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ApexBio Technology
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Cas:1231930-82-7
ProductName:LY2835219
Brand:apexbt | Product Number:A1794
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| Company Name: |
Adipogen Life Sciences
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41-6192660-40 |
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Cas:1231930-82-7
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https://hanhongsci.com/
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021-54306202 18917919676 |
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Cas:1231930-82-7
ProductName:LY2835219
Purity: 98+% | Package: 5mg;25mg;100mg;1g;5g
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| Company Name: |
Adipogen Corporation
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(858) 457-8383 |
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Cas:1231930-82-7
ProductName:LY2835219
Brand:adipogen | Product Number:CDX-L0303-M250 | Purity:≥99%
|
- LY2835219 intermediate
-
- $0.00 / 25kg
-
2025-12-01
- CAS:1231930-42-9
- Min. Order: 1kg
- Purity: 98%
- Supply Ability: 1000kg
- Abemaciclib;LY2835219
-
- $585.00 / 1g
-
2024-11-01
- CAS:1231929-97-7
- Min. Order: 1g
- Purity: 98%+
- Supply Ability: 100kgs
- LY2835219
-
- $7.00 / 1KG
-
2019-12-31
- CAS:1231930-82-7
- Min. Order: 1KG
- Purity: 99%
- Supply Ability: 100KG
|
| Product Name: | Ly2835219 | | Synonyms: | 2-Pyrimidinamine, N-[5-[(4-ethyl-1-piperazinyl)methyl]-2-pyridinyl]-5-fluoro-4-[4-fluoro-2-methyl-1-(1-methylethyl)-1H-benzimidazol-6-yl]-, methanesulfonate (1:1);N-[5-[(4-Ethyl-1-piperazinyl)methyl]-2-pyridinyl]-5-fluoro-4-[4-fluoro-2-methyl-1-(1-methylethyl)-1H-benzimidazol-6-yl]-2-pyrimidinamine methanesulfonate (1:1) LY2835219;LY2835219 mesylate;Bemaciclib(salt);N-[5-[(4-ethylpiperazin-1-yl)methyl]pyridin-2-yl]-5-fluoro-4-(7-fluoro-2-methyl-3-propan-2-ylbenzimidazol-5-yl)pyrimidin-2-amine,methanesulfonic acid;N-(5-((4-Ethylpiperazin-1-yl)methyl)pyridin-2-yl)-5-fluoro-4-(4-fluoro-1-isopropyl-2-methyl-1H-benzo[d]imidazol-6-yl)pyrimidin-2-amine methanesulfonate;N-[5-[(4-Ethyl-1-piperazinyl)methyl]-2-pyridinyl]-5-fluoro-4-[4-fluoro-2-methyl-1-(1-methyle;LY2835219 Ms salt, Abemaciclib Ms salt | | CAS: | 1231930-82-7 | | MF: | C28H36F2N8O3S | | MW: | 602.71 | | EINECS: | | | Product Categories: | Inhibitors | | Mol File: | 1231930-82-7.mol |  |
| | Ly2835219 Chemical Properties |
| storage temp. | -20° | | solubility | Soluble in DMSO (up to at least 25 mg/ml) or in Water (up to at least 25 mg/ml). | | form | solid | | color | Off-white | | Stability: | Stable for 1 year from date of purchase as supplied. Solutions in DMSO or distilled water may be stored at -20° for up to 1 month. | | CAS DataBase Reference | 1231930-82-7 |
| | Ly2835219 Usage And Synthesis |
| Description | Abemaciclib (LY2835219) is a selective CDK4/6 inhibitor with IC50 values of 2 nM and 10 nM for CDK4 and CDK6, respectively. | | Mechanism of action | Through this mechanism, LY2835219 blocks phosphorylation of retinoblastoma protein, resulting in arrest of cell cycling in the G1 phase. LY2835219 has antitumor action against xenografts when used alone or in combination with other chemotherapeutic compounds. |
| | Ly2835219 Preparation Products And Raw materials |
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