VU 0463841

VU 0463841 Suppliers list

Company Name:	TargetMol Chemicals Inc.
Tel:	+1-781-999-5354;
Email:	support@targetmol.com
Products Intro:	Product Name:VU0463841；VU-0463841;VU 0463841 CAS:1439095-16-5 Package:100 mg；500 mg Remarks:REAGENT;FOR LABORATORY USE ONLY

Company Name:	Wuhan Han Sheng New Material Technology Co.，Ltd
Tel:	+8617798174412
Email:	admin01@hsnm.com.cn
Products Intro:	Product Name:VU0463841；VU-0463841;VU 0463841 CAS:1439095-16-5 Purity:0.99 Package:5KG;1KG

Company Name:	TargetMol Chemicals Inc.
Tel:	+17819995354
Email:	marketing@targetmol.com
Products Intro:	Product Name:VU0463841 CAS:1439095-16-5 Package:100mg;2500USD\|25mg;1520USD\|50mg;1980USD

Company Name:	TargetMol Chemicals Inc.
Tel:	15002134094
Email:	marketing@targetmol.cn
Products Intro:	Product Name:VU0463841 CAS:1439095-16-5 Package:100mg/RMB 17500;25mg/RMB 10600;50mg/RMB 13800

VU 0463841 manufacturers

VU 0463841 Basic information

VU 0463841 Chemical Properties

Safety Information

MSDS Information

VU 0463841 Usage And Synthesis

Description	VU0463841 is a negative allosteric modulators of mGlu5.
Uses	VU0463841 is a potent, selective and brain-penetrant mGlu5 negative allosteric modulator (NAM) with an IC50 of 13 nM. VU0463841 is ineffective against mGlu1-4 and mGlu7-8. VU0463841 has the potential for the Cocaine addiction research[1].
IC 50	mGlu5 Receptor: 13 nM (IC₅₀)
References	[1] Russell J Amato, et al. Substituted 1-Phenyl-3-(pyridin-2-yl)urea negative allosteric modulators of mGlu5: discovery of a new tool compound VU0463841 with activity in rat models of cocaine addiction. ACS Chem Neurosci. 2013 Aug 21;4(8):1217-28. DOI:10.1021/cn400070k

VU 0463841 Preparation Products And Raw materials

Tag:VU 0463841(1439095-16-5) Related Product Information

[Hexahydro-5-(4-pyridinyl)pyrrolo[3,4-c]pyrrol-2(1H)-yl][1-(5-isoquinolinylsulfonyl)-3-azetidinyl]-Methanone N-(5-chloro-2-methoxyphenyl)-2-[4-(4-methylpiperidin-1-yl)sulfonylpiperazin-1-yl]acetamide VU0453595 VU 0364439 5-[1-(2-ethoxyphenyl)sulfonylazetidin-3-yl]-3-thiophen-3-yl-1,2,4-oxadiazole VU 0360223 2(5H)-Furanone, 3-(3-fluorophenyl)-4-(4-methoxyphenyl)- VU 0360172 cyclopentyl 1,6-dimethyl-4-(6-nitro-1,3-benzodioxol-5-yl)-2-oxo-1,2,3,4-tetrahydropyrimidine-5-carboxylate N-[3-Oxo-3-[4-(4-pyridinyl)-1-piperazinyl]propyl]-2,1,3-benzothiadiazole-4-sulfonamide (1R,2R)-N-([S]-1-{4-[5-broMo-2-oxo-2,3-dihydro-1H-benzo(d)iMidazol-1-yl]piperidin-1-yl}propan-2-yl)-2-phenylcyclopropanecarboxaMide Urea, N-(3,4-difluorophenyl)-N'-[3-methyl-1-(phenylmethyl)-1H-pyrazol-5-yl]- VU-0486321 VU0238441 VU0483605 VU0453379 VU0810464 VU-0410150

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