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ChemicalBook >> CAS DataBase List >> Dasatinib

Dasatinib

Dasatinib price.
  • $9 - $4498.73
  • Product name: Dasatinib
  • CAS: 302962-49-8
  • MF: C22H26ClN7O2S
  • MW: 488.01
  • EINECS:801-607-0
  • MDL Number:MFCD11046566
  • Synonyms:SPRYCEL;BMS354825;DASATINIB (BMS 354825);CS-1968;N-(2-chloro-6-Methylphenyl)-2-[[6-[4-(2-hydroxyethyl)-1-piperazinyl]-2-Methyl-4-pyriMidinyl]aMino]-1,3-thiazole-5-carboxaMide;sprycel Dasatinib;BMS-354825; SPRYCEL;25MG/100MG/1G;NCGC00181129;Dasatinib (Dasatinib Monohydrate) Tablet
125 prices
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Brand
  • aablocks
  • AccelPharmtech
  • Adipogen Life Sciences
  • AK Scientific
  • Ambeed
  • American Custom Chemicals Corporation
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  • Sigma-Aldrich
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  • 10mM(in1mLDMSO)
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  • 100.00g
  • Manufactureraablocks
  • Product numberAA002ZGV
  • Product descriptionN-(2-Chloro-6-methylphenyl)-2-[[6-[4-(2-hydroxyethyl)piperazin-1-yl]-2-methylpyrimidin-4-yl]amino]-1,3-thiazole-5-carboxamide ≥99%
  • Packaging100mg
  • Price$11
  • Updated2026-05-28
  • Buy
  • Manufactureraablocks
  • Product numberAA002ZGV
  • Product descriptionN-(2-Chloro-6-methylphenyl)-2-[[6-[4-(2-hydroxyethyl)piperazin-1-yl]-2-methylpyrimidin-4-yl]amino]-1,3-thiazole-5-carboxamide ≥99%
  • Packaging500mg
  • Price$14
  • Updated2026-05-28
  • Buy
  • Manufactureraablocks
  • Product numberAA002ZGV
  • Product descriptionN-(2-Chloro-6-methylphenyl)-2-[[6-[4-(2-hydroxyethyl)piperazin-1-yl]-2-methylpyrimidin-4-yl]amino]-1,3-thiazole-5-carboxamide ≥99%
  • Packaging1g
  • Price$15
  • Updated2026-05-28
  • Buy
  • Manufactureraablocks
  • Product numberAA002ZGV
  • Product descriptionN-(2-Chloro-6-methylphenyl)-2-[[6-[4-(2-hydroxyethyl)piperazin-1-yl]-2-methylpyrimidin-4-yl]amino]-1,3-thiazole-5-carboxamide ≥99%
  • Packaging25mg
  • Price$10
  • Updated2026-05-28
  • Buy
  • Manufactureraablocks
  • Product numberAA002ZGV
  • Product descriptionN-(2-Chloro-6-methylphenyl)-2-[[6-[4-(2-hydroxyethyl)piperazin-1-yl]-2-methylpyrimidin-4-yl]amino]-1,3-thiazole-5-carboxamide 98%
  • Packaging5g
  • Price$64
  • Updated2026-05-28
  • Buy
  • Manufactureraablocks
  • Product numberAA002ZGV
  • Product descriptionN-(2-Chloro-6-methylphenyl)-2-[[6-[4-(2-hydroxyethyl)piperazin-1-yl]-2-methylpyrimidin-4-yl]amino]-1,3-thiazole-5-carboxamide 98%
  • Packaging25g
  • Price$190
  • Updated2026-05-28
  • Buy
  • ManufacturerAccelPharmtech
  • Product numberAT8021
  • Product description5-Thiazolecarboxamide, N-(2-chloro-6-methylphenyl)-2-[[6-[4-(2-hydroxyethyl)-1-piperazinyl]-2-methyl-4-pyrimidinyl]amino]- 98.00%
  • Packaging1G
  • Price$210
  • Updated2026-05-21
  • Buy
  • ManufacturerAdipogen Life Sciences
  • Product numberSYN-1036-M005
  • Product descriptionDasatinib ≥95%
  • Packaging5mg
  • Price$70
  • Updated2021-12-16
  • Buy
  • ManufacturerAdipogen Life Sciences
  • Product numberSYN-1036-M010
  • Product descriptionDasatinib ≥95%
  • Packaging10mg
  • Price$97
  • Updated2021-12-16
  • Buy
  • ManufacturerAdipogen Life Sciences
  • Product numberAG-CR1-3540-M250
  • Product descriptionDasatinib ≥98%(HPLC)
  • Packaging250mg
  • Price$130
  • Updated2026-05-06
  • Buy
  • ManufacturerAdipogen Life Sciences
  • Product numberAG-CR1-3540-M010
  • Product descriptionDasatinib ≥98%(HPLC)
  • Packaging10mg
  • Price$25
  • Updated2026-05-06
  • Buy
  • ManufacturerAdipogen Life Sciences
  • Product numberAG-CR1-3540-M050
  • Product descriptionDasatinib ≥98%(HPLC)
  • Packaging50mg
  • Price$40
  • Updated2026-05-06
  • Buy
  • ManufacturerAK Scientific
  • Product numberJ10239
  • Product descriptionDasatinib
  • Packaging25mg
  • Price$39
  • Updated2021-12-16
  • Buy
  • ManufacturerAK Scientific
  • Product numberJ10239
  • Product descriptionDasatinib 99%(HPLC)
  • Packaging25mg
  • Price$42
  • Updated2026-06-04
  • Buy
  • ManufacturerAK Scientific
  • Product numberJ10239
  • Product descriptionDasatinib 99%(HPLC)
  • Packaging10mg
  • Price$27
  • Updated2026-06-04
  • Buy
  • ManufacturerAK Scientific
  • Product numberS104
  • Product descriptionDasatinib 98%(HPLC)
  • Packaging1g
  • Price$28
  • Updated2026-06-04
  • Buy
Manufacturer Product number Product description Packaging Price Updated Buy
aablocks AA002ZGV N-(2-Chloro-6-methylphenyl)-2-[[6-[4-(2-hydroxyethyl)piperazin-1-yl]-2-methylpyrimidin-4-yl]amino]-1,3-thiazole-5-carboxamide ≥99% 100mg $11 2026-05-28 Buy
aablocks AA002ZGV N-(2-Chloro-6-methylphenyl)-2-[[6-[4-(2-hydroxyethyl)piperazin-1-yl]-2-methylpyrimidin-4-yl]amino]-1,3-thiazole-5-carboxamide ≥99% 500mg $14 2026-05-28 Buy
aablocks AA002ZGV N-(2-Chloro-6-methylphenyl)-2-[[6-[4-(2-hydroxyethyl)piperazin-1-yl]-2-methylpyrimidin-4-yl]amino]-1,3-thiazole-5-carboxamide ≥99% 1g $15 2026-05-28 Buy
aablocks AA002ZGV N-(2-Chloro-6-methylphenyl)-2-[[6-[4-(2-hydroxyethyl)piperazin-1-yl]-2-methylpyrimidin-4-yl]amino]-1,3-thiazole-5-carboxamide ≥99% 25mg $10 2026-05-28 Buy
aablocks AA002ZGV N-(2-Chloro-6-methylphenyl)-2-[[6-[4-(2-hydroxyethyl)piperazin-1-yl]-2-methylpyrimidin-4-yl]amino]-1,3-thiazole-5-carboxamide 98% 5g $64 2026-05-28 Buy
aablocks AA002ZGV N-(2-Chloro-6-methylphenyl)-2-[[6-[4-(2-hydroxyethyl)piperazin-1-yl]-2-methylpyrimidin-4-yl]amino]-1,3-thiazole-5-carboxamide 98% 25g $190 2026-05-28 Buy
AccelPharmtech AT8021 5-Thiazolecarboxamide, N-(2-chloro-6-methylphenyl)-2-[[6-[4-(2-hydroxyethyl)-1-piperazinyl]-2-methyl-4-pyrimidinyl]amino]- 98.00% 1G $210 2026-05-21 Buy
Adipogen Life Sciences SYN-1036-M005 Dasatinib ≥95% 5mg $70 2021-12-16 Buy
Adipogen Life Sciences SYN-1036-M010 Dasatinib ≥95% 10mg $97 2021-12-16 Buy
Adipogen Life Sciences AG-CR1-3540-M250 Dasatinib ≥98%(HPLC) 250mg $130 2026-05-06 Buy
Adipogen Life Sciences AG-CR1-3540-M010 Dasatinib ≥98%(HPLC) 10mg $25 2026-05-06 Buy
Adipogen Life Sciences AG-CR1-3540-M050 Dasatinib ≥98%(HPLC) 50mg $40 2026-05-06 Buy
AK Scientific J10239 Dasatinib 25mg $39 2021-12-16 Buy
AK Scientific J10239 Dasatinib 99%(HPLC) 25mg $42 2026-06-04 Buy
AK Scientific J10239 Dasatinib 99%(HPLC) 10mg $27 2026-06-04 Buy
AK Scientific S104 Dasatinib 98%(HPLC) 1g $28 2026-06-04 Buy

Properties

Melting point :275-286°C
Density :1.408±0.06 g/cm3(Predicted)
storage temp. :Sealed in dry,Store in freezer, under -20°C
solubility :Soluble in DMSO (up to 200 mg/ml).
pka :10.94±0.70(Predicted)
form :White powder.
color :White or off-white
Stability :Stable for 1 year from date of purchase as supplied. Solutions in DMSO may be stored at -20° for up to 2 months.
InChIKey :ZBNZXTGUTAYRHI-UHFFFAOYSA-N
SMILES :S1C(C(NC2=C(C)C=CC=C2Cl)=O)=CN=C1NC1C=C(N2CCN(CCO)CC2)N=C(C)N=1
CAS DataBase Reference :302962-49-8(CAS DataBase Reference)

Safety Information

Symbol(GHS): Corrosion (GHS05)Health Hazard (GHS08)Environment (GHS09)
Signal word: Danger
Hazard statements:
Code Hazard statements Hazard class Category Signal word Pictogram P-Codes
H315 Causes skin irritation Skin corrosion/irritation Category 2 Warning P264, P280, P302+P352, P321,P332+P313, P362
H318 Causes serious eye damage Serious eye damage/eye irritation Category 1 Danger P280, P305+P351+P338, P310
H351 Suspected of causing cancer Carcinogenicity Category 2 Warning P201, P202, P281, P308+P313, P405,P501
H372 Causes damage to organs through prolonged or repeated exposure Specific target organ toxicity, repeated exposure Category 1 Danger P260, P264, P270, P314, P501
H410 Very toxic to aquatic life with long lasting effects Hazardous to the aquatic environment, long-term hazard Category 1 Warning P273, P391, P501
Precautionary statements:
P202 Do not handle until all safety precautions have been read and understood.
P273 Avoid release to the environment.
P280 Wear protective gloves/protective clothing/eye protection/face protection.
P302+P352 IF ON SKIN: wash with plenty of soap and water.
P305+P351+P338 IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continuerinsing.
P308+P313 IF exposed or concerned: Get medical advice/attention.

Description

Dasatinib is a potent inhibitor of the non-receptor tyrosine kinases Abl and Src as well as other members of the Src family. It is effective at sub-nanomolar concentrations, inhibiting Src, Abl, and Lck with IC50 values of 0.05, 0.5, and 0.4 nM, respectively. At nanomolar concentrations, dasatinib also blocks the activity of several other receptor and non-receptor tyrosine kinases, plus drug resistant mutants. Because of these activities, dasatinib has potential therapeutic value in diseases that are characterized by elevated levels of these kinases, including some forms of cancer and fibrotic disease.

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