Terbinafine Hcl

Terbinafine Hcl Suppliers list

Company Name:	Guangzhou TongYi biochemistry technology Co.,LTD
Tel:
Email:	tongyibiochem@163.com
Products Intro:	Cas:78628-80-5 ProductName:terbinafine hcl Purity: 99% \| Package: 1g,10g,100g,500g,1kg,25kg,100kg,500kg

Company Name:	Shanghai Amole Biotechnology Co., Ltd.
Tel:	13370042665 18916960931
Email:	2596183085@qq.com
Products Intro:	Cas:78628-80-5 ProductName:Terbinafine HCl Purity: 10mM in DMSO \| Package: 1ml

Company Name:	Shanghai?Medlife?Pharm-Tech?Co.,?Ltd
Tel:	4000862158 18117107507
Email:	vip@med-life.cn
Products Intro:	Cas:78628-80-5 ProductName:Terbinafine HCl Purity: >=98% \| Package: 200mg;10mM (in 1mL DMSO);100mg

Company Name:	Shandong Yuhe Pharmaceutical Technology Co., LTD
Tel:	15263077727
Email:	1436425847@qq.com
Products Intro:	Cas:78628-80-5 ProductName:Terbinafine HCl Purity: 99% \| Package: 5KG;1KG

Company Name:	Shandong Yinfeida Pharmaceutical Co.Ltd
Tel:	13639499855
Email:	455422263@qq.com
Products Intro:	Cas:78628-80-5 ProductName:Terbinafine HCL Purity: 99% \| Package: 1KG;20KG;25KG

Terbinafine Hcl manufacturers

Terbinafine Hydrochloride Cream: Indications, Usage and Adverse Reactions
Terbinafine Hydrochloride Cream is an FDA-approved antifungal medication used for the treatment of topical skin fungal infecti....
Dec 16，2024

How to increase the solubility of terbinafine hydrochloride
The poor water solubility of terbinafine hydrochloride leads to reduced oral bioavailability, so attempts were made to improve....
Dec 14，2023

What does Terbinafine Hydrochloride treat?
Terbinafine is an oral antifungal agent used to treat fungal infections of the hair, nails, and skin. It is also used to treat....
Nov 21，2023

Terbinafine Hcl Basic information

Product Name:	Terbinafine Hcl
Synonyms:	n-(6,6-dimethyl-2-hepten-4-ynyl)-n-methyl-1-naphthalenemethanamin(e)-1-naphthalenemethanaminmon;Terbinafine Hydrochloride ( China GMP,EDMF Available);Terbinafine-d7 HCl;（E）-N（- 6,6-Dimethyl-2-hepten-4-ynyl）- N-methyl-1-naphthylmethylamine Hydrochloride[Terbinafine Hydrochloride] ;N-[(2E)-6,6-Dimethyl-2-hepten-4-yn-1-yl]-N-methyl-1-naphthalenemethanamine hydrochloride;N-[(E)-6,6-Dimethyl-2-hepten-4-yn-1-yl]-N-methyl-1-naphthalenemethanamine Hydrochloride;TRANS-N-(6,6-DIMETHYL-2-HEPTEN-4-YNYL)-N-METHYL-1-NAPHTHYLMETHYLAMINE HYDROCHLORIDE;(e)-n-(6,6-dimethyl-2-hepten-4-ynyl)-n-methyl-1-naphthalenemethanamine monohydrochloride
CAS:	78628-80-5
MF:	C21H26ClN
MW:	327.89
EINECS:	616-640-4
Product Categories:	Acetylenes;Antifungals for Research and Experimental Use;Biochemistry;Functionalized Acetylenes;Terbinafine;Antifungal;APIs;Amines;Aromatics;Intermediates & Fine Chemicals;Pharmaceuticals;API;78628-80-5;LAMISIL
Mol File:	78628-80-5.mol

Terbinafine Hcl Chemical Properties

Melting point	204-208°C
storage temp.	15-25°C
solubility	methanol: soluble50mg/mL
form	powder
color	white
Merck	14,9156
BCS Class	1
Major Application	pharmaceutical pharmaceutical small molecule
InChI	InChI=1S/C21H25N.ClH/c1-21(2,3)15-8-5-9-16-22(4)17-19-13-10-12-18-11-6-7-14-20(18)19;/h5-7,9-14H,16-17H2,1-4H3;1H/b9-5+;
InChIKey	BWMISRWJRUSYEX-SZKNIZGXSA-N
SMILES	C12C=CC=CC1=CC=CC=2CN(C)C/C=C/C#CC(C)(C)C.Cl
CAS DataBase Reference	78628-80-5(CAS DataBase Reference)

Safety Information

Hazard Codes	Xi,N
Risk Statements	36/37/38-50/53
Safety Statements	26-36/37/39-61-60
RIDADR	UN 3077 9/PG 3
WGK Germany	3
RTECS	QJ8600100
HS Code	29214990
Storage Class	11 - Combustible Solids
Hazard Classifications	Aquatic Acute 1 Aquatic Chronic 1 Eye Irrit. 2 Skin Irrit. 2 STOT SE 3
Toxicity	LD50 in mice, rats (mg/kg): 4000, 4000 orally; 393, 213 i.v. (Ganzinger)

MSDS Information

Terbinafine Hcl Usage And Synthesis

Description	Terbinafine Hcl is a prescription-only medication that is used to treat fungal infections on the skin and nails that are caused by trichophyton. Patients diagnosed with athlete’s foot, jock itch and ringworm use this medication to relieve their symptoms including irritation and burning. Terbinafine Hcl works by reducing the growth of fungi on the skin and nails.
Biological Activity	Terbinafine Hcl is a hydrochloride obtained by reaction of terbinafine with one molar equivalent of hydrogen chloride. It has a role as an EC 1.14.13.132 (squalene monooxygenase) inhibitor and a P450 inhibitor. It is a hydrochloride and an allylamine antifungal drug. It contains a terbinafine(1+).
Side effects	This common side effect of terbinafine Hcl: Peeling or itching skin; Rash; Headache; Diarrhoea; Feeling or being sick (nausea or vomiting); A smaller appetite than usual; Losing your sense of taste; Stomach ache; Indigestion; Muscle or joint pain; Feeling dizzy; Problems with your eyesight.

Terbinafine Hcl Preparation Products And Raw materials

Raw materials	N-Methyl-1-naphthalenemethylamine hydrochloride-->N-Methyl-1-naphthalenemethanamine-->1,3-Dichloropropene-->3,3-Dimethyl-1-butene-->(2E)-N,6,6-trimethyl-2-Hepten-4-yn-1-amine-->Sodium carbonate-->Terbinafine-->Dichloromethane-->1-Methyl-aminomethyl naphthalene-->6,6-Dimethyl-1-hepten-4-yn-3-ol
Preparation Products	Terbinafine

Tag:Terbinafine Hcl(78628-80-5) Related Product Information

1-Chloro-6,6-dimethyl-2-heptene-4-yne 3,3-Dimethyl-1-butyne N-Methyl-1-naphthalenemethylamine hydrochloride Dimethyl ether Dimethyl phthalate Methylamine hydrochloride Dimethyl sulfide Dimethyl fumarate Topotecan hydrochloride Meglumine Trimethylamine Terbinafine hydrochloride N-[(2E)-6,6-DiMethyl-2-hepten-4-yn-1-yl]-N,4-diMethyl-1-naphthaleneMethanaMine Hydrochloride Dimethyl sulfoxide N,N-Dimethylformamide Flunixin Meglumin Ethane N-[(2E)-6,6-DiMethyl-2-hepten-4-yn-1-yl]-N-Methyl-2-naphthaleneMethanaMine Hydrochloride