Phthalazinone pyrazole
|
- $50 - $1900
- Product name: Phthalazinone pyrazole
- CAS: 880487-62-7
- MF: C18H15N5O
- MW: 317.34
- EINECS:
- MDL Number:MFCD28399120
- Synonyms:Phthalazinone pyrazole;Phthalazinone pyrazole Exclusive;4-[(5-methyl-1H-pyrazol-3-yl)amino]-2-phenylphthalazin-1-one;1(2H)-Phthalazinone, 4-[(5-methyl-1H-pyrazol-3-yl)amino]-2-phenyl-;4-[(5-Methyl-1H-pyrazol-3-yl)amino]-2-phenyl-2H-phthalazin-1-one;Phthalazinone pyrazole,inhibit,human embryonic stem cells,Aurora Kinase,hepatocyte-like cell,Inhibitor,HLCs,Aurora-A kinase,EMT,apoptosis,tumor growth,oral,epithelial-mesenchymal transition;4-[(5-methyl-1H-pyrazol-3-yl)amino]-2-phenyl-1,2-dihydrophthalazin-1-one;4-((5-Methyl-1H-pyrazol-3-yl)amino)-2-phenylphthalazin-1(2H)-one
32 prices
Selected condition:
Brand
- aablocks
- ACHEMBLOCK
- ApexBio Technology
- Arctom
- Cayman Chemical
- ChemScene
- DC Chemicals
Package
- 001
- 10mM*1mLinDMSO(Solid+Solvent)
- 250mg
- 002
- 003
- 1g
- 10mM*1mLinDMSO(Solution)
- 1mg
- 5mg
- 10mg
- 25mg
- 50mg
- 100mg
- Manufactureraablocks
- Product numberAA00GT8T
- Product description4-[(5-Methyl-1H-pyrazol-3-yl)amino]-2-phenyl-1(2H)-phthalazinone
- Packaging5mg
- Price$53
- Updated2026-05-28
- Buy
- Manufactureraablocks
- Product numberAA00GT8T
- Product description4-[(5-Methyl-1H-pyrazol-3-yl)amino]-2-phenyl-1(2H)-phthalazinone
- Packaging10mg
- Price$75
- Updated2026-05-28
- Buy
- Manufactureraablocks
- Product numberAA00GT8T
- Product descriptionPhthalazinonepyrazole ≥98%
- Packaging1mg
- Price$119
- Updated2021-12-16
- Buy
- Manufactureraablocks
- Product numberAA00GT8T
- Product description4-[(5-Methyl-1H-pyrazol-3-yl)amino]-2-phenyl-1(2H)-phthalazinone
- Packaging25mg
- Price$130
- Updated2026-05-28
- Buy
- Manufactureraablocks
- Product numberAA00GT8T
- Product description4-[(5-Methyl-1H-pyrazol-3-yl)amino]-2-phenyl-1(2H)-phthalazinone
- Packaging50mg
- Price$179
- Updated2026-05-28
- Buy
- Manufactureraablocks
- Product numberAA00GT8T
- Product description4-[(5-Methyl-1H-pyrazol-3-yl)amino]-2-phenyl-1(2H)-phthalazinone
- Packaging100mg
- Price$271
- Updated2026-05-28
- Buy
- ManufacturerACHEMBLOCK
- Product numberY227216
- Product descriptionPhthalazinone pyrazole 97.00%
- Packaging25MG
- Price$160
- Updated2026-05-27
- Buy
- ManufacturerACHEMBLOCK
- Product numberY227216
- Product descriptionPhthalazinone pyrazole 97.00%
- Packaging100MG
- Price$375
- Updated2026-05-27
- Buy
- ManufacturerApexBio Technology
- Product numberC3823
- Product descriptionPhthalazinone pyrazole
- Packaging10mg
- Price$572
- Updated2026-05-06
- Buy
- ManufacturerApexBio Technology
- Product numberC3823
- Product descriptionPhthalazinone pyrazole
- Packaging5mg
- Price$323
- Updated2026-05-06
- Buy
- ManufacturerApexBio Technology
- Product numberC3823
- Product descriptionPhthalazinone pyrazole
- Packaging1mg
- Price$67
- Updated2026-05-06
- Buy
- ManufacturerArctom
- Product numberHY-12564
- Product descriptionPhthalazinonepyrazole 98.0%
- Packaging10mg
- Price$80
- Updated2026-05-26
- Buy
- ManufacturerArctom
- Product numberHY-12564
- Product descriptionPhthalazinonepyrazole 98.0%
- Packaging10mM*1mLinDMSO(Solution)
- Price$55
- Updated2026-05-26
- Buy
- ManufacturerArctom
- Product numberHY-12564
- Product descriptionPhthalazinonepyrazole 98.0%
- Packaging5mg
- Price$50
- Updated2026-05-26
- Buy
- ManufacturerArctom
- Product numberHY-12564
- Product descriptionPhthalazinonepyrazole 98.0%
- Packaging10mM*1mLinDMSO(Solid+Solvent)
- Price$52
- Updated2026-05-26
- Buy
- ManufacturerArctom
- Product numberHY-12564
- Product descriptionPhthalazinonepyrazole 98.0%
- Packaging50mg
- Price$241
- Updated2026-05-26
- Buy
| Manufacturer | Product number | Product description | Packaging | Price | Updated | Buy |
|---|---|---|---|---|---|---|
| aablocks | AA00GT8T | 4-[(5-Methyl-1H-pyrazol-3-yl)amino]-2-phenyl-1(2H)-phthalazinone | 5mg | $53 | 2026-05-28 | Buy |
| aablocks | AA00GT8T | 4-[(5-Methyl-1H-pyrazol-3-yl)amino]-2-phenyl-1(2H)-phthalazinone | 10mg | $75 | 2026-05-28 | Buy |
| aablocks | AA00GT8T | Phthalazinonepyrazole ≥98% | 1mg | $119 | 2021-12-16 | Buy |
| aablocks | AA00GT8T | 4-[(5-Methyl-1H-pyrazol-3-yl)amino]-2-phenyl-1(2H)-phthalazinone | 25mg | $130 | 2026-05-28 | Buy |
| aablocks | AA00GT8T | 4-[(5-Methyl-1H-pyrazol-3-yl)amino]-2-phenyl-1(2H)-phthalazinone | 50mg | $179 | 2026-05-28 | Buy |
| aablocks | AA00GT8T | 4-[(5-Methyl-1H-pyrazol-3-yl)amino]-2-phenyl-1(2H)-phthalazinone | 100mg | $271 | 2026-05-28 | Buy |
| ACHEMBLOCK | Y227216 | Phthalazinone pyrazole 97.00% | 25MG | $160 | 2026-05-27 | Buy |
| ACHEMBLOCK | Y227216 | Phthalazinone pyrazole 97.00% | 100MG | $375 | 2026-05-27 | Buy |
| ApexBio Technology | C3823 | Phthalazinone pyrazole | 10mg | $572 | 2026-05-06 | Buy |
| ApexBio Technology | C3823 | Phthalazinone pyrazole | 5mg | $323 | 2026-05-06 | Buy |
| ApexBio Technology | C3823 | Phthalazinone pyrazole | 1mg | $67 | 2026-05-06 | Buy |
| Arctom | HY-12564 | Phthalazinonepyrazole 98.0% | 10mg | $80 | 2026-05-26 | Buy |
| Arctom | HY-12564 | Phthalazinonepyrazole 98.0% | 10mM*1mLinDMSO(Solution) | $55 | 2026-05-26 | Buy |
| Arctom | HY-12564 | Phthalazinonepyrazole 98.0% | 5mg | $50 | 2026-05-26 | Buy |
| Arctom | HY-12564 | Phthalazinonepyrazole 98.0% | 10mM*1mLinDMSO(Solid+Solvent) | $52 | 2026-05-26 | Buy |
| Arctom | HY-12564 | Phthalazinonepyrazole 98.0% | 50mg | $241 | 2026-05-26 | Buy |
Properties
Boiling point :557.7±52.0 °C(Predicted)
Density :1.35±0.1 g/cm3(Predicted)
storage temp. :Store at -20°C
solubility :insoluble in EtOH; insoluble in H2O; ≥7.14 mg/mL in DMSO
form :crystalline solid
pka :13.83±0.10(Predicted)
color :Brown to gray
Density :1.35±0.1 g/cm3(Predicted)
storage temp. :Store at -20°C
solubility :insoluble in EtOH; insoluble in H2O; ≥7.14 mg/mL in DMSO
form :crystalline solid
pka :13.83±0.10(Predicted)
color :Brown to gray
Safety Information
| Symbol(GHS): | ||||||||
|---|---|---|---|---|---|---|---|---|
| Signal word: | ||||||||
| Hazard statements: |
|
|||||||
| Precautionary statements: |
|
Description
Three Aurora kinases, A-C, are involved in phosphorylation events that are critical for the completion of mitosis. Aurora A, involved in centrosomal assembly and acentrosomal spindle assembly, is overexpressed in many tumors. Phthalazinone pyrazole is a potent inhibitor of Aurora A kinase (IC50 = 31 nM). It does not inhibit Aurora B kinase at doses up to 100 μM. Phthalazinone pyrazole inhibits the proliferation of HCT116, Colo205, and MCF-7 cells (IC50 = 7.8, 2.9, and 1.6 μM, respectively).Related product price
-
Phthalazinone pyrazole
$50-1900 -
PHA-680632
$18-9580.73 -
CCT129202
$48-11290
Suppliers and manufacturers
BOC Sciences
Shanghai Lollane Biological Technology Co.,Ltd.
Shanghai YuanYe Biotechnology Co., Ltd.
ShangHai Biochempartner Co.,Ltd
Shanghai Rechem science Co., Ltd.
Shanghai Chaolan Chemical Technology Center
Shanghai Yu Ben Biotechnology Co., Ltd.
Changzhou Chenhong Biotechnology Co., Ltd.
ChemeGen(Shanghai) Biotechnology Co.,Ltd.




