TYRPHOSTIN AG 126
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- $10 - $2109
- Product name: TYRPHOSTIN AG 126
- CAS: 118409-62-4
- MF: C10H5N3O3
- MW: 215.16
- EINECS:
- MDL Number:MFCD00236448
- Synonyms:RARECHEM AL BX 0673;TYRPHOSTIN A10;TYRPHOSTIN AG 126;ag127 ;AG 126;ALPHA-CYANO-(3-HYDROXY-4-NITRO)CINNAMONITRILE;[3-HYDROXY-4-NITROBENZYLIDENE]MALONONITRILE;Tyrphostin 126
49 prices
Selected condition：
Brand
- aablocks
- ACHEMBLOCK
- AK Scientific
- Ambeed
- American Custom Chemicals Corporation
- ApexBio Technology
- Apolloscientific
- Biosynth
- Cayman Chemical
- Chem-Impex
- ChemScene
- Crysdot
- CSNpharm
- DC Chemicals
- Sigma-Aldrich
- TCI Chemical
- Thermo Scientific Chemicals
Package
- 1MG
- 2mg
- 5mg
- 10mg
- 25mg
- 50mg
- 100mg
- 250MG
- 1G
- 5G
- Manufactureraablocks
- Product numberAA007Q8C
- Product description2-(3-Hydroxy-4-nitrobenzylidene)malononitrile ≥98%
- Packaging5mg
- Price$10
- Updated2026-05-28
- Buy
- Manufactureraablocks
- Product numberAA007Q8C
- Product description2-(3-Hydroxy-4-nitrobenzylidene)malononitrile ≥98%
- Packaging10mg
- Price$11
- Updated2026-05-28
- Buy
- Manufactureraablocks
- Product numberAA007Q8C
- Product description2-(3-Hydroxy-4-nitrobenzylidene)malononitrile ≥98%
- Packaging25mg
- Price$17
- Updated2026-05-28
- Buy
- Manufactureraablocks
- Product numberAA007Q8C
- Product description2-(3-Hydroxy-4-nitrobenzylidene)malononitrile 99%
- Packaging100mg
- Price$48
- Updated2026-05-28
- Buy
- ManufacturerACHEMBLOCK
- Product numberQ65697
- Product description2-(3-hydroxy-4-nitrobenzylidene)malononitrile 98%
- Packaging250MG
- Price$150
- Updated2026-05-27
- Buy
- ManufacturerACHEMBLOCK
- Product numberQ65697
- Product description2-(3-hydroxy-4-nitrobenzylidene)malononitrile 98%
- Packaging1G
- Price$405
- Updated2026-05-27
- Buy
- ManufacturerACHEMBLOCK
- Product numberQ65697
- Product description2-(3-hydroxy-4-nitrobenzylidene)malononitrile 98%
- Packaging5G
- Price$1055
- Updated2026-05-27
- Buy
- ManufacturerAK Scientific
- Product number0073BA
- Product descriptionTyrphostin AG-126
- Packaging50mg
- Price$197
- Updated2021-12-16
- Buy
- ManufacturerAmbeed
- Product numberA860936
- Product descriptionAG 126 98%
- Packaging50mg
- Price$180
- Updated2021-12-16
- Buy
- ManufacturerAmbeed
- Product numberA860936
- Product descriptionAG 126 98%
- Packaging10mg
- Price$106
- Updated2021-12-16
- Buy
- ManufacturerAmbeed
- Product numberA860936
- Product descriptionAG 126 98%
- Packaging25mg
- Price$138
- Updated2021-12-16
- Buy
- ManufacturerAmbeed
- Product numberA860936
- Product descriptionAG 126 98%
- Packaging5mg
- Price$59
- Updated2021-12-16
- Buy
- ManufacturerAmerican Custom Chemicals Corporation
- Product numberKIN0000256
- Product descriptionTYRPHOSTIN A-10 95.00%
- Packaging1MG
- Price$432
- Updated2021-12-16
- Buy
- ManufacturerAmerican Custom Chemicals Corporation
- Product numberKIN0000256
- Product descriptionTYRPHOSTIN A-10 95.00%
- Packaging25MG
- Price$1034.48
- Updated2021-12-16
- Buy
- ManufacturerAmerican Custom Chemicals Corporation
- Product numberKIN0000256
- Product descriptionTYRPHOSTIN A-10 95.00%
- Packaging5MG
- Price$703.86
- Updated2021-12-16
- Buy
- ManufacturerApexBio Technology
- Product numberC4338
- Product descriptionAG-126
- Packaging25mg
- Price$355
- Updated2026-05-06
- Buy
| Manufacturer | Product number | Product description | Packaging | Price | Updated | Buy |
|---|---|---|---|---|---|---|
| aablocks | AA007Q8C | 2-(3-Hydroxy-4-nitrobenzylidene)malononitrile ≥98% | 5mg | $10 | 2026-05-28 | Buy |
| aablocks | AA007Q8C | 2-(3-Hydroxy-4-nitrobenzylidene)malononitrile ≥98% | 10mg | $11 | 2026-05-28 | Buy |
| aablocks | AA007Q8C | 2-(3-Hydroxy-4-nitrobenzylidene)malononitrile ≥98% | 25mg | $17 | 2026-05-28 | Buy |
| aablocks | AA007Q8C | 2-(3-Hydroxy-4-nitrobenzylidene)malononitrile 99% | 100mg | $48 | 2026-05-28 | Buy |
| ACHEMBLOCK | Q65697 | 2-(3-hydroxy-4-nitrobenzylidene)malononitrile 98% | 250MG | $150 | 2026-05-27 | Buy |
| ACHEMBLOCK | Q65697 | 2-(3-hydroxy-4-nitrobenzylidene)malononitrile 98% | 1G | $405 | 2026-05-27 | Buy |
| ACHEMBLOCK | Q65697 | 2-(3-hydroxy-4-nitrobenzylidene)malononitrile 98% | 5G | $1055 | 2026-05-27 | Buy |
| AK Scientific | 0073BA | Tyrphostin AG-126 | 50mg | $197 | 2021-12-16 | Buy |
| Ambeed | A860936 | AG 126 98% | 50mg | $180 | 2021-12-16 | Buy |
| Ambeed | A860936 | AG 126 98% | 10mg | $106 | 2021-12-16 | Buy |
| Ambeed | A860936 | AG 126 98% | 25mg | $138 | 2021-12-16 | Buy |
| Ambeed | A860936 | AG 126 98% | 5mg | $59 | 2021-12-16 | Buy |
| American Custom Chemicals Corporation | KIN0000256 | TYRPHOSTIN A-10 95.00% | 1MG | $432 | 2021-12-16 | Buy |
| American Custom Chemicals Corporation | KIN0000256 | TYRPHOSTIN A-10 95.00% | 25MG | $1034.48 | 2021-12-16 | Buy |
| American Custom Chemicals Corporation | KIN0000256 | TYRPHOSTIN A-10 95.00% | 5MG | $703.86 | 2021-12-16 | Buy |
| ApexBio Technology | C4338 | AG-126 | 25mg | $355 | 2026-05-06 | Buy |
Properties
storage temp. :Keep in dark place,Inert atmosphere,Store in freezer, under -20°C
solubility :≤0.15mg/ml in ethanol;10mg/ml in DMSO;10mg/ml in dimethyl formamide
form :Yellow solid
color :Light yellow to yellow
Sensitive :Light Sensitive
InChI :1S/C10H5N3O3/c11-5-8(6-12)3-7-1-2-9(13(15)16)10(14)4-7/h1-4,14H
InChIKey :DUQADSPERJRQBW-UHFFFAOYSA-N
SMILES :[N+](=O)([O-])c1c(cc(cc1)C=C(C#N)C#N)O
solubility :≤0.15mg/ml in ethanol;10mg/ml in DMSO;10mg/ml in dimethyl formamide
form :Yellow solid
color :Light yellow to yellow
Sensitive :Light Sensitive
InChI :1S/C10H5N3O3/c11-5-8(6-12)3-7-1-2-9(13(15)16)10(14)4-7/h1-4,14H
InChIKey :DUQADSPERJRQBW-UHFFFAOYSA-N
SMILES :[N+](=O)([O-])c1c(cc(cc1)C=C(C#N)C#N)O
Safety Information
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| Signal word: | Danger | |||||||||||||||||||||||||||||||||||||||||||||||||
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Description
Tyrphostins are a family of protein tyrosine kinase inhibitors originally developed to inhibit cell growth by blocking the activity of certain growth factor receptor kinases (GFRK). The tyrphostin AG-126 selectively inhibits the phosphorylation of ERK1 (p44) and ERK2 (p42) at 25-50 μM. It blocks the production of TNF-α in vitro and in vivo, attenuating signaling through NF-κB, the induced expression of COX-2 and iNOS, and the inflammatory response in diverse animal models. AG-126 is a poor inhibitor of epidermal GFRK (IC50 = 450 μM) and platelet-derived GFRK (IC50 > 100 μM).Related product price
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