(S)-2-[(Bis(3,5-bis(trifluoromethyl)phenyl)trimethylsilanyloxy)methyl]pyrrolidine, (S)-2-[(Bis(3,5-bis(trifluoromethyl)phenyl)trimethylsilyloxy)methyl]pyrrolidine, (S)-α,α-[3,5-Bis(trifluoromethyl)phenyl]prolinol trimethylsilyl ether
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- $55 - $4980
- Product name: (S)-2-[(Bis(3,5-bis(trifluoromethyl)phenyl)trimethylsilanyloxy)methyl]pyrrolidine, (S)-2-[(Bis(3,5-bis(trifluoromethyl)phenyl)trimethylsilyloxy)methyl]pyrrolidine, (S)-α,α-[3,5-Bis(trifluoromethyl)phenyl]prolinol trimethylsilyl ether
- CAS: 848821-61-4
- MF: C24H23F12NOSi
- MW: 597.51
- EINECS:
- MDL Number:MFCD09750447
- Synonyms:(S)-α,α-Bis[3,5-bis(trifluoromethyl)phenyl]-2-pyrrolidinemethanol trimethylsilyl ether;Pyrrolidine, 2-[bis[3,5-bis(trifluoromethyl)phenyl][(trimethylsilyl)oxy]methyl]-, (2S)-;(S)-α,α-BIS(3,5-BIS(TRIFLUOROMET;(S)-α,α-Bis[3,5-bis(trifluoroMethyl)phenyl]-2-pyrrolidineMethanol triMethylsilyl ether 97%;(S)-2-[(Bis(3,5-bis(trifluoroMethyl)phenyl)triMethylsilanyloxy)Methyl]pyrrolidine;(S)-α,α-[3,5-Bis(trifluoroMethyl)phenyl]prolinol triMethylsilyl ether;(S)-alpha,alpha-Bis[3,5-bis(trifluoroMethyl)phenyl]-2-pyrrolidineMethanol triMethylsilyl ether 97%;S-2-[bis[3,5-bis(trifluoroMethyl)phenyl][(triMethyl silyl)oxy]Methyl]-Pyrrolidine
31 prices
Selected condition:
Brand
- aablocks
- ACHEMBLOCK
- Alichem
- American Custom Chemicals Corporation
- Biosynth
- Chemenu
- Crysdot
- JR MediChem
- Matrix Scientific
- Sigma-Aldrich
- TCI Chemical
- TRC
Package
- 100mg
- 250mg
- 500mg
- 1g
- 2g
- 2.5g
- 5g
- 25G
- Manufactureraablocks
- Product numberAA004QD5
- Product description(S)-2-(Bis(3,5-bis(trifluoromethyl)phenyl)((trimethylsilyl)oxy)methyl)pyrrolidine ≥97%
- Packaging100mg
- Price$69
- Updated2026-05-28
- Buy
- Manufactureraablocks
- Product numberAA004QD5
- Product description(S)-2-(Bis(3,5-bis(trifluoromethyl)phenyl)((trimethylsilyl)oxy)methyl)pyrrolidine ≥97%
- Packaging250mg
- Price$142
- Updated2026-05-28
- Buy
- Manufactureraablocks
- Product numberAA004QD5
- Product description(S)-2-(Bis(3,5-bis(trifluoromethyl)phenyl)((trimethylsilyl)oxy)methyl)pyrrolidine ≥97%
- Packaging1g
- Price$360
- Updated2026-05-28
- Buy
- Manufactureraablocks
- Product numberAA004QD5
- Product description(S)-2-(Bis(3,5-bis(trifluoromethyl)phenyl)((trimethylsilyl)oxy)methyl)pyrrolidine ≥97%
- Packaging5g
- Price$952
- Updated2026-05-28
- Buy
- ManufacturerACHEMBLOCK
- Product numberY220373
- Product description(S)-2-(bis(3,5-bis(trifluoromethyl)phenyl)((trimethylsilyl)oxy)methyl)pyrrolidine 97.00%
- Packaging5G
- Price$830
- Updated2026-05-27
- Buy
- ManufacturerACHEMBLOCK
- Product numberY220373
- Product description(S)-2-(bis(3,5-bis(trifluoromethyl)phenyl)((trimethylsilyl)oxy)methyl)pyrrolidine 97.00%
- Packaging25G
- Price$2160
- Updated2026-05-27
- Buy
- ManufacturerACHEMBLOCK
- Product numberY220373
- Product description(S)-2-(bis(3,5-bis(trifluoromethyl)phenyl)((trimethylsilyl)oxy)methyl)pyrrolidine 97.00%
- Packaging1G
- Price$235
- Updated2026-05-27
- Buy
- ManufacturerAlichem
- Product number848821614
- Product description(S)-2-(Bis(3,5-bis(trifluoromethyl)phenyl)((trimethylsilyl)oxy)methyl)pyrrolidine
- Packaging5g
- Price$610
- Updated2021-12-16
- Buy
- ManufacturerAmerican Custom Chemicals Corporation
- Product numberORS0001315
- Product description(S)-ALPHA,ALPHA-BIS[3,5-BIS(TRIFLUOROMETHYL)PHENYL]-2-PYRROLIDINEMETHANOL TRIMETHYLSILYL ETHER 97.00%
- Packaging1G
- Price$735.54
- Updated2021-12-16
- Buy
- ManufacturerAmerican Custom Chemicals Corporation
- Product numberORS0001315
- Product description(S)-ALPHA,ALPHA-BIS[3,5-BIS(TRIFLUOROMETHYL)PHENYL]-2-PYRROLIDINEMETHANOL TRIMETHYLSILYL ETHER 97.00%
- Packaging5G
- Price$1130.28
- Updated2021-12-16
- Buy
- ManufacturerBiosynth
- Product numberFB100522
- Product description(S)-2-[Bis[3,5-bis(trifluoromethyl)phenyl](trimethylsilyloxy)methyl]pyrrolidine
- Packaging2g
- Price$350
- Updated2021-12-16
- Buy
- ManufacturerBiosynth
- Product numberFB100522
- Product description(S)-2-[Bis[3,5-bis(trifluoromethyl)phenyl](trimethylsilyloxy)methyl]pyrrolidine
- Packaging1g
- Price$220
- Updated2021-12-16
- Buy
- ManufacturerBiosynth
- Product numberFB100522
- Product description(S)-2-[Bis[3,5-bis(trifluoromethyl)phenyl](trimethylsilyloxy)methyl]pyrrolidine
- Packaging100mg
- Price$55
- Updated2021-12-16
- Buy
- ManufacturerBiosynth
- Product numberFB100522
- Product description(S)-2-[Bis[3,5-bis(trifluoromethyl)phenyl](trimethylsilyloxy)methyl]pyrrolidine
- Packaging500mg
- Price$140
- Updated2021-12-16
- Buy
- ManufacturerBiosynth
- Product numberFB100522
- Product description(S)-2-[Bis[3,5-bis(trifluoromethyl)phenyl](trimethylsilyloxy)methyl]pyrrolidine
- Packaging250mg
- Price$90
- Updated2021-12-16
- Buy
- ManufacturerChemenu
- Product numberCM132747
- Product description(S)-2-(bis(3,5-bis(trifluoromethyl)phenyl)((trimethylsilyl)oxy)methyl)pyrrolidine 95%
- Packaging5g
- Price$524
- Updated2021-12-16
- Buy
| Manufacturer | Product number | Product description | Packaging | Price | Updated | Buy |
|---|---|---|---|---|---|---|
| aablocks | AA004QD5 | (S)-2-(Bis(3,5-bis(trifluoromethyl)phenyl)((trimethylsilyl)oxy)methyl)pyrrolidine ≥97% | 100mg | $69 | 2026-05-28 | Buy |
| aablocks | AA004QD5 | (S)-2-(Bis(3,5-bis(trifluoromethyl)phenyl)((trimethylsilyl)oxy)methyl)pyrrolidine ≥97% | 250mg | $142 | 2026-05-28 | Buy |
| aablocks | AA004QD5 | (S)-2-(Bis(3,5-bis(trifluoromethyl)phenyl)((trimethylsilyl)oxy)methyl)pyrrolidine ≥97% | 1g | $360 | 2026-05-28 | Buy |
| aablocks | AA004QD5 | (S)-2-(Bis(3,5-bis(trifluoromethyl)phenyl)((trimethylsilyl)oxy)methyl)pyrrolidine ≥97% | 5g | $952 | 2026-05-28 | Buy |
| ACHEMBLOCK | Y220373 | (S)-2-(bis(3,5-bis(trifluoromethyl)phenyl)((trimethylsilyl)oxy)methyl)pyrrolidine 97.00% | 5G | $830 | 2026-05-27 | Buy |
| ACHEMBLOCK | Y220373 | (S)-2-(bis(3,5-bis(trifluoromethyl)phenyl)((trimethylsilyl)oxy)methyl)pyrrolidine 97.00% | 25G | $2160 | 2026-05-27 | Buy |
| ACHEMBLOCK | Y220373 | (S)-2-(bis(3,5-bis(trifluoromethyl)phenyl)((trimethylsilyl)oxy)methyl)pyrrolidine 97.00% | 1G | $235 | 2026-05-27 | Buy |
| Alichem | 848821614 | (S)-2-(Bis(3,5-bis(trifluoromethyl)phenyl)((trimethylsilyl)oxy)methyl)pyrrolidine | 5g | $610 | 2021-12-16 | Buy |
| American Custom Chemicals Corporation | ORS0001315 | (S)-ALPHA,ALPHA-BIS[3,5-BIS(TRIFLUOROMETHYL)PHENYL]-2-PYRROLIDINEMETHANOL TRIMETHYLSILYL ETHER 97.00% | 1G | $735.54 | 2021-12-16 | Buy |
| American Custom Chemicals Corporation | ORS0001315 | (S)-ALPHA,ALPHA-BIS[3,5-BIS(TRIFLUOROMETHYL)PHENYL]-2-PYRROLIDINEMETHANOL TRIMETHYLSILYL ETHER 97.00% | 5G | $1130.28 | 2021-12-16 | Buy |
| Biosynth | FB100522 | (S)-2-[Bis[3,5-bis(trifluoromethyl)phenyl](trimethylsilyloxy)methyl]pyrrolidine | 2g | $350 | 2021-12-16 | Buy |
| Biosynth | FB100522 | (S)-2-[Bis[3,5-bis(trifluoromethyl)phenyl](trimethylsilyloxy)methyl]pyrrolidine | 1g | $220 | 2021-12-16 | Buy |
| Biosynth | FB100522 | (S)-2-[Bis[3,5-bis(trifluoromethyl)phenyl](trimethylsilyloxy)methyl]pyrrolidine | 100mg | $55 | 2021-12-16 | Buy |
| Biosynth | FB100522 | (S)-2-[Bis[3,5-bis(trifluoromethyl)phenyl](trimethylsilyloxy)methyl]pyrrolidine | 500mg | $140 | 2021-12-16 | Buy |
| Biosynth | FB100522 | (S)-2-[Bis[3,5-bis(trifluoromethyl)phenyl](trimethylsilyloxy)methyl]pyrrolidine | 250mg | $90 | 2021-12-16 | Buy |
| Chemenu | CM132747 | (S)-2-(bis(3,5-bis(trifluoromethyl)phenyl)((trimethylsilyl)oxy)methyl)pyrrolidine 95% | 5g | $524 | 2021-12-16 | Buy |
Properties
Melting point :48-56 °C
Boiling point :382.4±37.0 °C(Predicted)
Density :1.319±0.06 g/cm3(Predicted)
Flash point :110 °C
storage temp. :under inert gas (nitrogen or Argon) at 2-8°C
solubility :Chloroform (Slightly), Ethyl Acetate (Slightly)
form :Solid
pka :9.34±0.10(Predicted)
color :White to Off-White
InChIKey :MOHRGTBNEJKFMB-IBGZPJMESA-N
SMILES :C[Si](C)(C)OC([C@@H]1CCCN1)(c2cc(cc(c2)C(F)(F)F)C(F)(F)F)c3cc(cc(c3)C(F)(F)F)C(F)(F)F
Boiling point :382.4±37.0 °C(Predicted)
Density :1.319±0.06 g/cm3(Predicted)
Flash point :110 °C
storage temp. :under inert gas (nitrogen or Argon) at 2-8°C
solubility :Chloroform (Slightly), Ethyl Acetate (Slightly)
form :Solid
pka :9.34±0.10(Predicted)
color :White to Off-White
InChIKey :MOHRGTBNEJKFMB-IBGZPJMESA-N
SMILES :C[Si](C)(C)OC([C@@H]1CCCN1)(c2cc(cc(c2)C(F)(F)F)C(F)(F)F)c3cc(cc(c3)C(F)(F)F)C(F)(F)F
Safety Information
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| Signal word: | Warning | ||||||||||||||||||||||||||||
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Description
(S)-α,α-Bis[3,5-di(trifluoromethyl)phenyl]-O-(trimethylsilyl)pyrrolidine-2-methanol, is a diarylprolinol silyl ether organocatalyst. It is able to catalyze a variety of bond-forming reactions such as C-C, C-N, C-O, C-S, and C-Hal in high yields and excellent levels of enantiocontrol.Related product price
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