N-[3-Oxo-3-[4-(4-pyridinyl)-1-piperazinyl]propyl]-2,1,3-benzothiadiazole-4-sulfonamide

N-[3-Oxo-3-[4-(4-pyridinyl)-1-piperazinyl]propyl]-2,1,3-benzothiadiazole-4-sulfonamide Suppliers list

Company Name:	TargetMol Chemicals Inc.
Tel:	+1-781-999-5354; +1-00000000000
Email:	marketing@targetmol.com
Products Intro:	Product Name:VU 0255035 CAS:1135243-19-4 Purity:98.26% Package:5mg;43USD\|10mg;73USD\|25mg;155USD Remarks:REAGENT;FOR LABORATORY USE ONLY

Company Name:	Hefei TNJ Chemical Industry Co.,Ltd.
Tel:	+86-0551-65418684 +86-18949823763
Email:	sales@tnjchem.com
Products Intro:	Product Name:N-{3-Oxo-3-[4-(4-pyridinyl)-1-piperazinyl]propyl}-2,1,3-benz... CAS:1135243-19-4

Company Name:	Wuhan Topule Biopharmaceutical Co., Ltd
Tel:	+86-18327326525
Email:	masar@topule.com
Products Intro:	Product Name:VU 0255035 CAS:1135243-19-4 Purity:98%+ Package:100mg;1g;500g Remarks:Topule Company operates with integrity and has its own laboratory, which supports packaging and customization. Payment will be made after the product has passed third-party testing

Company Name:	Aladdin Scientific
Tel:
Email:	tp@aladdinsci.com
Products Intro:	Product Name:VU0255035 CAS:1135243-19-4 Purity:>=98% Package:$42.9/2mg;$88.9/5mg;$147.9/10mg;$310.9/25mg;$559.9/50mg;$1007.9/100mg;$2267.9/25 Remarks:98%

Company Name:	DAYANG CHEM (HANGZHOU) CO.,LTD
Tel:	+86-88938639 +86-17705817739
Email:	info@dycnchem.com
Products Intro:	Product Name:VU255035 hydrate CAS:1135243-19-4 Purity:0.95&0.99 Package:0.1KG;1KG;1000KG Remarks:Hot selling

N-[3-Oxo-3-[4-(4-pyridinyl)-1-piperazinyl]propyl]-2,1,3-benzothiadiazole-4-sulfonamide manufacturers

N-[3-Oxo-3-[4-(4-pyridinyl)-1-piperazinyl]propyl]-2,1,3-benzothiadiazole-4-sulfonamide Basic information

Product Name:	N-[3-Oxo-3-[4-(4-pyridinyl)-1-piperazinyl]propyl]-2,1,3-benzothiadiazole-4-sulfonamide
Synonyms:	N-[3-Oxo-3-[4-(4-pyridinyl)-1-piperazinyl]propyl]-2,1,3-benzothiadiazole-4-sulfonamide;VU 0255035;N-(3-Oxo-3-(4-(pyridin-4-yl)piperazin-1-yl)propyl)benzo[c][1,2,5]thiadiazole-4-sulfonaMide;CID24768606;ML012;N-(3-oxo-3-(4-(pyridine-4-yl)piperazin-1-yl)propyl)benzo[c][1,2,5]thiadiazole-4-sulfonamide hydrate;N-[3-oxo-3-[4-(4-pyridinyl)-1-piperazinyl]propyl]-2,1,3-benzothiadiazole-4-sulfonamide hydrate;VU0255035 hydrate
CAS:	1135243-19-4
MF:	C18H20N6O3S2
MW:	432.52
EINECS:
Product Categories:
Mol File:	1135243-19-4.mol

N-[3-Oxo-3-[4-(4-pyridinyl)-1-piperazinyl]propyl]-2,1,3-benzothiadiazole-4-sulfonamide Chemical Properties

Melting point	159.7-160.2 °C(Solv: dichloromethane (75-09-2); hexane (110-54-3))
Boiling point	689.3±65.0 °C(Predicted)
density	1.447±0.06 g/cm3(Predicted)
storage temp.	Store at -20°C
solubility	DMSO: >5mg/mL
form	powder
pka	8.97±0.50(Predicted)
color	yellow
InChI	1S/C18H20N6O3S2.H2O/c25-17(24-12-10-23(11-13-24)14-4-7-19-8-5-14)6-9-20-29(26,27)16-3-1-2-15-18(16)22-28-21-15;/h1-5,7-8,20H,6,9-13H2;1H2
InChIKey	NURHGMDBQMBSQI-UHFFFAOYSA-N
SMILES	O.O=C(CCNS(=O)(=O)c1cccc2nsnc12)N3CCN(CC3)c4ccncc4

Safety Information

Hazard Codes	Xn
Risk Statements	22-36/37/38
Safety Statements	26
WGK Germany	3
Storage Class	11 - Combustible Solids
Hazard Classifications	Acute Tox. 4 Oral Eye Irrit. 2 Skin Irrit. 2 STOT SE 3

MSDS Information

N-[3-Oxo-3-[4-(4-pyridinyl)-1-piperazinyl]propyl]-2,1,3-benzothiadiazole-4-sulfonamide Usage And Synthesis

Uses	VU 0255035 is a novel, selective antagonist of M1 mAChRs, which has potential treatment in CNS disorders.
Definition	ChEBI: N-[3-oxo-3-(4-pyridin-4-yl-1-piperazinyl)propyl]-2,1,3-benzothiadiazole-4-sulfonamide is a member of pyridines and a member of piperazines.
Biological Activity	VU0255035 is the first highly selective antagonist at the orthosteric site of the M1 receptor (75-fold selective for M1 relative to other muscarininc subtypes and devoid of activity at other GPCRs, ion channels, transporters and kinases). There are no highly selective M1 muscarinic receptor antagonists. The existing non-selective drugs do not permit direct evaluation of the role of M1 receptors in CNS fucntions and do not premit therapeutic targeting of M1 receptors in various disease states in which M1 receptors are implicated (epilepsy, Parkinsonμs disease, attention and cognitive disorders, dystonia, etc).
storage	Store at -20°C

N-[3-Oxo-3-[4-(4-pyridinyl)-1-piperazinyl]propyl]-2,1,3-benzothiadiazole-4-sulfonamide Preparation Products And Raw materials

Tag:N-[3-Oxo-3-[4-(4-pyridinyl)-1-piperazinyl]propyl]-2,1,3-benzothiadiazole-4-sulfonamide(1135243-19-4) Related Product Information

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