2,4-PyriMidinediaMine, 5-[5-iodo-4-Methoxy-2-(1-Methylethyl)phenoxy]-
![2,4-PyriMidinediaMine, 5-[5-iodo-4-Methoxy-2-(1-Methylethyl)phenoxy]- price.](/CAS/GIF/865305-30-2.gif)
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- $12 - $1950
- Product name: 2,4-PyriMidinediaMine, 5-[5-iodo-4-Methoxy-2-(1-Methylethyl)phenoxy]-
- CAS: 865305-30-2
- MF: C14H17IN4O2
- MW: 400.21
- EINECS:
- MDL Number:MFCD18782750
- Synonyms:2,4-PyriMidinediaMine, 5-[5-iodo-4-Methoxy-2-(1-Methylethyl)phenoxy]-;AF 353;Ro 4;5-{[5-iodo-2-(1-Methylethyl)-4-(Methyloxy)phenyl]oxy}-2,4-pyriMidinediaMine;CHEMBL526307;CHEMBL526307;AF 353;AF353;CS-2469;5-[5-iodo-4-methoxy-2-(1-methylethyl)phenoxy]-2,4-pyrimidinediamine hydrochloride Ro 4 hydrochloride
30 prices
Selected condition：
Brand
- aablocks
- ACHEMBLOCK
- AK Scientific
- Biosynth
- Cayman Chemical
- ChemScene
- Crysdot
- DC Chemicals
Package
- 2mg
- 10mM*1mLinDMSO
- 1mg
- 5mg
- 10mg
- 25mg
- 50mg
- 100mg
- 250MG
- 1G
- Manufactureraablocks
- Product numberAA00369N
- Product description5-(5-Iodo-2-isopropyl-4-methoxyphenoxy)pyrimidine-2,4-diamine 98+%
- Packaging1mg
- Price$12
- Updated2026-05-28
- Buy
- Manufactureraablocks
- Product numberAA00369N
- Product description5-(5-Iodo-2-isopropyl-4-methoxyphenoxy)pyrimidine-2,4-diamine ≥98%
- Packaging5mg
- Price$29
- Updated2026-05-28
- Buy
- Manufactureraablocks
- Product numberAA00369N
- Product description5-(5-Iodo-2-isopropyl-4-methoxyphenoxy)pyrimidine-2,4-diamine 98+%
- Packaging25mg
- Price$85
- Updated2026-05-28
- Buy
- Manufactureraablocks
- Product numberAA00369N
- Product description5-(5-Iodo-2-isopropyl-4-methoxyphenoxy)pyrimidine-2,4-diamine 98+%
- Packaging50mg
- Price$142
- Updated2026-05-28
- Buy
- Manufactureraablocks
- Product numberAA00369N
- Product description5-(5-Iodo-2-isopropyl-4-methoxyphenoxy)pyrimidine-2,4-diamine 98+%
- Packaging100mg
- Price$241
- Updated2026-05-28
- Buy
- ManufacturerACHEMBLOCK
- Product numberQ70019
- Product description5-(5-iodo-2-isopropyl-4-methoxyphenoxy)pyrimidine-2,4-diamine 98%
- Packaging100MG
- Price$435
- Updated2026-05-27
- Buy
- ManufacturerACHEMBLOCK
- Product numberQ70019
- Product description5-(5-iodo-2-isopropyl-4-methoxyphenoxy)pyrimidine-2,4-diamine 98%
- Packaging250MG
- Price$650
- Updated2026-05-27
- Buy
- ManufacturerACHEMBLOCK
- Product numberQ70019
- Product description5-(5-iodo-2-isopropyl-4-methoxyphenoxy)pyrimidine-2,4-diamine 98%
- Packaging1G
- Price$1950
- Updated2026-05-27
- Buy
- ManufacturerAK Scientific
- Product number1897CW
- Product description2,4-Pyrimidinediamine,5-[5-iodo-4-methoxy-2-(1-methylethyl)phenoxy]-
- Packaging10mg
- Price$245
- Updated2021-12-16
- Buy
- ManufacturerBiosynth
- Product numberBA165790
- Product descriptionAF 353
- Packaging1mg
- Price$250
- Updated2026-06-04
- Buy
- ManufacturerBiosynth
- Product numberBA165790
- Product descriptionAF 353
- Packaging2mg
- Price$250
- Updated2026-06-04
- Buy
- ManufacturerBiosynth
- Product numberBA165790
- Product descriptionAF 353
- Packaging5mg
- Price$261.25
- Updated2026-06-04
- Buy
- ManufacturerBiosynth
- Product numberBA165790
- Product descriptionAF 353
- Packaging50mg
- Price$507.5
- Updated2021-12-16
- Buy
- ManufacturerBiosynth
- Product numberBA165790
- Product descriptionAF 353
- Packaging25mg
- Price$797.5
- Updated2026-06-04
- Buy
- ManufacturerBiosynth
- Product numberBA165790
- Product descriptionAF 353
- Packaging10mg
- Price$412.5
- Updated2026-06-04
- Buy
- ManufacturerCayman Chemical
- Product number23034
- Product descriptionAF-353
- Packaging10mg
- Price$189
- Updated2022-04-27
- Buy
| Manufacturer | Product number | Product description | Packaging | Price | Updated | Buy |
|---|---|---|---|---|---|---|
| aablocks | AA00369N | 5-(5-Iodo-2-isopropyl-4-methoxyphenoxy)pyrimidine-2,4-diamine 98+% | 1mg | $12 | 2026-05-28 | Buy |
| aablocks | AA00369N | 5-(5-Iodo-2-isopropyl-4-methoxyphenoxy)pyrimidine-2,4-diamine ≥98% | 5mg | $29 | 2026-05-28 | Buy |
| aablocks | AA00369N | 5-(5-Iodo-2-isopropyl-4-methoxyphenoxy)pyrimidine-2,4-diamine 98+% | 25mg | $85 | 2026-05-28 | Buy |
| aablocks | AA00369N | 5-(5-Iodo-2-isopropyl-4-methoxyphenoxy)pyrimidine-2,4-diamine 98+% | 50mg | $142 | 2026-05-28 | Buy |
| aablocks | AA00369N | 5-(5-Iodo-2-isopropyl-4-methoxyphenoxy)pyrimidine-2,4-diamine 98+% | 100mg | $241 | 2026-05-28 | Buy |
| ACHEMBLOCK | Q70019 | 5-(5-iodo-2-isopropyl-4-methoxyphenoxy)pyrimidine-2,4-diamine 98% | 100MG | $435 | 2026-05-27 | Buy |
| ACHEMBLOCK | Q70019 | 5-(5-iodo-2-isopropyl-4-methoxyphenoxy)pyrimidine-2,4-diamine 98% | 250MG | $650 | 2026-05-27 | Buy |
| ACHEMBLOCK | Q70019 | 5-(5-iodo-2-isopropyl-4-methoxyphenoxy)pyrimidine-2,4-diamine 98% | 1G | $1950 | 2026-05-27 | Buy |
| AK Scientific | 1897CW | 2,4-Pyrimidinediamine,5-[5-iodo-4-methoxy-2-(1-methylethyl)phenoxy]- | 10mg | $245 | 2021-12-16 | Buy |
| Biosynth | BA165790 | AF 353 | 1mg | $250 | 2026-06-04 | Buy |
| Biosynth | BA165790 | AF 353 | 2mg | $250 | 2026-06-04 | Buy |
| Biosynth | BA165790 | AF 353 | 5mg | $261.25 | 2026-06-04 | Buy |
| Biosynth | BA165790 | AF 353 | 50mg | $507.5 | 2021-12-16 | Buy |
| Biosynth | BA165790 | AF 353 | 25mg | $797.5 | 2026-06-04 | Buy |
| Biosynth | BA165790 | AF 353 | 10mg | $412.5 | 2026-06-04 | Buy |
| Cayman Chemical | 23034 | AF-353 | 10mg | $189 | 2022-04-27 | Buy |
Properties
Boiling point :510.2±60.0 °C(Predicted)
Density :1.619±0.06 g/cm3(Predicted)
storage temp. :Store at -20°C
solubility :DMSO : ≥ 32 mg/mL (79.96 mM)
pka :6.89±0.10(Predicted)
form :Solid
color :Light brown to brown
InChI :InChI=1S/C14H17IN4O2/c1-7(2)8-4-11(20-3)9(15)5-10(8)21-12-6-18-14(17)19-13(12)16/h4-7H,1-3H3,(H4,16,17,18,19)
InChIKey :AATPYXMXFBBKFO-UHFFFAOYSA-N
SMILES :C1(N)=NC=C(OC2=CC(I)=C(OC)C=C2C(C)C)C(N)=N1
Density :1.619±0.06 g/cm3(Predicted)
storage temp. :Store at -20°C
solubility :DMSO : ≥ 32 mg/mL (79.96 mM)
pka :6.89±0.10(Predicted)
form :Solid
color :Light brown to brown
InChI :InChI=1S/C14H17IN4O2/c1-7(2)8-4-11(20-3)9(15)5-10(8)21-12-6-18-14(17)19-13(12)16/h4-7H,1-3H3,(H4,16,17,18,19)
InChIKey :AATPYXMXFBBKFO-UHFFFAOYSA-N
SMILES :C1(N)=NC=C(OC2=CC(I)=C(OC)C=C2C(C)C)C(N)=N1
Safety Information
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Description
AF-353 is a noncompetitive dual antagonist of the purinoreceptors P2X3 and P2X2/3 (IC50s = 10 and 79.4 nM, respectively). It is selective for P2X3 and P2X2/3 over P2X1, P2X2, P2X4, P2X5, and P2X7 (IC50 = >10 μM for all). It inhibits calcium flux in CHO-K1 cells expressing the rat P2X3 receptor and in 1321N1 cells expressing the human P2X3 and P2X2/3 receptors (IC50s = 8.91, 8.71, and 38.9 nM, respectively). AF-353 decreases the electrical signals in the detrusor, but not striated, muscle of the bladder in female rats.More related product prices
Ro 4 hydrochloride Ro 51 TC-P 262 2,4-PyriMidinediaMine, 5-[5-iodo-4-Methoxy-2-(1-Methylethyl)phenoxy]- 112898-15-4Related product price
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Ro 4 hydrochloride
$37-1268 -
Ro 51
$171.88-1889 -
TC-P 262
$163-1422
Suppliers and manufacturers
BOC Sciences
Zibo Hangyu Biotechnology Development Co., Ltd
HANGZHOU LEAP CHEM CO., LTD.
Aladdin Scientific
NANJING YINGWEN BIOTECHNOLOGY CO LTD
Amadis Chemical Company Limited
Shanghai Jinyin Biological Technology Co., Ltd
Chembest Research Laboratories Limited
Shanghai Lollane Biological Technology Co.,Ltd.
