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ChemicalBook >> CAS DataBase List >> Purvalanol a

Purvalanol a

Purvalanol a price.
  • $10 - $1800
  • Product name: Purvalanol a
  • CAS: 212844-53-6
  • MF: C19H25ClN6O
  • MW: 388.89
  • EINECS:
  • MDL Number:MFCD02179211
  • Synonyms:NG-60;6-(3-CHLOROANILINO)-2(1R)-ISOPROPYL-2-HYDROXYETHYLAMINO-9-ISOPROPYLPURINE;(2R)-2-[[6-[(3-CHLOROPHENYL)AMINO]-9-(1-METHYLETHYL)-9H-PURIN-2-YL]AMINO]-3-METHYL-1-BUTANOL;2-(1R-ISOPROPOYL-2-HYDROXYETHYLAMINO)-6-(3-CHLOROANILINO)-9-ISOPROPYLPURINE;2-(1R-ISOPROPYL-2-HYDROXYETHYLAMINO)-6-(3-CHLOROANILINO)-9-ISOPROPYL-PURINE;CH61386;2R)-2-[[6-[(3-Chlorophenyl)amino]-9-(1-methylethyl)-9H-purin-2-yl]amino]-3-methyl-1-butanolCDKinhibitor.;PurvalanolA,CDKinhibitor
Price74 Properties Safety Information Description
74 prices
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Brand
  • aablocks
  • ACHEMBLOCK
  • Adipogen Life Sciences
  • AK Scientific
  • Ambeed
  • American Custom Chemicals Corporation
  • ApexBio Technology
  • Apolloscientific
  • Arctom
  • AvaChem
  • Cayman Chemical
  • Chemenu
  • ChemScene
  • Crysdot
  • DC Chemicals
  • Matrix Scientific
  • Sigma-Aldrich
  • Tocris
  • TRC
  • Usbiological
Package
  • 10.00mg
  • 10mM*1mLinDMSO(Solution)
  • 10mM(in 1mL DMSO)
  • 25.00mg
  • 10mM*1mLinDMSO(Solid+Solvent)
  • 50
  • 50.00mg
  • 200mg
  • 10
  • 500mg
  • 1mg
  • 2mg
  • 5mg
  • 10mg
  • 25mg
  • 50mg
  • 100mg
  • 250mg
  • 1G
  • 10mM(in1mLDMSO)
  • Manufactureraablocks
  • Product numberAA007QT2
  • Product description(2R)-2-[[6-[(3-Chlorophenyl)amino]-9-(1-methylethyl)-9H-purin-2-yl]amino]-3-methyl-1-butanol ≥98%
  • Packaging1mg
  • Price$10
  • Updated2026-05-28
  • Buy
  • Manufactureraablocks
  • Product numberAA007QT2
  • Product description(2R)-2-[[6-[(3-Chlorophenyl)amino]-9-(1-methylethyl)-9H-purin-2-yl]amino]-3-methyl-1-butanol ≥98%
  • Packaging5mg
  • Price$16
  • Updated2026-05-28
  • Buy
  • Manufactureraablocks
  • Product numberAA007QT2
  • Product description(2R)-2-[[6-[(3-Chlorophenyl)amino]-9-(1-methylethyl)-9H-purin-2-yl]amino]-3-methyl-1-butanol ≥98%
  • Packaging10mg
  • Price$28
  • Updated2026-05-28
  • Buy
  • Manufactureraablocks
  • Product numberAA007QT2
  • Product description(2R)-2-[[6-[(3-Chlorophenyl)amino]-9-(1-methylethyl)-9H-purin-2-yl]amino]-3-methyl-1-butanol 98%
  • Packaging25mg
  • Price$53
  • Updated2026-05-28
  • Buy
  • Manufactureraablocks
  • Product numberAA007QT2
  • Product description(2R)-2-[[6-[(3-Chlorophenyl)amino]-9-(1-methylethyl)-9H-purin-2-yl]amino]-3-methyl-1-butanol 98%
  • Packaging50mg
  • Price$86
  • Updated2026-05-28
  • Buy
  • Manufactureraablocks
  • Product numberAA007QT2
  • Product description(2R)-2-[[6-[(3-Chlorophenyl)amino]-9-(1-methylethyl)-9H-purin-2-yl]amino]-3-methyl-1-butanol 98%
  • Packaging100mg
  • Price$133
  • Updated2026-05-28
  • Buy
  • Manufactureraablocks
  • Product numberAA007QT2
  • Product description(2R)-2-[[6-[(3-Chlorophenyl)amino]-9-(1-methylethyl)-9H-purin-2-yl]amino]-3-methyl-1-butanol 98%
  • Packaging250mg
  • Price$227
  • Updated2026-05-28
  • Buy
  • ManufacturerACHEMBLOCK
  • Product numberO33856
  • Product descriptionPurvalanol A 98%
  • Packaging100MG
  • Price$190
  • Updated2026-05-27
  • Buy
  • ManufacturerACHEMBLOCK
  • Product numberO33856
  • Product descriptionPurvalanol A 98%
  • Packaging250MG
  • Price$375
  • Updated2026-05-27
  • Buy
  • ManufacturerACHEMBLOCK
  • Product numberO33856
  • Product descriptionPurvalanol A 98%
  • Packaging1G
  • Price$790
  • Updated2026-05-27
  • Buy
  • ManufacturerAdipogen Life Sciences
  • Product numberAG-CR1-2903-M025
  • Product descriptionPurvalanol A ≥98%(HPLC)
  • Packaging25mg
  • Price$240
  • Updated2026-05-06
  • Buy
  • ManufacturerAdipogen Life Sciences
  • Product numberAG-CR1-2903-M005
  • Product descriptionPurvalanol A ≥98%(HPLC)
  • Packaging5mg
  • Price$85
  • Updated2026-05-06
  • Buy
  • ManufacturerAdipogen Life Sciences
  • Product numberAG-CR1-2903-M001
  • Product descriptionPurvalanol A ≥98%(HPLC)
  • Packaging1mg
  • Price$40
  • Updated2026-05-06
  • Buy
  • ManufacturerAK Scientific
  • Product number3983AH
  • Product descriptionPurvalanol A
  • Packaging5mg
  • Price$107
  • Updated2021-12-16
  • Buy
  • ManufacturerAmbeed
  • Product numberA106338
  • Product descriptionPurvalanol A 98+%
  • Packaging50mg
  • Price$112
  • Updated2021-12-16
  • Buy
  • ManufacturerAmbeed
  • Product numberA106338
  • Product descriptionPurvalanol A 98+%
  • Packaging5mg
  • Price$28
  • Updated2021-12-16
  • Buy
Manufacturer Product number Product description Packaging Price Updated Buy
aablocks AA007QT2 (2R)-2-[[6-[(3-Chlorophenyl)amino]-9-(1-methylethyl)-9H-purin-2-yl]amino]-3-methyl-1-butanol ≥98% 1mg $10 2026-05-28 Buy
aablocks AA007QT2 (2R)-2-[[6-[(3-Chlorophenyl)amino]-9-(1-methylethyl)-9H-purin-2-yl]amino]-3-methyl-1-butanol ≥98% 5mg $16 2026-05-28 Buy
aablocks AA007QT2 (2R)-2-[[6-[(3-Chlorophenyl)amino]-9-(1-methylethyl)-9H-purin-2-yl]amino]-3-methyl-1-butanol ≥98% 10mg $28 2026-05-28 Buy
aablocks AA007QT2 (2R)-2-[[6-[(3-Chlorophenyl)amino]-9-(1-methylethyl)-9H-purin-2-yl]amino]-3-methyl-1-butanol 98% 25mg $53 2026-05-28 Buy
aablocks AA007QT2 (2R)-2-[[6-[(3-Chlorophenyl)amino]-9-(1-methylethyl)-9H-purin-2-yl]amino]-3-methyl-1-butanol 98% 50mg $86 2026-05-28 Buy
aablocks AA007QT2 (2R)-2-[[6-[(3-Chlorophenyl)amino]-9-(1-methylethyl)-9H-purin-2-yl]amino]-3-methyl-1-butanol 98% 100mg $133 2026-05-28 Buy
aablocks AA007QT2 (2R)-2-[[6-[(3-Chlorophenyl)amino]-9-(1-methylethyl)-9H-purin-2-yl]amino]-3-methyl-1-butanol 98% 250mg $227 2026-05-28 Buy
ACHEMBLOCK O33856 Purvalanol A 98% 100MG $190 2026-05-27 Buy
ACHEMBLOCK O33856 Purvalanol A 98% 250MG $375 2026-05-27 Buy
ACHEMBLOCK O33856 Purvalanol A 98% 1G $790 2026-05-27 Buy
Adipogen Life Sciences AG-CR1-2903-M025 Purvalanol A ≥98%(HPLC) 25mg $240 2026-05-06 Buy
Adipogen Life Sciences AG-CR1-2903-M005 Purvalanol A ≥98%(HPLC) 5mg $85 2026-05-06 Buy
Adipogen Life Sciences AG-CR1-2903-M001 Purvalanol A ≥98%(HPLC) 1mg $40 2026-05-06 Buy
AK Scientific 3983AH Purvalanol A 5mg $107 2021-12-16 Buy
Ambeed A106338 Purvalanol A 98+% 50mg $112 2021-12-16 Buy
Ambeed A106338 Purvalanol A 98+% 5mg $28 2021-12-16 Buy
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Properties

Boiling point :590.5±60.0 °C(Predicted)
Density :1.33±0.1 g/cm3(Predicted)
storage temp. :Keep in dark place,Inert atmosphere,Store in freezer, under -20°C
solubility :methylene chloride: 50 mg/mL, clear, colorless
form :powder
pka :14.51±0.10(Predicted)
color :off-white
Stability :Stable for 1 year from date of purchase as supplied. Solutions in DMSO may be stored at -20°C for up to 2 months.
InChI :1S/C19H25ClN6O/c1-11(2)15(9-27)23-19-24-17(22-14-7-5-6-13(20)8-14)16-18(25-19)26(10-21-16)12(3)4/h5-8,10-12,15,27H,9H2,1-4H3,(H2,22,23,24,25)/t15-/m0/s1
InChIKey :PMXCMJLOPOFPBT-HNNXBMFYSA-N
SMILES :Clc1cc(ccc1)Nc2nc(nc3[n](cnc32)C(C)C)N[C@@H](CO)C(C)C

Safety Information

Symbol(GHS): Exclamation Mark (GHS07)
Signal word: Warning
Hazard statements:
Code Hazard statements Hazard class Category Signal word Pictogram P-Codes
H315 Causes skin irritation Skin corrosion/irritation Category 2 Warning P264, P280, P302+P352, P321,P332+P313, P362
H319 Causes serious eye irritation Serious eye damage/eye irritation Category 2A Warning P264, P280, P305+P351+P338,P337+P313P
H335 May cause respiratory irritation Specific target organ toxicity, single exposure;Respiratory tract irritation Category 3 Warning
Precautionary statements:
P261 Avoid breathing dust/fume/gas/mist/vapours/spray.
P271 Use only outdoors or in a well-ventilated area.
P280 Wear protective gloves/protective clothing/eye protection/face protection.

Description

Purvalanol A is a potent, cell-permeable, and selective inhibitor of cyclin-dependent kinases (CDKs) with IC50 values of 4, 70, 35, 850, and 75 nM for cdc2/cyclin B, Cdk2/cyclin A, Cdk2/cyclin E, Cdk4/cyclin D1 and Cdk5-p35, respectively. Purvalanol A reversibly arrests synchronized cells in the G1 and G2 phase of the cell cycle, inhibiting both cell proliferation and cell death. At 10 μM, purvalanol A potently suppresses the anchorage-independent growth of c-Src-transformed cells as well as HT-29 and SW48 human colon cancer cells.

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Suppliers and manufacturers

Shanghai Boyle Chemical Co., Ltd. 3B Pharmachem (Wuhan) International Co.,Ltd. Ascent Scientific Haoyuan Chemexpress Co., Ltd. MedChemexpress LLC Bide Pharmatech Ltd. AdooQ Bioscience CHINA Shanghai JiYi Biotechnology Co. Ltd. Shanghai Lollane Biological Technology Co.,Ltd. Shanghaizehan biopharma technology co., Ltd.