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ChemicalBook >> CAS DataBase List >> Phthalazinone pyrazole

Phthalazinone pyrazole

Phthalazinone pyrazole price.
  • $50 - $1900
  • Product name: Phthalazinone pyrazole
  • CAS: 880487-62-7
  • MF: C18H15N5O
  • MW: 317.34
  • EINECS:
  • MDL Number:MFCD28399120
  • Synonyms:Phthalazinone pyrazole;Phthalazinone pyrazole Exclusive;4-[(5-methyl-1H-pyrazol-3-yl)amino]-2-phenylphthalazin-1-one;1(2H)-Phthalazinone, 4-[(5-methyl-1H-pyrazol-3-yl)amino]-2-phenyl-;4-[(5-Methyl-1H-pyrazol-3-yl)amino]-2-phenyl-2H-phthalazin-1-one;Phthalazinone pyrazole,inhibit,human embryonic stem cells,Aurora Kinase,hepatocyte-like cell,Inhibitor,HLCs,Aurora-A kinase,EMT,apoptosis,tumor growth,oral,epithelial-mesenchymal transition;4-[(5-methyl-1H-pyrazol-3-yl)amino]-2-phenyl-1,2-dihydrophthalazin-1-one;4-((5-Methyl-1H-pyrazol-3-yl)amino)-2-phenylphthalazin-1(2H)-one
32 prices
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Brand
  • aablocks
  • ACHEMBLOCK
  • ApexBio Technology
  • Arctom
  • Cayman Chemical
  • ChemScene
  • DC Chemicals
Package
  • 001
  • 10mM*1mLinDMSO(Solid+Solvent)
  • 250mg
  • 002
  • 003
  • 1g
  • 10mM*1mLinDMSO(Solution)
  • 1mg
  • 5mg
  • 10mg
  • 25mg
  • 50mg
  • 100mg
  • Manufactureraablocks
  • Product numberAA00GT8T
  • Product description4-[(5-Methyl-1H-pyrazol-3-yl)amino]-2-phenyl-1(2H)-phthalazinone
  • Packaging5mg
  • Price$53
  • Updated2026-05-28
  • Buy
  • Manufactureraablocks
  • Product numberAA00GT8T
  • Product description4-[(5-Methyl-1H-pyrazol-3-yl)amino]-2-phenyl-1(2H)-phthalazinone
  • Packaging10mg
  • Price$75
  • Updated2026-05-28
  • Buy
  • Manufactureraablocks
  • Product numberAA00GT8T
  • Product descriptionPhthalazinonepyrazole ≥98%
  • Packaging1mg
  • Price$119
  • Updated2021-12-16
  • Buy
  • Manufactureraablocks
  • Product numberAA00GT8T
  • Product description4-[(5-Methyl-1H-pyrazol-3-yl)amino]-2-phenyl-1(2H)-phthalazinone
  • Packaging25mg
  • Price$130
  • Updated2026-05-28
  • Buy
  • Manufactureraablocks
  • Product numberAA00GT8T
  • Product description4-[(5-Methyl-1H-pyrazol-3-yl)amino]-2-phenyl-1(2H)-phthalazinone
  • Packaging50mg
  • Price$179
  • Updated2026-05-28
  • Buy
  • Manufactureraablocks
  • Product numberAA00GT8T
  • Product description4-[(5-Methyl-1H-pyrazol-3-yl)amino]-2-phenyl-1(2H)-phthalazinone
  • Packaging100mg
  • Price$271
  • Updated2026-05-28
  • Buy
  • ManufacturerACHEMBLOCK
  • Product numberY227216
  • Product descriptionPhthalazinone pyrazole 97.00%
  • Packaging25MG
  • Price$160
  • Updated2026-05-27
  • Buy
  • ManufacturerACHEMBLOCK
  • Product numberY227216
  • Product descriptionPhthalazinone pyrazole 97.00%
  • Packaging100MG
  • Price$375
  • Updated2026-05-27
  • Buy
  • ManufacturerApexBio Technology
  • Product numberC3823
  • Product descriptionPhthalazinone pyrazole
  • Packaging10mg
  • Price$572
  • Updated2026-05-06
  • Buy
  • ManufacturerApexBio Technology
  • Product numberC3823
  • Product descriptionPhthalazinone pyrazole
  • Packaging5mg
  • Price$323
  • Updated2026-05-06
  • Buy
  • ManufacturerApexBio Technology
  • Product numberC3823
  • Product descriptionPhthalazinone pyrazole
  • Packaging1mg
  • Price$67
  • Updated2026-05-06
  • Buy
  • ManufacturerArctom
  • Product numberHY-12564
  • Product descriptionPhthalazinonepyrazole 98.0%
  • Packaging10mg
  • Price$80
  • Updated2026-05-26
  • Buy
  • ManufacturerArctom
  • Product numberHY-12564
  • Product descriptionPhthalazinonepyrazole 98.0%
  • Packaging10mM*1mLinDMSO(Solution)
  • Price$55
  • Updated2026-05-26
  • Buy
  • ManufacturerArctom
  • Product numberHY-12564
  • Product descriptionPhthalazinonepyrazole 98.0%
  • Packaging5mg
  • Price$50
  • Updated2026-05-26
  • Buy
  • ManufacturerArctom
  • Product numberHY-12564
  • Product descriptionPhthalazinonepyrazole 98.0%
  • Packaging10mM*1mLinDMSO(Solid+Solvent)
  • Price$52
  • Updated2026-05-26
  • Buy
  • ManufacturerArctom
  • Product numberHY-12564
  • Product descriptionPhthalazinonepyrazole 98.0%
  • Packaging50mg
  • Price$241
  • Updated2026-05-26
  • Buy
Manufacturer Product number Product description Packaging Price Updated Buy
aablocks AA00GT8T 4-[(5-Methyl-1H-pyrazol-3-yl)amino]-2-phenyl-1(2H)-phthalazinone 5mg $53 2026-05-28 Buy
aablocks AA00GT8T 4-[(5-Methyl-1H-pyrazol-3-yl)amino]-2-phenyl-1(2H)-phthalazinone 10mg $75 2026-05-28 Buy
aablocks AA00GT8T Phthalazinonepyrazole ≥98% 1mg $119 2021-12-16 Buy
aablocks AA00GT8T 4-[(5-Methyl-1H-pyrazol-3-yl)amino]-2-phenyl-1(2H)-phthalazinone 25mg $130 2026-05-28 Buy
aablocks AA00GT8T 4-[(5-Methyl-1H-pyrazol-3-yl)amino]-2-phenyl-1(2H)-phthalazinone 50mg $179 2026-05-28 Buy
aablocks AA00GT8T 4-[(5-Methyl-1H-pyrazol-3-yl)amino]-2-phenyl-1(2H)-phthalazinone 100mg $271 2026-05-28 Buy
ACHEMBLOCK Y227216 Phthalazinone pyrazole 97.00% 25MG $160 2026-05-27 Buy
ACHEMBLOCK Y227216 Phthalazinone pyrazole 97.00% 100MG $375 2026-05-27 Buy
ApexBio Technology C3823 Phthalazinone pyrazole 10mg $572 2026-05-06 Buy
ApexBio Technology C3823 Phthalazinone pyrazole 5mg $323 2026-05-06 Buy
ApexBio Technology C3823 Phthalazinone pyrazole 1mg $67 2026-05-06 Buy
Arctom HY-12564 Phthalazinonepyrazole 98.0% 10mg $80 2026-05-26 Buy
Arctom HY-12564 Phthalazinonepyrazole 98.0% 10mM*1mLinDMSO(Solution) $55 2026-05-26 Buy
Arctom HY-12564 Phthalazinonepyrazole 98.0% 5mg $50 2026-05-26 Buy
Arctom HY-12564 Phthalazinonepyrazole 98.0% 10mM*1mLinDMSO(Solid+Solvent) $52 2026-05-26 Buy
Arctom HY-12564 Phthalazinonepyrazole 98.0% 50mg $241 2026-05-26 Buy

Properties

Boiling point :557.7±52.0 °C(Predicted)
Density :1.35±0.1 g/cm3(Predicted)
storage temp. :Store at -20°C
solubility :insoluble in EtOH; insoluble in H2O; ≥7.14 mg/mL in DMSO
form :crystalline solid
pka :13.83±0.10(Predicted)
color :Brown to gray

Safety Information

Symbol(GHS):
Signal word:
Hazard statements:
Code Hazard statements Hazard class Category Signal word Pictogram P-Codes
Precautionary statements:

Description

Three Aurora kinases, A-C, are involved in phosphorylation events that are critical for the completion of mitosis. Aurora A, involved in centrosomal assembly and acentrosomal spindle assembly, is overexpressed in many tumors. Phthalazinone pyrazole is a potent inhibitor of Aurora A kinase (IC50 = 31 nM). It does not inhibit Aurora B kinase at doses up to 100 μM. Phthalazinone pyrazole inhibits the proliferation of HCT116, Colo205, and MCF-7 cells (IC50 = 7.8, 2.9, and 1.6 μM, respectively).

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