Mpep hydrochloride
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- $10 - $2080
- Product name: Mpep hydrochloride
- CAS: 219911-35-0
- MF: C14H11N.ClH
- MW: 229.709
- EINECS:
- MDL Number:MFCD02262119
- Synonyms:MPEP hydrochloride/219911-35-0/99% purity with low price in stock;MPEP Hydrochloride, >98%;6-methyl-2-(phenylethynyl)pyridine;2-methyl-6-(phenylethynyl)pyridine(MPEP);Pyridine, 6-methyl-2-(phenylethynyl)-;6-Methyl-2-(phenylethynyl)pyridine hydrochloride;Pyridine,2-methyl-6-(2-phenylethynyl)-, hydrochloride (1:1);MPVP replace pvp,White Crystal, New Stock!
51 prices
Selected condition：
Brand
- aablocks
- ACHEMBLOCK
- AK Scientific
- Ambeed
- ApexBio Technology
- Arctom
- AvaChem
- Axon Medchem
- Biosynth
- Cayman Chemical
- ChemScene
- Crysdot
- DC Chemicals
- Matrix Scientific
- Medical Isotopes, Inc.
- Sigma-Aldrich
- TRC
- Usbiological
Package
- 10mM*1mLinDMSO(Solid+Solvent)
- 10mg
- 25mg
- 50mg
- 1mg
- 5mg
- 100.00mg
- 10mM*1mLinDMSO(Solution)
- 100mg
- 250.00mg
- 250MG
- 500mg
- 1.00g
- 1G
- 5g
- Manufactureraablocks
- Product numberAA00BE8A
- Product description2-Methyl-6-(phenylethynyl)pyridine hydrochloride 98%
- Packaging10mg
- Price$12
- Updated2026-05-28
- Buy
- Manufactureraablocks
- Product numberAA00BE8A
- Product description2-Methyl-6-(phenylethynyl)pyridine hydrochloride 98%
- Packaging1mg
- Price$10
- Updated2026-05-28
- Buy
- ManufacturerACHEMBLOCK
- Product numberO33932
- Product descriptionMPEP hydrochloride 98%
- Packaging250MG
- Price$140
- Updated2026-05-27
- Buy
- ManufacturerACHEMBLOCK
- Product numberO33932
- Product descriptionMPEP hydrochloride 98%
- Packaging1G
- Price$420
- Updated2026-05-27
- Buy
- ManufacturerAK Scientific
- Product numberY0463
- Product description2-Methyl-6-(phenylethynyl)pyridinehydrochloride
- Packaging5g
- Price$2080
- Updated2021-12-16
- Buy
- ManufacturerAmbeed
- Product numberA303368
- Product description2-Methyl-6-(phenylethynyl)pyridinehydrochloride 98+%
- Packaging50mg
- Price$148
- Updated2021-12-16
- Buy
- ManufacturerAmbeed
- Product numberA303368
- Product description2-Methyl-6-(phenylethynyl)pyridinehydrochloride 98+%
- Packaging10mg
- Price$68
- Updated2021-12-16
- Buy
- ManufacturerAmbeed
- Product numberA303368
- Product description2-Methyl-6-(phenylethynyl)pyridinehydrochloride 98+%
- Packaging25mg
- Price$114
- Updated2021-12-16
- Buy
- ManufacturerApexBio Technology
- Product numberA3633
- Product descriptionMPEP Hydrochloride
- Packaging10mg
- Price$56
- Updated2026-05-06
- Buy
- ManufacturerApexBio Technology
- Product numberA3633
- Product descriptionMPEP Hydrochloride
- Packaging50mg
- Price$212
- Updated2026-05-06
- Buy
- ManufacturerArctom
- Product numberAS513445
- Product description2-Methyl-6-(phenylethynyl)pyridinehydrochloride
- Packaging50mg
- Price$147
- Updated2021-12-16
- Buy
- ManufacturerArctom
- Product numberHY-14609
- Product descriptionMPEPHydrochloride 99.82%
- Packaging100mg
- Price$257
- Updated2026-05-26
- Buy
- ManufacturerArctom
- Product numberHY-14609
- Product descriptionMPEPHydrochloride 99.82%
- Packaging50mg
- Price$162
- Updated2026-05-26
- Buy
- ManufacturerArctom
- Product numberHY-14609
- Product descriptionMPEPHydrochloride 99.82%
- Packaging10mg
- Price$48
- Updated2026-05-26
- Buy
- ManufacturerArctom
- Product numberHY-14609
- Product descriptionMPEPHydrochloride 99.82%
- Packaging5mg
- Price$29
- Updated2026-05-26
- Buy
- ManufacturerArctom
- Product numberHY-14609
- Product descriptionMPEPHydrochloride 99.82%
- Packaging10mM*1mLinDMSO(Solid+Solvent)
- Price$30
- Updated2026-05-26
- Buy
| Manufacturer | Product number | Product description | Packaging | Price | Updated | Buy |
|---|---|---|---|---|---|---|
| aablocks | AA00BE8A | 2-Methyl-6-(phenylethynyl)pyridine hydrochloride 98% | 10mg | $12 | 2026-05-28 | Buy |
| aablocks | AA00BE8A | 2-Methyl-6-(phenylethynyl)pyridine hydrochloride 98% | 1mg | $10 | 2026-05-28 | Buy |
| ACHEMBLOCK | O33932 | MPEP hydrochloride 98% | 250MG | $140 | 2026-05-27 | Buy |
| ACHEMBLOCK | O33932 | MPEP hydrochloride 98% | 1G | $420 | 2026-05-27 | Buy |
| AK Scientific | Y0463 | 2-Methyl-6-(phenylethynyl)pyridinehydrochloride | 5g | $2080 | 2021-12-16 | Buy |
| Ambeed | A303368 | 2-Methyl-6-(phenylethynyl)pyridinehydrochloride 98+% | 50mg | $148 | 2021-12-16 | Buy |
| Ambeed | A303368 | 2-Methyl-6-(phenylethynyl)pyridinehydrochloride 98+% | 10mg | $68 | 2021-12-16 | Buy |
| Ambeed | A303368 | 2-Methyl-6-(phenylethynyl)pyridinehydrochloride 98+% | 25mg | $114 | 2021-12-16 | Buy |
| ApexBio Technology | A3633 | MPEP Hydrochloride | 10mg | $56 | 2026-05-06 | Buy |
| ApexBio Technology | A3633 | MPEP Hydrochloride | 50mg | $212 | 2026-05-06 | Buy |
| Arctom | AS513445 | 2-Methyl-6-(phenylethynyl)pyridinehydrochloride | 50mg | $147 | 2021-12-16 | Buy |
| Arctom | HY-14609 | MPEPHydrochloride 99.82% | 100mg | $257 | 2026-05-26 | Buy |
| Arctom | HY-14609 | MPEPHydrochloride 99.82% | 50mg | $162 | 2026-05-26 | Buy |
| Arctom | HY-14609 | MPEPHydrochloride 99.82% | 10mg | $48 | 2026-05-26 | Buy |
| Arctom | HY-14609 | MPEPHydrochloride 99.82% | 5mg | $29 | 2026-05-26 | Buy |
| Arctom | HY-14609 | MPEPHydrochloride 99.82% | 10mM*1mLinDMSO(Solid+Solvent) | $30 | 2026-05-26 | Buy |
Properties
Melting point :145-146℃
storage temp. :room temp
solubility :DMSO: 10 mg/mL
form :solid
color :off-white
Stability :Stable for 1 year from date of purchase as supplied. Solutions in DMSO or ethanol may be stored at -20°C for up to 1 month.
InChI :1S/C14H11N.ClH/c1-12-6-5-9-14(15-12)11-10-13-7-3-2-4-8-13;/h2-9H,1H3;1H
InChIKey :PKDHDJBNEKXCBI-UHFFFAOYSA-N
SMILES :Cl.Cc1cccc(n1)C#Cc2ccccc2
storage temp. :room temp
solubility :DMSO: 10 mg/mL
form :solid
color :off-white
Stability :Stable for 1 year from date of purchase as supplied. Solutions in DMSO or ethanol may be stored at -20°C for up to 1 month.
InChI :1S/C14H11N.ClH/c1-12-6-5-9-14(15-12)11-10-13-7-3-2-4-8-13;/h2-9H,1H3;1H
InChIKey :PKDHDJBNEKXCBI-UHFFFAOYSA-N
SMILES :Cl.Cc1cccc(n1)C#Cc2ccccc2
Safety Information
| Symbol(GHS): |
 
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Description
Glutamate, the major excitatory neurotransmitter in the brain, acts on both ionotropic and metabotropic glutamate receptors. Excessive metabotropic glutamate receptor (mGluR) transmission has been linked to epilepsy, ischemia, pain, anxiety, and depression. Eight subtypes (1-8) and multiple splice variants of the mGluR have been identified and grouped based on their pharmacological properties. Group I mGluRs (subtypes 1 and 5) activate the phosphatidyl inositol pathway, while Group II (2 and 3) and Group III (4, 6, 7 and 8) inhibit adenylyl cyclase. MPEP is a potent, highly selective non-competitive antagonist at the mGlu5a receptor subtype (IC50 = 36 nM) while having no agonist or antagonist activities at the mGlu1b receptor at concentrations up to 30 μM. MPEP is centrally active following systemic administration in vivo, inducing anxiolytic-like effects in rodent models of anxiety and depression when administered at 1-30 mg/kg. MPEP has also been reported as a positive allosteric modulator of mGluR4 at μM concentrations.More related product prices
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