PRL-3 INHIBITOR I
|
- $27 - $1800
- Product name: PRL-3 INHIBITOR I
- CAS: 893449-38-2
- MF: C17H11Br2NO2S2
- MW: 485.21
- EINECS:
- MDL Number:MFCD11045303
- Synonyms:PRL-3 INHIBITOR I;Phosphatase of regenerating liver-3, Inhibitor I, 5-[[5-bromo-2-[(2-bromophenyl)methoxy]phenyl]methylene]-2-thioxo-4-thiazolidinone;5-[[5-bromo-2-[(2-bromophenyl)methoxy]phenyl]methylene]-2-thioxo-4-thiazolidinone;Phosphatase of regenerating liver-3, Inhibitor I;PRL-3 Inhibitor;PRL-3 Inhibitor - CAS 893449-38-2 - Calbiochem;5-(5-Bromo-2-((2-bromobenzyl)oxy)benzylidene)-2-thioxothiazolidin-4-one;P0180
38 prices
Selected condition：
Brand
- aablocks
- ACHEMBLOCK
- American Custom Chemicals Corporation
- ApexBio Technology
- AvaChem
- Axon Medchem
- Cayman Chemical
- ChemScene
- DC Chemicals
- Matrix Scientific
- Sigma-Aldrich
- TRC
- Usbiological
Package
- 1mg
- 5MG
- 10mg
- 25mg
- 50.00mg
- 50mg
- 100.00mg
- 100mg
- 250MG
- 250.00mg
- 1G
- Manufactureraablocks
- Product numberAA0086LF
- Product descriptionPRL-3 Inhibitor
- Packaging100mg
- Price$164
- Updated2026-05-28
- Buy
- Manufactureraablocks
- Product numberAA0086LF
- Product descriptionPRL-3 Inhibitor 98%
- Packaging50mg
- Price$87
- Updated2026-05-28
- Buy
- Manufactureraablocks
- Product numberAA0086LF
- Product descriptionPRL-3 Inhibitor
- Packaging25mg
- Price$75
- Updated2026-05-28
- Buy
- Manufactureraablocks
- Product numberAA0086LF
- Product descriptionPRL-3 Inhibitor
- Packaging10mg
- Price$45
- Updated2026-05-28
- Buy
- Manufactureraablocks
- Product numberAA0086LF
- Product descriptionPRL-3 Inhibitor ≥95%
- Packaging1mg
- Price$36
- Updated2026-05-28
- Buy
- ManufacturerACHEMBLOCK
- Product numberV153271
- Product descriptionPRL-3 Inhibitor I 98%
- Packaging250MG
- Price$335
- Updated2026-05-27
- Buy
- ManufacturerACHEMBLOCK
- Product numberV153271
- Product descriptionPRL-3 Inhibitor I 98%
- Packaging100MG
- Price$160
- Updated2026-05-27
- Buy
- ManufacturerACHEMBLOCK
- Product numberV153271
- Product descriptionPRL-3 Inhibitor I 98%
- Packaging1G
- Price$1005
- Updated2026-05-27
- Buy
- ManufacturerAmerican Custom Chemicals Corporation
- Product numberINB0000809
- Product descriptionPRL-3 INHIBITOR I 95.00%
- Packaging5MG
- Price$663.07
- Updated2021-12-16
- Buy
- ManufacturerApexBio Technology
- Product numberC3996
- Product descriptionPRL-3 Inhibitor
- Packaging25mg
- Price$291
- Updated2026-05-06
- Buy
- ManufacturerApexBio Technology
- Product numberC3996
- Product descriptionPRL-3 Inhibitor
- Packaging5mg
- Price$87
- Updated2026-05-06
- Buy
- ManufacturerApexBio Technology
- Product numberC3996
- Product descriptionPRL-3 Inhibitor
- Packaging10mg
- Price$145
- Updated2026-05-06
- Buy
- ManufacturerAvaChem
- Product number6631
- Product descriptionP0108 98%
- Packaging25mg
- Price$240
- Updated2026-05-22
- Buy
- ManufacturerAvaChem
- Product number6631
- Product descriptionP0108 98%
- Packaging5mg
- Price$60
- Updated2026-05-22
- Buy
- ManufacturerAxon Medchem
- Product numberAxon3436
- Product descriptionPRL-3 inhibitor
- Packaging10mg
- Price$99
- Updated2026-05-19
- Buy
- ManufacturerAxon Medchem
- Product numberAxon3436
- Product descriptionPRL-3 inhibitor
- Packaging50mg
- Price$330
- Updated2026-05-19
- Buy
| Manufacturer | Product number | Product description | Packaging | Price | Updated | Buy |
|---|---|---|---|---|---|---|
| aablocks | AA0086LF | PRL-3 Inhibitor | 100mg | $164 | 2026-05-28 | Buy |
| aablocks | AA0086LF | PRL-3 Inhibitor 98% | 50mg | $87 | 2026-05-28 | Buy |
| aablocks | AA0086LF | PRL-3 Inhibitor | 25mg | $75 | 2026-05-28 | Buy |
| aablocks | AA0086LF | PRL-3 Inhibitor | 10mg | $45 | 2026-05-28 | Buy |
| aablocks | AA0086LF | PRL-3 Inhibitor ≥95% | 1mg | $36 | 2026-05-28 | Buy |
| ACHEMBLOCK | V153271 | PRL-3 Inhibitor I 98% | 250MG | $335 | 2026-05-27 | Buy |
| ACHEMBLOCK | V153271 | PRL-3 Inhibitor I 98% | 100MG | $160 | 2026-05-27 | Buy |
| ACHEMBLOCK | V153271 | PRL-3 Inhibitor I 98% | 1G | $1005 | 2026-05-27 | Buy |
| American Custom Chemicals Corporation | INB0000809 | PRL-3 INHIBITOR I 95.00% | 5MG | $663.07 | 2021-12-16 | Buy |
| ApexBio Technology | C3996 | PRL-3 Inhibitor | 25mg | $291 | 2026-05-06 | Buy |
| ApexBio Technology | C3996 | PRL-3 Inhibitor | 5mg | $87 | 2026-05-06 | Buy |
| ApexBio Technology | C3996 | PRL-3 Inhibitor | 10mg | $145 | 2026-05-06 | Buy |
| AvaChem | 6631 | P0108 98% | 25mg | $240 | 2026-05-22 | Buy |
| AvaChem | 6631 | P0108 98% | 5mg | $60 | 2026-05-22 | Buy |
| Axon Medchem | Axon3436 | PRL-3 inhibitor | 10mg | $99 | 2026-05-19 | Buy |
| Axon Medchem | Axon3436 | PRL-3 inhibitor | 50mg | $330 | 2026-05-19 | Buy |
Properties
Density :1.85±0.1 g/cm3(Predicted)
storage temp. :−20°C
solubility :DMSO: >10mg/mL
form :Yellow solid
pka :7.11±0.50(Predicted)
color :yellow
Stability :Stable for 1 year from date of purchase as supplied. Solutions in DMSO may be stored at -20°C for up to 2 months.
InChI :1S/C17H11Br2NO2S2/c18-12-5-6-14(22-9-10-3-1-2-4-13(10)19)11(7-12)8-15-16(21)20-17(23)24-15/h1-8H,9H2,(H,20,21,23)/b15-8+
InChIKey :HXNBAOLVPAWYLT-OVCLIPMQSA-N
SMILES :Brc1ccc(OCc2ccccc2Br)c(c1)\C=C3\SC(=S)NC3=O
storage temp. :−20°C
solubility :DMSO: >10mg/mL
form :Yellow solid
pka :7.11±0.50(Predicted)
color :yellow
Stability :Stable for 1 year from date of purchase as supplied. Solutions in DMSO may be stored at -20°C for up to 2 months.
InChI :1S/C17H11Br2NO2S2/c18-12-5-6-14(22-9-10-3-1-2-4-13(10)19)11(7-12)8-15-16(21)20-17(23)24-15/h1-8H,9H2,(H,20,21,23)/b15-8+
InChIKey :HXNBAOLVPAWYLT-OVCLIPMQSA-N
SMILES :Brc1ccc(OCc2ccccc2Br)c(c1)\C=C3\SC(=S)NC3=O
Safety Information
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| Signal word: | Warning | |||||||||||||||||||||||||||||||||||
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Description
Phosphatase of regenerating liver 3 (PRL-3; also known as PTP4A3) plays critical roles in cell proliferation, motility, and invasion, and thus contributes to cancer metastasis. PRL-3 inhibitor is a cell-permeable benzylidene rhodamine that inhibits PRL-3 (IC50 = 900 nM for human PRL-3 in vitro), with minimal activity against other phosphatases. It reduces the invasion of mouse melanoma B16F10 cells in a cell-based assay. PRL-3 inhibitor has been used to elucidate the actions of this enzyme, demonstrating that it dephosphorylates Tyr783 on integrin β1 and modulates VEGF-mediated endothelial cell migration. It dose-dependently inhibits the growth and triggers apoptosis in cancer cell lines.Related product price
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