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ChemicalBook >> CAS DataBase List >> N/aa

N/aa

N/aa price.
  • $44 - $3500
  • Product name: N/aa
  • CAS: 1311136-84-1
  • MF: C18H19N3O4
  • MW: 341.36
  • EINECS:-0
  • MDL Number:MFCD32062776
  • Synonyms:2,4-Imidazolidinedione, 5-ethyl-3-[6-(3-methoxy-4-methylphenoxy)-3-pyridinyl]-, (5R)-;(5R)-5-Ethyl-3-[6-(3-methoxy-4-methylphenoxy)-3-pyridinyl]-2,4-imidazolidinedione;Kv3.1b,corticolimbic circuits,inhibit,AUT 1,AUT1,dysfunction,Potassium Channel,recombinant human Kv3 channels,human recombinant,KcsA,schizophrenia,Inhibitor,AUT-1,Kv3.2a;(R)-5-Ethyl-3-(6-(3-methoxy-4-methylphenoxy)pyridin-3-yl)imidazolidine-2,4-dione;(5R)-5-ethyl-3-[6-(3-methoxy-4-methylphenoxy)pyridin-3-yl]imidazolidine-2,4-dione;(R)-5-Ethyl-3-(6-(3-methoxy-4-methylphenoxy)pyridin-3-yl)imidazolidine-2,4-dione , AUT1;AUT1, 10 mM in DMSO
14 prices
Selected condition:
Brand
  • AK Scientific
  • American Custom Chemicals Corporation
  • Cayman Chemical
  • ChemScene
  • DC Chemicals
  • TRC
Package
  • 5MG
  • 10mg
  • 50mg
  • 100mg
  • 500mg
  • 1g
  • ManufacturerAK Scientific
  • Product number4260DK
  • Product description(5R)-5-Ethyl-3-[6-(3-methoxy-4-methylphenoxy)pyridin-3-yl]imidazolidine-2,4-dione
  • Packaging10mg
  • Price$147
  • Updated2021-12-16
  • Buy
  • ManufacturerAK Scientific
  • Product number4260DK
  • Product description(5R)-5-Ethyl-3-[6-(3-methoxy-4-methylphenoxy)pyridin-3-yl]imidazolidine-2,4-dione
  • Packaging50mg
  • Price$313
  • Updated2021-12-16
  • Buy
  • ManufacturerAmerican Custom Chemicals Corporation
  • Product numberBRS0009224
  • Product descriptionAUT1 95.00%
  • Packaging5MG
  • Price$457.96
  • Updated2021-12-16
  • Buy
  • ManufacturerCayman Chemical
  • Product number28599
  • Product descriptionAUT1
  • Packaging10mg
  • Price$44
  • Updated2024-03-01
  • Buy
  • ManufacturerCayman Chemical
  • Product number28599
  • Product descriptionAUT1
  • Packaging50mg
  • Price$193
  • Updated2024-03-01
  • Buy
  • ManufacturerCayman Chemical
  • Product number28599
  • Product descriptionAUT1
  • Packaging100mg
  • Price$341
  • Updated2024-03-01
  • Buy
  • ManufacturerChemScene
  • Product numberCS-0066686
  • Product descriptionAUT1 99.95%
  • Packaging5mg
  • Price$450
  • Updated2021-12-16
  • Buy
  • ManufacturerChemScene
  • Product numberCS-0066686
  • Product descriptionAUT1 99.95%
  • Packaging10mg
  • Price$750
  • Updated2021-12-16
  • Buy
  • ManufacturerChemScene
  • Product numberCS-0066686
  • Product descriptionAUT1 99.95%
  • Packaging50mg
  • Price$2250
  • Updated2021-12-16
  • Buy
  • ManufacturerChemScene
  • Product numberCS-0066686
  • Product descriptionAUT1 99.95%
  • Packaging100mg
  • Price$3500
  • Updated2021-12-16
  • Buy
  • ManufacturerDC Chemicals
  • Product numberDC11999
  • Product descriptionAUT-1 >98%
  • Packaging100mg
  • Price$650
  • Updated2021-12-16
  • Buy
  • ManufacturerDC Chemicals
  • Product numberDC11999
  • Product descriptionAUT-1 >98%
  • Packaging1g
  • Price$2300
  • Updated2021-12-16
  • Buy
  • ManufacturerTRC
  • Product numberE678890
  • Product description(5R)-5-Ethyl-3-[6-(3-methoxy-4-methylphenoxy)-3-pyridinyl]-2,4-imidazolidinedione
  • Packaging50mg
  • Price$185
  • Updated2021-12-16
  • Buy
  • ManufacturerTRC
  • Product numberE678890
  • Product description(5R)-5-Ethyl-3-[6-(3-methoxy-4-methylphenoxy)-3-pyridinyl]-2,4-imidazolidinedione
  • Packaging500mg
  • Price$1470
  • Updated2021-12-16
  • Buy
Manufacturer Product number Product description Packaging Price Updated Buy
AK Scientific 4260DK (5R)-5-Ethyl-3-[6-(3-methoxy-4-methylphenoxy)pyridin-3-yl]imidazolidine-2,4-dione 10mg $147 2021-12-16 Buy
AK Scientific 4260DK (5R)-5-Ethyl-3-[6-(3-methoxy-4-methylphenoxy)pyridin-3-yl]imidazolidine-2,4-dione 50mg $313 2021-12-16 Buy
American Custom Chemicals Corporation BRS0009224 AUT1 95.00% 5MG $457.96 2021-12-16 Buy
Cayman Chemical 28599 AUT1 10mg $44 2024-03-01 Buy
Cayman Chemical 28599 AUT1 50mg $193 2024-03-01 Buy
Cayman Chemical 28599 AUT1 100mg $341 2024-03-01 Buy
ChemScene CS-0066686 AUT1 99.95% 5mg $450 2021-12-16 Buy
ChemScene CS-0066686 AUT1 99.95% 10mg $750 2021-12-16 Buy
ChemScene CS-0066686 AUT1 99.95% 50mg $2250 2021-12-16 Buy
ChemScene CS-0066686 AUT1 99.95% 100mg $3500 2021-12-16 Buy
DC Chemicals DC11999 AUT-1 >98% 100mg $650 2021-12-16 Buy
DC Chemicals DC11999 AUT-1 >98% 1g $2300 2021-12-16 Buy
TRC E678890 (5R)-5-Ethyl-3-[6-(3-methoxy-4-methylphenoxy)-3-pyridinyl]-2,4-imidazolidinedione 50mg $185 2021-12-16 Buy
TRC E678890 (5R)-5-Ethyl-3-[6-(3-methoxy-4-methylphenoxy)-3-pyridinyl]-2,4-imidazolidinedione 500mg $1470 2021-12-16 Buy

Properties

storage temp. :Store at -20°C
solubility :DMSO:PBS (pH 7.2) (1:4):0.2(Max Conc. mg/mL);0.59(Max Conc. mM)
DMF:30.0(Max Conc. mg/mL);87.88(Max Conc. mM)
Ethanol:5.0(Max Conc. mg/mL);14.65(Max Conc. mM) form :A crystalline solid
color :White to off-white

Safety Information

Symbol(GHS):
Signal word:
Hazard statements:
Code Hazard statements Hazard class Category Signal word Pictogram P-Codes
Precautionary statements:

Description

AUT1 is a positive modulator of the voltage-gated potassium channel subtypes Kv3.1b, Kv3.2a, and Kv3.3 (EC50s = 4.7, 4.9, and 31.6 μM, respectively, in a patch-clamp assay). It is selective for Kv3.1b, Kv3.2a, and Kv3.3 over Kv1.5 and Kv7.1/minK channels but also inhibits the serotonin (5-HT) transporter, 5-HT3 receptor, and α1 subunit-containing nicotinic acetylcholine receptor (nAChR) in a panel of 26 ion channels, receptors, and transporters. AUT1 increases tetraethylammonium-induced decreases in the firing frequency and amplitude of action potentials in mouse somatosensory cortex slices when used at concentrations of 1 and 10 μM.