Tandutinib
|
- $45 - $2500
- Product name: Tandutinib
- CAS: 387867-13-2
- MF: C31H42N6O4
- MW: 562.7
- EINECS:
- MDL Number:MFCD09954147
- Synonyms:Tandutinib;1-Piperazinecarboxamide, 4-(6-methoxy-7-(3-(1-piperidinyl)propoxy)-4-quinazolinyl)-N-(4-(1-methylethoxy)phenyl)-;4-(6-Methoxy-7-(3-piperidin-1-ylpropoxy)quinazolin-4-yl)piperazine-1-carboxylic acid (4-isopropoxyphenyl)amide;Unii-E1io3icj9a;Tandutinib(CT 53518);Tandutinib (MLN518);CT53518; MLN518;Tandutinib(TINIBS)
52 prices
Selected condition：
Brand
- Adipogen Life Sciences
- ApexBio Technology
- Arctom
- AvaChem
- Axon Medchem
- Biosynth Carbosynth
- Cayman Chemical
- ChemScene
- Crysdot
- CSNpharm
- DC Chemicals
- Matrix Scientific
- Medical Isotopes, Inc.
- Sigma-Aldrich
- TRC
- Usbiological
Package
- 10mM(in 1mL DMSO)
- 1mg
- 10mM(in1mLDMSO)
- 2.5mg
- 5mg
- 10mg
- 20mg
- 25mg
- 50mg
- 100.00mg
- 100mg
- 200mg
- 250.00mg
- 250mg
- 500mg
- 1g
- 1.00g
- ManufacturerAdipogen Life Sciences
- Product numberSYN-1088-M001
- Product descriptionTandutinib ≥95%
- Packaging1mg
- Price$54
- Updated2026-05-06
- Buy
- ManufacturerAdipogen Life Sciences
- Product numberSYN-1088-M005
- Product descriptionTandutinib ≥95%
- Packaging5mg
- Price$70
- Updated2026-05-06
- Buy
- ManufacturerAdipogen Life Sciences
- Product numberSYN-1088-M010
- Product descriptionTandutinib ≥95%
- Packaging10mg
- Price$81
- Updated2021-12-16
- Buy
- ManufacturerAdipogen Life Sciences
- Product numberSYN-1088-M010
- Product descriptionTandutinib ≥95%
- Packaging10mg
- Price$81
- Updated2026-05-06
- Buy
- ManufacturerAdipogen Life Sciences
- Product numberSYN-1088-M050
- Product descriptionTandutinib ≥95%
- Packaging50mg
- Price$97
- Updated2026-05-06
- Buy
- ManufacturerAdipogen Life Sciences
- Product numberSYN-1088-M100
- Product descriptionTandutinib ≥95%
- Packaging100mg
- Price$130
- Updated2026-05-06
- Buy
- ManufacturerApexBio Technology
- Product numberB7853
- Product descriptionTandutinib(MLN518)HCl
- Packaging200mg
- Price$140
- Updated2021-12-16
- Buy
- ManufacturerApexBio Technology
- Product numberB7853
- Product descriptionTandutinib (MLN518) HCl
- Packaging200mg
- Price$140
- Updated2026-05-06
- Buy
- ManufacturerApexBio Technology
- Product numberB1526
- Product descriptionTandutinib (MLN518)
- Packaging200mg
- Price$140
- Updated2026-05-06
- Buy
- ManufacturerApexBio Technology
- Product numberB7853
- Product descriptionTandutinib (MLN518) HCl
- Packaging100mg
- Price$80
- Updated2026-05-06
- Buy
- ManufacturerApexBio Technology
- Product numberB1526
- Product descriptionTandutinib (MLN518)
- Packaging100mg
- Price$80
- Updated2026-05-06
- Buy
- ManufacturerApexBio Technology
- Product numberB1526
- Product descriptionTandutinib(MLN518)
- Packaging10mM(in 1mL DMSO)
- Price$50
- Updated2021-12-16
- Buy
- ManufacturerApexBio Technology
- Product numberB1526
- Product descriptionTandutinib (MLN518)
- Packaging10mM(in1mLDMSO)
- Price$50
- Updated2026-05-06
- Buy
- ManufacturerApexBio Technology
- Product numberB7853
- Product descriptionTandutinib (MLN518) HCl
- Packaging500mg
- Price$260
- Updated2026-05-06
- Buy
- ManufacturerApexBio Technology
- Product numberB1526
- Product descriptionTandutinib (MLN518)
- Packaging500mg
- Price$260
- Updated2026-05-06
- Buy
- ManufacturerArctom
- Product numberCFN60446
- Product descriptionTandutinib(MLN518)
- Packaging20mg
- Price$98
- Updated2021-12-16
- Buy
| Manufacturer | Product number | Product description | Packaging | Price | Updated | Buy |
|---|---|---|---|---|---|---|
| Adipogen Life Sciences | SYN-1088-M001 | Tandutinib ≥95% | 1mg | $54 | 2026-05-06 | Buy |
| Adipogen Life Sciences | SYN-1088-M005 | Tandutinib ≥95% | 5mg | $70 | 2026-05-06 | Buy |
| Adipogen Life Sciences | SYN-1088-M010 | Tandutinib ≥95% | 10mg | $81 | 2021-12-16 | Buy |
| Adipogen Life Sciences | SYN-1088-M010 | Tandutinib ≥95% | 10mg | $81 | 2026-05-06 | Buy |
| Adipogen Life Sciences | SYN-1088-M050 | Tandutinib ≥95% | 50mg | $97 | 2026-05-06 | Buy |
| Adipogen Life Sciences | SYN-1088-M100 | Tandutinib ≥95% | 100mg | $130 | 2026-05-06 | Buy |
| ApexBio Technology | B7853 | Tandutinib(MLN518)HCl | 200mg | $140 | 2021-12-16 | Buy |
| ApexBio Technology | B7853 | Tandutinib (MLN518) HCl | 200mg | $140 | 2026-05-06 | Buy |
| ApexBio Technology | B1526 | Tandutinib (MLN518) | 200mg | $140 | 2026-05-06 | Buy |
| ApexBio Technology | B7853 | Tandutinib (MLN518) HCl | 100mg | $80 | 2026-05-06 | Buy |
| ApexBio Technology | B1526 | Tandutinib (MLN518) | 100mg | $80 | 2026-05-06 | Buy |
| ApexBio Technology | B1526 | Tandutinib(MLN518) | 10mM(in 1mL DMSO) | $50 | 2021-12-16 | Buy |
| ApexBio Technology | B1526 | Tandutinib (MLN518) | 10mM(in1mLDMSO) | $50 | 2026-05-06 | Buy |
| ApexBio Technology | B7853 | Tandutinib (MLN518) HCl | 500mg | $260 | 2026-05-06 | Buy |
| ApexBio Technology | B1526 | Tandutinib (MLN518) | 500mg | $260 | 2026-05-06 | Buy |
| Arctom | CFN60446 | Tandutinib(MLN518) | 20mg | $98 | 2021-12-16 | Buy |
Properties
Melting point :177-178°C
Boiling point :769.5±60.0 °C(Predicted)
Density :1.213±0.06 g/cm3(Predicted)
storage temp. :Sealed in dry,Store in freezer, under -20°C
solubility :Chloroform (Slightly), Methanol (Slightly)
pka :13.39±0.70(Predicted)
form :Solid
color :White to Off-White
Water Solubility :H2O: 2mg/mL, clear
InChIKey :UXXQOJXBIDBUAC-UHFFFAOYSA-N
SMILES :N1(C(NC2=CC=C(OC(C)C)C=C2)=O)CCN(C2=C3C(=NC=N2)C=C(OCCCN2CCCCC2)C(OC)=C3)CC1
CAS DataBase Reference :387867-13-2(CAS DataBase Reference)
Boiling point :769.5±60.0 °C(Predicted)
Density :1.213±0.06 g/cm3(Predicted)
storage temp. :Sealed in dry,Store in freezer, under -20°C
solubility :Chloroform (Slightly), Methanol (Slightly)
pka :13.39±0.70(Predicted)
form :Solid
color :White to Off-White
Water Solubility :H2O: 2mg/mL, clear
InChIKey :UXXQOJXBIDBUAC-UHFFFAOYSA-N
SMILES :N1(C(NC2=CC=C(OC(C)C)C=C2)=O)CCN(C2=C3C(=NC=N2)C=C(OCCCN2CCCCC2)C(OC)=C3)CC1
CAS DataBase Reference :387867-13-2(CAS DataBase Reference)
Safety Information
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Description
Tandutinib is a potent antagonist of platelet-derived growth factor receptor β (PDGFRβ), FLT3, and c-Kit (IC50 = 200, 220, and 170 nM, respectively). It less potently inhibits macrophage colony-stimulating factor 1 receptor (IC50 = 3.4 μM) and does not significantly inhibit other tyrosine or serine/threonine kinases. Tandutinib blocks the growth of cells expressing an internal tandem duplication within the juxtamembrane domain of the FLT3 receptor, found in some acute myelogenous leukemia cells. It also impairs the growth of colon cancer cells through its actions on the c-Kit receptor. Tandutinib reverses multidrug resistance in vitro by impairing the efflux activity of the multidrug resistance protein 7.Related product price
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