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ChemicalBook >> CAS DataBase List >> DBCO-NHS Ester

DBCO-NHS Ester

DBCO-NHS Ester price.
  • $16 - $29980
  • Product name: DBCO-NHS Ester
  • CAS: 1353016-71-3
  • MF: C23H18N2O5
  • MW: 402.4
  • EINECS:-0
  • MDL Number:MFCD24386367
  • Synonyms:N-Succinimidyl 4-[(5-Aza-3,4:7,8-dibenzocyclooct-1-yne)-5-yl]-4-oxobutyrate;DBCO-NHS ester (DBCO NHS ester);11,12-Didehydro-γ-oxo-dibenz[b,f]azocine-5(6H)-butanoic acid 2,5-dioxo-1-pyrrolidinyl ester;CAS_1353016-71-3;Dibenz[b,f]azocine-5(6H)-butanoic acid, 11,12-didehydro-γ-oxo-, 2,5-dioxo-1-pyrrolidinyl ester;4-[(5-aza-3，4:7，8-dibenzocyclooctan-1-yne)-5-yl]-4-oxobutyrate-n-succinimide;Dibenz[b,?f]azocine-5(6H)-butanoic acid,11,12-didehydro-γ-oxo-,2,5-dioxo-1-pyrrolidinyl ester （DBCO-NHS）;DBCO-NHS ester
Price68 Properties Safety Information Description
68 prices
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Brand
  • aablocks
  • ACHEMBLOCK
  • AK Scientific
  • Arctom
  • Biosynth
  • BroadPharm
  • Cayman Chemical
  • Chemenu
  • Chem-Impex
  • ChemPep
  • ChemScene
  • Crysdot
  • dPEG
  • JR MediChem
  • TRC
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  • 0.025g
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  • 1g
  • 5g
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  • Manufactureraablocks
  • Product numberAA009ZT7
  • Product description11,12-Didehydro-γ-oxo-dibenz[b,f]azocine-5(6H)-butanoic acid 2,5-dioxo-1-pyrrolidinyl ester 98%
  • Packaging50mg
  • Price$16
  • Updated2026-05-28
  • Buy
  • Manufactureraablocks
  • Product numberAA009ZT7
  • Product description11,12-Didehydro-γ-oxo-dibenz[b,f]azocine-5(6H)-butanoic acid 2,5-dioxo-1-pyrrolidinyl ester 98%
  • Packaging100mg
  • Price$22
  • Updated2026-05-28
  • Buy
  • Manufactureraablocks
  • Product numberAA009ZT7
  • Product description11,12-Didehydro-γ-oxo-dibenz[b,f]azocine-5(6H)-butanoic acid 2,5-dioxo-1-pyrrolidinyl ester 98%
  • Packaging250mg
  • Price$42
  • Updated2026-05-28
  • Buy
  • Manufactureraablocks
  • Product numberAA009ZT7
  • Product description11,12-Didehydro-γ-oxo-dibenz[b,f]azocine-5(6H)-butanoic acid 2,5-dioxo-1-pyrrolidinyl ester 95%
  • Packaging500mg
  • Price$77
  • Updated2026-05-28
  • Buy
  • Manufactureraablocks
  • Product numberAA009ZT7
  • Product description11,12-Didehydro-γ-oxo-dibenz[b,f]azocine-5(6H)-butanoic acid 2,5-dioxo-1-pyrrolidinyl ester 98%
  • Packaging1g
  • Price$91
  • Updated2026-05-28
  • Buy
  • Manufactureraablocks
  • Product numberAA009ZT7
  • Product description11,12-Didehydro-γ-oxo-dibenz[b,f]azocine-5(6H)-butanoic acid 2,5-dioxo-1-pyrrolidinyl ester 98%
  • Packaging5g
  • Price$298
  • Updated2026-05-28
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  • ManufacturerACHEMBLOCK
  • Product numberQ69946
  • Product descriptionDibenzocyclooctyne-n-hydroxysuccinimidyl ester 95%
  • Packaging1G
  • Price$340
  • Updated2026-05-27
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  • ManufacturerACHEMBLOCK
  • Product numberQ69946
  • Product descriptionDibenzocyclooctyne-n-hydroxysuccinimidyl ester 95%
  • Packaging250MG
  • Price$110
  • Updated2026-05-27
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  • ManufacturerACHEMBLOCK
  • Product numberQ69946
  • Product descriptionDibenzocyclooctyne-n-hydroxysuccinimidyl ester 95%
  • Packaging5G
  • Price$1330
  • Updated2026-05-27
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  • ManufacturerAK Scientific
  • Product number0331DY
  • Product descriptionDbco-nhs
  • Packaging1g
  • Price$1788
  • Updated2021-12-16
  • Buy
  • ManufacturerArctom
  • Product numberHY-42973
  • Product descriptionDBCO-NHSester 99.39%
  • Packaging500mg
  • Price$546
  • Updated2026-05-26
  • Buy
  • ManufacturerArctom
  • Product numberHY-42973
  • Product descriptionDBCO-NHSester 99.39%
  • Packaging10mg
  • Price$92
  • Updated2026-05-26
  • Buy
  • ManufacturerArctom
  • Product numberHY-42973
  • Product descriptionDBCO-NHSester 99.39%
  • Packaging5mg
  • Price$57
  • Updated2026-05-26
  • Buy
  • ManufacturerArctom
  • Product numberHY-42973
  • Product descriptionDBCO-NHSester 99.39%
  • Packaging100mg
  • Price$291
  • Updated2026-05-26
  • Buy
  • ManufacturerArctom
  • Product numberHY-42973
  • Product descriptionDBCO-NHSester 99.39%
  • Packaging250mg
  • Price$405
  • Updated2026-05-26
  • Buy
  • ManufacturerArctom
  • Product numberHY-42973
  • Product descriptionDBCO-NHSester 99.39%
  • Packaging50mg
  • Price$224
  • Updated2026-05-26
  • Buy
Manufacturer Product number Product description Packaging Price Updated Buy
aablocks AA009ZT7 11,12-Didehydro-γ-oxo-dibenz[b,f]azocine-5(6H)-butanoic acid 2,5-dioxo-1-pyrrolidinyl ester 98% 50mg $16 2026-05-28 Buy
aablocks AA009ZT7 11,12-Didehydro-γ-oxo-dibenz[b,f]azocine-5(6H)-butanoic acid 2,5-dioxo-1-pyrrolidinyl ester 98% 100mg $22 2026-05-28 Buy
aablocks AA009ZT7 11,12-Didehydro-γ-oxo-dibenz[b,f]azocine-5(6H)-butanoic acid 2,5-dioxo-1-pyrrolidinyl ester 98% 250mg $42 2026-05-28 Buy
aablocks AA009ZT7 11,12-Didehydro-γ-oxo-dibenz[b,f]azocine-5(6H)-butanoic acid 2,5-dioxo-1-pyrrolidinyl ester 95% 500mg $77 2026-05-28 Buy
aablocks AA009ZT7 11,12-Didehydro-γ-oxo-dibenz[b,f]azocine-5(6H)-butanoic acid 2,5-dioxo-1-pyrrolidinyl ester 98% 1g $91 2026-05-28 Buy
aablocks AA009ZT7 11,12-Didehydro-γ-oxo-dibenz[b,f]azocine-5(6H)-butanoic acid 2,5-dioxo-1-pyrrolidinyl ester 98% 5g $298 2026-05-28 Buy
ACHEMBLOCK Q69946 Dibenzocyclooctyne-n-hydroxysuccinimidyl ester 95% 1G $340 2026-05-27 Buy
ACHEMBLOCK Q69946 Dibenzocyclooctyne-n-hydroxysuccinimidyl ester 95% 250MG $110 2026-05-27 Buy
ACHEMBLOCK Q69946 Dibenzocyclooctyne-n-hydroxysuccinimidyl ester 95% 5G $1330 2026-05-27 Buy
AK Scientific 0331DY Dbco-nhs 1g $1788 2021-12-16 Buy
Arctom HY-42973 DBCO-NHSester 99.39% 500mg $546 2026-05-26 Buy
Arctom HY-42973 DBCO-NHSester 99.39% 10mg $92 2026-05-26 Buy
Arctom HY-42973 DBCO-NHSester 99.39% 5mg $57 2026-05-26 Buy
Arctom HY-42973 DBCO-NHSester 99.39% 100mg $291 2026-05-26 Buy
Arctom HY-42973 DBCO-NHSester 99.39% 250mg $405 2026-05-26 Buy
Arctom HY-42973 DBCO-NHSester 99.39% 50mg $224 2026-05-26 Buy
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Properties

Boiling point :670.2±65.0 °C(Predicted)
Density :1.43±0.1 g/cm3(Predicted)
storage temp. :Storage temp. -20°C
solubility :Soluble in DMSO, DCM, DMF
pka :-0.23±0.20(Predicted)
form :Solid
color :White to Off-White
Appearance :White solid
Stability :Moisture Sensitive
InChI :InChI=1S/C23H18N2O5/c26-20(13-14-23(29)30-25-21(27)11-12-22(25)28)24-15-18-7-2-1-5-16(18)9-10-17-6-3-4-8-19(17)24/h1-8H,11-15H2
InChIKey :XCEBOJWFQSQZKR-UHFFFAOYSA-N
SMILES :C(N1CC2=CC=CC=C2C#CC2=CC=CC=C12)(=O)CCC(=O)ON1C(CCC1=O)=O

Safety Information

Symbol(GHS): Exclamation Mark (GHS07)
Signal word: Warning
Hazard statements:
Code Hazard statements Hazard class Category Signal word Pictogram P-Codes
H315 Causes skin irritation Skin corrosion/irritation Category 2 Warning P264, P280, P302+P352, P321,P332+P313, P362
H319 Causes serious eye irritation Serious eye damage/eye irritation Category 2A Warning P264, P280, P305+P351+P338,P337+P313P
H335 May cause respiratory irritation Specific target organ toxicity, single exposure;Respiratory tract irritation Category 3 Warning
Precautionary statements:
P261 Avoid breathing dust/fume/gas/mist/vapours/spray.
P305+P351+P338 IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continuerinsing.

Description

DBCO-NHS Ester is a very popular amine-reactive click chemistry reagent. It can be used to modify an amine-containing molecule in organic solvents (limited solubility in aqueous media). It reacts with primary amines such as the side chain of lysine residues or aminosilane-coated surfaces at neutral or slightly basic pH to form covalent bonds. The low mass weight will add minimal spacer to modified molecules. DBCO is commonly used for copper-free Click Chemistry reactions.

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Suppliers and manufacturers

Shaanxi Xinyan Bomei Biotechnology Co., Ltd. Shanghai Send Pharmaceutical Technology Co., Ltd. Shanghai Huasige Pharmaceutical Technology Co., LTD Shanghai Huici Pharmaceutical Technology Co., LTD Henan Mengtai Pharmaceutical Technology Co., Ltd Chemyouth Life Science（Suzhou）Co.,Ltd Shijiazhuang Qihengyun Biotechnology Co., Ltd Suzhou Highfine Biotech Co., Ltd PharmaBlock Sciences (Nanjing),Inc. Biomatrik (Jiaxing) Inc.