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| | Vitexilactone Basic information |
| Product Name: | Vitexilactone | | Synonyms: | (1R,3R,4R,4aS,8aS)-4-Hydroxy-3,4a,8,8-tetramethyl-4-[2-(5-oxo-2,5-dihydro-3-furanyl)ethyl]decahydro-1-naphthalenyl acetate;4-[2-[(1R,4aα)-Decahydro-4β-acetoxy-1α-hydroxy-2α,5,5,8aβ-tetramethylnaphthalen-1-yl]ethyl]furan-2(5H)-one;4-[2-[(4aα)-4β-Acetoxy-1-hydroxy-2α,5,5,8aβ-tetramethyldecalin-1β-yl]ethyl]-2(5H)-furanone;[(1R,3R,4R,4aS,8aS)-4-hydroxy-3,4a,8,8-tetramethyl-4-[2-(5-oxo-2H-furan-3-yl)ethyl]-2,3,5,6,7,8a-hexahydro-1H-naphthalen-1-yl] acetate;2(5H)-Furanone, 4-[2-[(1R,2R,4R,4aS,8aS)-4-(acetyloxy)decahydro-1-hydroxy-2,5,5,8a-tetramethyl-1-naphthalenyl]ethyl]- | | CAS: | 61263-49-8 | | MF: | C22H34O5 | | MW: | 378.5 | | EINECS: | | | Product Categories: | | | Mol File: | 61263-49-8.mol |  |
| | Vitexilactone Chemical Properties |
| Melting point | 148～149℃ | | Boiling point | 501.5±40.0 °C(Predicted) | | density | 1.13±0.1 g/cm3(Predicted) | | solubility | Soluble in Chloroform,Dichloromethane,Ethyl Acetate,DMSO,Acetone,etc. | | form | Powder | | pka | 14.51±0.70(Predicted) |
| | Vitexilactone Usage And Synthesis |
| Uses | Vitexilactone is a diterpenoid that can be isolated from the leaves of Vitex negundo L. Vitexilactone shows antimicrobial activity towards E. coli. Vitexilactone induces cell apoptosis and inhibits cell cycle of cancer cells. Vitexilactone can be used for the research of cancer[1][2]. | | Definition | ChEBI: A labdane diterpenoid that is isolated from the fruits of Vitex trifolia L. and Vitex agnus-castus | | target | HIV | NADPH-oxidase | Antifection | | References | [1] Sichaem J, et al. A new labdane-type diterpenoid from the leaves of Vitex negundo L. Nat Prod Res. 2021 Jul;35(14):2329-2334. DOI:10.1080/14786419.2019.1672687
[2] Li WX, et al. Labdane-type diterpenes as new cell cycle inhibitors and apoptosis inducers from Vitex trifolia L. J Asian Nat Prod Res. 2005 Apr;7(2):95-105. DOI:10.1080/10286020310001617165 |
| | Vitexilactone Preparation Products And Raw materials |
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