BAY-1125976.
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- $35 - $2476
- Product name: BAY-1125976.
- CAS: 1402608-02-9
- MF: C23H21N5O
- MW: 383.45
- EINECS:
- MDL Number:MFCD30481340
- Synonyms:2-[4-(1-Aminocyclobutyl)phenyl]-3-phenylimidazo[1,2-b]pyridazine-6-carboxamide;BAY-1125976; BAY 1125976;CS-2913;BAY 1125976;BAY1125976;BAY-1125976.;Imidazo[1,2-b]pyridazine-6-carboxamide, 2-[4-(1-aminocyclobutyl)phenyl]-3-phenyl-;inhibit,Inhibitor,Protein kinase B,Akt,BAY 1125976,BAY1125976,PKB,BAY-1125976
30 prices
Selected condition：
Brand
- aablocks
- AK Scientific
- Biosynth
- Cayman Chemical
- ChemScene
- Crysdot
- DC Chemicals
Package
- 1mg
- 2mg
- 5mg
- 10mg
- 25mg
- 50mg
- 100mg
- 250mg
- 500mg
- 1g
- Manufactureraablocks
- Product numberAA001C5B
- Product description2-(4-(1-Aminocyclobutyl)phenyl)-3-phenylimidazo[1,2-b]pyridazine-6-carboxamide 98%
- Packaging2mg
- Price$35
- Updated2026-05-28
- Buy
- Manufactureraablocks
- Product numberAA001C5B
- Product description2-(4-(1-Aminocyclobutyl)phenyl)-3-phenylimidazo[1,2-b]pyridazine-6-carboxamide 98%
- Packaging5mg
- Price$58
- Updated2026-05-28
- Buy
- Manufactureraablocks
- Product numberAA001C5B
- Product description2-(4-(1-Aminocyclobutyl)phenyl)-3-phenylimidazo[1,2-b]pyridazine-6-carboxamide 98%
- Packaging25mg
- Price$135
- Updated2026-05-28
- Buy
- Manufactureraablocks
- Product numberAA001C5B
- Product description2-(4-(1-Aminocyclobutyl)phenyl)-3-phenylimidazo[1,2-b]pyridazine-6-carboxamide 98%
- Packaging10mg
- Price$98
- Updated2026-05-28
- Buy
- Manufactureraablocks
- Product numberAA001C5B
- Product description2-(4-(1-Aminocyclobutyl)phenyl)-3-phenylimidazo[1,2-b]pyridazine-6-carboxamide 98%
- Packaging50mg
- Price$229
- Updated2026-05-28
- Buy
- Manufactureraablocks
- Product numberAA001C5B
- Product description2-(4-(1-Aminocyclobutyl)phenyl)-3-phenylimidazo[1,2-b]pyridazine-6-carboxamide 98%
- Packaging100mg
- Price$388
- Updated2026-05-28
- Buy
- ManufacturerAK Scientific
- Product number2002DU
- Product description2-[4-(1-Aminocyclobutyl)phenyl]-3-phenylimidazo[1,2-b]pyridazine-6-carboxamide
- Packaging5mg
- Price$252
- Updated2021-12-16
- Buy
- ManufacturerBiosynth
- Product numberCGC60802
- Product descriptionBAY1125976
- Packaging5mg
- Price$322.4
- Updated2026-06-04
- Buy
- ManufacturerBiosynth
- Product numberCGC60802
- Product descriptionBAY1125976
- Packaging10mg
- Price$515.7
- Updated2026-06-04
- Buy
- ManufacturerBiosynth
- Product numberCGC60802
- Product descriptionBAY1125976
- Packaging25mg
- Price$967
- Updated2026-06-04
- Buy
- ManufacturerBiosynth
- Product numberCGC60802
- Product descriptionBAY1125976
- Packaging50mg
- Price$1547
- Updated2026-06-04
- Buy
- ManufacturerBiosynth
- Product numberCGC60802
- Product descriptionBAY1125976
- Packaging100mg
- Price$2476
- Updated2026-06-04
- Buy
- ManufacturerCayman Chemical
- Product number28913
- Product descriptionBAY-1125976 ≥98%
- Packaging25mg
- Price$587
- Updated2026-04-30
- Buy
- ManufacturerCayman Chemical
- Product number28913
- Product descriptionBAY-1125976 ≥98%
- Packaging10mg
- Price$268
- Updated2026-04-30
- Buy
- ManufacturerCayman Chemical
- Product number28913
- Product descriptionBAY-1125976 ≥98%
- Packaging5mg
- Price$153
- Updated2026-04-30
- Buy
- ManufacturerCayman Chemical
- Product number28913
- Product descriptionBAY-1125976 ≥98%
- Packaging1mg
- Price$36
- Updated2026-04-30
- Buy
| Manufacturer | Product number | Product description | Packaging | Price | Updated | Buy |
|---|---|---|---|---|---|---|
| aablocks | AA001C5B | 2-(4-(1-Aminocyclobutyl)phenyl)-3-phenylimidazo[1,2-b]pyridazine-6-carboxamide 98% | 2mg | $35 | 2026-05-28 | Buy |
| aablocks | AA001C5B | 2-(4-(1-Aminocyclobutyl)phenyl)-3-phenylimidazo[1,2-b]pyridazine-6-carboxamide 98% | 5mg | $58 | 2026-05-28 | Buy |
| aablocks | AA001C5B | 2-(4-(1-Aminocyclobutyl)phenyl)-3-phenylimidazo[1,2-b]pyridazine-6-carboxamide 98% | 25mg | $135 | 2026-05-28 | Buy |
| aablocks | AA001C5B | 2-(4-(1-Aminocyclobutyl)phenyl)-3-phenylimidazo[1,2-b]pyridazine-6-carboxamide 98% | 10mg | $98 | 2026-05-28 | Buy |
| aablocks | AA001C5B | 2-(4-(1-Aminocyclobutyl)phenyl)-3-phenylimidazo[1,2-b]pyridazine-6-carboxamide 98% | 50mg | $229 | 2026-05-28 | Buy |
| aablocks | AA001C5B | 2-(4-(1-Aminocyclobutyl)phenyl)-3-phenylimidazo[1,2-b]pyridazine-6-carboxamide 98% | 100mg | $388 | 2026-05-28 | Buy |
| AK Scientific | 2002DU | 2-[4-(1-Aminocyclobutyl)phenyl]-3-phenylimidazo[1,2-b]pyridazine-6-carboxamide | 5mg | $252 | 2021-12-16 | Buy |
| Biosynth | CGC60802 | BAY1125976 | 5mg | $322.4 | 2026-06-04 | Buy |
| Biosynth | CGC60802 | BAY1125976 | 10mg | $515.7 | 2026-06-04 | Buy |
| Biosynth | CGC60802 | BAY1125976 | 25mg | $967 | 2026-06-04 | Buy |
| Biosynth | CGC60802 | BAY1125976 | 50mg | $1547 | 2026-06-04 | Buy |
| Biosynth | CGC60802 | BAY1125976 | 100mg | $2476 | 2026-06-04 | Buy |
| Cayman Chemical | 28913 | BAY-1125976 ≥98% | 25mg | $587 | 2026-04-30 | Buy |
| Cayman Chemical | 28913 | BAY-1125976 ≥98% | 10mg | $268 | 2026-04-30 | Buy |
| Cayman Chemical | 28913 | BAY-1125976 ≥98% | 5mg | $153 | 2026-04-30 | Buy |
| Cayman Chemical | 28913 | BAY-1125976 ≥98% | 1mg | $36 | 2026-04-30 | Buy |
Properties
storage temp. :Store at -20°C
solubility :DMSO:13.0(Max Conc. mg/mL);33.9(Max Conc. mM)
DMF:5.0(Max Conc. mg/mL);13.04(Max Conc. mM)
DMF:PBS (pH 7.2) (1:3):0.25(Max Conc. mg/mL);0.65(Max Conc. mM) form :A crystalline solid
color :Light yellow to yellow
InChI :InChI=1S/C23H21N5O/c24-22(29)18-11-12-19-26-20(21(28(19)27-18)16-5-2-1-3-6-16)15-7-9-17(10-8-15)23(25)13-4-14-23/h1-3,5-12H,4,13-14,25H2,(H2,24,29)
InChIKey :JBGYKRAZYDNCNV-UHFFFAOYSA-N
SMILES :C12=NC(C3=CC=C(C4(N)CCC4)C=C3)=C(C3=CC=CC=C3)N1N=C(C(N)=O)C=C2
solubility :DMSO:13.0(Max Conc. mg/mL);33.9(Max Conc. mM)
DMF:5.0(Max Conc. mg/mL);13.04(Max Conc. mM)
DMF:PBS (pH 7.2) (1:3):0.25(Max Conc. mg/mL);0.65(Max Conc. mM) form :A crystalline solid
color :Light yellow to yellow
InChI :InChI=1S/C23H21N5O/c24-22(29)18-11-12-19-26-20(21(28(19)27-18)16-5-2-1-3-6-16)15-7-9-17(10-8-15)23(25)13-4-14-23/h1-3,5-12H,4,13-14,25H2,(H2,24,29)
InChIKey :JBGYKRAZYDNCNV-UHFFFAOYSA-N
SMILES :C12=NC(C3=CC=C(C4(N)CCC4)C=C3)=C(C3=CC=CC=C3)N1N=C(C(N)=O)C=C2
Safety Information
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Description
BAY-1125976 is an allosteric inhibitor of Akt1 and -2 (IC50s = 5.2 and 18 nM, respectively, in a time-resolved FRET assay). It is selective for Akt1 and -2 over Akt3 (IC50 = 427 nM in the same assay) but does inhibit the activity of the receptor tyrosine kinases FLT1, -3, -4, and Mer by greater than 50% in a panel of 227 kinases at 1 μM. BAY-1125976 inhibits the proliferation of 23 cancer cell lines (IC50s = 0.02-10 μM) and reduces tumor growth in KPL-4, MCF-7, and patient-derived xenograft (PDX) mouse models when administered at a dose of 50 mg/kg per day.Suppliers and manufacturers
Nantong Hi-Future Biotechnology Co., Ltd
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Hubei Chuangliankangcheng Pharmaceutical Co., Ltd.
Shanghai EFE Biological Technology Co., Ltd.
Shanghai YuanYe Biotechnology Co., Ltd.
ShangHai Biochempartner Co.,Ltd
Shanghai Rechem science Co., Ltd.