AZ 12216052
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- $42 - $2400
- Product name: AZ 12216052
- CAS: 1290628-31-7
- MF: C19H22BrNOS
- MW: 392.35308
- EINECS:
- MDL Number:MFCD20926426
- Synonyms:AZ 12216052;2-[[(4-Bromophenyl)methyl]thio]-N-[4-(1-methylpropyl)phenyl]acetamide;AZ12216052 >=98% (HPLC);Acetamide, 2-[[(4-bromophenyl)methyl]thio]-N-[4-(1-methylpropyl)phenyl]-;2-((4-Bromobenzyl)thio)-N-(4-(sec-butyl)phenyl)acetamide
32 prices
Selected condition:
Brand
- aablocks
- ACHEMBLOCK
- AK Scientific
- American Custom Chemicals Corporation
- Axon Medchem
- Biosynth
- Cayman Chemical
- ChemScene
- DC Chemicals
- Tocris
- TRC
- Usbiological
Package
- 10
- 1mg
- 2mg
- 50
- 5mg
- 10mg
- 25mg
- 50mg
- 100mg
- 250MG
- 1g
- Manufactureraablocks
- Product numberAA00A1CN
- Product description2-((4-Bromobenzyl)thio)-N-(4-(sec-butyl)phenyl)acetamide ≥98%
- Packaging1mg
- Price$42
- Updated2026-05-28
- Buy
- Manufactureraablocks
- Product numberAA00A1CN
- Product description2-((4-Bromobenzyl)thio)-N-(4-(sec-butyl)phenyl)acetamide
- Packaging2mg
- Price$56
- Updated2026-05-28
- Buy
- Manufactureraablocks
- Product numberAA00A1CN
- Product description2-((4-Bromobenzyl)thio)-N-(4-(sec-butyl)phenyl)acetamide
- Packaging5mg
- Price$80
- Updated2026-05-28
- Buy
- Manufactureraablocks
- Product numberAA00A1CN
- Product description2-((4-Bromobenzyl)thio)-N-(4-(sec-butyl)phenyl)acetamide 98%
- Packaging10mg
- Price$101
- Updated2026-05-28
- Buy
- Manufactureraablocks
- Product numberAA00A1CN
- Product description2-((4-Bromobenzyl)thio)-N-(4-(sec-butyl)phenyl)acetamide
- Packaging25mg
- Price$187
- Updated2026-05-28
- Buy
- Manufactureraablocks
- Product numberAA00A1CN
- Product description2-((4-Bromobenzyl)thio)-N-(4-(sec-butyl)phenyl)acetamide
- Packaging50mg
- Price$268
- Updated2026-05-28
- Buy
- Manufactureraablocks
- Product numberAA00A1CN
- Product description2-((4-Bromobenzyl)thio)-N-(4-(sec-butyl)phenyl)acetamide
- Packaging100mg
- Price$372
- Updated2026-05-28
- Buy
- ManufacturerACHEMBLOCK
- Product numberAD264636
- Product descriptionAZ12216052 98%
- Packaging25MG
- Price$250
- Updated2026-05-27
- Buy
- ManufacturerACHEMBLOCK
- Product numberAD264636
- Product descriptionAZ12216052 98%
- Packaging100MG
- Price$525
- Updated2026-05-27
- Buy
- ManufacturerACHEMBLOCK
- Product numberAD264636
- Product descriptionAZ12216052 98%
- Packaging250MG
- Price$1050
- Updated2026-05-27
- Buy
- ManufacturerAK Scientific
- Product number7587DW
- Product description2-[(4-Bromophenyl)methylsulfanyl]-N-(4-butan-2-ylphenyl)acetamide
- Packaging5mg
- Price$212
- Updated2021-12-16
- Buy
- ManufacturerAK Scientific
- Product number7587DW
- Product description2-[(4-Bromophenyl)methylsulfanyl]-N-(4-butan-2-ylphenyl)acetamide
- Packaging1mg
- Price$140
- Updated2021-12-16
- Buy
- ManufacturerAmerican Custom Chemicals Corporation
- Product numberINB0004379
- Product descriptionAZ-12216052 98.00%
- Packaging10MG
- Price$260.4
- Updated2021-12-16
- Buy
- ManufacturerAmerican Custom Chemicals Corporation
- Product numberINB0004379
- Product descriptionAZ-12216052 98.00%
- Packaging50MG
- Price$1216.22
- Updated2021-12-16
- Buy
- ManufacturerAxon Medchem
- Product numberAxon1747
- Product descriptionAZ 12216052
- Packaging50mg
- Price$495
- Updated2026-05-19
- Buy
- ManufacturerAxon Medchem
- Product numberAxon1747
- Product descriptionAZ 12216052
- Packaging10mg
- Price$132
- Updated2026-05-19
- Buy
| Manufacturer | Product number | Product description | Packaging | Price | Updated | Buy |
|---|---|---|---|---|---|---|
| aablocks | AA00A1CN | 2-((4-Bromobenzyl)thio)-N-(4-(sec-butyl)phenyl)acetamide ≥98% | 1mg | $42 | 2026-05-28 | Buy |
| aablocks | AA00A1CN | 2-((4-Bromobenzyl)thio)-N-(4-(sec-butyl)phenyl)acetamide | 2mg | $56 | 2026-05-28 | Buy |
| aablocks | AA00A1CN | 2-((4-Bromobenzyl)thio)-N-(4-(sec-butyl)phenyl)acetamide | 5mg | $80 | 2026-05-28 | Buy |
| aablocks | AA00A1CN | 2-((4-Bromobenzyl)thio)-N-(4-(sec-butyl)phenyl)acetamide 98% | 10mg | $101 | 2026-05-28 | Buy |
| aablocks | AA00A1CN | 2-((4-Bromobenzyl)thio)-N-(4-(sec-butyl)phenyl)acetamide | 25mg | $187 | 2026-05-28 | Buy |
| aablocks | AA00A1CN | 2-((4-Bromobenzyl)thio)-N-(4-(sec-butyl)phenyl)acetamide | 50mg | $268 | 2026-05-28 | Buy |
| aablocks | AA00A1CN | 2-((4-Bromobenzyl)thio)-N-(4-(sec-butyl)phenyl)acetamide | 100mg | $372 | 2026-05-28 | Buy |
| ACHEMBLOCK | AD264636 | AZ12216052 98% | 25MG | $250 | 2026-05-27 | Buy |
| ACHEMBLOCK | AD264636 | AZ12216052 98% | 100MG | $525 | 2026-05-27 | Buy |
| ACHEMBLOCK | AD264636 | AZ12216052 98% | 250MG | $1050 | 2026-05-27 | Buy |
| AK Scientific | 7587DW | 2-[(4-Bromophenyl)methylsulfanyl]-N-(4-butan-2-ylphenyl)acetamide | 5mg | $212 | 2021-12-16 | Buy |
| AK Scientific | 7587DW | 2-[(4-Bromophenyl)methylsulfanyl]-N-(4-butan-2-ylphenyl)acetamide | 1mg | $140 | 2021-12-16 | Buy |
| American Custom Chemicals Corporation | INB0004379 | AZ-12216052 98.00% | 10MG | $260.4 | 2021-12-16 | Buy |
| American Custom Chemicals Corporation | INB0004379 | AZ-12216052 98.00% | 50MG | $1216.22 | 2021-12-16 | Buy |
| Axon Medchem | Axon1747 | AZ 12216052 | 50mg | $495 | 2026-05-19 | Buy |
| Axon Medchem | Axon1747 | AZ 12216052 | 10mg | $132 | 2026-05-19 | Buy |
Properties
Boiling point :526.9±45.0 °C(Predicted)
Density :1.323±0.06 g/cm3(Predicted)
storage temp. :Store at -20°C
solubility :DMSO: soluble
form :A crystalline solid
pka :13.70±0.70(Predicted)
color :White to off-white
Density :1.323±0.06 g/cm3(Predicted)
storage temp. :Store at -20°C
solubility :DMSO: soluble
form :A crystalline solid
pka :13.70±0.70(Predicted)
color :White to off-white
Safety Information
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Description
AZ 12216052 is a positive allosteric modulator of metabotropic glutamate receptor 8 (mGluR8). It potentiates glutamate-induced [35S]GTPγS binding in GHEK cells expressing human mGluR8b (EC50 = 1 μM). In a cell-based model of Parkinson’s disease, AZ 12216052 inhibits MPP+-induced decreases in the viability of undifferentiated SH-SY5Y cells when used at concentrations ranging from 0.001 to 1 μM and in retinoic acid-differentiated SH-SY5Y cells at 0.1 and 1 μM. AZ 12216052 (10 mg/kg) increases the time spent in the open areas of the elevated zero maze and reduces the acoustic startle response in mice, indicating anxiolytic-like activity in response to avoidable and unavoidable anxiogenic stimuli, respectively.Related product price
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