| Company Name: |
Hangzhou J&H Chemical Co., Ltd.
|
| Tel: |
0571-87396432 |
| Email: |
sales@jhechem.com |
| Products Intro: |
Cas:19237-84-4
ProductName:Prazosin Hcl
Purity: 98% HPLC | Package: 50KG;10KG;5KG;1KG;500g;100g;10g;1g;
|
| Company Name: |
Selleck Chemicals
|
| Tel: |
400-668-6834 |
| Email: |
info@selleck.cn |
| Products Intro: |
Cas:19237-84-4
ProductName:Prazosin HCl
|
| Company Name: |
Adooq Bioscience LLC
|
| Tel: |
400-025-6535 |
| Email: |
sales@adooq.cn |
| Products Intro: |
Cas:19237-84-4
ProductName:Prazosin HCl
|
| Company Name: |
Biorbyt Ltd.
|
| Tel: |
+44 (0)1223 859 353 |
| Email: |
info@biorbyt.com |
| Products Intro: |
Cas:19237-84-4
ProductName:Prazosin HCl
|
- Prazosin
-
- $35.00
-
2024-03-15
- CAS:19216-56-9
- Min. Order: 1kg
- Purity: 99.8%
- Supply Ability: 200tons/year
- Prazosin
-
- $15.00
-
2021-07-13
- CAS:19216-56-9
- Min. Order: 1KG
- Purity: 99%+ HPLC
- Prazosin
-
-
2020-05-10
- CAS:19216-56-9
- Min. Order: 1KG
- Purity: 99.0%
- Supply Ability: 500 MT
|
| | Prazosin Hcl Basic information |
| Product Name: | Prazosin Hcl | | Synonyms: | 4-Amino-2-pyroyl-6,7-dimetoxypiperazin-1-yl-chynazolina hydrochloride;Furazosin hydrochloride, 1-(4-Amino-6,7-dimethoxy-2-quinazolinyl)-4-(2-furanylcarbonyl)piperazine hydrochloride;[4-(4-Amino-6,7-dimethoxy-quinazolin-2-yl)piperazin-1-yl]-(2-furyl)methanone hydrochloride;Prazosin hydrochloride,1-(4-Amino-6,7-dimethoxy-2-quinazolinyl)-4-(2-furanylcarbonyl)piperazine hydrochloride, Furazosin hydrochloride;Prazosin Hydrochloride (500 mg);Prazosin hydrochlori;1-(4-amino-6,7-dimethoxy-2-quinazolinyl)-4-(2-furanylcarbonyl)piperazinehydr;[4-(4-AMino-6,7-diMethoxy-2-quinazolinyl)-1-piperazinyl]-2-furanylMethanone Hydrochloride | | CAS: | 19237-84-4 | | MF: | C19H22ClN5O4 | | MW: | 419.86 | | EINECS: | 242-903-4 | | Product Categories: | Adrenoceptors;MINIPRESS;Amines;Bases & Related Reagents;Heterocycles;Nucleotides;Adrenoceptor;Intermediates & Fine Chemicals;Pharmaceuticals | | Mol File: | 19237-84-4.mol |  |
| | Prazosin Hcl Chemical Properties |
| Melting point | 277 - 280 °C | | storage temp. | 2-8°C | | solubility | H2O: 1 mg/mL, clear, colorless | | form | solid | | color | white | | Water Solubility | Soluble in dimethyl sulfoxide, ethanol, water, methanol. | | Merck | 14,7717 | | BRN | 4303561 | | InChI | InChI=1S/C19H21N5O4.ClH/c1-26-15-10-12-13(11-16(15)27-2)21-19(22-17(12)20)24-7-5-23(6-8-24)18(25)14-4-3-9-28-14;/h3-4,9-11H,5-8H2,1-2H3,(H2,20,21,22);1H | | InChIKey | WFXFYZULCQKPIP-UHFFFAOYSA-N | | SMILES | N1(C2=NC(N)=C3C(=N2)C=C(OC)C(OC)=C3)CCN(C(C2=CC=CO2)=O)CC1.[H]Cl | | CAS DataBase Reference | 19237-84-4(CAS DataBase Reference) |
| Hazard Codes | Xn | | Risk Statements | 22-36/37/38-62 | | Safety Statements | 28-36 | | RIDADR | 3249 | | WGK Germany | 3 | | RTECS | VA1350000 | | F | 10 | | HazardClass | 6.1(b) | | PackingGroup | III | | HS Code | 2934990002 | | Storage Class | 11 - Combustible Solids | | Hazard Classifications | Repr. 2
STOT RE 2
STOT SE 3 | | Hazardous Substances Data | 19237-84-4(Hazardous Substances Data) | | Toxicity | dog,LD50,oral,> 700mg/kg (700mg/kg),GASTROINTESTINAL: CHANGES IN STRUCTURE OR FUNCTION OF SALIVARY GLANDSKIDNEY, URETER, AND BLADDER: OTHER CHANGES GASTROINTESTINAL: NAUSEA OR VOMITING,Oyo Yakuri. Pharmacometrics. Vol. 17, Pg. 39, 1979. |
| | Prazosin Hcl Usage And Synthesis |
| Description | Prazosin Hcl, a quinazoline derivative, is the first of a new chemical class of antihypertensives.
| | Physical properties |
Prazosin Hcl is a white, crystalline substance, slightly soluble in water and isotonic saline, and has a molecular weight of 419.87.
| | Uses |
Prazosin Hcl is indicated for the treatment of hypertension, to lower blood pressure. It can be used alone or in combination with other antihypertensive drugs such as diuretics or beta-adrenergic blocking agents.
| | Brand name | Minipress (Pfizer) | | Biological Activity |
α 1 and α 2B -adrenoceptor antagonist. Also a potent antagonist at the melatonin MT 3 receptor (K i = 10.2 nM). Also available as part of the α 1 -Adrenoceptor Tocriset™ and Mixed Adrenergic Tocriset™ .
| | Biochem/physiol Actions | Peripheral α1-adrenoceptor antagonist; vasodilator. Prazosin Hcl can be used to treat chronic posttraumatic stress disorder (PTSD). It plays a role in reducing blood pressure by relaxing blood vessels, hence used in the treatment of high blood pressure.
| | Side effects | Headache, drowsiness, tiredness, weakness, blurred vision, nausea, vomiting, diarrhea, or constipation
|
| | Prazosin Hcl Preparation Products And Raw materials |
|