Naphthofluorescein
|
- $24 - $969.6
- Product name: Naphthofluorescein
- CAS: 61419-02-1
- MF: C28H16O5
- MW: 432.42
- EINECS:634-716-5
- MDL Number:MFCD00329026
- Synonyms:NAPHTHOFLUORESCEIN, FOR FLUORESCENCE;NAPHTHOFLUORESCEIN FOR FLUORESCENCE 95+%;Naphthafluorescein;Spiro[7H-dibenzo[c,h]xanthene-7,1'(3'H)-isobenzofuran]-3'-one,3,11-dihydroxy-;Naphthofluorescein
27 prices
Selected condition：
Brand
- aablocks
- ACHEMBLOCK
- AK Scientific
- Alichem
- American Custom Chemicals Corporation
- Arctom
- Cayman Chemical
- ChemScene
- Sigma-Aldrich
- TRC
Package
- 1MG
- 5mg
- 10mg
- 25mg
- 50mg
- 100mg
- 250MG
- 500mg
- 1G
- Manufactureraablocks
- Product numberAA00EAI0
- Product description3,11-Dihydroxyspiro[7H-dibenzo[c,h]xanthene-7,1'(3'H)-isobenzofuran]-3'-one ≥98%
- Packaging5mg
- Price$36
- Updated2026-05-28
- Buy
- Manufactureraablocks
- Product numberAA00EAI0
- Product description3,11-Dihydroxyspiro[7H-dibenzo[c,h]xanthene-7,1'(3'H)-isobenzofuran]-3'-one ≥95%(HPLC)
- Packaging25mg
- Price$48
- Updated2026-05-28
- Buy
- Manufactureraablocks
- Product numberAA00EAI0
- Product description3,11-Dihydroxyspiro[7H-dibenzo[c,h]xanthene-7,1'(3'H)-isobenzofuran]-3'-one ≥95%(HPLC)
- Packaging100mg
- Price$149
- Updated2026-05-28
- Buy
- Manufactureraablocks
- Product numberAA00EAI0
- Product description3,11-Dihydroxyspiro[7H-dibenzo[c,h]xanthene-7,1'(3'H)-isobenzofuran]-3'-one ≥95%(HPLC)
- Packaging500mg
- Price$462
- Updated2026-05-28
- Buy
- ManufacturerACHEMBLOCK
- Product numberAD249268
- Product descriptionNaphthofluorescein 98%
- Packaging1G
- Price$595
- Updated2026-05-27
- Buy
- ManufacturerACHEMBLOCK
- Product numberAD249268
- Product descriptionNaphthofluorescein 98%
- Packaging250MG
- Price$230
- Updated2026-05-27
- Buy
- ManufacturerAK Scientific
- Product number1910AH
- Product descriptionNaphthofluorescein
- Packaging10mg
- Price$160
- Updated2021-12-16
- Buy
- ManufacturerAlichem
- Product number61419021
- Product description2-(11-Hydroxy-3-oxo-3H-dibenzo[c,h]xanthen-7-yl)benzoicacid
- Packaging1g
- Price$969.6
- Updated2021-12-16
- Buy
- ManufacturerAmerican Custom Chemicals Corporation
- Product numberFRL0000171
- Product descriptionNAPHTHOFLUORESCEIN 95.00%
- Packaging1MG
- Price$416
- Updated2021-12-16
- Buy
- ManufacturerAmerican Custom Chemicals Corporation
- Product numberFRL0000171
- Product descriptionNAPHTHOFLUORESCEIN 95.00%
- Packaging5MG
- Price$426
- Updated2021-12-16
- Buy
- ManufacturerAmerican Custom Chemicals Corporation
- Product numberFRL0000171
- Product descriptionNAPHTHOFLUORESCEIN 95.00%
- Packaging10MG
- Price$452
- Updated2021-12-16
- Buy
- ManufacturerArctom
- Product numberHY-124473
- Product descriptionNaphthofluorescein 99.02%
- Packaging50mg
- Price$75
- Updated2026-05-26
- Buy
- ManufacturerArctom
- Product numberHY-124473
- Product descriptionNaphthofluorescein 99.02%
- Packaging100mg
- Price$97
- Updated2026-05-26
- Buy
- ManufacturerArctom
- Product numberHY-124473
- Product descriptionNaphthofluorescein 99.02%
- Packaging25mg
- Price$54
- Updated2026-05-26
- Buy
- ManufacturerArctom
- Product numberHY-124473
- Product descriptionNaphthofluorescein 99.02%
- Packaging5mg
- Price$24
- Updated2026-05-26
- Buy
- ManufacturerArctom
- Product numberHY-124473
- Product descriptionNaphthofluorescein 99.02%
- Packaging10mg
- Price$34
- Updated2026-05-26
- Buy
| Manufacturer | Product number | Product description | Packaging | Price | Updated | Buy |
|---|---|---|---|---|---|---|
| aablocks | AA00EAI0 | 3,11-Dihydroxyspiro[7H-dibenzo[c,h]xanthene-7,1'(3'H)-isobenzofuran]-3'-one ≥98% | 5mg | $36 | 2026-05-28 | Buy |
| aablocks | AA00EAI0 | 3,11-Dihydroxyspiro[7H-dibenzo[c,h]xanthene-7,1'(3'H)-isobenzofuran]-3'-one ≥95%(HPLC) | 25mg | $48 | 2026-05-28 | Buy |
| aablocks | AA00EAI0 | 3,11-Dihydroxyspiro[7H-dibenzo[c,h]xanthene-7,1'(3'H)-isobenzofuran]-3'-one ≥95%(HPLC) | 100mg | $149 | 2026-05-28 | Buy |
| aablocks | AA00EAI0 | 3,11-Dihydroxyspiro[7H-dibenzo[c,h]xanthene-7,1'(3'H)-isobenzofuran]-3'-one ≥95%(HPLC) | 500mg | $462 | 2026-05-28 | Buy |
| ACHEMBLOCK | AD249268 | Naphthofluorescein 98% | 1G | $595 | 2026-05-27 | Buy |
| ACHEMBLOCK | AD249268 | Naphthofluorescein 98% | 250MG | $230 | 2026-05-27 | Buy |
| AK Scientific | 1910AH | Naphthofluorescein | 10mg | $160 | 2021-12-16 | Buy |
| Alichem | 61419021 | 2-(11-Hydroxy-3-oxo-3H-dibenzo[c,h]xanthen-7-yl)benzoicacid | 1g | $969.6 | 2021-12-16 | Buy |
| American Custom Chemicals Corporation | FRL0000171 | NAPHTHOFLUORESCEIN 95.00% | 1MG | $416 | 2021-12-16 | Buy |
| American Custom Chemicals Corporation | FRL0000171 | NAPHTHOFLUORESCEIN 95.00% | 5MG | $426 | 2021-12-16 | Buy |
| American Custom Chemicals Corporation | FRL0000171 | NAPHTHOFLUORESCEIN 95.00% | 10MG | $452 | 2021-12-16 | Buy |
| Arctom | HY-124473 | Naphthofluorescein 99.02% | 50mg | $75 | 2026-05-26 | Buy |
| Arctom | HY-124473 | Naphthofluorescein 99.02% | 100mg | $97 | 2026-05-26 | Buy |
| Arctom | HY-124473 | Naphthofluorescein 99.02% | 25mg | $54 | 2026-05-26 | Buy |
| Arctom | HY-124473 | Naphthofluorescein 99.02% | 5mg | $24 | 2026-05-26 | Buy |
| Arctom | HY-124473 | Naphthofluorescein 99.02% | 10mg | $34 | 2026-05-26 | Buy |
Properties
Melting point :189 °C (dec.)(lit.)
Boiling point :755.5±60.0 °C(Predicted)
Density :1.58±0.1 g/cm3(Predicted)
storage temp. :Store at -20°C
solubility :DMF: soluble
form :A crystalline solid
pka :8.82±0.20(Predicted)
color :Purple to purplish red
BRN :61335
InChI :1S/C28H16O5/c29-17-7-9-19-15(13-17)5-11-23-25(19)32-26-20-10-8-18(30)14-16(20)6-12-24(26)28(23)22-4-2-1-3-21(22)27(31)33-28/h1-14,29-30H
InChIKey :IXQIUDNVFVTQLJ-UHFFFAOYSA-N
SMILES :Oc1ccc2c3Oc4c(ccc5cc(O)ccc45)C6(OC(=O)c7ccccc67)c3ccc2c1
EPA Substance Registry System :Spiro[7H-dibenzo[c,h]xanthene-7,1'(3'H)-isobenzofuran]-3'-one, 3,11-dihydroxy- (61419-02-1)
Boiling point :755.5±60.0 °C(Predicted)
Density :1.58±0.1 g/cm3(Predicted)
storage temp. :Store at -20°C
solubility :DMF: soluble
form :A crystalline solid
pka :8.82±0.20(Predicted)
color :Purple to purplish red
BRN :61335
InChI :1S/C28H16O5/c29-17-7-9-19-15(13-17)5-11-23-25(19)32-26-20-10-8-18(30)14-16(20)6-12-24(26)28(23)22-4-2-1-3-21(22)27(31)33-28/h1-14,29-30H
InChIKey :IXQIUDNVFVTQLJ-UHFFFAOYSA-N
SMILES :Oc1ccc2c3Oc4c(ccc5cc(O)ccc45)C6(OC(=O)c7ccccc67)c3ccc2c1
EPA Substance Registry System :Spiro[7H-dibenzo[c,h]xanthene-7,1'(3'H)-isobenzofuran]-3'-one, 3,11-dihydroxy- (61419-02-1)
Safety Information
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Description
Furin is a proprotein convertase, converting precursor proteins to functional proteins within the Golgi/trans-Golgi secretory pathway. Naphthofluorescein is a cell-permeable inhibitor of furin (IC50 = 12 μM). It inhibits furin-mediated cleavage of the pro-form of membrane type-1 matrix metalloproteinase MT1-MMP, resulting in decreased levels of active MT1-MMP. This, in turn, suppresses MMP-2 activation and reduces cell motility in CHO cells expressing proMT1-MMP. Napthofluorescein significantly inhibits the invasion of Matrigel by the human fibrosarcoma cell line, HT1080. The effects of this furin inhibitor on other furin-mediated processes, in vivo or in vitro, remain to be determined.Related product price
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