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ChemicalBook >> CAS DataBase List >> N-[3-[[5-Iodo-4-[[3-[(2-thienylcarbonyl)amino]propyl]amino]-2-pyrimidinyl]amino]phenyl]-1-pyrrolidinecarboxamide

N-[3-[[5-Iodo-4-[[3-[(2-thienylcarbonyl)amino]propyl]amino]-2-pyrimidinyl]amino]phenyl]-1-pyrrolidinecarboxamide

$16 - $5180
Product name: N-[3-[[5-Iodo-4-[[3-[(2-thienylcarbonyl)amino]propyl]amino]-2-pyrimidinyl]amino]phenyl]-1-pyrrolidinecarboxamide
CAS: 702675-74-9
MF: C23H26IN7O2S
MW: 591.47
EINECS:200-256-5
MDL Number:MFCD12546134
Synonyms:N-[3-[[5-Iodo-4-[[3-[(2-thienylcarbonyl)amino]propyl]amino]-2-pyrimidinyl]amino]phenyl]-1-pyrrolidinecarboxamide;BX 795;N-[3-[[5-Iodo-4-[[3-[(2-thienylcarbonyl)aMino]propyl]aMino]-2-pyriMidinyl]aMino]phenyl]-1-pyrrolidin;BX795/BX-795;N-(3-(5-IODO-4-(3-(THIOPHENE-2-CARBOXAMIDO)PROPYLAMINO)PYRIMIDIN-2-YLAMINO)PHENYL)PYRROLIDINE-1-CARBOXAMIDE;N-[3-[[5-Iodo-4-[[3-[(2-thienylcarbonyl)amino]propyl]amino]-2-pyrimidinyl]amino]phenyl]-1-pyrrolidinecarboxamide BX-795;BX-795 hydrochloride;N-[3-[[5-iodo-4-[[3-[(2-thienylcarbonyl)amino]propyl]amino]-2-pyrimidinyl]amino]phenyl]-1-Pyrrolidinecarboxamide hydrochloride

Price75 Properties Safety Information Description

75 prices

Selected condition：

Brand

aablocks
ACHEMBLOCK
Adipogen Life Sciences
AK Scientific
Ambeed
American Custom Chemicals Corporation
ApexBio Technology
Arctom
AvaChem
Axon Medchem
Biorbyt Ltd
Cayman Chemical
ChemScene
DC Chemicals
Matrix Scientific
Sigma-Aldrich
Tocris
TRC
Usbiological

Package

EvaluationSample
10mM*1mLinDMSO(Solid+Solvent)
10mM(in1mLDMSO)
1unit
10
50
10mM*1mLinDMSO(Solution)
10mM*1mLinDMSO
10mM(in 1mL DMSO)
1mg
2mg
5mg
10.00mg
10mg
25mg
50mg
100.00mg
100mg
200mg
250mg
1G
1000mg

Manufactureraablocks
Product numberAA005KCI
Product descriptionBX795 98%
Packaging1mg
Price$16
Updated2026-05-28
Buy

Manufactureraablocks
Product numberAA005KCI
Product descriptionBX795 98%
Packaging5mg
Price$33
Updated2026-05-28
Buy

Manufactureraablocks
Product numberAA005KCI
Product descriptionBX795 98%
Packaging10mg
Price$45
Updated2026-05-28
Buy

Manufactureraablocks
Product numberAA005KCI
Product descriptionBX795 98%
Packaging25mg
Price$70
Updated2026-05-28
Buy

Manufactureraablocks
Product numberAA005KCI
Product descriptionBX795 98%
Packaging50mg
Price$113
Updated2026-05-28
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Manufactureraablocks
Product numberAA005KCI
Product descriptionBX795 98%
Packaging100mg
Price$176
Updated2026-05-28
Buy

Manufactureraablocks
Product numberAA005KCI
Product descriptionBX795 98%
Packaging250mg
Price$303
Updated2026-05-28
Buy

ManufacturerACHEMBLOCK
Product numberR16017
Product descriptionBX795 98%
Packaging1G
Price$1045
Updated2026-05-27
Buy

ManufacturerACHEMBLOCK
Product numberR16017
Product descriptionBX795 98%
Packaging100MG
Price$175
Updated2026-05-27
Buy

ManufacturerAdipogen Life Sciences
Product numberSYN-1026-M010
Product descriptionBX-795 ≥95%
Packaging10mg
Price$146
Updated2026-05-06
Buy

ManufacturerAdipogen Life Sciences
Product numberSYN-1026-M001
Product descriptionBX-795 ≥95%
Packaging1mg
Price$70
Updated2026-05-06
Buy

ManufacturerAdipogen Life Sciences
Product numberSYN-1026-M005
Product descriptionBX-795 ≥95%
Packaging5mg
Price$108
Updated2026-05-06
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ManufacturerAdipogen Life Sciences
Product numberSYN-1026-M050
Product descriptionBX-795 ≥95%
Packaging50mg
Price$583
Updated2026-05-06
Buy

ManufacturerAK Scientific
Product number2292AH
Product descriptionN-(3-(4-(2-(2-Formamidothiophen-3-yl)propanamido)-5-iodopyrimidin-2-ylamino)phenyl)pyrrolidine-1-carboxamide
Packaging100mg
Price$712
Updated2021-12-16
Buy

ManufacturerAK Scientific
Product number2292AH
Product descriptionN-(3-(4-(2-(2-Formamidothiophen-3-yl)propanamido)-5-iodopyrimidin-2-ylamino)phenyl)pyrrolidine-1-carboxamide
Packaging10mg
Price$190
Updated2021-12-16
Buy

ManufacturerAmbeed
Product numberA700044
Product descriptionBX795 98%
Packaging100mg
Price$222
Updated2026-06-05
Buy

Manufacturer	Product number	Product description	Packaging	Price	Updated	Buy
aablocks	AA005KCI	BX795 98%	1mg	$16	2026-05-28	Buy
aablocks	AA005KCI	BX795 98%	5mg	$33	2026-05-28	Buy
aablocks	AA005KCI	BX795 98%	10mg	$45	2026-05-28	Buy
aablocks	AA005KCI	BX795 98%	25mg	$70	2026-05-28	Buy
aablocks	AA005KCI	BX795 98%	50mg	$113	2026-05-28	Buy
aablocks	AA005KCI	BX795 98%	100mg	$176	2026-05-28	Buy
aablocks	AA005KCI	BX795 98%	250mg	$303	2026-05-28	Buy
ACHEMBLOCK	R16017	BX795 98%	1G	$1045	2026-05-27	Buy
ACHEMBLOCK	R16017	BX795 98%	100MG	$175	2026-05-27	Buy
Adipogen Life Sciences	SYN-1026-M010	BX-795 ≥95%	10mg	$146	2026-05-06	Buy
Adipogen Life Sciences	SYN-1026-M001	BX-795 ≥95%	1mg	$70	2026-05-06	Buy
Adipogen Life Sciences	SYN-1026-M005	BX-795 ≥95%	5mg	$108	2026-05-06	Buy
Adipogen Life Sciences	SYN-1026-M050	BX-795 ≥95%	50mg	$583	2026-05-06	Buy
AK Scientific	2292AH	N-(3-(4-(2-(2-Formamidothiophen-3-yl)propanamido)-5-iodopyrimidin-2-ylamino)phenyl)pyrrolidine-1-carboxamide	100mg	$712	2021-12-16	Buy
AK Scientific	2292AH	N-(3-(4-(2-(2-Formamidothiophen-3-yl)propanamido)-5-iodopyrimidin-2-ylamino)phenyl)pyrrolidine-1-carboxamide	10mg	$190	2021-12-16	Buy
Ambeed	A700044	BX795 98%	100mg	$222	2026-06-05	Buy

Next Last

Properties

Melting point :>163°C (dec.)
Density :1.644
storage temp. :2-8°C
solubility :DMSO: soluble15mg/mL, clear
form :powder
pka :12.57±0.70(Predicted)
color :white to light brown
Stability :Stable for 2 years from date of purchase as supplied. Solutions in DMSO may be stored at -20°C for up to 3 months.
InChIKey :VAVXGGRQQJZYBL-UHFFFAOYSA-N
SMILES :Cl.Ic1cnc(Nc2cccc(NC(=O)N3CCCC3)c2)nc1NCCCNC(=O)c4cccs4

Safety Information

Symbol(GHS):

Signal word:

warning

Hazard statements:

Code	Hazard statements	Hazard class	Category	Signal word	P-Codes
H315	Causes skin irritation	Skin corrosion/irritation	Category 2	Warning	P264, P280, P302+P352, P321,P332+P313, P362
H319	Causes serious eye irritation	Serious eye damage/eye irritation	Category 2A	Warning	P264, P280, P305+P351+P338,P337+P313P
H335	May cause respiratory irritation	Specific target organ toxicity, single exposure;Respiratory tract irritation	Category 3	Warning

Precautionary statements:

P261	Avoid breathing dust/fume/gas/mist/vapours/spray.
P264	Wash hands thoroughly after handling.
P264	Wash skin thouroughly after handling.
P271	Use only outdoors or in a well-ventilated area.
P280	Wear protective gloves/protective clothing/eye protection/face protection.
P302+P352	IF ON SKIN: wash with plenty of soap and water.
P304+P340	IF INHALED: Remove victim to fresh air and Keep at rest in a position comfortable for breathing.
P305+P351+P338	IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continuerinsing.
P312	Call a POISON CENTER or doctor/physician if you feel unwell.
P321	Specific treatment (see … on this label).
P332+P313	IF SKIN irritation occurs: Get medical advice/attention.
P337+P313	IF eye irritation persists: Get medical advice/attention.
P362	Take off contaminated clothing and wash before reuse.
P403+P233	Store in a well-ventilated place. Keep container tightly closed.
P405	Store locked up.
P501	Dispose of contents/container to..…

Description

3-Phosphoinositide-dependent protein kinase 1 (PDK1) is a serine-threonine kinase that phosphorylates and activates a range of other kinases, including PKB, PKA, and certain isoforms of PKC. BX-795 is a potent, ATP-competitive inhibitor of PDK1 in vitro (IC50 = 11 nM) and in cells (IC50 = 300 nM). At comparable concentrations, BX-795 also inhibits ERK8, MAPK-interacting kinase 2, Aurora B, Aurora C, MAP/microtubule affinity-regulating kinases 1-4, TNF receptor associated factor-associated NF-κB activator-binding kinase 1, IκB kinase ε, and additional kinases.

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Suppliers and manufacturers

Shanghai Boyle Chemical Co., Ltd. J & K SCIENTIFIC LTD. Chembest Research Laboratories Limited Jinan Trio PharmaTech Co., Ltd. Dalian Meilun Biotech Co., Ltd. Wuhan TCASChem Technology Co., Ltd. Shanghai Topbiochem Technology Co., Ltd Haoyuan Chemexpress Co., Ltd. SYN|thesis med chem P/L Shanghai Aladdin Bio-Chem Technology Co.,LTD

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N-[3-[[5-Iodo-4-[[3-[(2-thienylcarbonyl)amino]propyl]amino]-2-pyrimidinyl]amino]phenyl]-1-pyrrolidinecarboxamide

Properties

Safety Information

Description

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