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ChemicalBook >> CAS DataBase List >> A66

A66

$32 - $4171.86
Product name: A66
CAS: 1166227-08-2
MF: C17H23N5O2S2
MW: 393.53
EINECS:-0
MDL Number:MFCD22378485
Synonyms:(2S)-N1-[2-(tert-Butyl)-4'-methyl[4,5'-bithiazol]-2'-yl]-1,2-pyrrolidinedicarboxamide;CS-435;(2S)-N1-(5-(2-tert-butylthiazol-4-yl)-4-methylthiazol-2-yl)pyrrolidine-1,2-dicarboxamide;(2S)-N1-[2-(tert-Butyl)-4'-methyl[4,5'-bithiazol]-2'-yl]-1,2-pyrrolidinedicarboxamide A 66;A66, 98%, a potent and specific p110α inhibitor;(2S)-N1-[2-(1,1-Dimethylethyl)-4'-methyl[4,5'-bithiazol]-2'-yl]-1,2-pyrrolidinedicarboxamide;A 66;A-66;1,2-Pyrrolidinedicarboxamide, N1-[2-(1,1-dimethylethyl)-4'-methyl[4,5'-bithiazol]-2'-yl]-, (2S)-

Price53 Properties Safety Information Description

53 prices

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Brand

aablocks
ACHEMBLOCK
AK Scientific
Ambeed
American Custom Chemicals Corporation
ApexBio Technology
Arctom
Axon Medchem
Biorbyt Ltd
Biosynth
Cayman Chemical
Chemenu
ChemScene
Crysdot
DC Chemicals
Sigma-Aldrich
Synthonix
TRC

Package

1mg
5mg
10mg
2mg
10mM(in1mLDMSO)
10mM(in 1mL DMSO)
25mg
50mg
100mg
200mg
250mg
1g
5 mg
25 mg

Manufactureraablocks
Product numberAA000CT6
Product descriptionA66 98%
Packaging25mg
Price$102
Updated2026-05-25
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Manufactureraablocks
Product numberAA000CT6
Product descriptionA66 98%
Packaging50mg
Price$172
Updated2026-05-25
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Manufactureraablocks
Product numberAA000CT6
Product descriptionA66
Packaging100mg
Price$327
Updated2026-05-25
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Manufactureraablocks
Product numberAA000CT6
Product descriptionA66
Packaging200mg
Price$451
Updated2026-05-25
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Manufactureraablocks
Product numberAA000CT6
Product descriptionA66
Packaging10mg
Price$81
Updated2026-05-25
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Manufactureraablocks
Product numberAA000CT6
Product descriptionA66
Packaging5mg
Price$57
Updated2026-05-25
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Manufactureraablocks
Product numberAA000CT6
Product descriptionA66
Packaging2mg
Price$44
Updated2026-05-25
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Manufactureraablocks
Product numberAA000CT6
Product descriptionA66 ≥98%
Packaging1mg
Price$32
Updated2026-05-25
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ManufacturerACHEMBLOCK
Product numberP50940
Product descriptionA66 98%
Packaging100MG
Price$460
Updated2026-05-27
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ManufacturerACHEMBLOCK
Product numberP50940
Product descriptionA66 98%
Packaging25MG
Price$175
Updated2026-05-27
Buy

ManufacturerAK Scientific
Product numberX7447
Product description(2S)-N1-(5-(2-tert-butylthiazol-4-yl)-4-methylthiazol-2-yl)pyrrolidine-1,2-dicarboxamide
Packaging10mg
Price$218
Updated2021-12-16
Buy

ManufacturerAK Scientific
Product numberX7447
Product description(2S)-N1-(5-(2-tert-butylthiazol-4-yl)-4-methylthiazol-2-yl)pyrrolidine-1,2-dicarboxamide
Packaging50mg
Price$640
Updated2021-12-16
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ManufacturerAmbeed
Product numberA102947
Product descriptionA66 98+%
Packaging50mg
Price$622
Updated2021-12-16
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ManufacturerAmbeed
Product numberA102947
Product descriptionA66 98+%
Packaging10mg
Price$203
Updated2021-12-16
Buy

ManufacturerAmbeed
Product numberA102947
Product descriptionA66 98+%
Packaging5mg
Price$135
Updated2021-12-16
Buy

ManufacturerAmbeed
Product numberA102947
Product descriptionA66 98+%
Packaging1mg
Price$44
Updated2021-12-16
Buy

Manufacturer	Product number	Product description	Packaging	Price	Updated	Buy
aablocks	AA000CT6	A66 98%	25mg	$102	2026-05-25	Buy
aablocks	AA000CT6	A66 98%	50mg	$172	2026-05-25	Buy
aablocks	AA000CT6	A66	100mg	$327	2026-05-25	Buy
aablocks	AA000CT6	A66	200mg	$451	2026-05-25	Buy
aablocks	AA000CT6	A66	10mg	$81	2026-05-25	Buy
aablocks	AA000CT6	A66	5mg	$57	2026-05-25	Buy
aablocks	AA000CT6	A66	2mg	$44	2026-05-25	Buy
aablocks	AA000CT6	A66 ≥98%	1mg	$32	2026-05-25	Buy
ACHEMBLOCK	P50940	A66 98%	100MG	$460	2026-05-27	Buy
ACHEMBLOCK	P50940	A66 98%	25MG	$175	2026-05-27	Buy
AK Scientific	X7447	(2S)-N1-(5-(2-tert-butylthiazol-4-yl)-4-methylthiazol-2-yl)pyrrolidine-1,2-dicarboxamide	10mg	$218	2021-12-16	Buy
AK Scientific	X7447	(2S)-N1-(5-(2-tert-butylthiazol-4-yl)-4-methylthiazol-2-yl)pyrrolidine-1,2-dicarboxamide	50mg	$640	2021-12-16	Buy
Ambeed	A102947	A66 98+%	50mg	$622	2021-12-16	Buy
Ambeed	A102947	A66 98+%	10mg	$203	2021-12-16	Buy
Ambeed	A102947	A66 98+%	5mg	$135	2021-12-16	Buy
Ambeed	A102947	A66 98+%	1mg	$44	2021-12-16	Buy

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Properties

Density :1.354
storage temp. :Sealed in dry,Store in freezer, under -20°C
solubility :insoluble in H2O; ≥19.7 mg/mL in DMSO; ≥2.63 mg/mL in EtOH with gentle warming
form :solid
pka :6.27±0.70(Predicted)
color :Off-white to light yellow

Safety Information

Symbol(GHS):

Signal word:

Warning

Hazard statements:

Code	Hazard statements	Hazard class	Category	Signal word	Pictogram	P-Codes
H302	Harmful if swallowed	Acute toxicity,oral	Category 4	Warning		P264, P270, P301+P312, P330, P501

Precautionary statements:

P280	Wear protective gloves/protective clothing/eye protection/face protection.
P305+P351+P338	IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continuerinsing.

Description

A-66 is a potent, selective inhibitor of the PI3K isoform p110α (IC₅₀ = 32 nM in a cell-free assay). It displays over 100-fold selectivity for p110α over other isoforms. A-66 is effective in vivo, suppressing the growth of SK-OV-3 tumor xenografts in mice. It also impairs all measures of in vivo insulin action in mice. A-66 partially suppresses B cell receptor-dependent Akt activation and proliferation.

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Suppliers and manufacturers

Shanghai Boyle Chemical Co., Ltd. Chembest Research Laboratories Limited Jinan Trio PharmaTech Co., Ltd. Dalian Meilun Biotech Co., Ltd. China Kouting Group Limited Haoyuan Chemexpress Co., Ltd. Shanghai Aladdin Bio-Chem Technology Co.,LTD Nanjing Dulai Biotechnology Co., Ltd. AdooQ BioScience, LLC ShangHai Caerulum Pharma Discovery Co., Ltd.

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A66

Properties

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Description

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