NEUROMEDIN U-25 (HUMAN)
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- $98 - $600
- Product name: NEUROMEDIN U-25 (HUMAN)
- CAS: 312306-89-1
- MF: C141H203N41O38
- MW: 3080.37
- EINECS:
- MDL Number:MFCD03457694
- Synonyms:NEUROMEDIN U-25 (HUMAN);NMU-25 (HUMAN);GLY-ASN-HIS-TRP-ALA-VAL-GLY-HIS-LEU-MET-NH2: GNHWAVGHLM-NH2;PHE-ARG-VAL-ASP-GLU-GLU-PHE-GLN-SER-PRO-PHE-ALA-SER-GLN-SER-ARG-GLY-TYR-PHE-LEU-PHE-ARG-PRO-ARG-ASN-NH2;NeuroMedin U-25 (huMan) NMU-25 (huMan);H-PHE-ARG-VAL-ASP-GLU-GLU-PHE-GLN-SER-PRO-PHE-ALA-SER-GLN-SER-ARG-GLY-TYR-PHE-LEU-PHE-ARG-PRO-ARG-ASN-NH2;Neuromedin U-25 (porcine) trifluoroacetate salt;L-Aspartamide, L-phenylalanyl-L-arginyl-L-valyl-L-α-aspartyl-L-α-glutamyl-L-α-glutamyl-L-phenylalanyl-L-glutaminyl-L-seryl-L-prolyl-L-phenylalanyl-L-alanyl-L-seryl-L-glutaminyl-L-seryl-L-arginylglycyl-L-tyrosyl-L-phenylalanyl-L-leucyl-L-phenylalanyl-L-arginyl-L-prolyl-L-arginyl-
4 prices
Selected condition：
Brand
- Adipogen Life Sciences
- Cayman Chemical
Package
- 500μg
- 1mg
- 5mg
- ManufacturerAdipogen Life Sciences
- Product numberAG-CP3-0031-M005
- Product descriptionNeuromedinU-25(human) ≥98%(HPLC)
- Packaging5mg
- Price$600
- Updated2021-12-16
- Buy
- ManufacturerCayman Chemical
- Product number17617
- Product descriptionNeuromedin U-25 (human)
- Packaging500μg
- Price$98
- Updated2021-12-16
- Buy
- ManufacturerCayman Chemical
- Product number17617
- Product descriptionNeuromedin U-25 (human)
- Packaging1mg
- Price$147
- Updated2021-12-16
- Buy
- ManufacturerCayman Chemical
- Product number17617
- Product descriptionNeuromedin U-25 (human)
- Packaging5mg
- Price$588
- Updated2021-12-16
- Buy
| Manufacturer | Product number | Product description | Packaging | Price | Updated | Buy |
|---|---|---|---|---|---|---|
| Adipogen Life Sciences | AG-CP3-0031-M005 | NeuromedinU-25(human) ≥98%(HPLC) | 5mg | $600 | 2021-12-16 | Buy |
| Cayman Chemical | 17617 | Neuromedin U-25 (human) | 500μg | $98 | 2021-12-16 | Buy |
| Cayman Chemical | 17617 | Neuromedin U-25 (human) | 1mg | $147 | 2021-12-16 | Buy |
| Cayman Chemical | 17617 | Neuromedin U-25 (human) | 5mg | $588 | 2021-12-16 | Buy |
Properties
storage temp. :−20°C
form :lyophilized powder
Sequence :Phe-Arg-Val-Asp-Glu-Glu-Phe-Gln-Ser-Pro-Phe-Ala-Ser-Gln-Ser-Arg-Gly-Tyr-Phe-Leu-Phe-Arg-Pro-Arg-Asn-NH2
form :lyophilized powder
Sequence :Phe-Arg-Val-Asp-Glu-Glu-Phe-Gln-Ser-Pro-Phe-Ala-Ser-Gln-Ser-Arg-Gly-Tyr-Phe-Leu-Phe-Arg-Pro-Arg-Asn-NH2
Safety Information
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Description
Neuromedin U (NMU) is a neuropeptide first demonstrated to drive smooth muscle contraction. Translated as a 174 amino acid propeptide, NMU is cleaved to different lengths in different animals. It has diverse receptor-mediated roles in vivo, as it regulates feeding, vasoconstriction, nociception, and bone remodeling and contributes to obesity, cancer and septic shock. NMU-25 is the active form of NMU in humans. It binds with high affinity to receptors on human left ventricle and coronary artery (KDs = 0.26 and 0.11 nM, respectively), eliciting endothelium-independent vasoconstriction. NMU-25 also suppresses glucose-stimulated insulin secretion in human islets, and this effect is lost in NMU R165W mutants, resulting in early-onset obesity.Related product price
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