(1,3-Benzothiazol-2-yl)[2-[[4-[(morpholin-4-yl)methyl]benzyl]oxy]pyrimidin-4-yl]acetonitrile
![(1,3-Benzothiazol-2-yl)[2-[[4-[(morpholin-4-yl)methyl]benzyl]oxy]pyrimidin-4-yl]acetonitrile price.](/CAS/GIF/848344-36-5.gif)
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- $40 - $4300
- Product name: (1,3-Benzothiazol-2-yl)[2-[[4-[(morpholin-4-yl)methyl]benzyl]oxy]pyrimidin-4-yl]acetonitrile
- CAS: 848344-36-5
- MF: C25H23N5O2S
- MW: 457.55
- EINECS:604-604-1
- MDL Number:MFCD08272350
- Synonyms:(1,3-Benzothiazol-2-yl)[2-[[4-[(morpholin-4-yl)methyl]benzyl]oxy]pyrimidin-4-yl]acetonitrile;AS 602801;Bentamapimod;AS 602801 (BentaMapiMod);(1,3-Benzothiazol-2-yl)[2-[[4-[(morpholin-4-yl)methyl]benzyl]oxy]pyrimidin-4-yl]acetonitrile AS602801(Bentamapimod);Bentamapimod (AS 602801);CS-401;2-(1,3-benzothiazol-2-yl)-2-[2-[[4-(morpholin-4-ylmethyl)phenyl]methoxy]pyrimidin-4-yl]acetonitrile
34 prices
Selected condition：
Brand
- Adipogen Life Sciences
- AK Scientific
- ApexBio Technology
- Axon Medchem
- Biosynth Carbosynth
- Cayman Chemical
- ChemScene
- Crysdot
- CSNpharm
- DC Chemicals
- Sigma-Aldrich
- TRC
Package
- 1mg
- 2mg
- 5mg
- 10mg
- 25mg
- 2x25mg
- 50mg
- 100mg
- 200mg
- 10mM(in 1mL DMSO)
- 500mg
- 1g
- 2g
- ManufacturerAdipogen Life Sciences
- Product numberSYN-1147-M001
- Product descriptionBentamapimod ≥95%
- Packaging1mg
- Price$205
- Updated2021-12-16
- Buy
- ManufacturerAK Scientific
- Product numberSYN1147
- Product descriptionBentamapimod
- Packaging10mg
- Price$480
- Updated2021-12-16
- Buy
- ManufacturerApexBio Technology
- Product numberA3189
- Product descriptionAS602801
- Packaging10mM(in 1mL DMSO)
- Price$77
- Updated2021-12-16
- Buy
- ManufacturerApexBio Technology
- Product numberA3189
- Product descriptionAS602801
- Packaging10mg
- Price$120
- Updated2021-12-16
- Buy
- ManufacturerApexBio Technology
- Product numberA3189
- Product descriptionAS602801
- Packaging50mg
- Price$250
- Updated2021-12-16
- Buy
- ManufacturerApexBio Technology
- Product numberA3189
- Product descriptionAS602801
- Packaging200mg
- Price$800
- Updated2021-12-16
- Buy
- ManufacturerApexBio Technology
- Product numberA3189
- Product descriptionAS602801
- Packaging500mg
- Price$1500
- Updated2021-12-16
- Buy
- ManufacturerAxon Medchem
- Product numberAxon2002
- Product descriptionAS602801-Bentamapimod 98%
- Packaging25mg
- Price$231
- Updated2021-12-16
- Buy
- ManufacturerAxon Medchem
- Product numberAxon2002
- Product descriptionAS602801-Bentamapimod 98%
- Packaging2x25mg
- Price$330
- Updated2021-12-16
- Buy
- ManufacturerBiosynth Carbosynth
- Product numberFB146407
- Product descriptionBentamapimod
- Packaging1mg
- Price$80
- Updated2021-12-16
- Buy
- ManufacturerBiosynth Carbosynth
- Product numberFB146407
- Product descriptionBentamapimod
- Packaging2mg
- Price$140
- Updated2021-12-16
- Buy
- ManufacturerBiosynth Carbosynth
- Product numberFB146407
- Product descriptionBentamapimod
- Packaging5mg
- Price$300
- Updated2021-12-16
- Buy
- ManufacturerBiosynth Carbosynth
- Product numberFB146407
- Product descriptionBentamapimod
- Packaging10mg
- Price$500
- Updated2021-12-16
- Buy
- ManufacturerBiosynth Carbosynth
- Product numberFB146407
- Product descriptionBentamapimod
- Packaging25mg
- Price$1000
- Updated2021-12-16
- Buy
- ManufacturerCayman Chemical
- Product number21482
- Product descriptionBentamapimod ≥98%
- Packaging1mg
- Price$40
- Updated2024-03-01
- Buy
- ManufacturerCayman Chemical
- Product number21482
- Product descriptionBentamapimod ≥98%
- Packaging5mg
- Price$177
- Updated2024-03-01
- Buy
| Manufacturer | Product number | Product description | Packaging | Price | Updated | Buy |
|---|---|---|---|---|---|---|
| Adipogen Life Sciences | SYN-1147-M001 | Bentamapimod ≥95% | 1mg | $205 | 2021-12-16 | Buy |
| AK Scientific | SYN1147 | Bentamapimod | 10mg | $480 | 2021-12-16 | Buy |
| ApexBio Technology | A3189 | AS602801 | 10mM(in 1mL DMSO) | $77 | 2021-12-16 | Buy |
| ApexBio Technology | A3189 | AS602801 | 10mg | $120 | 2021-12-16 | Buy |
| ApexBio Technology | A3189 | AS602801 | 50mg | $250 | 2021-12-16 | Buy |
| ApexBio Technology | A3189 | AS602801 | 200mg | $800 | 2021-12-16 | Buy |
| ApexBio Technology | A3189 | AS602801 | 500mg | $1500 | 2021-12-16 | Buy |
| Axon Medchem | Axon2002 | AS602801-Bentamapimod 98% | 25mg | $231 | 2021-12-16 | Buy |
| Axon Medchem | Axon2002 | AS602801-Bentamapimod 98% | 2x25mg | $330 | 2021-12-16 | Buy |
| Biosynth Carbosynth | FB146407 | Bentamapimod | 1mg | $80 | 2021-12-16 | Buy |
| Biosynth Carbosynth | FB146407 | Bentamapimod | 2mg | $140 | 2021-12-16 | Buy |
| Biosynth Carbosynth | FB146407 | Bentamapimod | 5mg | $300 | 2021-12-16 | Buy |
| Biosynth Carbosynth | FB146407 | Bentamapimod | 10mg | $500 | 2021-12-16 | Buy |
| Biosynth Carbosynth | FB146407 | Bentamapimod | 25mg | $1000 | 2021-12-16 | Buy |
| Cayman Chemical | 21482 | Bentamapimod ≥98% | 1mg | $40 | 2024-03-01 | Buy |
| Cayman Chemical | 21482 | Bentamapimod ≥98% | 5mg | $177 | 2024-03-01 | Buy |
Properties
Boiling point :666.5±65.0 °C(Predicted)
Density :1.326
storage temp. :2-8°C
solubility :insoluble in H2O; insoluble in EtOH; ≥11.45 mg/mL in DMSO
form :solid
pka :6.47±0.10(Predicted)
color :Light yellow to yellow
InChI :1S/C25H23N5O2S/c26-15-20(24-28-22-3-1-2-4-23(22)33-24)21-9-10-27-25(29-21)32-17-19-7-5-18(6-8-19)16-30-11-13-31-14-12-30/h1-10,20H,11-14,16-17H2
InChIKey :XCPPIJCBCWUBNT-UHFFFAOYSA-N
SMILES :[s]1c2c(nc1C(c3nc(ncc3)OCc4ccc(cc4)CN5CCOCC5)C#N)cccc2
Density :1.326
storage temp. :2-8°C
solubility :insoluble in H2O; insoluble in EtOH; ≥11.45 mg/mL in DMSO
form :solid
pka :6.47±0.10(Predicted)
color :Light yellow to yellow
InChI :1S/C25H23N5O2S/c26-15-20(24-28-22-3-1-2-4-23(22)33-24)21-9-10-27-25(29-21)32-17-19-7-5-18(6-8-19)16-30-11-13-31-14-12-30/h1-10,20H,11-14,16-17H2
InChIKey :XCPPIJCBCWUBNT-UHFFFAOYSA-N
SMILES :[s]1c2c(nc1C(c3nc(ncc3)OCc4ccc(cc4)CN5CCOCC5)C#N)cccc2
Safety Information
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| Signal word: | Warning | ||||||||||||||||||||||||||||
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Description
Bentamapimod is an orally bioavailable inhibitor of Jun kinases (JNKs), with IC50 values for JNK1, JNK2, and JNK3 of 80, 90, and 230 nM, respectively. It is selective for JNKs over a panel of 25 related kinases. Bentamapimod induces regression of endometriotic lesions without suppressing estrogen action in animal models of endometriosis. It blocks proliferation and induces apoptosis of T cells in vitro and inhibits cancer stem cell survival, self-renewal, and tumor-initiating capacity in vitro and in mice.More related product prices
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