methyl-N-((3R,4R)-4-methylpiperidin-3-yl)-7H-pyrrolo[2,3-d]pyrimidin-4-amine 95%
Packaging5g
Price$322
Updated2021-12-16
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ManufacturerAmbeed
Product numberA480878
Product descriptionN-Methyl-N-((3R,4R)-4-methylpiperidin-3-yl)-7H-pyrrolo[2,3-d]pyrimidin-4-amine 95%
Packaging1g
Price$94
Updated2021-12-16
Buy

Manufacturer	Product number	Product description	Packaging	Price	Updated	Buy
A2B	AI50880	N-Methyl-N-((3R,4R)-4-methylpiperidin-3-yl)-7H-pyrrolo[2,3-d]pyrimidin-4-amine 95%	100mg	$19	2026-05-25	Buy
A2B	AI50880	N-Methyl-N-((3R,4R)-4-methylpiperidin-3-yl)-7H-pyrrolo[2,3-d]pyrimidin-4-amine 95%	250mg	$32	2026-05-25	Buy
A2B	AI50880	N-Methyl-N-((3R,4R)-4-methylpiperidin-3-yl)-7H-pyrrolo[2,3-d]pyrimidin-4-amine 95%	1g	$57	2026-05-25	Buy
A2B	AI50880	N-Methyl-N-((3R,4R)-4-methylpiperidin-3-yl)-7H-pyrrolo[2,3-d]pyrimidin-4-amine 95%	5g	$208	2026-05-25	Buy
aablocks	AA00I8MC	N-Methyl-N-((3R,4R)-4-methylpiperidin-3-yl)-7H-pyrrolo[2,3-d]pyrimidin-4-amine 95%	1g	$64	2026-05-29	Buy
aablocks	AA00I8MC	N-Methyl-N-((3R,4R)-4-methylpiperidin-3-yl)-7H-pyrrolo[2,3-d]pyrimidin-4-amine 95%	250mg	$35	2026-05-29	Buy
aablocks	AA00I8MC	N-Methyl-N-((3R,4R)-4-methylpiperidin-3-yl)-7H-pyrrolo[2,3-d]pyrimidin-4-amine ≥95%	100mg	$22	2026-05-29	Buy
aablocks	AA00I8MC	N-Methyl-N-((3R,4R)-4-methylpiperidin-3-yl)-7H-pyrrolo[2,3-d]pyrimidin-4-amine 95%	5g	$231	2026-05-29	Buy
ACHEMBLOCK	A-524	N-Methyl-N-((3R,4R)-4-methylpiperidin-3-yl)-7H-pyrrolo[2,3-d]pyrimidin-4-amine 95%	5G	$210	2026-05-27	Buy
ACHEMBLOCK	A-524	N-Methyl-N-((3R,4R)-4-methylpiperidin-3-yl)-7H-pyrrolo[2,3-d]pyrimidin-4-amine 95%	25G	$520	2026-05-27	Buy
Acrotein	as02432	N-Methyl-N-[(3R,4R)-4-methylpiperidin-3-yl]-7H-pyrrolo[2,3-d]pyrimidin-4-amine 97%	10g	$779.16	2026-05-25	Buy
Acrotein	as02432	N-Methyl-N-[(3R,4R)-4-methylpiperidin-3-yl]-7H-pyrrolo[2,3-d]pyrimidin-4-amine 97%	1g	$125.04	2026-05-25	Buy
Acrotein	as02432	N-Methyl-N-[(3R,4R)-4-methylpiperidin-3-yl]-7H-pyrrolo[2,3-d]pyrimidin-4-amine 97%	5g	$463.84	2026-05-25	Buy
AK Scientific	X6723	N-Methyl-N-((3R,4R)-4-methylpiperidin-3-yl)-7H-pyrrolo[2,3-d]pyrimidin-4-amine	100mg	$311	2021-12-16	Buy
Ambeed	A480878	N-Methyl-N-((3R,4R)-4-methylpiperidin-3-yl)-7H-pyrrolo[2,3-d]pyrimidin-4-amine 95%	5g	$322	2021-12-16	Buy
Ambeed	A480878	N-Methyl-N-((3R,4R)-4-methylpiperidin-3-yl)-7H-pyrrolo[2,3-d]pyrimidin-4-amine 95%	1g	$94	2021-12-16	Buy

Next Last

Properties

Melting point :157 - 162°C
Density :1+-.0.06 g/cm3(Predicted)
storage temp. :2-8°C(protect from light)
solubility :Aqueous Acid (Slightly), Methanol (Slightly), Water (Slightly, Heated)
form :Solid
pka :13.36±0.50(Predicted)
color :White to Off-White
InChI :InChI=1S/C13H19N5/c1-9-3-5-14-7-11(9)18(2)13-10-4-6-15-12(10)16-8-17-13/h4,6,8-9,11,14H,3,5,7H2,1-2H3,(H,15,16,17)/t9-,11+/m1/s1
InChIKey :XRIARWQZLGCQDM-KOLCDFICSA-N
SMILES :C1=NC(N(C)[C@@H]2[C@H](C)CCNC2)=C2C=CNC2=N1

Safety Information

Symbol(GHS):

Signal word:

Warning

Hazard statements:

Code	Hazard statements	Hazard class	Category	Signal word	Pictogram	P-Codes
H315	Causes skin irritation	Skin corrosion/irritation	Category 2	Warning		P264, P280, P302+P352, P321,P332+P313, P362
H319	Causes serious eye irritation	Serious eye damage/eye irritation	Category 2A	Warning		P264, P280, P305+P351+P338,P337+P313P

Precautionary statements:

P264	Wash hands thoroughly after handling.
P264	Wash skin thouroughly after handling.
P280	Wear protective gloves/protective clothing/eye protection/face protection.
P302+P352	IF ON SKIN: wash with plenty of soap and water.
P305+P351+P338	IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continuerinsing.
P332+P313	IF SKIN irritation occurs: Get medical advice/attention.
P337+P313	IF eye irritation persists: Get medical advice/attention.

Description

N-Methyl-N-((3S,4R)-4-methylpiperidin-3-yl)-7H-pyrrolo[2,3-d]pyrimidin-4-amine, is an intermediate in the synthesis of (3S,4R)-Tofacitinib (T528010), an enantiopure stereoisomer of the drug, Janus kinase 3(Jak3) inhibitor (CP-690,550) that has been found to inhibit selected members of the STE7 and STE20 subfamily of kinases.

More related product prices

CIS-N-BENZYL-3-METHYLAMINO-4-METHYL-PIPERIDINE BIS-(HYDROCHLORIDE) 479633-63-1 7H-Pyrrolo[2,3-d]pyriMidin-4-aMine, N-Methyl-N-[(3R,4R)-4-Methyl-1-(phenylMethyl)-3-piperidinyl]-7-[(4-Met hylphenyl)sulfonyl]- 7H-Pyrrolo[2,3-d]pyriMidin-4-aMine, N-Methyl-N-[(3R,4R)-4-Methyl-1-(phenylMethyl)-3-piperidinyl]- 90213-66-4 3680-69-1 (3R,4R)-1-Benzyl-N,4-dimethylpiperidin-3-amine 1-BENZYL-N,4-DIMETHYLPIPERIDIN-3-AMINE DIHYDROCHLORIDE N-Hydroxysuccinimide 1-Benzyl-4-methyl-piperidin-3-one hydrochloride 6-AMINO-5(2,2-DIETHOXYETHYL)-4-HYDROXY-2-MERCAPTOPYRIMIDINE Benzyl chloride Malonyl chloride 10132-07-7 4-chloro-6,7-dihydro-5H-pyrrolo[2,3-d]pyrimidine BENZYL ETHYL ETHER 6-Amino-5-(2,2-diethoxyethyl)pyrimidin-4-ol 3680-71-5 N-Methylbenzylamine 32634-66-5

Suppliers and manufacturers

Hangzhou ICH Biofarm Co., Ltd

N-methyl-N-((3R,4R)-4-methylpiperidin-3-yl)-7H-pyrrolo[2,3-d]pyrimidin-4-amine CAS:477600-74-1

Cangzhou Kangrui Pharma Tech Co. Ltd.,

N-Methyl-N-((3R,4R)-4-methylpiperidin-3-yl)-7H-pyrrolo[2,3-d]pyrimidin-4-amine CAS:477600-74-1

career henan chemical co

$40.00
N-methyl-N-((3R,4R)-4-methylpiperidin-3-yl)-7H-pyrrolo[2,3-d]pyrimidin-4-amine CAS:477600-74-1

TAIZHOU YUXIN BIOTECHNOLOGY CO,.LTD

Capot Chemical Co.,Ltd.

Beijing Cooperate Pharmaceutical Co.,Ltd

Henan Tianfu Chemical Co.,Ltd.

TianYuan Pharmaceutical CO.,LTD

Standardpharm Co. Ltd.

Alchem Pharmtech,Inc.

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N-methyl-N-((3R,4R)-4-methylpiperidin-3-yl)-7H-pyrrolo[2,3-d]pyrimidin-4-amine

Properties

Safety Information

Description

Related product price

Suppliers and manufacturers